Page last updated: 2024-10-31

metronidazole and Grippe

metronidazole has been researched along with Grippe in 2 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"Afebrile seizures associated with rotavirus gastroenteritis, respiratory syncytial virus bronchiolitis, influenza infection, asthma, blood transfusions, and intake of a number of drugs (including theophylline, cephalosporins, metronidazole, and acyclovir) with therapeutic drug levels are uncommonly encountered in clinical practice."4.85Common causes of uncommon seizures. ( Boustany, RM; El-Bitar, MK, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
El-Bitar, MK1
Boustany, RM1
West, SD1
Brunskill, NJ1

Reviews

1 review available for metronidazole and Grippe

ArticleYear
Common causes of uncommon seizures.
    Pediatric neurology, 2009, Volume: 41, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antiviral Agents; Asthma; Brain; Bronchiolitis; Child;

2009

Other Studies

1 other study available for metronidazole and Grippe

ArticleYear
Complications associated with influenza infection.
    Postgraduate medical journal, 2002, Volume: 78, Issue:916

    Topics: Acute Kidney Injury; Alphainfluenzavirus; Drug Therapy, Combination; Humans; Imipenem; Influenza, Hu

2002
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