Page last updated: 2024-10-31

metronidazole and Gingivitis

metronidazole has been researched along with Gingivitis in 54 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Gingivitis: Inflammation of gum tissue (GINGIVA) without loss of connective tissue.

Research Excerpts

ExcerptRelevanceReference
"To compare the effectiveness of metronidazole gel and mobile telephone short-message service (SMS) reminders on gingivitis in patients undergoing fixed orthodontic treatment."9.41Effectiveness of metronidazole gel and mobile telephone short-message service reminders on gingivitis in orthodontic patients. ( Afzal, E; Fatima, F; Fida, M; Irfan, S; Mahmood, HT; Malik, D; Sukhia, RH; Younus, A, 2021)
" The aim of this study was to compare interleukin-1β (IL-1β) and chemokine (C-C motif) ligand 28 (CCL28) levels following a topical application of curcumin (CRM), chlorhexidine (CHX) and chlorhexidine-metronidazole (CHX-MTZ) in an experimental gingivitis human model."9.20Effects of curcumin on crevicular levels of IL-1β and CCL28 in experimental gingivitis. ( Nath, S; Pulikkotil, SJ, 2015)
"One hundred twenty subjects diagnosed with chronic generalized gingivitis were selected and randomly divided into four groups: Group 1--placebo gel, Group 2--chlorhexidine (CHX) gel, Group 3--metronidazole (MTZ) gel and Group 4--chlorhexidine-metronidazole (CHX-MTZ) gel."9.16Efficacy of chlorhexidine, metronidazole and combination gel in the treatment of gingivitis--a randomized clinical trial. ( Kumari, M; Naik, SB; Pradeep, AR; Priyanka, N, 2012)
"The present study describes results on selected clinical and microbiological parameters obtained by treatment with local (Elyzol) and systemic (Flagyl) use of metronidazole alone and/or mechanical subgingival debridement in adult periodontitis."9.08A clinical and microbiological evaluation of systemic and local metronidazole delivery in adult periodontitis patients. ( Acar, O; Büget, E; Kadir, T; Kuru, B; Noyan, U; Yilmaz, S, 1997)
"After baseline clinical and microbiological monitoring, 17 adult periodontitis subjects received full mouth SRP and 14 days systemic administration of either metronidazole (250 mg, TID, n=8) or amoxicillin (500 mg, TID, n=9)."7.71Change in subgingival microbial profiles in adult periodontitis subjects receiving either systemically-administered amoxicillin or metronidazole. ( Allard, K; Feres, M; Haffajee, AD; Socransky, SS; Som, S, 2001)
"The present investigation was performed in order to assess if the administration of metronidazole changed the composition of developing plaque in dogs, which at the start of the study were free from signs of gingivitis."7.66The effect of metronidazole on the development of plaque and gingivitis in the beagle dog. ( Heijl, L; Lindhe, J, 1979)
"As a healthcare profession, dentists have a role in ensuring the safety of prescribed medicines by reporting adverse drug reactions using the Yellow Card Scheme."6.53Metronidazole and tinnitus: A potential side effect? ( Barker, D; O'Donnell, KL, 2016)
"Gingivitis is a condition that needs sustained concentration of antibiotic locally over extended period of time."5.62Optimization of metronidazole SR buccal tablet for gingivitis using genetic algorithm. ( Ali, S; Hanif, S; Iqbal, Z; Irfan, M; Khan, I; Mujtaba, SH; Niaz, Y; Raza, S; Raza, SA; Razzaq, S; Sarfraz, RM; Shakir, R; Syed, MA, 2021)
" The aim of this study was to compare interleukin-1β (IL-1β) and chemokine (C-C motif) ligand 28 (CCL28) levels following a topical application of curcumin (CRM), chlorhexidine (CHX) and chlorhexidine-metronidazole (CHX-MTZ) in an experimental gingivitis human model."5.20Effects of curcumin on crevicular levels of IL-1β and CCL28 in experimental gingivitis. ( Nath, S; Pulikkotil, SJ, 2015)
