metronidazole has been researched along with Growth Disorders in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Growth Disorders: Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrianov, M | 1 |
| Rivera, E | 1 |
| Azzam, R | 1 |
| Goto, R | 1 |
| Mascie-Taylor, CG | 1 |
| Lunn, PG | 1 |
| Lopriore, C | 1 |
| Guidoum, Y | 1 |
| Briend, A | 1 |
| Branca, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Anti-Giardia and Antihelmintic Treatment on Infant Nutritional and Biochemical Status and Intestinal Permeability in Rural Bangladesh[NCT00607074] | 410 participants (Actual) | Interventional | 2003-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for metronidazole and Growth Disorders
| Article | Year |
|---|---|
Impact of anti-Giardia and anthelminthic treatment on infant growth and intestinal permeability in rural Bangladesh: a randomised double-blind controlled study.
Topics: Albendazole; Animals; Anthelmintics; Anthropometry; Antiprotozoal Agents; Bangladesh; Breast Feeding | 2009 |
Spread fortified with vitamins and minerals induces catch-up growth and eradicates severe anemia in stunted refugee children aged 3-6 y.
Topics: Algeria; Analysis of Variance; Anemia, Iron-Deficiency; Body Height; Child; Child, Preschool; Double | 2004 |
1 other study available for metronidazole and Growth Disorders
| Article | Year |
|---|---|
A 15-year-old boy with abdominal pain, growth retardation, and anemia secondary to Helicobacter pylori-associated peptic ulcer.
Topics: Adolescent; Amoxicillin; Anemia, Iron-Deficiency; Clarithromycin; Drug Therapy, Combination; Growth | 2015 |