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metronidazole and Gastroduodenal Ulcer

metronidazole has been researched along with Gastroduodenal Ulcer in 255 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"Inpatients with peptic ulcer complications who were not able to take oral medicine were randomly assigned to three groups: triple therapy (esomeprazole, levofloxacin, metronidazole) and dual therapy (esomeprazole, levofloxacin/metronidazole) for 7 days."9.69Intravenous metronidazole-, levofloxacin-containing triple therapy for treating patients with Helicobacter pylori-related active peptic ulcer complications: A pilot study. ( Chen, J; Gui, Q; Liang, X; Lu, H; Su, W; Yu, D; Zhang, W; Zhu, C, 2023)
"Levofloxacin-tinidazole-based triple therapy was highly effective and safe as a first-line regimen in Indian patients with gastroduodenal ulcer disease associated with H."9.17Safety and efficacy of 1-week levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori-related peptic ulcer disease in Kashmir, India. ( Gulzar, GM; Javid, G; Khan, BA; Khan, MA; Saif, R; Shah, A; Shoukat, A; Sodhi, JS; Teli, F; Yattoo, GN; Zargar, SA, 2013)
"Patients with proven peptic ulcer or duodenitis were randomized into three groups: OAB-M-F; metronidazole (M) (500 mg bid) for the first 5 days, followed by furazolidone (F) (200 mg bid) for the second 5 days; OAC-P; clarithromycin (C) (500 mg bid) for 10 days; and OAB-C-F; clarithromycin (500 mg bid) for the first 5 days and furazolidone (200 mg bid) for the second 5 days."9.14Sequential metronidazole-furazolidone or clarithromycin-furazolidone compared to clarithromycin-based quadruple regimens for the eradication of Helicobacter pylori in peptic ulcer disease: a double-blind randomized controlled trial. ( Agah, S; Ebrahimi-Dariani, N; Khatibian, M; Malekzadeh, R; Massarrat, S; Mikaeli, J; Pourshams, A; Riahizadeh, S; Sotoudehmanesh, R; Vahedi, H; Zendehdel, N, 2010)
" pylori-positive peptic ulcer were randomly divided into two groups, and accepted triple therapy with omeprazole 20 mg, amoxicillin 1000 mg and either clarithromycin 500 mg (OAC group, n = 58) or metronidazole 400 mg (OAM group, n = 45)."9.11Efficacy of omeprazole and amoxicillin with either clarithromycin or metronidazole on eradication of Helicobacter pylori in Chinese peptic ulcer patients. ( Cao, DZ; Fu, XL; Hu, JM; Ou, XL; Su, H; Sun, WH; Sun, YL; Yu, Q; Yu, T; Zhu, F, 2005)
"To compare the short-term (7-day) safety and efficacy of two triple-therapy regimens using pantoprazole with those of two dual-therapy regimens (one with pantoprazole and one without), for Helicobacter pylori eradication in patients with peptic ulcer disease."9.10Eradication of Helicobacter pylori by 7-day triple-therapy regimens combining pantoprazole with clarithromycin, metronidazole, or amoxicillin in patients with peptic ulcer disease: results of two double-blind, randomized studies. ( Bochenek, WJ; Davis, KD; El-Zimaity, HM; Fraga, PD; Graham, DY; Mack, ME; Osato, MS; Peters, S; Wang, W, 2003)
"Rabeprazole is a new fast acting proton pump inhibitor that has recently been proven to be effective in the treatment of peptic ulceration and reflux esophagitis."9.08Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration. ( Atherton, JC; Cockayne, A; Hawkey, CJ; Jenkins, D; Knifton, A; Stack, WA; Thirlwell, D, 1998)
"In this prospective controlled study conducted in a single center, 78 symptomatic peptic ulcer patients were treated for 4 wk with omeprazole 40 mg o."9.08Does pretreatment with omeprazole decrease the chance of eradication of Helicobacter pylori in peptic ulcer patients? ( Anania, MC; Annibale, B; D'Ambra, G; Delle Fave, G; Iannoni, C; Luzzi, I; Marcheggiano, A; Marignani, M; Paoletti, M, 1997)
"A total of 152 patients with recurrent peptic ulcer disease were treated with bismuth subnitrate, oxytetracycline and metronidazole."9.07Helicobacter pylori eradication with bismuth subnitrate, oxytetracycline and metronidazole in patients with peptic ulcer disease. ( Berstad, A; Berstad, K; Hausken, T; Hundal, O; Weberg, R; Wilhelmsen, I, 1994)
"Two 4-week triple-therapy treatment regimens, metronidazole+tetracycline+bismuth subcitrate and omeprazole+amoxycillin+bismuth subcitrate, were compared in a randomly allocated double-blind trial for their efficacy in eradicating Helicobacter pylori from the gastric mucosa of patients with gastritis and/or peptic ulcer disease."9.07Pharmacological effects of metronidazole+tetracycline+bismuth subcitrate versus omeprazole+amoxycillin+bismuth subcitrate in Helicobacter pylori-related gastritis and peptic ulcer disease. ( Hahm, JS; Kim, HJ; Park, KN, 1994)
" pylori infection in active peptic ulcer in Korea (30 mg of lansoprazole, 250 mg of clarithromycin, and 400 mg of metronidazole, all twice daily)."7.70One-week triple therapy with lansoprazole, clarithromycin, and metronidazole to cure Helicobacter pylori infection in peptic ulcer disease in Korea. ( El-Zimaity, HM; Graham, DY; Kim, JG; Osato, MS; Perng, CL, 1998)
"Inpatients with peptic ulcer complications who were not able to take oral medicine were randomly assigned to three groups: triple therapy (esomeprazole, levofloxacin, metronidazole) and dual therapy (esomeprazole, levofloxacin/metronidazole) for 7 days."5.69Intravenous metronidazole-, levofloxacin-containing triple therapy for treating patients with Helicobacter pylori-related active peptic ulcer complications: A pilot study. ( Chen, J; Gui, Q; Liang, X; Lu, H; Su, W; Yu, D; Zhang, W; Zhu, C, 2023)
"Pre-treatment metronidazole susceptible H pylori were significantly more likely to respond to the triple therapy used than those with the metronidazole resistant ones (14 of 15 v five of 10) (p = 0."5.29Prevalence of metronidazole resistant Helicobacter pylori strains among Chinese peptic ulcer disease patients and normal controls in Hong Kong. ( Ching, CK; Lai, CL; Lai, KC; Lam, SK; Leung, KP; Wong, BC; Yung, RW, 1996)
"Levofloxacin-tinidazole-based triple therapy was highly effective and safe as a first-line regimen in Indian patients with gastroduodenal ulcer disease associated with H."5.17Safety and efficacy of 1-week levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori-related peptic ulcer disease in Kashmir, India. ( Gulzar, GM; Javid, G; Khan, BA; Khan, MA; Saif, R; Shah, A; Shoukat, A; Sodhi, JS; Teli, F; Yattoo, GN; Zargar, SA, 2013)
"Patients with proven peptic ulcer or duodenitis were randomized into three groups: OAB-M-F; metronidazole (M) (500 mg bid) for the first 5 days, followed by furazolidone (F) (200 mg bid) for the second 5 days; OAC-P; clarithromycin (C) (500 mg bid) for 10 days; and OAB-C-F; clarithromycin (500 mg bid) for the first 5 days and furazolidone (200 mg bid) for the second 5 days."5.14Sequential metronidazole-furazolidone or clarithromycin-furazolidone compared to clarithromycin-based quadruple regimens for the eradication of Helicobacter pylori in peptic ulcer disease: a double-blind randomized controlled trial. ( Agah, S; Ebrahimi-Dariani, N; Khatibian, M; Malekzadeh, R; Massarrat, S; Mikaeli, J; Pourshams, A; Riahizadeh, S; Sotoudehmanesh, R; Vahedi, H; Zendehdel, N, 2010)
" pylori-positive peptic ulcer were randomly divided into two groups, and accepted triple therapy with omeprazole 20 mg, amoxicillin 1000 mg and either clarithromycin 500 mg (OAC group, n = 58) or metronidazole 400 mg (OAM group, n = 45)."5.11Efficacy of omeprazole and amoxicillin with either clarithromycin or metronidazole on eradication of Helicobacter pylori in Chinese peptic ulcer patients. ( Cao, DZ; Fu, XL; Hu, JM; Ou, XL; Su, H; Sun, WH; Sun, YL; Yu, Q; Yu, T; Zhu, F, 2005)