"One hundred twenty subjects diagnosed with chronic generalized gingivitis were selected and randomly divided into four groups: Group 1--placebo gel, Group 2--chlorhexidine (CHX) gel, Group 3--metronidazole (MTZ) gel and Group 4--chlorhexidine-metronidazole (CHX-MTZ) gel."5.16Efficacy of chlorhexidine, metronidazole and combination gel in the treatment of gingivitis--a randomized clinical trial. ( Kumari, M; Naik, SB; Pradeep, AR; Priyanka, N, 2012)
"The present study describes results on selected clinical and microbiological parameters obtained by treatment with local (Elyzol) and systemic (Flagyl) use of metronidazole alone and/or mechanical subgingival debridement in adult periodontitis."5.08A clinical and microbiological evaluation of systemic and local metronidazole delivery in adult periodontitis patients. ( Acar, O; Büget, E; Kadir, T; Kuru, B; Noyan, U; Yilmaz, S, 1997)
"This study assessed the subgingival occurrence of the flagellated, Gram-negative, anaerobic rod Centipeda periodontii in chronic periodontitis and periodontal health/gingivitis with species-specific nucleic acid probes, and evaluated the in vitro resistance of subgingival isolates to therapeutic levels of amoxicillin, metronidazole, and doxycycline."3.81Centipeda periodontii in human periodontitis. ( Degener, JE; Hawley, CE; Rams, TE; van Winkelhoff, AJ; Whitaker, EJ, 2015)
" Systemic administration of combinations of metronidazole and either amoxicillin or ciprofloxacin has been widely used with great success; however the presence of subgingival yeasts and resistant bacteria can be a problem in some periodontitis patients."3.73Periodontal antimicrobials--finding the right solutions. ( Aalam, A; Jorgensen, MG; Slots, J, 2005)
"After baseline clinical and microbiological monitoring, 17 adult periodontitis subjects received full mouth SRP and 14 days systemic administration of either metronidazole (250 mg, TID, n=8) or amoxicillin (500 mg, TID, n=9)."3.71Change in subgingival microbial profiles in adult periodontitis subjects receiving either systemically-administered amoxicillin or metronidazole. ( Allard, K; Feres, M; Haffajee, AD; Socransky, SS; Som, S, 2001)
" Amoxicillin was the most frequently prescribed antibiotic used for most clinical conditions apart from pericoronitis, acute ulcerative gingivitis and dry sockets where metronidazole was the drug of choice."3.70A study of therapeutic antibiotic prescribing in National Health Service general dental practice in England. ( Ireland, RS; Martin, MV; Palmer, NA; Pealing, R, 2000)
"The present investigation was performed in order to assess if the administration of metronidazole changed the composition of developing plaque in dogs, which at the start of the study were free from signs of gingivitis."3.66The effect of metronidazole on the development of plaque and gingivitis in the beagle dog. ( Heijl, L; Lindhe, J, 1979)
"As a healthcare profession, dentists have a role in ensuring the safety of prescribed medicines by reporting adverse drug reactions using the Yellow Card Scheme."2.53Metronidazole and tinnitus: A potential side effect? ( Barker, D; O'Donnell, KL, 2016)
"Metronidazole has important interactions with alcohol, disulfiram and warfarin and there are contraindications to its use."2.37Metronidazole: its use in clinical dentistry. ( Mitchell, DA, 1984)
"Periodontal diseases are common oral diseases that afflict all humans to some degree."2.37Current concepts in periodontal diseases. ( Higgins, TJ; Hunter, N; Knox, KW, 1985)
"Lemierre's syndrome is a disseminated infection which is usually caused by Fusobacterium necrophorum."1.38[Lemierre's syndrome as differential diagnosis of lung cancer]. ( Reinholdt Jensen, J; Weinreich, UM, 2012)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199024 (44.44)18.7374
1990's11 (20.37)18.2507
2000's8 (14.81)29.6817
2010's9 (16.67)24.3611
2020's2 (3.70)2.80

