metronidazole has been researched along with Gastroenteritis in 17 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Gastroenteritis: INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral gentamicin, metronidazole, and cholestyramine were given either as single agents or in various combinations to infants who still required treatment after seven days in the hospital for persistent diarrhea." | 7.67 | Use of oral gentamicin, metronidazole, and cholestyramine in the treatment of severe persistent diarrhea in infants. ( Bowie, MD; Hill, ID; Househam, KC; Mann, MD, 1986) |
| "Afebrile seizures associated with rotavirus gastroenteritis, respiratory syncytial virus bronchiolitis, influenza infection, asthma, blood transfusions, and intake of a number of drugs (including theophylline, cephalosporins, metronidazole, and acyclovir) with therapeutic drug levels are uncommonly encountered in clinical practice." | 4.85 | Common causes of uncommon seizures. ( Boustany, RM; El-Bitar, MK, 2009) |
| "Further investigation of the use of metronidazole for norovirus gastroenteritis in transplant recipients is warranted." | 4.12 | Metronidazole for treatment of norovirus in pediatric transplant recipients. ( Muller, WJ; Newman, AM; Soneji, M; Toia, J, 2022) |
| "Oral gentamicin, metronidazole, and cholestyramine were given either as single agents or in various combinations to infants who still required treatment after seven days in the hospital for persistent diarrhea." | 3.67 | Use of oral gentamicin, metronidazole, and cholestyramine in the treatment of severe persistent diarrhea in infants. ( Bowie, MD; Hill, ID; Househam, KC; Mann, MD, 1986) |
| "During the study period (6 months) upper respiratory tract infections (URTI) were the commonest illness in all groups; there were significantly more gastroenteric infections in the group given the supplement, but not the antibiotic, treatment; the children who received only the standard health service care were ill more often and for longer periods than children in the other groups." | 2.67 | The Kingston Project. III. The effects of high energy supplement and metronidazole on malnourished children rehabilitated in the community: morbidity and growth. ( Christie, CD; Dawson, S; Gernay, J; Heikens, GT; Schofield, WN, 1993) |
| "Eosinophilic gastroenteritis is a rare inflammatory disorder of the gastrointestinal tract." | 1.62 | Eosinophilic gastroenteritis in an adolescent male with history of chronic bullous disease. ( Castor, MAR; Murillo, JML; Recto, MST; Tan-Lim, CSC, 2021) |
| "Giardia infection is difficult to recognize on clinical grounds alone." | 1.34 | [The Giardia epidemic in 2004 and out-of-hours service in Bergen]. ( Damsgaard, E; Steen, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (29.41) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Soneji, M | 1 |
| Newman, AM | 1 |
| Toia, J | 1 |
| Muller, WJ | 1 |
| Brown, HL | 1 |
| Erickson, GA | 1 |
| Bhat Yellanthoor, R | 1 |
| Tan-Lim, CSC | 1 |
| Murillo, JML | 1 |
| Recto, MST | 1 |
| Castor, MAR | 1 |
| El-Bitar, MK | 1 |
| Boustany, RM | 1 |
| Serra, T | 1 |
| González de Cárdenas, M | 1 |
| Plovins, J | 1 |
| Ballesteros, A | 1 |
| Vindel, A | 1 |
| Sáez-Nieto, JA | 1 |
| Bischoff, A | 1 |
| Steen, K | 1 |
| Damsgaard, E | 1 |
| López-Cifra, H | 1 |
| Javier, M | 1 |
| Rodríguez, SV | 1 |
| Santos Ocampo, PD | 1 |
| Bowie, MD | 2 |
| Mann, MD | 2 |
| Hill, ID | 2 |
| Wilson, WH | 1 |
| Zahner, J | 1 |
| Kirchner, T | 1 |
| Ott, G | 1 |
| Schneider, W | 1 |
| Heikens, GT | 1 |
| Schofield, WN | 1 |
| Christie, CD | 1 |
| Gernay, J | 1 |
| Dawson, S | 1 |
| Hountondji, A | 1 |
| Monteiro, B | 1 |
| Savi, T | 1 |
| Diop, S | 1 |
| Donaldson, M | 1 |
| Heyneman, D | 1 |
| Dempster, R | 1 |
| Garcia, L | 1 |
| Korovina, NA | 1 |
| Levitskaia, SV | 1 |
| Bokser, GV | 1 |
| Spirina, TS | 1 |
| Taranenko, LA | 1 |
| Safonova, TB | 1 |
| Househam, KC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics of Antimicrobials and Carriage of Antimicrobial Resistance Amongst Hospitalised Children With Severe Acute Malnutrition[NCT02746276] | Phase 2 | 81 participants (Actual) | Interventional | 2016-04-01 | Active, not recruiting | ||
| First Line Antimicrobials in Children With Complicated Severe Acute Malnutrition[NCT03174236] | Phase 3 | 2,000 participants (Anticipated) | Interventional | 2017-09-04 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for metronidazole and Gastroenteritis
| Article | Year |
|---|---|
Common causes of uncommon seizures.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antiviral Agents; Asthma; Brain; Bronchiolitis; Child; | 2009 |
2 trials available for metronidazole and Gastroenteritis
| Article | Year |
|---|---|
The Kingston Project. III. The effects of high energy supplement and metronidazole on malnourished children rehabilitated in the community: morbidity and growth.
