metronidazole has been researched along with Hyperthyroidism in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, DI | 1 |
| González-Bárcena, D | 1 |
| Gómez-Leal, A | 1 |
| Ocampo-Campos, R | 1 |
| Portioli, I | 1 |
| Rocchi, F | 1 |
| Maraini, G | 1 |
| Pescatori, A | 1 |
1 trial available for metronidazole and Hyperthyroidism
| Article | Year |
|---|---|
The effect of metronidazole on exophthalmos in man.
Topics: Antithyroid Agents; Clinical Trials as Topic; Exophthalmos; Feeding and Eating Disorders; Humans; Hy | 1968 |
2 other studies available for metronidazole and Hyperthyroidism
| Article | Year |
|---|---|
[Treatment with metronidazole of endocrine exophthalmos].
Topics: Evaluation Studies as Topic; Exophthalmos; Female; Humans; Hyperthyroidism; Male; Metronidazole; Thy | 1973 |
[On the anti-exophthalmic and anti-thyroid action of an imidazole derivative with trichomonacidal action: metronidazole].
Topics: Adolescent; Adult; Exophthalmos; Female; Graves Disease; Humans; Hyperthyroidism; Male; Metronidazol | 1968 |