Authors

AuthorsStudies
Razzaq, S2
Syed, MA2
Irfan, M1
Khan, I1
Sarfraz, RM1
Shakir, R1
Ali, S1
Iqbal, Z1
Niaz, Y1
Mujtaba, SH1
Raza, SA2
Raza, S1
Hanif, S2
Mahmood, HT1
Fatima, F1
Fida, M1
Sukhia, RH1
Irfan, S1
Malik, D1
Younus, A1
Afzal, E1
Iqbal, J1
Hassan, SS1
Riaz, H1
Abid, F1
Rams, TE1
Hawley, CE1
Whitaker, EJ1
Degener, JE1
van Winkelhoff, AJ3
Pulikkotil, SJ1
Nath, S1
Rotman, A1
Michael, P1
Tykocinski, M1
O'Leary, SJ1
O'Donnell, KL1
Barker, D1
Emrani, J1
Chee, W1
Slots, J3
Reinholdt Jensen, J1
Weinreich, UM1
Amid, R1
Tabeie, MB1
Kadkhodazadeh, M1
Mehdizadeh, AR1
Youssefi, N1
Seremidi, K1
Gizani, S1
Madianos, P1
Pradeep, AR1
Kumari, M1
Priyanka, N1
Naik, SB1
Jorgensen, MG1
Aalam, A1
Kazarina, LN1
Kuzin, VB1
Ellarian, LK1
Tepaev, DV1
Notten, F1
Koek-Van Oosten, A1
Mikx, F1
Mitchell, DA1
Nuki, K1
Soskolne, WA1
Raisz, LG1
Kornman, KS1
Alander, C1
Heijl, L5
Lindhe, J5
Dahlén, G1
Möller, A1
Miotti, A1
Wei, G1
Xiao, Y1
Zhang, L1
Van den Bossche, L1
Sander, L1
Frandsen, EV1
Arnbjerg, D1
Warrer, K1
Karring, T1
Petti, S1
Renzini, G1
Walsh, TF1
Noyan, U1
Yilmaz, S1
Kuru, B1
Kadir, T1
Acar, O1
Büget, E1
Palop Larrea, V1
Pastor Navarro, C1
Collado Gil, A1
Tórtola Graner, D1
Palmer, NA1
Pealing, R1
Ireland, RS1
Martin, MV1
Feres, M1
Haffajee, AD1
Allard, K1
Som, S1
Socransky, SS1
Beertsen, W1
Piscaer, M1
Everts, V1
Pacheco, JJ1
Coelho, C1
Salazar, F1
Contreras, A1
Velazco, CH1
Bodur, A1
Bodur, H1
Bal, B1
Baloş, K1
Listgarten, MA1
Parodi, R1
Jones, JH1
Bianco, R1
Teng, YT1
Sodek, J1
McCulloch, CA1
Huynh, C1
Roch-Arveiller, M1
Meyer, J1
Giroud, JP1
Abbas, F1
Pavicic, MJ1
de Graaff, J1
Pässler, R1
Nossek, H1
Winkler, JR1
Murray, PA1
Grassi, M1
Hammerle, C1
Van Oosten, MA1
Notten, FJ1
Mikx, FH1
Llamosas Hernández, E1
Centíes Castella, R1
Britt, MR1
Pohlod, DJ1
Aziz-Gandour, IA1
Newman, HN1
Gulland, FM1
Carwardine, PC1
Higgins, TJ1
Hunter, N1
Knox, KW1
Lozdan, J1
Sheiham, A1
Pearlman, BA1
Keiser, B1
Rachanis, CC1
Meyer, R1
Stawiński, K1
Magas, A1
Wierzbicka, M1
Dean, TS1
Shinn, DL1
McFadzean, JA1
Squires, SL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Metronidazole and Amoxicillin as Adjuncts to Scaling and Root Planing for the Treatment of Type 2 Diabetic Subjects With Periodontitis: a Randomized Placebo-controlled Clinical Trial[NCT02135952]Phase 458 participants (Actual)Interventional2011-09-30Active, not recruiting
Efficacy of the Application of Moxifloxacin and Cefixime in Reduction of Inflammatory Sequelae and Complications After Mandibular Third Molar Surgery[NCT05027893]157 participants (Actual)Interventional2019-06-07Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for metronidazole and Gingivitis

ArticleYear
Metronidazole and tinnitus: A potential side effect?
    British dental journal, 2016, Mar-25, Volume: 220, Issue:6

    Topics: Anti-Infective Agents; Female; Focal Infection, Dental; Gingivitis; Humans; Metronidazole; Middle Ag

2016
Metronidazole: its use in clinical dentistry.
    Journal of clinical periodontology, 1984, Volume: 11, Issue:3

    Topics: Aggressive Periodontitis; Bacteria, Anaerobic; Drug Interactions; Gingivitis; Humans; Kinetics; Metr

1984
[Subgingival application of antibiotics: literature review].
    Revue belge de medecine dentaire, 1994, Volume: 49, Issue:2

    Topics: Administration, Topical; Anti-Bacterial Agents; Dental Scaling; Gingiva; Gingivitis; Humans; Metroni

1994
Diagnosis and management of HIV-associated periodontal lesions.
    Journal of the American Dental Association (1939), 1989, Volume: Suppl

    Topics: Chlorhexidine; Dental Care for Disabled; Dental Scaling; Gingivitis; Gingivitis, Necrotizing Ulcerat

1989
[Metronidazole in the treatment of periodontal disease].
    Practica odontologica, 1987, Volume: 8, Issue:3

