metronidazole has been researched along with Hypoglycemia in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the risk of hypoglycemia and associated costs in older patients prescribed glipizide or glyburide who fill a prescription for an antimicrobial drug." | 3.80 | Hypoglycemia after antimicrobial drug prescription for older patients using sulfonylureas. ( Goodwin, JS; Kuo, YF; Lin, YL; Parekh, TM; Raji, M; Tan, A, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parekh, TM | 1 |
| Raji, M | 1 |
| Lin, YL | 1 |
| Tan, A | 1 |
| Kuo, YF | 1 |
| Goodwin, JS | 1 |
| Sharma, P | 1 |
| Eesa, M | 1 |
| Scott, JN | 1 |
1 review available for metronidazole and Hypoglycemia
| Article | Year |
|---|---|
Toxic and acquired metabolic encephalopathies: MRI appearance.
Topics: Brain Diseases, Metabolic; Carbon Monoxide Poisoning; Cocaine; Cyclosporine; Diagnosis, Differential | 2009 |
1 other study available for metronidazole and Hypoglycemia
| Article | Year |
|---|---|
Hypoglycemia after antimicrobial drug prescription for older patients using sulfonylureas.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Drug Interactions; Dr | 2014 |