"The purpose of this study was to compare the efficacy of tinidazole- versus clarithromycin-based triple regimens for eradication of Helicobacter pylori in North Indian patients of peptic ulcer disease, and to correlate the outcome with in vitro antibiotic susceptibility."5.11Use of imidazole-based eradication regimens for Helicobacter pylori should be abandoned in North India regardless of in vitro antibiotic sensitivity. ( Ahuja, V; Bal, C; Bhatia, V; Das, B; Sharma, MP, 2004)
" pylori positive peptic ulcer disease or functional dyspepsia were treated with two-day quadruple therapy (lansoprazole 30 mg twice daily, and colloidal bismuth subcitrate 120 mg, tetracycline 250 mg and metronidazole 250 mg, all eight times a day)."5.11The influence of pretreatment on cure rates of Helicobacter pylori eradication. ( de Boer, WA; Jansen, JB; Janssen, MJ; Laheij, RJ, 2004)
"To compare the short-term (7-day) safety and efficacy of two triple-therapy regimens using pantoprazole with those of two dual-therapy regimens (one with pantoprazole and one without), for Helicobacter pylori eradication in patients with peptic ulcer disease."5.10Eradication of Helicobacter pylori by 7-day triple-therapy regimens combining pantoprazole with clarithromycin, metronidazole, or amoxicillin in patients with peptic ulcer disease: results of two double-blind, randomized studies. ( Bochenek, WJ; Davis, KD; El-Zimaity, HM; Fraga, PD; Graham, DY; Mack, ME; Osato, MS; Peters, S; Wang, W, 2003)
"Clinical efficiency and safety of Epigam containing antibodies to histamine in ultralow doses were studied during the therapy of patients with exacerbation of peptic ulcer disease of the stomach and duodenum associated with Helicobacter pylori infection."5.10Clinical efficiency of Epigam in patients with exacerbation of peptic ulcer disease of the stomach and duodenum. ( Bakumov, PA; Dugina, YL; Epstein, OI; Sergeeva, SA; Shchepotkin, IV, 2003)
"We conducted a prospective, uncontrolled study of a consecutive series of 21 peptic ulcer patients with failure of 1-week lansoprazole, amoxicillin, and clarithromycin."5.09Quadruple therapy is effective for eradicating Helicobacter pylori after failure of triple proton-pump inhibitor-based therapy: a detailed, prospective analysis of 21 consecutive cases. ( Ducóns, JA; Ferrero, M; García Cabezudo, J; Gomollón, F; Guirao, R; Montoro, M; Simón, MA, 1999)
"Ninety patients with established peptic ulcer and NUD (with previously proven ulcer) were randomly assigned to receive either bismuth-subcitrate, amoxycillin and metrnidazole (BAM) or lansoprasole, clarithromycine and metronidazole (LCM) for 7 days."5.09The effect of culture results for Helicobacter pylori on the choice of treatment following failure of initial eradication. ( Avidan, B; Bar-Meir, S; Keller, N; Melzer, E, 2001)
"A total of 122 consecutive patients with peptic ulcer and Helicobacter pylori infection were treated with omeprazole 20 mg b."5.09Modified seven-day, quadruple therapy as a first line Helicobacter pylori treatment. ( Brullet, E; Calvet, X; Campo, R; Garcia, N; Gené, E; Sanfeliu, I, 2001)
"Lansoprazole-based quadruple therapy achieves a very high cure rate in an unselected population of either peptic ulcer patients or those with H."5.08Lansoprazole quadruple therapy is effective in curing Helicobacter pylori infection. ( Bolin, TD; Engelman, JL; Korman, MG; Nicholson, FB, 1998)
"Rabeprazole is a new fast acting proton pump inhibitor that has recently been proven to be effective in the treatment of peptic ulceration and reflux esophagitis."5.08Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration. ( Atherton, JC; Cockayne, A; Hawkey, CJ; Jenkins, D; Knifton, A; Stack, WA; Thirlwell, D, 1998)
" pylori-positive peptic ulcer received lansoprazole 30 mg twice daily in combination with metronidazole 400 mg twice daily and clarithromycin 250 mg twice daily for 5 days."5.08Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough? ( Cunnane, K; Kelly, S; Laundon, J; McLoughlin, R; O'Connor, HJ, 1998)
" pylori-positive peptic ulcer received omeprazole 20 mg twice daily in combination with metronidazole 400 mg twice daily and clarithromycin 500 mg twice daily for seven days."5.08One week triple therapy for Helicobacter pylori: does high-dose clarithromycin confer additional benefit? ( Bhutta, AS; Bindel, H; Cunnane, K; Loane, J; O'Connor, HJ, 1997)
" pylori infection and peptic ulcer disease (n = 64) or functional dyspepsia (n = 16), with similar demographic and clinical characteristics, were treated for 1 week with either omeprazole 20 mg once in the morning and clarithromycin 250 mg and metronidazole 400 mg twice daily (OCM; n = 40) or with omeprazole 20 mg once in the morning and clarithromycin 250 mg and tetracycline 500 mg twice daily (OCT; n = 40)."5.08One-week low-dose triple therapy for the eradication of Helicobacter pylori infection. ( Becker, T; Börsch, G; Labenz, J; Rühl, GH; Sollböhmer, M; Stolte, M; Tillenburg, B, 1995)
"Eradication of Helicobacter pylori from the stomach by triple therapy with bismuth, tetracycline, and metronidazole cures peptic ulcer disease."5.08Effect of acid suppression on efficacy of treatment for Helicobacter pylori infection. ( de Boer, W; Driessen, W; Jansz, A; Tytgat, G, 1995)
"Eighty-two patients with severe peptic ulcer disease and concurrent Helicobacter pylori infection were treated with a two week regimen of omeprazole (40 mg once daily), amoxycillin (750 mg t."5.08Immediate repeat course of amoxycillin, metronidazole and omeprazole to eradicate Helicobacter pylori. ( Jönsson, KA; Sörberg, M; Ström, M, 1997)
"Patients with active HP infection and peptic ulcer, a history of peptic ulcer, or nonulcer dyspepsia were randomized to either lansoprazole 30 mg b."5.08Bismuth subsalicylate instead of metronidazole with lansoprazole and clarithromycin for Helicobacter pylori infection: a randomized trial. ( Barnett, JL; Chey, WD; DelValle, J; Elta, GH; Fisher, L; Hasler, WL; Nostrant, T; Scheiman, JM, 1997)
"In this prospective controlled study conducted in a single center, 78 symptomatic peptic ulcer patients were treated for 4 wk with omeprazole 40 mg o."5.08Does pretreatment with omeprazole decrease the chance of eradication of Helicobacter pylori in peptic ulcer patients? ( Anania, MC; Annibale, B; D'Ambra, G; Delle Fave, G; Iannoni, C; Luzzi, I; Marcheggiano, A; Marignani, M; Paoletti, M, 1997)
"Two 4-week triple-therapy treatment regimens, metronidazole+tetracycline+bismuth subcitrate and omeprazole+amoxycillin+bismuth subcitrate, were compared in a randomly allocated double-blind trial for their efficacy in eradicating Helicobacter pylori from the gastric mucosa of patients with gastritis and/or peptic ulcer disease."5.07Pharmacological effects of metronidazole+tetracycline+bismuth subcitrate versus omeprazole+amoxycillin+bismuth subcitrate in Helicobacter pylori-related gastritis and peptic ulcer disease. ( Hahm, JS; Kim, HJ; Park, KN, 1994)
"A total of 152 patients with recurrent peptic ulcer disease were treated with bismuth subnitrate, oxytetracycline and metronidazole."5.07Helicobacter pylori eradication with bismuth subnitrate, oxytetracycline and metronidazole in patients with peptic ulcer disease. ( Berstad, A; Berstad, K; Hausken, T; Hundal, O; Weberg, R; Wilhelmsen, I, 1994)
"Thirty-one patients with major upper gastrointestinal bleeding from peptic ulcer were studied; 17 received triple therapy and 14 ranitidine alone."5.07Treatment of Helicobacter pylori reduces the rate of rebleeding in peptic ulcer disease. ( Graham, DY; Hepps, KS; Lew, GM; Ramirez, FC; Saeed, ZA, 1993)
" pylori eradication is achieved; (5) the eradication rates seem to be higher in peptic ulcer than in nonulcer dyspepsia; (6) in areas where the prevalence of metronidazole resistance is high, triple therapy including a PPI, clarithromycin, and amoxicillin is the best option, and (7) quadruple therapy (PPI, bismuth, tetracycline, and metronidazole) is the recommended second-line therapy after PPI-clarithromycin-amoxicillin failure, although replacing the PPI and the bismuth compound by ranitidine bismuth citrate achieves also good results."4.81Helicobacter pylori therapy: first-line options and rescue regimen. ( Gisbert, JP; Pajares, JM, 2001)