Topics: Child, Preschool; Data Interpretation, Statistical; Food, Fortified; Gastroenteritis; Growth; Humans | 1993 |
The Kingston Project. III. The effects of high energy supplement and metronidazole on malnourished children rehabilitated in the community: morbidity and growth.
Topics: Child, Preschool; Data Interpretation, Statistical; Food, Fortified; Gastroenteritis; Growth; Humans | 1993 |
The Kingston Project. III. The effects of high energy supplement and metronidazole on malnourished children rehabilitated in the community: morbidity and growth.
Topics: Child, Preschool; Data Interpretation, Statistical; Food, Fortified; Gastroenteritis; Growth; Humans | 1993 |
The Kingston Project. III. The effects of high energy supplement and metronidazole on malnourished children rehabilitated in the community: morbidity and growth.
Topics: Child, Preschool; Data Interpretation, Statistical; Food, Fortified; Gastroenteritis; Growth; Humans | 1993 |
[Comparative evaluation of the effectiveness of the treatment of gastroduodenal Campylobacter infection in children].
Topics: Anti-Infective Agents; Campylobacter Infections; Duodenitis; Furazolidone; Gastroenteritis; Humans; | 1991 |
14 other studies available for metronidazole and Gastroenteritis
| Article | Year |
|---|---|
Metronidazole for treatment of norovirus in pediatric transplant recipients.
Topics: Child; Chronic Disease; Diarrhea; Gastroenteritis; Humans; Metronidazole; Norovirus; Retrospective S | 2022 |
Clostridium difficile infection after antibiotic use.
Topics: Adult; Age Factors; Anti-Bacterial Agents; Antimicrobial Stewardship; Cefpodoxime; Ceftizoxime; Clos | 2020 |
Acute gastroenteritis due to
Topics: Acute Disease; Adolescent; Antiprotozoal Agents; Blastocystis hominis; Blastocystis Infections; Fece | 2020 |
Eosinophilic gastroenteritis in an adolescent male with history of chronic bullous disease.
Topics: Abdominal Pain; Adolescent; Anti-Infective Agents; Appendicitis; Diarrhea; Enteritis; Eosinophilia; | 2021 |
[Three cases of Yersinia pseudotuberculosis gastrointestinal infection having no apparent epidemiological relationship, caused by identical strains].
Topics: Abdominal Pain; Adult; Amoxicillin; Bacterial Typing Techniques; Child; Diarrhea; Doxycycline; Drug | 2005 |
[Gastrointestinal infections. Economize with antibiotics!].
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Diarrhea; Gastroenteritis; Humans; Metronidazole | 2005 |
[The Giardia epidemic in 2004 and out-of-hours service in Bergen].
Topics: Adult; Animals; Anti-Infective Agents; Antiprotozoal Agents; Child; Disease Outbreaks; Emergency Med | 2007 |
The efficacy of metronidazole in the treatment of giardiasis.
Topics: Child; Child, Preschool; Chronic Disease; Diarrhea; Feces; Female; Follow-Up Studies; Gastroenteriti | 1982 |
The bowel cocktail.
Topics: Cholestyramine Resin; Diarrhea; Electrolytes; Fluid Therapy; Gastroenteritis; Gentamicins; Glucose; | 1981 |
Eczema responsive to treatment for Helicobacter pylori.
Topics: Anti-Bacterial Agents; Bismuth; Drug Therapy, Combination; Eczema; Gastroenteritis; Helicobacter Inf | 1995 |
[Immunoproliferative small intestinal disease (IPSID): an unusual form of gastrointestinal lymphoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Diagnosis, Differential; Female; Gastroenteri | 1994 |
[Place of salmonellosis in gastroenteritis in Cotonou].
Topics: Adolescent; Adult; Age Factors; Ampicillin; Benin; Chloramphenicol; Female; Gastroenteritis; Humans; | 1979 |
Epizootic of fatal amebiasis among exhibited snakes: epidemiologic, pathologic, and chemotherapeutic considerations.
Topics: Amebiasis; Animals; Animals, Zoo; Emetine; Entamoebiasis; Enteritis; Gastroenteritis; Inflammation; | 1975 |
Use of oral gentamicin, metronidazole, and cholestyramine in the treatment of severe persistent diarrhea in infants.
Topics: Cholestyramine Resin; Diarrhea; Drug Interactions; Drug Therapy, Combination; Gastroenteritis; Genta | 1986 |