    Topics: Gingivitis; Humans; Metronidazole; Periodontal Diseases

1987
Current concepts in periodontal diseases.
    The Medical journal of Australia, 1985, May-27, Volume: 142, Issue:11

    Topics: Acute Disease; Adult; Child; Chronic Disease; Dental Plaque; Gingivitis; Gingivitis, Necrotizing Ulc

1985

Trials

8 trials available for metronidazole and Gingivitis

ArticleYear
Effectiveness of metronidazole gel and mobile telephone short-message service reminders on gingivitis in orthodontic patients.
    The Angle orthodontist, 2021, 03-01, Volume: 91, Issue:2

    Topics: Dental Plaque Index; Gingivitis; Humans; Metronidazole; Oral Hygiene; Periodontal Index

2021
Effects of curcumin on crevicular levels of IL-1β and CCL28 in experimental gingivitis.
    Australian dental journal, 2015, Volume: 60, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Anti-Infective Agents; Anti-Infective Agents, Local; Ant

2015
Efficacy of chlorhexidine, metronidazole and combination gel in the treatment of gingivitis--a randomized clinical trial.
    Journal of the International Academy of Periodontology, 2012, Volume: 14, Issue:4

    Topics: Actinomyces; Administration, Topical; Adult; Chlorhexidine; Chronic Disease; Colony Count, Microbial

2012
[Influence of gel Metrogil Denta and curative toothpaste Mexidol Dent activ on indices of parodontal status and lipid peroxidation in patients with chronic generalized catarrhal gingivitis].
    Stomatologiia, 2007, Volume: 86, Issue:4

    Topics: Adolescent; Adult; Chronic Disease; Drug Therapy, Combination; Female; Gels; Gingivitis; Humans; Lip

2007
Effect of local metronidazole application on periodontal healing following guided tissue regeneration. Clinical findings.
    Journal of periodontology, 1994, Volume: 65, Issue:10

    Topics: Administration, Topical; Adult; Alveolar Bone Loss; Dental Plaque; Female; Gels; Gingival Hemorrhage

1994
A clinical and microbiological evaluation of systemic and local metronidazole delivery in adult periodontitis patients.
    Journal of clinical periodontology, 1997, Volume: 24, Issue:3

    Topics: Administration, Oral; Administration, Topical; Adult; Aggregatibacter actinomycetemcomitans; Anti-In

1997
The effects of a simplified oral hygiene regime plus supragingival irrigation with chlorhexidine or metronidazole on chronic inflammatory periodontal disease.
    Journal of clinical periodontology, 1986, Volume: 13, Issue:3

    Topics: Adult; Chlorhexidine; Chronic Disease; Dental Devices, Home Care; Dental Plaque Index; Dental Scalin

1986
The use of nitrimidazine in the treatment of acute ulcerative gingivitis. A double-blind controlled trial.
    British dental journal, 1971, Apr-06, Volume: 130, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Clinical Trials as Topic; Female; Gingivitis; Gingivitis, Necrotiz

1971

Other Studies

40 other studies available for metronidazole and Gingivitis

ArticleYear
Optimization of metronidazole SR buccal tablet for gingivitis using genetic algorithm.
    Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:6

    Topics: Adhesiveness; Administration, Buccal; Anti-Bacterial Agents; Artificial Intelligence; Delayed-Action

2021
Development and evaluation of mucoadhesive buccal tablet containing metronidazole for the treatment of periodontitis and gingivitis.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:5

    Topics: Adhesiveness; Anti-Infective Agents; Drug Development; Gingivitis; Humans; Hypromellose Derivatives;

2018
Centipeda periodontii in human periodontitis.
    Odontology, 2015, Volume: 103, Issue:3

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Biofilms; Chronic Periodontitis; DNA, Bacterial; Doxycycl

2015
Sudden sensorineural hearing loss secondary to metronidazole ototoxicity.
    The Medical journal of Australia, 2015, Sep-21, Volume: 203, Issue:6

    Topics: Adult; Anti-Infective Agents; Gingivitis; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans;

2015
Bacterial colonization of oral implants from nondental sources.
    Clinical implant dentistry and related research, 2009, Volume: 11, Issue:2

    Topics: Aggressive Periodontitis; Anti-Infective Agents; Bacteria; Bacteroides; Campylobacter rectus; Ciprof

2009
[Lemierre's syndrome as differential diagnosis of lung cancer].
    Ugeskrift for laeger, 2012, May-28, Volume: 174, Issue:22