" Metronidazole resistance in peptic ulcer patients was significantly higher."3.83A high-throughput multiplex genetic detection system for Helicobacter pylori identification, virulence and resistance analysis. ( Bian, H; Fang, Y; Hu, B; Kong, M; Miao, Y; Olszewski, MA; Wang, S; Wu, Y; Xu, L; Yang, C; Zhang, Y; Zhao, F; Zhao, H, 2016)
" pylori culture positive dyspeptic patients (64 patients with peptic ulcer, PU) completed a 2-week treatment with omeprazole, amoxicillin and metronidazole and underwent endoscopy again 6-8 weeks after the end of therapy."3.78Factors modulating the outcome of treatment for the eradication of Helicobacter pylori infection. ( Figura, N; Giordano, N; Langone, F; Moretti, E; Vaglio, L; Vernillo, R; Vindigni, C, 2012)
" pylori eradication in peptic ulcer patients treated with pantoprazole in Polish Caucasian peptic ulcer patients administered pantoprazole, amoxicillin, and metronidazole."3.76Effects of CYP2C19, MDR1, and interleukin 1-B gene variants on the eradication rate of Helicobacter pylori infection by triple therapy with pantoprazole, amoxicillin, and metronidazole. ( Bielicki, D; Droździk, M; Gawrońska-Szklarz, B; Kurzawski, M; Marlicz, W; Siuda, A, 2010)
"Patients with peptic ulcer who failed with first-line triple eradication therapy containing clarithromycin received quadruple therapy with omeprazole (20 mg, twice daily), amoxicillin (750 mg, twice daily), metronidazole (500 mg, twice daily) and ecabet sodium (1000 mg, twice daily) for 14 days."3.76Quadruple therapy with ecabet sodium, omeprazole, amoxicillin and metronidazole is effective for eradication of Helicobacter pylori after failure of first-line therapy (KDOG0201 Study). ( Ae, T; Azuma, M; Higuchi, K; Ishido, K; Katada, C; Koizumi, W; Nakatani, K; Nakayama, N; Nishimura, K; Saigenji, K; Sasaki, T; Tanabe, S, 2010)
" pylori eradication in peptic ulcer patients treated with pantoprazole."3.73Effect of CYP2C19*17 gene variant on Helicobacter pylori eradication in peptic ulcer patients. ( Droździk, M; Gawrońska-Szklarz, B; Kurzawski, M; Siuda, A; Starzyńska, T; Wrześniewska, J, 2006)
" pylori isolates from patients with peptic ulcer disease reporting for clinical management to the Post Graduate Institute of Medical Education and Research, Chandigarh; All India Institute of Medical Sciences, New Delhi; Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow; Deccan College of Medical Sciences and Allied Hospitals, Hyderabad; and hospitals in Chennai in collaboration with the Dr ALM Post Graduate Institute of Basic Medical Sciences were analyzed for their levels of antibiotic susceptibility to metronidazole, clarithromycin, amoxycillin, ciprofloxacin and tetracycline."3.72Geographical difference in antimicrobial resistance pattern of Helicobacter pylori clinical isolates from Indian patients: Multicentric study. ( Ayyagari, A; Bhasin, D; Das, BK; Dharmalingam, S; Habibullah, CM; Khan, AA; Naik, SR; Rajasambandam, P; Ramathilagam, B; Rao, UA; Ray, P; Sharma, MP; Thyagarajan, SP, 2003)
"One hundred eight patients with cultured H pylori-positive gastritis or peptic ulcer were treated with three regimens: quadruple treatment without proton pump inhibitors (n = 25), dual treatment with omeprazole and amoxicillin (INN, amoxicilline) (n = 26), and triple treatment with omeprazole, amoxicillin, and clarithromycin (n = 57)."3.70CYP2C19 genotype-related efficacy of omeprazole for the treatment of infection caused by Helicobacter pylori. ( Aoyama, N; Kasuga, M; Kita, T; Komada, F; Okumura, K; Shirakawa, K; Tanigawara, Y, 1999)
" pylori infection in active peptic ulcer in Korea (30 mg of lansoprazole, 250 mg of clarithromycin, and 400 mg of metronidazole, all twice daily)."3.70One-week triple therapy with lansoprazole, clarithromycin, and metronidazole to cure Helicobacter pylori infection in peptic ulcer disease in Korea. ( El-Zimaity, HM; Graham, DY; Kim, JG; Osato, MS; Perng, CL, 1998)
"The prevalence of metronidazole and clarithromycin resistance of Helicobacter pylori strains under different growth conditions (microaerophilic or anaerobic preincubation) was tested in 56 patients suffering from gastritis and peptic ulcer."3.70Metronidazole and clarithromycin susceptibility and the subtypes of vacA of Helicobacter pylori isolates in Estonia. ( Kasenõmm, P; Kolk, H; Lõivukene, K; Maaroos, HI; Mikelsaar, M; Ustav, M, 2000)
"Fifty-two patients with peptic ulcer disease and antral biopsies containing Helicobacter pylori sensitive to metronidazole were given a 7-day course of treatment: omeprazole 20 mg b."3.69A one-week quadruple eradication regimen for Helicobacter pylori in routine clinical practice. ( Scott, BB; Vautier, G, 1997)
" pylori-positive patients with recurrent peptic ulcer diseases, 29 of whom were given triple therapy (amoxycillin and metronidazole for 1 week and plaunotol for 4 weeks)."3.69Evaluation of a new bismuth-free triple therapy in nude mice and humans. ( Karita, M; Nakazawa, T; Okita, K; Sugiyama, T; Tsuda, M, 1995)
" pylori infection and peptic ulcer disease or functional dyspepsia were treated with either omeprazole 20 mg b."3.69One-week triple therapy with omeprazole, amoxycillin and either clarithromycin or metronidazole for cure of Helicobacter pylori infection. ( Becker, T; Börsch, G; Labenz, J; Peitz, U; Stolte, M; Tillenburg, B, 1996)
" Thirty-two consecutive patients (suffering from either peptic ulcer or nonulcer dyspepsia) with Helicobacter pylori infection received omeprazole (40 mg) + bismuth subcitrate (240 mg x 4) + amoxicillin suspension (2000 mg x 4) + metronidazole (500 mg x 4), for only one day."3.68One-day therapy for treatment of Helicobacter pylori infection. ( Barbara, L; Biasco, G; Corinaldesi, R; Gasperoni, S; Paparo, GF; Ricci-Maccarini, M; Stanghellini, V; Tucci, A; Varoli, O, 1993)
" The incidence of adverse events with the use of triple, four-component and hybrid ET regimens was 15; 18."2.87Evaluation of the efficacy and safety of the hybrid scheme for eradication therapy of Helicobacter pylori infection. ( Andreev, DN; Dicheva, DT; Maiev, IV; Partzvania-Vinogradova, EV; Yurenev, GL, 2018)
"Levodopa was prescribed for groups 1 and 3."2.72Does delayed gastric emptying shorten the H pylori eradication period? A double blind clinical trial. ( Alizadeh, M; Arj, A; Bagheri-Lankarani, K; Bahri-Najafi, R; Dehbashi, N; Emami, MH; Esmaeili, A; Fattahi, MR; Geramizadeh, B; Kaviani, MJ; Saberfiroozi, MM; Taghavi, AR, 2006)
"Peptic ulcer was found in 6."2.71Does the 'test-and-treat' strategy work in primary health care for management of uninvestigated dyspepsia? A prospective two-year follow-up study of 1552 patients. ( Färkkilä, M; Sarna, S; Sipponen, P; Valtonen, V, 2004)
"Rabeprazole is a new proton pump inhibitor, which has been reported to induce a faster acid suppression than other drugs of the same category."2.71Comparable Helicobacter pylori eradication rates obtained with 4- and 7-day rabeprazole-based triple therapy: a preliminary study. ( Bilardi, C; Dulbecco, P; Gambaro, C; Iiritano, E; Mansia, C; Savarino, V; Usai, P; Vigneri, S; Zentilin, P, 2003)
"Pretreatment with omeprazole did not reduce the cure rate for this new quadruple therapy."2.69A new quadruple therapy for the eradication of Helicobacter pylori. Effect of pretreatment with omeprazole on the cure rate. ( Maeda, K; Nishimura, H; Oda, K; Ohkuma, K; Okabe, N; Okada, M; Oki, K; Seo, M; Shirotani, T, 1998)
"pylori recurrence rate."2.69[Recurrence rate of H. pylori after successful eradication and second eradication therapy after initial failure of treatment]. ( Iijima, K; Kato, K; Ohara, S; Sekine, H, 1999)
