metronidazole has been researched along with Hemorrhage, Uterine in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methotrexate (MTX) is an antimetabolite of folic acid, which is used for management of ectopic pregnancy." | 5.01 | Low-dose methotrexate-induced vulvar edema: A case report. ( Chai, W; Cui, L; Gong, F; He, Z; Jia, G; Liu, X; Wen, Y, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, G | 1 |
| Chai, W | 1 |
| He, Z | 1 |
| Liu, X | 1 |
| Wen, Y | 1 |
| Cui, L | 1 |
| Gong, F | 1 |
| Steudel, HC | 1 |
| Gugler, R | 1 |
| Weissman, A | 1 |
| Elhalal, U | 1 |
| Blickstein, I | 1 |
| Caspi, B | 1 |
| Larsson, PG | 1 |
| Bergman, B | 1 |
| Forsum, U | 1 |
| Påhlson, C | 1 |
| Crichton, D | 1 |
| Knobel, J | 1 |
| Farkas, G | 2 |
1 review available for metronidazole and Hemorrhage, Uterine
| Article | Year |
|---|---|
Low-dose methotrexate-induced vulvar edema: A case report.
Topics: Abdominal Pain; Administration, Oral; Adult; China; Female; Glycyrrhizic Acid; Humans; Injections, I | 2019 |
1 trial available for metronidazole and Hemorrhage, Uterine
| Article | Year |
|---|---|
Treatment of bacterial vaginosis in women with vaginal bleeding complications or discharge and harboring Mobiluncus.
Topics: Adult; Bacteria, Anaerobic; Bacterial Infections; Double-Blind Method; Drug Administration Schedule; | 1990 |
4 other studies available for metronidazole and Hemorrhage, Uterine
| Article | Year |
|---|---|
[Postpartum pseudomembranous colitis].
Topics: Adult; Cefotaxime; Colon; Colonoscopy; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; F | 1984 |
Self-induced abortion--the peril is still real.
Topics: Abortion, Induced; Abortion, Missed; Adult; Cefazolin; Curettage; Drug Combinations; Female; Gentami | 1992 |
The principles of prevention of avoidable maternal death. A study of 538 consecutive maternal deaths in the obstetric unit, King Edward 8th Hospital, Durban, 1953-1971.
Topics: Anesthesia, Inhalation; Anesthesia, Obstetrical; Cesarean Section; Dysentery, Amebic; Emergencies; F | 1973 |
[Proceedings: Is hemorrhage in early pregnancy and its drug therapy an increased risk of teratogenesis?].
Topics: Abnormalities, Drug-Induced; Abortion, Threatened; Allyl Compounds; Aminopyrine; Chlordiazepoxide; C | 1973 |