    Topics: Abscess; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Diagnosis, Differential; Fusobacterium

2012
Local concentration of systemic amoxicillin and metronidazole in healthy and inflamed gingiva: a comparative in vivo study.
    Drug metabolism and drug interactions, 2012, May-10, Volume: 27, Issue:2

    Topics: Administration, Oral; Amoxicillin; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Drug

2012
Therapeutic management of a case of generalised aggressive periodontitis in an 8-year old child: 18-month results.
    European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2012, Volume: 13, Issue:5

    Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Alveolar Bone Loss; Amoxicillin; An

2012
Periodontal antimicrobials--finding the right solutions.
    International dental journal, 2005, Volume: 55, Issue:1

    Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents, Local; Chlorhexidine; Ciprofl

2005
Capillary agar diffusion assay for measuring metronidazole in human gingival crevice fluid.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:5

    Topics: Agar; Biological Assay; Clostridium perfringens; Diffusion; Fusobacterium; Gingival Crevicular Fluid

1982
Bone resorbing activity of gingiva from beagle dogs following metronidazole and indomethacin therapy.
    Journal of periodontal research, 1981, Volume: 16, Issue:2

    Topics: Alveolar Process; Animals; Bone Resorption; Dogs; Gingivitis; Indomethacin; Metronidazole; Periodont

1981
Effect of selective antimicrobial therapy on plaque and gingivitis in the dog.
    Journal of clinical periodontology, 1980, Volume: 7, Issue:6

    Topics: Animals; Bacteria; Clindamycin; Dental Plaque; Dogs; Drug Evaluation, Preclinical; Female; Gingiviti

1980
The effect of metronidazole on established gingivitis and plaque in beagle dogs.
    Journal of periodontology, 1982, Volume: 53, Issue:3

    Topics: Animals; Debridement; Dental Plaque; Dogs; Female; Gingivitis; Metronidazole; Time Factors; Toothbru

1982
Development of plaque and gingivitis following antibiotic therapy in dogs.
    Journal of clinical periodontology, 1982, Volume: 9, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Clindamycin; Dental Plaque; Dogs; Gingivitis; Metronidazol

1982
[Metronidazole in dentistry].
    Rivista italiana di stomatologia, 1982, Volume: 51, Issue:4

    Topics: Gingivitis; Humans; Metronidazole; Mouth Diseases; Periodontal Diseases

1982
[Effect of antimicrobial therapy on plaque and gingivitis in dogs].
    Tandlakartidningen, 1982, Jul-01, Volume: 74, Issue:13-14

    Topics: Animals; Anti-Bacterial Agents; Clindamycin; Dental Plaque; Dogs; Gingivitis; Metronidazole; Vancomy

1982
[HPLC monitoring and pharmacokinetic study of crevicular fluid concentrations after a single oral dose metronidale].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 1995, Volume: 30, Issue:1

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Female; Gingival Crevicular Fluid

1995
[A comparison between 2 different methods for calculating the percentage of anaerobic microorganisms in the subgingival microbial flora].
    Minerva stomatologica, 1994, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Bacteria, Anaerobic; Colony Count, Microbial; Evaluation Studies as Topic; Gingiv

1994
Pulsed oral irrigation in the management of inflammatory periodontal diseases.
    Dental update, 1993, Volume: 20, Issue:2

    Topics: Chlorhexidine; Dental Devices, Home Care; Gingivitis; Humans; Metronidazole; Mouthwashes; Oral Hygie

1993
[Changes in the sense of taste and metronidazole].
    Atencion primaria, 1997, Nov-30, Volume: 20, Issue:9

    Topics: Aged; Female; Gingivitis; Humans; Metronidazole; Taste

1997
A study of therapeutic antibiotic prescribing in National Health Service general dental practice in England.
    British dental journal, 2000, May-27, Volume: 188, Issue:10

    Topics: Abscess; Acute Disease; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infecti

2000
Change in subgingival microbial profiles in adult periodontitis subjects receiving either systemically-administered amoxicillin or metronidazole.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:7

    Topics: Actinomyces; Adult; Amoxicillin; Analysis of Variance; Anti-Bacterial Agents; Bacteria; Bacteroides;

2001
Generalized cervical root resorption associated with periodontal disease.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:11

    Topics: Acids; Adult; Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Amoxicillin; Anti-Bacterial

2001
Treatment of Papillon-Lefèvre syndrome periodontitis.
    Journal of clinical periodontology, 2002, Volume: 29, Issue:4

