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metronidazole and Hypertrichosis

metronidazole has been researched along with Hypertrichosis in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Hypertrichosis: Excessive hair growth at inappropriate locations, such as on the extremities, the head, and the back. It is caused by genetic or acquired factors, and is an androgen-independent process. This concept does not include HIRSUTISM which is an androgen-dependent excess hair growth in WOMEN and CHILDREN.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HOLSTEIN, AP1
Curreli, A1
Massidda, B1
Leo, P1
Scarpellini, L1
Vizzone, A1
Calugi, A1
Lanzone, P1

Other Studies

3 other studies available for metronidazole and Hypertrichosis

ArticleYear
THE ANTIHIRSUTISM ACTIVITY OF METRANIDAZOLE.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Antiprotozoal Agents; Drug Therapy; Hirsutism; Humans; Hypertrichosis; Imidazoles; Metronidazole; Sc

1964
[Action of topical metronidazole on hypertrichosis].
    Atti della Accademia medica lombarda, 1973, Volume: 28, Issue:1-4

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Drug Evaluation; Female; Humans; Hypertri

1973
[Anti-androgenic activity of hydroxy-2-methyl-1-methyl-2-nitro-5-imidazole in gynecology. (Clinical study, hormone elimination and colpocytological aspects in some cases of hypertrichosis)].
    Quaderni di clinica ostetrica e ginecologica, 1967, Volume: 22, Issue:11

    Topics: Adult; Androgens; Estrogens; Female; Glucocorticoids; Humans; Hypertrichosis; Menstruation Disturban

1967