Page last updated: 2024-10-31

metronidazole and Hypokalemia

metronidazole has been researched along with Hypokalemia in 2 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mojadidi, MK1
Hovnanians, N1
Kaufmann, MR1
Hill, JA1
Yelve, K1
Phatak, S1
Patil, MA1
Pazare, AR1

Other Studies

2 other studies available for metronidazole and Hypokalemia

ArticleYear
An Unusual Presentation of QT Prolongation.
    Texas Heart Institute journal, 2016, Volume: 43, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Action Potentials; Anti-Infective Agents; Arrhythmias, Card

2016
Syncope in a patient being treated for hepatic and intestinal amoebiasis.
    BMJ case reports, 2012, Nov-30, Volume: 2012

    Topics: Amebicides; Antiprotozoal Agents; Chloroquine; Dysentery, Amebic; Furans; Humans; Hypokalemia; Liver

2012