metronidazole has been researched along with Glandular Fever in 9 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole may be of use in the treatment of infectious mononucleosis (IM)." | 9.19 | Effect of metronidazole versus standard care on length of stay of patients admitted with severe infectious mononucleosis: a randomized controlled trial. ( Fenton, JE; Lennon, P; O'Neill, JP, 2014) |
| "16 patients with the anginose type of infectious mononucleosis were treated with metronidazole, and another 3 patients were given clindamycin." | 9.04 | Treatment of anginose infectious mononucleosis with metronidazole. ( Hedström, SA; Mårdh, PA; Ripa, T, 1978) |
| "Metronidazole treatment resulted in a more rapid regression of tonsillitis note on the 4th day in both treated groups and a faster defervescence noted on the 3rd day compared to controls." | 7.75 | Treatment of anginose infectious mononucleosis with metronidazole. A controlled clinical and laboratory study. ( Hedström, SA, 1980) |
| "Metronidazole may be of use in the treatment of infectious mononucleosis (IM)." | 5.19 | Effect of metronidazole versus standard care on length of stay of patients admitted with severe infectious mononucleosis: a randomized controlled trial. ( Fenton, JE; Lennon, P; O'Neill, JP, 2014) |
| "16 patients with the anginose type of infectious mononucleosis were treated with metronidazole, and another 3 patients were given clindamycin." | 5.04 | Treatment of anginose infectious mononucleosis with metronidazole. ( Hedström, SA; Mårdh, PA; Ripa, T, 1978) |
| "Metronidazole treatment resulted in a more rapid regression of tonsillitis note on the 4th day in both treated groups and a faster defervescence noted on the 3rd day compared to controls." | 3.75 | Treatment of anginose infectious mononucleosis with metronidazole. A controlled clinical and laboratory study. ( Hedström, SA, 1980) |
| "Acute dacryocystitis is a rare complication of infectious mononucleosis with only three previous reports in the English literature." | 1.37 | Acute dacryocystitis associated with epstein-barr virus infection. ( Clarke, JL; Ghauri, AJ; Keane, PA; Madge, SN; Scotcher, SM, 2011) |
| "24 days after the onset of infectious mononucleosis, clinically and serologically confirmed, an otherwise healthy 18-year-old schoolboy developed a fulminant septicaemia with acute meningitis and loss of consciousness, consumptive coagulopathy and acute renal failure." | 1.29 | [Lemierre's post-tonsillitis sepsis with meningitis and intravascular consumption coagulopathy as complication of infectious mononucleosis with pansinusitis]. ( Busch, N; Haase, G; Kierdorf, H; Marschall, HU; Matern, S; Mertens, PR; Nguyen, H; Schönfelder, T; Sieberth, HG; Urhahn, R, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lennon, P | 1 |
| O'Neill, JP | 1 |
| Fenton, JE | 1 |
| Ghauri, AJ | 1 |
| Keane, PA | 1 |
| Scotcher, SM | 1 |
| Clarke, JL | 1 |
| Madge, SN | 1 |
| Spelman, DW | 1 |
| Newton-John, HF | 1 |
| Hedström, SA | 2 |
| Clemmons, LH | 1 |
| Davidson, S | 2 |
| Kaplinsky, C | 1 |
| Frand, M | 2 |
| Rotem, J | 1 |
| Busch, N | 1 |
| Mertens, PR | 1 |
| Schönfelder, T | 1 |
| Nguyen, H | 1 |
| Marschall, HU | 1 |
| Kierdorf, H | 1 |
| Haase, G | 1 |
| Urhahn, R | 1 |
| Sieberth, HG | 1 |
| Matern, S | 1 |
| Rotem, Y | 1 |
| Mårdh, PA | 1 |
| Ripa, T | 1 |
1 review available for metronidazole and Glandular Fever
| Article | Year |
|---|---|
Treatment of anginose infectious mononucleosis with metronidazole. A controlled clinical and laboratory study.
Topics: Adolescent; Adult; C-Reactive Protein; Clinical Trials as Topic; Female; Humans; Infectious Mononucl | 1980 |
4 trials available for metronidazole and Glandular Fever
| Article | Year |
|---|---|
Effect of metronidazole versus standard care on length of stay of patients admitted with severe infectious mononucleosis: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Humans; Infectious Mononu | 2014 |
Metronidazole in the treatment of anginose infectious mononucleosis.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Double-Blind Method; Female; Herpesvirus 4, Huma | 1982 |
Treatment of anginose infectious mononucleosis with metronidazole. A controlled clinical and laboratory study.
Topics: Adolescent; Adult; C-Reactive Protein; Clinical Trials as Topic; Female; Humans; Infectious Mononucl | 1980 |
Treatment of anginose infectious mononucleosis with metronidazole.
Topics: Adolescent; Adult; Body Temperature; Child; Clindamycin; Deglutition; Drug Evaluation; Female; Human | 1978 |
5 other studies available for metronidazole and Glandular Fever
| Article | Year |
|---|---|
Acute dacryocystitis associated with epstein-barr virus infection.
Topics: Acute Disease; Ceftriaxone; Child; Child, Preschool; Combined Modality Therapy; Dacryocystitis; Drai | 2011 |
Shingles, herpes, sex and mononucleosis.
Topics: Drug Therapy, Combination; Herpes Simplex; Herpes Zoster; Humans; Infectious Mononucleosis; Male; Me | 1982 |
Treatment of infectious mononucleosis with metronidazole in the pediatric age group.
Topics: Adolescent; Child; Child, Preschool; Humans; Infectious Mononucleosis; Metronidazole; Prospective St | 1982 |
[Lemierre's post-tonsillitis sepsis with meningitis and intravascular consumption coagulopathy as complication of infectious mononucleosis with pansinusitis].
Topics: Acute Kidney Injury; Adolescent; Anti-Bacterial Agents; Bacteremia; Chloramphenicol; Disseminated In | 1996 |
[Treatment of infectious mononucleosis with metronidazole].
Topics: Humans; Infectious Mononucleosis; Metronidazole | 1979 |