    Topics: Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Amoxicillin; Anti-Bacterial Agents; Anti-

2002
Generalized aggressive periodontitis in a prepubertal patient: a case report.
    Quintessence international (Berlin, Germany : 1985), 2001, Volume: 32, Issue:4

    Topics: Actinobacillus Infections; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Alveolar

2001
The effect of systemic antimicrobial therapy on plaque and gingivitis in dogs.
    Journal of periodontal research, 1979, Volume: 14, Issue:1

    Topics: Administration, Oral; Animals; Dental Plaque; Dogs; Gingivitis; Metronidazole; Tetracycline

1979
Healthy and diseased gingiva.
    The Practitioner, 1975, Volume: 214, Issue:1281

    Topics: Adult; Child; Chronic Disease; Dental Plaque; Diabetes Complications; Gingiva; Gingival Diseases; Gi

1975
The effect of metronidazole on the development of plaque and gingivitis in the beagle dog.
    Journal of clinical periodontology, 1979, Volume: 6, Issue:4

    Topics: Animals; Bacteria; Dental Plaque; Dogs; Gingiva; Gingivitis; Male; Metronidazole; Periodontal Index;

1979
HIV-related gingival and periodontal disorders.
    Dentistry (American Student Dental Association), 1992, Volume: 12, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Gingivitis; HIV Infections; Humans; Metronidazole; Periodonti

1992
Gingival crevicular fluid gelatinase and its relationship to periodontal disease in human subjects.
    Journal of periodontal research, 1992, Volume: 27, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Biomarkers; Chi-Square Distribution; Clinical Enzyme Tests; Colla

1992
Gingival crevicular fluid of patients with gingivitis or periodontal disease: evaluation of elastase-alpha 1 proteinase inhibitor complex.
    Journal of clinical periodontology, 1992, Volume: 19, Issue:3

    Topics: Adult; Aged; alpha 1-Antitrypsin; Anti-Infective Agents; Dental Scaling; Drug Combinations; Female;

1992
Chronic conjunctivitis caused by oral anaerobes and effectively treated with systemic metronidazole plus amoxicillin.
    Journal of clinical microbiology, 1991, Volume: 29, Issue:4

    Topics: Adult; Amoxicillin; Bacteria, Anaerobic; Bacterial Infections; Conjunctivitis, Bacterial; DNA Finger

1991
[The concentration and duration of the action of metronidazole in the gingival pocket following local application].
    Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt, 1989, Volume: 77, Issue:1

    Topics: Administration, Topical; Delayed-Action Preparations; Drug Evaluation; Drug Evaluation, Preclinical;

1989
Metronidazole concentrations in human plasma, saliva, and gingival crevice fluid after a single dose.
    Journal of dental research, 1986, Volume: 65, Issue:12

    Topics: Administration, Oral; Adult; Agar; Chromatography, High Pressure Liquid; Gingival Crevicular Fluid;

1986
Serum and crevicular fluid concentrations after a single oral dose of metronidazole.
    Journal of periodontology, 1986, Volume: 57, Issue:2

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Female; Gingival Crevicular Fluid

1986
Plasma metronidazole levels in an Indian elephant (Elephas maximus) after rectal administration.
    The Veterinary record, 1987, May-02, Volume: 120, Issue:18

    Topics: Administration, Rectal; Animals; Elephants; Female; Gingivitis; Metronidazole; Suppositories

1987
Trichomonacides: nitrimidazine v metronidazole.
    Drug and therapeutics bulletin, 1971, Dec-17, Volume: 9, Issue:26

    Topics: Female; Gingivitis; Humans; Imidazoles; Male; Metronidazole; Morpholines; Nitro Compounds; Trichomon

1971
[Clinical and bacteriologic evaluation of metronidazole in the treatment of ulcerative gingivitis and stoniatitis].
    Czasopismo stomatologiczne, 1968, Volume: 21, Issue:4

    Topics: Bacteria; Gingivitis; Gingivitis, Necrotizing Ulcerative; Humans; Metronidazole

1968
Metronidazole in the treatment of gingivitis.
    The Veterinary record, 1969, Oct-18, Volume: 85, Issue:16

    Topics: Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Gingivitis; Metronidazole

1969
Treatment of acute ulcerative (Vincent's) gingivitis.
    Drug and therapeutics bulletin, 1966, Nov-25, Volume: 4, Issue:24

    Topics: Gingivitis; Gingivitis, Necrotizing Ulcerative; Humans; Hydrogen Peroxide; Metronidazole; Penicillin

1966