metronidazole has been researched along with Hypertrichosis in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Hypertrichosis: Excessive hair growth at inappropriate locations, such as on the extremities, the head, and the back. It is caused by genetic or acquired factors, and is an androgen-independent process. This concept does not include HIRSUTISM which is an androgen-dependent excess hair growth in WOMEN and CHILDREN.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
HOLSTEIN, AP | 1 |
Curreli, A | 1 |
Massidda, B | 1 |
Leo, P | 1 |
Scarpellini, L | 1 |
Vizzone, A | 1 |
Calugi, A | 1 |
Lanzone, P | 1 |
3 other studies available for metronidazole and Hypertrichosis
Article | Year |
---|---|
THE ANTIHIRSUTISM ACTIVITY OF METRANIDAZOLE.
Topics: Antiprotozoal Agents; Drug Therapy; Hirsutism; Humans; Hypertrichosis; Imidazoles; Metronidazole; Sc | 1964 |
[Action of topical metronidazole on hypertrichosis].
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Drug Evaluation; Female; Humans; Hypertri | 1973 |
[Anti-androgenic activity of hydroxy-2-methyl-1-methyl-2-nitro-5-imidazole in gynecology. (Clinical study, hormone elimination and colpocytological aspects in some cases of hypertrichosis)].
Topics: Adult; Androgens; Estrogens; Female; Glucocorticoids; Humans; Hypertrichosis; Menstruation Disturban | 1967 |