" Pre-treatment with a proton pump inhibitor, higher doses or more frequent dosing may be necessary to increase the cure rate of short duration regimens."2.69Comparison of two 3-day Helicobacter pylori eradication regimens with a standard 1-week regimen. ( Cross, R; Grimley, CE; Illing, RC; Lismore, JR; Loft, DE; Nwokolo, CU; O'sullivan, M; Penny, A; Shebani, M, 1999)
" The aim of this study was to determine the optimal dose and duration of lansoprazole (LA) administration in combination with amoxicillin (AMPC) and metronidazole (MNZ)."2.69Eradication of Helicobacter pylori using 30 mg or 60 mg lansoprazole combined with amoxicillin and metronidazole: one and two weeks of a new triple therapy. ( Asaka, M; Ishizuka, J; Kagaya, H; Katagiri, M; Kato, M; Komatsu, Y; Kudo, M; Kudo, T; Nishikawa, K; Sugiyama, T; Sukegawa, M; Takeda, H; Toyota, J, 1999)
"Lansoprazole has superior anti-Helicobacter activity in vitro and possibly also in vivo; therefore we investigated quadruple therapy with lansoprazole."2.68Effectiveness of quadruple therapy using lansoprazole, instead of omeprazole, in curing Helicobacter pylori infection. ( de Boer, WA; Driessen, WM; Lai, JY; Schneeberger, PM; van de Wouw, BA; van Etten, RJ, 1996)
" pylori than ranitidine when given with amoxicillin plus metronidazole for the treatment of duodenal ulcer, as both early reinfection and ulcer recurrence are diminished."2.68Ranitidine versus colloidal bismuth subcitrate in combination with amoxicillin and metronidazole for eradicating Helicobacter pylori in patients with duodenal ulcer. ( Blanco, M; Carpintero, P; Pajares, JM, 1997)
"Some recent studies have reported high recurrence rates after apparent cure."2.68Long-term follow-up after cure of Helicobacter pylori infection with 4 days of quadruple therapy. ( De Boer, WA; Driessen, WM; Geuskens, LM; Lai, JY, 1996)
"Metronidazole resistance was induced in 8 out of 16 with a sensitive strain."2.68One-day intensified lansoprazole-quadruple therapy for cure of Helicobacter pylori infection. ( de Boer, WA; Ouwehand, ME; Schade, RW; Schneeberger, PM; Tytgat, GN; van Etten, RJ; van Unnik, AJ, 1997)
"Most gastroduodenal ulcers are due to HP infection."2.52[What is new in treating Helicobacter pylori infection?]. ( Fischbach, W; Glocker, E; Malfertheiner, P; Scherübl, H, 2015)
"All patients with peptic ulcer disease, gastric cancer, and MALT lymphoma should be tested for Hp."2.47Diagnosis and treatment of Helicobacter pylori infection. ( Bytzer, P; Dahlerup, JF; Eriksen, JR; Jarbøl, DE; Rosenstock, S; Wildt, S, 2011)
"Peptic ulcer is now recognized as a chronic gastric infectious disease."2.40[Helicobacter pylori infection and ulcer]. ( Blum, AL; Malfertheiner, P, 1998)
"Eradication rate of Helicobacter pylori in dual therapy (omeprazole/amoxicillin) are reported in the range of 28-91%, side effect such as loose stool and skin reaction are reported 3."2.40[Eradication rate and side effect from a point of view of Helicobacter pylori eradication of peptic ulcer disease in dual therapy or new triple therapy]. ( Iwasaki, A, 1999)
"pylori infection decreases recurrence rates and facilitates healing, antibiotic therapy is indicated for all H."2.39Consensus conference. Medical treatment of peptic ulcer disease. Practice guidelines. Practice Parameters Committee of the American College of Gastroenterology. ( Soll, AH, 1996)
"14C-urea breath test was the "gold standard" and the specificity of the biopsy urease test in diagnosing H."2.39Bismuth therapy for Helicobacter pylori infection. A review of five years experience at a university hospital in Norway. ( Bergseth, M; Berstad, A; Berstad, K; Hundal, O; Olafsson, S; Tefera, S; Wilhelmsen, I, 1996)
"pylori eradication is early gastric cancer in addition to the previous indications of peptic ulcer including scar and Marginal zone B cell lymphoma (MALT type)."1.35[Diagnosis and treatment guidelines for Helicobacter pylori infection in Korea]. ( Choe, YH; Chung, IS; Kim, HS; Kim, JI; Kim, JJ; Kim, N, 2009)
"Chronic urticaria is a persistent urticaria lasting longer than 6 weeks, affecting 20% of the general population."1.35Helicobacter pylori infection in patients with chronic urticaria: correlation with pathologic findings in gastric biopsies. ( Abdou, AG; Elnaidany, NF; Elshayeb, EI; Farag, AG, 2009)
"The influence of synthetic drugs prescribed for peptic ulcer on the pharmacokinetic fate of glycyrrhizin (GL) from Shaoyao-Gancao-tang (SGT, a traditional Chinese formulation, Shakuyaku-Kanzo-to in Japanese) was investigated in rats."1.31The influence of commonly prescribed synthetic drugs for peptic ulcer on the pharmacokinetic fate of glycyrrhizin from Shaoyao-Gancao-tang. ( Akao, T; He, JX; Nishino, T; Tani, T, 2001)
"pylori induces de novo GERD symptoms in ulcer patients."1.31Symptomatic benefit 1-3 years after H. pylori eradication in ulcer patients: impact of gastroesophageal reflux disease. ( Dickson, A; El-Nujumi, A; El-Omar, E; Kelman, A; McColl, KE, 2000)
"Metronidazole is an important component in most eradication regimens."1.31Metronidazole-resistant Helicobacter pylori in an urban Asian population. ( Fock, KM; Khor, CJ; Ng, TM; Tan, AL; Teo, EK, 2000)
"Clarithromycin resistance was more common in older patients (P<0."1.31Factors affecting the variation in antibiotic resistance of Helicobacter pylori over a 3-year period. ( Ducóns, JA; Ferrero, M; Gomollón, F; Santolaria, S; Sicilia, B; Sierra, E, 2000)
"1 year after drug therapy the recurrence of CDU is revealed in 16."1.31[Current principles of the use of laparoscopic surgery in gastroduodenal ulcer]. ( Fedorov, AV; Sazhin, VP, 2001)
"In Bangladesh, late recrudescence of H."1.31Recrudescence and reinfection with Helicobacter pylori after eradication therapy in Bangladeshi adults. ( Ahmad, MM; Arefin, MS; Bardhan, P; Bauerfeind, P; Beglinger, C; Glatz-Krieger, K; Gyr, N; Hasan, M; Hildebrand, P; Khan, AK; Parvin, S; Rahman, A; Rossi, L; Terracciano, L, 2001)
"Therefore, the recurrence rate of H."1.31Six-year follow-up after successful triple therapy for Helicobacter pylori infection in patients with peptic ulcer disease. ( Kleibeuker, JH; Thijs, JC; van der Wouden, EJ; van Zwet, AA, 2001)
"Metronidazole resistance was found in 6."1.30Helicobacter pylori in gastric biopsies of Taiwanese patients with gastroduodenal diseases. ( Chang, YS; Cheng, KS; Lin, CW; Wu, SC, 1998)
" Discouraging the use of over-the-counter H2 antagonists, ruling out long-term use of nonsteroidal anti-inflammatory drugs before selecting the treatment regimen, and considering expected treatment compliance are important aspects of PUD management that emerged from this case."1.30Understanding peptic ulcer disease pharmacotherapeutics. ( Navuluri, R; Yue, S, 1999)
"One hundred and thirty patients with proven H pylori infection (by at least two tests) were treated with low dose triple therapy (DeNol 1 qid, tetracycline 250 mg qid and metronidazole 200 mg qid for 2 weeks; dosing with meals and at night); 83 were given a standard prescription for triple therapy (dispensed in bottles) and 47 were given a medication pack with times of dosing clearly marked."1.29An audit of low dose triple therapy for eradication of Helicobacter pylori. ( Ali, MR; Chua, LE; Fraser, AG; Hollis, B; Little, SV; Moore, L, 1996)
"Pre-treatment metronidazole susceptible H pylori were significantly more likely to respond to the triple therapy used than those with the metronidazole resistant ones (14 of 15 v five of 10) (p = 0."1.29Prevalence of metronidazole resistant Helicobacter pylori strains among Chinese peptic ulcer disease patients and normal controls in Hong Kong. ( Ching, CK; Lai, CL; Lai, KC; Lam, SK; Leung, KP; Wong, BC; Yung, RW, 1996)
"Its relationship to gastritis has not been studied."1.29Gastric mucosal hepatocyte growth factor in Helicobacter pylori gastritis and peptic ulcer disease. ( Beattie, AD; Curry, GW; Morton, R; Park, RH; Taha, AS, 1996)

