metronidazole has been researched along with Hirsutism in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Hirsutism: A condition observed in WOMEN and CHILDREN when there is excess coarse body hair of an adult male distribution pattern, such as facial and chest areas. It is the result of elevated ANDROGENS from the OVARIES, the ADRENAL GLANDS, or exogenous sources. The concept does not include HYPERTRICHOSIS, which is an androgen-independent excessive hair growth.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
HOLSTEIN, AP | 1 |
Dolian, GG | 1 |
Wahlén, T | 1 |
Astedt, B | 1 |
Cairella, M | 1 |
Nasta, G | 1 |
1 review available for metronidazole and Hirsutism
Article | Year |
---|---|
[Hirsutism].
Topics: Androgens; Castration; Circadian Rhythm; Cyproterone; Estradiol Congeners; Ethnicity; Female; Hirsut | 1981 |
3 other studies available for metronidazole and Hirsutism
Article | Year |
---|---|
THE ANTIHIRSUTISM ACTIVITY OF METRANIDAZOLE.
Topics: Antiprotozoal Agents; Drug Therapy; Hirsutism; Humans; Hypertrichosis; Imidazoles; Metronidazole; Sc | 1964 |
[Hirsutism and steroid excretion under metronidazole treatment].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adult; Female; Hirsutism; | 1965 |
[Therapy of simple or idiopathic hirsutism].
Topics: Adrenal Cortex Hormones; Estrogens; Female; Hirsutism; Humans; Metronidazole | 1966 |