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metronidazole and Hirsutism

metronidazole has been researched along with Hirsutism in 4 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Hirsutism: A condition observed in WOMEN and CHILDREN when there is excess coarse body hair of an adult male distribution pattern, such as facial and chest areas. It is the result of elevated ANDROGENS from the OVARIES, the ADRENAL GLANDS, or exogenous sources. The concept does not include HYPERTRICHOSIS, which is an androgen-independent excessive hair growth.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HOLSTEIN, AP1
Dolian, GG1
Wahlén, T1
Astedt, B1
Cairella, M1
Nasta, G1

Reviews

1 review available for metronidazole and Hirsutism

ArticleYear
[Hirsutism].
    Akusherstvo i ginekologiia, 1981, Issue:2

    Topics: Androgens; Castration; Circadian Rhythm; Cyproterone; Estradiol Congeners; Ethnicity; Female; Hirsut

1981

Other Studies

3 other studies available for metronidazole and Hirsutism

ArticleYear
THE ANTIHIRSUTISM ACTIVITY OF METRANIDAZOLE.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Antiprotozoal Agents; Drug Therapy; Hirsutism; Humans; Hypertrichosis; Imidazoles; Metronidazole; Sc

1964
[Hirsutism and steroid excretion under metronidazole treatment].
    Nordisk medicin, 1965, Oct-28, Volume: 74, Issue:43

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adult; Female; Hirsutism;

1965
[Therapy of simple or idiopathic hirsutism].
    La Clinica terapeutica, 1966, Sep-15, Volume: 38, Issue:5

    Topics: Adrenal Cortex Hormones; Estrogens; Female; Hirsutism; Humans; Metronidazole

1966