Research

Studies (255)

TimeframeStudies, this research(%)All Research%
pre-19908 (3.14)18.7374
1990's120 (47.06)18.2507
2000's88 (34.51)29.6817
2010's31 (12.16)24.3611
2020's8 (3.14)2.80

Authors

AuthorsStudies
Gisbert, JP5
Alcedo, J1
Amador, J1
Bujanda, L1
Calvet, X5
Castro-Fernández, M1
Fernández-Salazar, L1
Gené, E2
Lanas, Á1
Lucendo, AJ1
Molina-Infante, J2
Nyssen, OP1
Pérez-Aisa, A2
Puig, I1
Zhou, Y1
Li, T1
Zhang, W2
Gui, Q1
Chen, J2
Yu, D1
Su, W1
Zhu, C1
Liang, X2
Lu, H2
Vu, TB1
Tran, TNQ1
Tran, TQA1
Vu, DL1
Hoang, VT1
Guevara, B1
Cogdill, AG1
Thieu, H1
Bach Dat, B1
Nam, NH1
Reda, A1
Duc, NT1
Alshareef, A1
Nguyen, JG1
Ngoc, NM1
Tien Huy, N1
Tang, Y1
Tang, G1
Pan, L1
Zhu, H1
Zhou, S1
Wei, Z1
Van Thieu, H1
Duc, NM1
Nghi, BTD1
Van Bach, N1
Khoi, HH1
Tien, VNT1
Bang, MTL1
Ngoc, TLC1
Yurenev, GL1
Partzvania-Vinogradova, EV1
Andreev, DN1
Dicheva, DT1
Maiev, IV1
Malfertheiner, P3
Seyedmajidi, S1
Mirsattari, D1
Zojaji, H1
Zanganeh, E1
Seyyedmajidi, M1
Almasi, S1
Zali, M1
Sierra, F1
Forero, JD1
Rey, M1
Botero, ML1
Cárdenas, A1
McNicholl, AG1
Marin, AC1
Castro, M1
Barrio, J1
Ducons, J2
de la Coba, C1
Montoro, M2
Bory, F2
Forné, M1
Onal, IK1
Gokcan, H1
Benzer, E1
Bilir, G1
Oztas, E1
Kim, SG1
Jung, HK1
Lee, HL1
Jang, JY1
Lee, H1
Kim, CG1
Shin, WG1
Shin, ES1
Lee, YC1
Kim, MS1
Kim, N5
Kim, SE1
Jo, HJ1
Shin, CM2
Park, YS2
Lee, DH4
Tu, S1
Yang, H1
Chung, KH1
Jin, E1
Cho, Y1
Seo, JY1
Jeong, SH1
Kim, JW2
Hwang, JH2
Scherübl, H1
Fischbach, W1
Glocker, E1
Andrianov, M1
Rivera, E1
Azzam, R1
Bai, P1
Zhou, LY1
Xiao, XM1
Luo, Y1
Ding, Y1
Tepeš, B1
Vujasinović, M1
Šeruga, M1
Stefanovič, M1
Forte, A1
Jeverica, S1
Murakami, K6
Sakurai, Y1
Shiino, M1
Funao, N1
Nishimura, A1
Asaka, M3
Hu, B1
Zhao, F1
Wang, S1
Olszewski, MA1
Bian, H1
Wu, Y1
Kong, M1
Xu, L1
Miao, Y1
Fang, Y1
Yang, C1
Zhao, H1
Zhang, Y1
Georgopoulos, SD1
Xirouchakis, E1
Martinez-Gonzales, B1
Zampeli, E1
Grivas, E1
Spiliadi, C1
Sotiropoulou, M1
Petraki, K1
Zografos, K1
Laoudi, F1
Sgouras, D1
Mentis, A1
Kasapidis, P1
Michopoulos, S1
Legendre, T1
Boudebesse, C1
Henry, C1
Etain, B1
Lin, LC1
Hsu, TH1
Huang, KW1
Tam, KW1
Chen, Q1
Fu, Q1
Liu, W1
Xiao, S1
Oyedeji, KS1
Smith, SI1
Coker, AO1
Arigbabu, AO1
Abdou, AG1
Elshayeb, EI1
Farag, AG1
Elnaidany, NF1
Singh, V1
Mishra, S1
Maurya, P1
Rao, G1
Jain, AK1
Dixit, VK1
Gulati, AK1
Nath, G1
Kim, JJ1
Choe, YH1
Kim, HS1
Kim, JI1
Chung, IS1
Kivistö, R1
Linros, J1
Rossi, M1
Rautelin, H3
Hänninen, ML1
Gawrońska-Szklarz, B2
Siuda, A2
Kurzawski, M2
Bielicki, D1
Marlicz, W1
Droździk, M2
Ben Mansour, K1
Burucoa, C1
Zribi, M1
Masmoudi, A1
Karoui, S1
Kallel, L1
Chouaib, S1
Matri, S1
Fekih, M1
Zarrouk, S1
Labbene, M1
Boubaker, J1
Cheikh, I1
Hriz, MB1
Siala, N1
Ayadi, A1
Filali, A1
Mami, NB1
Najjar, T1
Maherzi, A1
Sfar, MT1
Fendri, C1
Kampitak, T1
Koizumi, W1
Tanabe, S1
Nakatani, K1
Ishido, K1
Nishimura, K1
Azuma, M1
Ae, T1
Sasaki, T1
Higuchi, K1
Katada, C1
Nakayama, N1
Saigenji, K1
Riahizadeh, S1
Malekzadeh, R2
Agah, S1
Zendehdel, N1
Sotoudehmanesh, R1
Ebrahimi-Dariani, N1
Pourshams, A1
Vahedi, H2
Mikaeli, J1
Khatibian, M1
Massarrat, S2
Bytzer, P1
Dahlerup, JF1
Eriksen, JR1
Jarbøl, DE1
Rosenstock, S1
Wildt, S1
Park, HG1
Jung, MK1
Jung, JT1
Kwon, JG1
Kim, EY1
Seo, HE1
Lee, JH2
Yang, CH1
Kim, ES1
Cho, KB1
Park, KS1
Lee, SH1
Kim, KO1
Jeon, SW1
Shcherbakov, PL1
Ianova, OB1
Belousova, NL1
Masharova, AA1
Shcherbakova, MIu1
Goncharenko, LS1
Firsova, LD1
Kim, VA1
Govorun, VM1
Kashnikov, VS1
Figura, N1
Moretti, E1
Vaglio, L1
Langone, F1
Vernillo, R1
Vindigni, C1
Giordano, N1
Shah, A1
Javid, G1
Zargar, SA1
Teli, F1
Khan, BA1
Yattoo, GN1
Gulzar, GM1
Sodhi, JS1
Khan, MA1
Shoukat, A1
Saif, R1
Guardiola, J1
Tito, L1
Andreu, V1
Guirao, R2
Boixeda, D2
Bermejo, F1
Martín-De-Argila, C1
López-Sanromán, A1
Defarges, V1
Hernández-Ranz, F1
Milicua, JM1
García-Plaza, A1
Schuster, MJ1
Olafsson, S3
Hatlebakk, JG4
Berstad, A6
Toro, C1
García-Samaniego, J1
Alarcón, T1
Baquero, M1
Eun, CS2
Han, DS2
Park, JY1
Jeon, YC2
Hahm, JS2
Kim, KS1
Kang, JO2
Unge, P1
Kimura, K2
Sipponen, P2
Ekström, P1
Satoh, K1
Hellblom, M1
Ohlin, B1
Stubberöd, A1
Kihira, K2
Yube, T1
Yoshida, Y2
Laine, L3
Bakumov, PA1
Shchepotkin, IV1
Dugina, YL1
Epstein, OI1
Sergeeva, SA1
Lui, SY1
Yeoh, KG2
Ho, B2
Neuhann, HF1
Swai, B1
Carpenter, CF1
Shao, O1
Bochenek, WJ1
Peters, S1
Fraga, PD1
Wang, W1
Mack, ME1
Osato, MS2
El-Zimaity, HM3
Davis, KD1
Graham, DY7
Gambaro, C1
Bilardi, C1
Dulbecco, P1
Iiritano, E1
Zentilin, P1
Mansia, C1
Usai, P1
Vigneri, S1
Savarino, V2
Thyagarajan, SP1
Ray, P1
Das, BK1
Ayyagari, A2
Khan, AA1
Dharmalingam, S1
Rao, UA1
Rajasambandam, P1
Ramathilagam, B1
Bhasin, D1
Sharma, MP2
Naik, SR1
Habibullah, CM1
Färkkilä, M2
Sarna, S1
Valtonen, V1
Bhatia, V1
Ahuja, V1
Das, B1
Bal, C1
Fraser, A1
Wheeldon, TU1
Granström, M1
Hoang, TT1
Phuncarg, DC1
Nilsson, LE1
Sörberg, M2
Janssen, MJ2
Laheij, RJ2
Jansen, JB2
de Boer, WA11
Schuster, M1
Saad, R1
Chey, WD2
Hu, YY1
Zhou, ZF1
Nan, Q1
Jiang, HY1
Zhang, L1
Li, XY1
Duan, LP1
Chen, YR1
Sun, WH1
Ou, XL1
Cao, DZ1
Yu, Q1
Yu, T1
Hu, JM1
Zhu, F1
Sun, YL1
Fu, XL1
Su, H1
Cheon, JH1
Park, MJ1
Kim, JM1
Kim, JS1
Jung, HC2
Song, IS2
Chen, FB1
Yu, JD1
Chen, XJ1
Li, ZY1
Zhang, XP1
Albert, TJ1
Dailidiene, D1
Dailide, G1
Norton, JE1
Kalia, A1
Richmond, TA1
Molla, M1
Singh, J1
Green, RD1
Berg, DE1
Matsushima, M1
Suzuki, T1
Kurumada, T2
Watanabe, S2
Watanabe, K3
Kobayashi, K1
Deguchi, R1
Masui, A1
Takagi, A2
Shirai, T2
Muraoka, H2
Kobayashi, I2
Mine, T1
Sato, R3
Okimoto, T3
Nasu, M1
Fujioka, T4
Kodama, M3
Abe, T1
Sato, S1
Arita, T1
Butorov, IV2
Osoianu, IuP2
Butorov, SI2
Maksimov, VV2
Koletzko, S1
Richy, F1
Bontems, P1
Crone, J1
Kalach, N1
Monteiro, ML1
Gottrand, F1
Celinska-Cedro, D1
Roma-Giannikou, E1
Orderda, G1
Kolacek, S1
Urruzuno, P1
Martínez-Gómez, MJ1
Casswall, T1
Ashorn, M1
Bodanszky, H1
Mégraud, F1
Díte, P1
Kunovská, M1
Pulgretová, D1
Woznica, V1
Petrtýl, J1
Hůlek, P1
Pásková, J1
Dostalík, Z1
Novotný, I1
Procházka, V1
Hegyi, P1
Zelenková, J1
Samek, M1
Králová, Z1
Vyhnálek, P1
Matejovic, F1
Weinberg, J1
Kyzeková, J1
Hendrikse, L1
de Boer, SY2
Bosboom, R1
Wrześniewska, J1
Starzyńska, T1
Dzieniszewski, J1
Jarosz, M1
Emami, MH1
Saberfiroozi, MM1
Arj, A1
Taghavi, AR1
Bagheri-Lankarani, K1
Dehbashi, N1
Fattahi, MR1
Alizadeh, M1
Kaviani, MJ2
Bahri-Najafi, R1
Geramizadeh, B1
Esmaeili, A1
Chung, SJ1
Jung, SH1
Lee, KH1
Fuccio, L1
Minardi, ME1
Zagari, RM1
Grilli, D1
Magrini, N1
Bazzoli, F1
Bang, SY1
Kim, JE1
Ahn, SB1
Sohn, JH1
Hansen, JM1
Wildner-Christensen, M1
Hallas, J1
Schaffalitzky de Muckadell, OB1
Baker, DE1
Bjørneklett, A1
Fausa, O1
Midtvedt, T1
Shirokova, KI1
Filimonov, RM1
Poliakova, LV1
Domschke, W1
Dettmer, A1
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Hesse, P1
Holtmann, G1
van Husen, N1
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Schentke, KU1
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Tytgat, GN8
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Soll, AH1
Tefera, S2
Taha, AS1
Curry, GW1
Morton, R1
Park, RH1
Beattie, AD1
Ching, CK1
Leung, KP1
Yung, RW1
Lam, SK1
Wong, BC1
Lai, KC1
Lai, CL1
Peitz, U1
Fraser, AG1
Moore, L1
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Chua, LE1
Hollis, B1
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Bergseth, M1
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Itoyama, S1
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el-Omar, EM1
Dickson, A2
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Lahaie, R1
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van der Wouden, EJ2
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Kleibeuker, JH2
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Kouda, K1
Tada, U1
Wada, T1
Harasawa, S1
Miwa, T1
Sato, K2
Kumakura, Y1
Sugano, K1
Kung, NN1
Sung, JJ2
Yuen, NW1
Li, TH1
Ng, PW1
Lai, WM1
Lui, YH1
Lam, KN1
Choi, CH1
Leung, EM1
Navuluri, R1
Yue, S1
Lin, CW1
Chang, YS1
Wu, SC1
Cheng, KS1
Pilotto, A1
Franceschi, M1
Leandro, G1
Bozzola, L1
Fortunato, A1
Rassu, M1
Meli, S1
Soffiati, G1
Scagnelli, M1
Di Mario, F1
Valerio, G1
Grimley, CE1
Penny, A1
O'sullivan, M1
Shebani, M1
Lismore, JR1
Cross, R1
Illing, RC1
Loft, DE1
Nwokolo, CU1
Houben, MH1
Hensen, EF1
Rauws, EA1
Hulst, RW1
Hoff, BW1
Ende, AV1
Kate, FJ1
Chan, FK1
Wu, JC1
Leung, WK1
Suen, R1
Ling, TK1
Lee, YT1
Cheng, AF1
Chung, SC1
Ellenrieder, V1
Boeck, W1
Richter, C1
Marre, R1
Adler, G1
Glasbrenner, B1
Boyanova, L2
de Grauw, WJ1
Tanigawara, Y1
Aoyama, N1
Kita, T1
Shirakawa, K1
Komada, F1
Kasuga, M1
Okumura, K1
Ducóns, JA3
Ferrero, M3
García Cabezudo, J1
Simón, MA1
Nishikawa, K1
Ishizuka, J1
Kudo, T1
Komatsu, Y1
Katagiri, M1
Sukegawa, M1
Kagaya, H1
Takeda, H1
Toyota, J1
El-Omar, E1
Kelman, A1
Taskin, V1
Gurer, I1
Ozyilkan, E1
Sare, M1
Hilmioglu, F1
van Doorn, LJ2
Nouhan, N1
Plaisier, AP1
Quint, WG1
Lõivukene, K1
Kolk, H1
Maaroos, HI1
Kasenõmm, P1
Ustav, M1
Mikelsaar, M1
Adamsson, I1
Edlund, C1
Nord, CE1
Stancheva, I1
Spassova, Z1
Katzarov, N1
Mitov, I1
Koumanova, R1
Azuma, T1
Ito, S1
Suto, H1
Ito, Y1
Miyaji, H1
Yamazaki, Y1
Kato, T1
Kuriyama, M1
Teo, EK1
Ng, TM1
Khor, CJ1
Tan, AL1
Piqué, JM1
Romero Gómez, M1
Martínez Delgado, C1
Grande, L1
Otero Fernández, MA1
Vargas, J1
Castro Fernández, M1
Sicilia, B2
Sierra, E2
Revillo, MJ1
Giannini, E1
Romagnoli, P1
Fasoli, A1
Chiarbonello, B1
Malfatti, F1
Botta, F1
Risso, D1
Lantieri, PB1
Testa, R1
Bezborodnyĭ, SD1
Santolaria, S1
María Pajares, J1
Katelaris, PH1
Satoh, R1
Kagawa, J1
Avidan, B1
Melzer, E1
Keller, N1
Bar-Meir, S1
Sanfeliu, I1
Murphy, B1
Kusters, JG1
Kuipers, EJ1
Nagahara, A1
Miwa, H1
Ohkura, R1
Yamada, T1
Hojo, M1
Sato, N1
Bardhan, KD1
Morton, D1
Perry, MJ1
Sanders, DS1
Morris, P1
Rowland, A1
Thompson, M1
Mitchell, TR1
Roberts, PM1
Sotoudeh, M1
Kamalian, N1
Amini, M1
Sazhin, VP1
Fedorov, AV1
Maev, IV1
Samsonov, A1
Val'tova, ED1
Ismailova, MZ1
Ovchinnikova, NI1
Hildebrand, P1
Bardhan, P1
Rossi, L1
Parvin, S1
Rahman, A1
Arefin, MS1
Hasan, M1
Ahmad, MM1
Glatz-Krieger, K1
Terracciano, L1
Bauerfeind, P1
Beglinger, C1
Gyr, N1
Khan, AK1
Tankovic, J1
Lamarque, D1
Lascols, C1
Soussy, CJ1
Delchier, JC1
Marcos, S1
Gisbert, JL1
He, JX1
Akao, T1
Nishino, T1
Tani, T1
Wittig, J1
Ammon, S1
Walker, S1
Klotz, U1
Yamamoto, N1
Sakagami, T1
Fukuda, Y1
Shimoyama, T1
Fu, HY1
Kawano, S1
Tanimura, H1
Hiraishi, H1
Kanke, K1
Terano, A1
Kuwayama, H1
Takahashi, M1
Suzuki, K1
Suga, M1
Takata, H1
Ohara, T1
Koizumi, K1
Kiriyama, Y1
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Forné Bardera, M1
Quintana Riera, S1
Lite Lite, J1
Garau Alemany, J1
Harikrishnan, P1
Bindayna, KM1
Hasegawa, M1
Saika, T1
Nishida, M1
Kawamura, M1
Ando, R1
Skornetskiĭ, BD2
Gavrilenko, IaV2
Vazilo, VE1
Parshkov, EM1
Pichugin, IuI1
Lebreton, JM1
Nuutinen, H1
Hakala, K1
Väänänen, H1
Smoot, DT1
Scott, VF1
Bhatia, RS1
Nigam, P1
Lewis, JH1
Weingold, AB1
Quintero Diaz, M1
Sotto Escobar, A1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 4, Prospective, Randomized and Comparative Study Comparing Sequential and Concomitant Therapy for Helicobacter Pylori Eradication in Routine Clinical Practice[NCT01273441]Phase 4338 participants (Actual)Interventional2010-12-31Completed
[NCT01792700]Phase 4648 participants (Actual)Interventional2003-01-31Completed
Comparison of Vonoprazan and Amoxicillin Dual Therapy With Standard Triple Therapy With Proton Pump Inhibitor for Helicobacter Pylori Eradication; a Randomized Control Trial[NCT04901663]Phase 4179 participants (Actual)Interventional2021-06-21Completed
A Phase 3, Randomized, Double-Blind, Double Dummy, Multicenter, Parallel Group Comparison Study to Evaluate Efficacy and Safety of a Triple Therapy With TAK-438, Amoxicillin and Clarithromycin by Comparison With a Triple Therapy With AG-1749 (Lansoprazole[NCT01505127]Phase 3650 participants (Actual)Interventional2012-01-31Completed
10 Day Concomitant Versus 14 Day Hybrid Regimen as First Line H. Pylori Eradication Treatment in a High Clarithromycin Resistance Area. A Multicenter Randomized Equivalence Trial[NCT03592069]Phase 4345 participants (Actual)Interventional2018-02-21Completed
Eradication of Helicobacter Pylori According to 23S rRNA Point Mutations Associated With Clarithromycin Resistance[NCT01453036]Phase 4924 participants (Actual)Interventional2011-08-31Completed
Phase IV Study Comparing Helicobacter Pylori Empiric Eradication With Test-Guided Treatment in Patients With Peptic Ulcer Bleeding[NCT00687336]Phase 4178 participants (Anticipated)Interventional2008-03-31Recruiting
Comparison of Clinical Outcomes in Bloodstream Infections With Carbapenem Hetero-resistant vs Carbapenem Resistant Klebsiella Pneumoniae (COMBAT)[NCT04229498]300 participants (Anticipated)Observational2020-04-30Not yet recruiting
Personalized Treatment for Refractory H Pylori Infection[NCT02547025]126 participants (Actual)Interventional2012-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Helicobacter Pylori Eradication Rate

Eradication was determined by the C13-urea breath test 6 to 8 weeks after the eradication therapy when PPIs had not been used for at least 2 weeks. (NCT01453036)
Timeframe: 8 weeks

Interventionpercentage of participants (Number)
Convential AOC Group75.9
Mutation Test Group91.2
Convential AOM Group79.1

Reviews

42 reviews available for metronidazole and Gastroduodenal Ulcer

ArticleYear
V Spanish Consensus Conference on Helicobacter pylori infection treatment.
    Gastroenterologia y hepatologia, 2022, Volume: 45, Issue:5

    Topics: Amoxicillin; Anti-Bacterial Agents; Bismuth; Clarithromycin; Drug Therapy, Combination; Helicobacter

2022
Helicobacter pylori: A Review of Current Diagnostic and Management Strategies.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:7

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antigens, Bacterial; Biopsy; Bismuth; Breath

2020
[What is new in treating Helicobacter pylori infection?].
    Deutsche medizinische Wochenschrift (1946), 2015, Volume: 140, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Child; Clarithromycin; Drug Resistance, Bacterial; Drug Therapy, Combi

2015
[Antibiomania: Think of the manic syndrome secondary to antibiotic therapy].
    L'Encephale, 2017, Volume: 43, Issue:2

    Topics: Amoxicillin; Anti-Bacterial Agents; Bipolar Disorder; Clarithromycin; Drug Therapy, Combination; Fem

2017
Nonbismuth concomitant quadruple therapy for Helicobacter pylori eradication in Chinese regions: A meta-analysis of randomized controlled trials.
    World journal of gastroenterology, 2016, Jun-21, Volume: 22, Issue:23

    Topics: Amoxicillin; Anti-Bacterial Agents; China; Clarithromycin; Disease Eradication; Drug Therapy, Combin

2016
Diagnosis and treatment of Helicobacter pylori infection.
    Danish medical bulletin, 2011, Volume: 58, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Antidiarrheals; Bismuth; Clarithromycin; Denmark; Drug Therapy,

2011
[Helicobacter pylori. Update 2002].
    Praxis, 2002, Nov-27, Volume: 91, Issue:48

    Topics: Adenocarcinoma; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Duode

2002
Is it time for quadruple therapy to be first line?
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2003, Volume: 17 Suppl B

    Topics: Amoxicillin; Antacids; Anti-Infective Agents; Bismuth; Clarithromycin; Clinical Trials as Topic; Dru

2003
[Helicobacter pylori: reasons for eradication].
    Praxis, 2004, Dec-22, Volume: 93, Issue:51-52

    Topics: Adenocarcinoma; Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Gastritis

2004
A clinician's guide to managing Helicobacter pylori infection.
    Cleveland Clinic journal of medicine, 2005, Volume: 72, Issue:2

    Topics: Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Diagnosis, Differential; Endoscopy; Gastrointestinal

2005
Meta-analysis: duration of first-line proton-pump inhibitor based triple therapy for Helicobacter pylori eradication.
    Annals of internal medicine, 2007, Oct-16, Volume: 147, Issue:8

    Topics: Amoxicillin; Anti-Bacterial Agents; Drug Administration Schedule; Drug Therapy, Combination; Dyspeps

2007
Pylera plus omeprazole: quadruple treatment for Helicobacter pylori.
    Reviews in gastroenterological disorders, 2008,Winter, Volume: 8, Issue:1

    Topics: Antacids; Anti-Infective Agents; Anti-Ulcer Agents; Bismuth; Capsules; Drug Therapy, Combination; He

2008
Treating peptic ulcer: an ongoing challenge.
    The Journal of the American Osteopathic Association, 1995, Volume: 95, Issue:4

    Topics: Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combina

1995
[Management of the peptic ulcer patient in the Helicobacter pylori age].
    Enfermedades infecciosas y microbiologia clinica, 1994, Volume: 12 Suppl 1

    Topics: Algorithms; Antacids; Anti-Bacterial Agents; Biopsy; Bismuth; Breath Tests; Child; Drug Therapy, Com

1994
Helicobacter pylori in peptic ulcer disease.
    Delaware medical journal, 1994, Volume: 66, Issue:10

    Topics: Amoxicillin; Anti-Bacterial Agents; Bismuth; Drug Therapy, Combination; Helicobacter Infections; Hel

1994
The role of acid inhibition in the treatment of Helicobacter pylori infection.
    Scandinavian journal of gastroenterology. Supplement, 1994, Volume: 201

    Topics: Amoxicillin; Depression, Chemical; Drug Administration Schedule; Drug Therapy, Combination; Gastric

1994
Helicobacter pylori: consensus reached: peptic ulcer is on the way to becoming an historic disease.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:8

    Topics: Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Gastritis; Helicobacter Infections; Helicobac

1994
[Treatment of Helicobacter pylori infection in adults].
    Enfermedades infecciosas y microbiologia clinica, 1994, Volume: 12 Suppl 1

    Topics: Antacids; Anti-Bacterial Agents; Bismuth; Drug Resistance, Microbial; Drug Therapy, Combination; Gas

1994
Consensus conference. Medical treatment of peptic ulcer disease. Practice guidelines. Practice Parameters Committee of the American College of Gastroenterology.
    JAMA, 1996, Feb-28, Volume: 275, Issue:8

    Topics: Antacids; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Biopsy;

1996
Bismuth therapy for Helicobacter pylori infection. A review of five years experience at a university hospital in Norway.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1996, Volume: 47, Issue:1

    Topics: Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Follow-Up St

1996
Critical evaluation of the treatment of peptic ulcer diseases associated with Helicobacter pylori infection.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1996, Volume: 47, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clarithromycin; Drug Therapy, Combin

1996
[Helicobacter pylori eradication: triple therapy versus dual therapy].
    Fortschritte der Medizin, 1996, Feb-10, Volume: 114, Issue:4

    Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Clarithromycin; Clinical Trials as Topic; Drug Therapy, Com

1996
Treatment strategies for Helicobacter pylori infection.
    American family physician, 1997, Volume: 55, Issue:8

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clarithromycin; Drug Therapy, Combin

1997
Review: Helicobacter pylori. Current issues and new directions.
    Journal of gastroenterology and hepatology, 1997, Volume: 12, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bismuth; Drug Therapy, Combination;

1997
Peptic ulcer disease in the 1990s: an Asian perspective.
    Journal of gastroenterology and hepatology, 1997, Volume: 12, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Asia; Bismu

1997
Current European concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. European Helicobacter Pylori Study Group.
    Gut, 1997, Volume: 41, Issue:1

    Topics: Amoxicillin; Antitrichomonal Agents; Clarithromycin; Drug Administration Schedule; Drug Therapy, Com

1997
[Helicobacter pylori infection and ulcer].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1998, Volume: 69, Issue:3

    Topics: Amoxicillin; Clarithromycin; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori

1998
[Problems following antibiotic therapy for eradication of Helicobacter pylori].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1998, May-10, Volume: 87, Issue:5

    Topics: Amoxicillin; Anti-Bacterial Agents; Antitrichomonal Agents; Clarithromycin; Drug Resistance, Microbi

1998
Helicobacter pylori and peptic ulcer disease. Current evidence for management strategies.
    Canadian family physician Medecin de famille canadien, 1998, Volume: 44

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Evidence-Based Medicine; Family

1998
[Antibiotic-resistant H. pylori strains in the last ten years in Japan].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Microbial; Helicobacter Infecti

1999
[Eradication rate and side effect from a point of view of Helicobacter pylori eradication of peptic ulcer disease in dual therapy or new triple therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clar

1999
Microbial ecology and treatment of Helicobacter pylori infections: review.
    Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin;

2000
[Helicobacter pylori resistance to metronidazole and to clarithromycin in Spain. A systematic review].
    Medicina clinica, 2001, Jan-27, Volume: 116, Issue:3

    Topics: Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Microbial; Helicobacter Infections; Helicoba

2001
[Selection of antibiotics and planning of eradication for H. pylori infection].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Administr

2001
Helicobacter pylori: a clinical update.
    Symposium series (Society for Applied Microbiology), 2001, Issue:30

    Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Clinical Trials as Topic; Drug Therapy, Combinat

2001
Antibiotic resistance of Helicobacter pylori.
    Symposium series (Society for Applied Microbiology), 2001, Issue:30

    Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Microbial; Helicobacter Infecti

2001
Helicobacter pylori therapy: first-line options and rescue regimen.
    Digestive diseases (Basel, Switzerland), 2001, Volume: 19, Issue:2

    Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Microbial; Drug Therapy, Combin

2001
[Development of Helicobacter pylori eradication therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: Amoxicillin; Animals; Clarithromycin; Drug Therapy, Combination; Helicobacter Infections; Helicobact

2002
[Dual therapy for Helicobacter pylori resistance to anti microbial agents].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Clinical Trial

2002
[Sucralfate].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: Anti-Ulcer Agents; Clarithromycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Gastric Ac

2002
[Polaprezinc].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Animals; Anti-Ulcer Agents; Carnosine; Clarith

2002
The use of gastrointestinal drugs during pregnancy and lactation.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:11

    Topics: Adrenal Cortex Hormones; Animals; Antidiarrheals; Antiemetics; Cathartics; Diuretics; Female; Gastro

1985

Trials

99 trials available for metronidazole and Gastroduodenal Ulcer

ArticleYear
Intravenous metronidazole-, levofloxacin-containing triple therapy for treating patients with Helicobacter pylori-related active peptic ulcer complications: A pilot study.
    Helicobacter, 2023, Volume: 28, Issue:2

    Topics: Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Esomeprazole; Helicobacter Infections

2023
Evaluation of the efficacy and safety of the hybrid scheme for eradication therapy of Helicobacter pylori infection.
    Terapevticheskii arkhiv, 2018, Aug-27, Volume: 90, Issue:8

    Topics: Adult; Amoxicillin; Antacids; Anti-Infective Agents; Anti-Ulcer Agents; Bismuth; Clarithromycin; Dru

2018
[Is sequential eradication of Helicobacter pylori effective? Sequential treatment more effective than triple therapy in patients with clarithromycin resistance].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:13

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clar

2013
Penbactam for Helicobacter pylori eradication: a randomised comparison of quadruple and triple treatment schedules in an Iranian population.
    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 2013, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Ampicillin; Analysis of Variance; Anti-Bact

2013
Randomised clinical trial comparing sequential and concomitant therapies for Helicobacter pylori eradication in routine clinical practice.
    Gut, 2014, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; B

2014
Long-term follow up Helicobacter Pylori reinfection rate after second-line treatment: bismuth-containing quadruple therapy versus moxifloxacin-based triple therapy.
    BMC gastroenterology, 2013, Sep-19, Volume: 13

    Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Aza Compounds; Breath Tests; Disease-Fr

2013
Randomized clinical trial comparing 10-day sequential, 7-day concomitant and 7-day standard triple therapies for Helicobacter pylori eradication.
    European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Administration Sch

2016
Vonoprazan, a novel potassium-competitive acid blocker, as a component of first-line and second-line triple therapy for Helicobacter pylori eradication: a phase III, randomised, double-blind study.
    Gut, 2016, Volume: 65, Issue:9

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Double-Blind Method; Drug A

2016
Vonoprazan, a novel potassium-competitive acid blocker, as a component of first-line and second-line triple therapy for Helicobacter pylori eradication: a phase III, randomised, double-blind study.
    Gut, 2016, Volume: 65, Issue:9

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Double-Blind Method; Drug A

2016
Vonoprazan, a novel potassium-competitive acid blocker, as a component of first-line and second-line triple therapy for Helicobacter pylori eradication: a phase III, randomised, double-blind study.
    Gut, 2016, Volume: 65, Issue:9

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Double-Blind Method; Drug A

2016
Vonoprazan, a novel potassium-competitive acid blocker, as a component of first-line and second-line triple therapy for Helicobacter pylori eradication: a phase III, randomised, double-blind study.
    Gut, 2016, Volume: 65, Issue:9

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Double-Blind Method; Drug A

2016
Randomized clinical trial comparing ten day concomitant and sequential therapies for Helicobacter pylori eradication in a high clarithromycin resistance area.
    European journal of internal medicine, 2016, Volume: 32

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Biopsy; Breath Tests; Carbon Isotopes; Clarithromyc

2016
Rescue Therapy for Helicobacter pylori Eradication: A Randomized Non-Inferiority Trial of Amoxicillin or Tetracycline in Bismuth Quadruple Therapy.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:12

    Topics: Adult; Aged; Amoxicillin; Antacids; Anti-Bacterial Agents; Bismuth; Drug Resistance, Bacterial; Drug

2016
Sequential metronidazole-furazolidone or clarithromycin-furazolidone compared to clarithromycin-based quadruple regimens for the eradication of Helicobacter pylori in peptic ulcer disease: a double-blind randomized controlled trial.
    Helicobacter, 2010, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Double-Blind Meth

2010
Randomised clinical trial: a comparative study of 10-day sequential therapy with 7-day standard triple therapy for Helicobacter pylori infection in naïve patients.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2012
[Enterofuril eradication therapy in chronic inflammatory diseases of the upper digestive tract].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2011, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Infective Agents; Chronic Disease; Clarithromyc

2011
Safety and efficacy of 1-week levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori-related peptic ulcer disease in Kashmir, India.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2013, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Schedule; Dru

2013
One-week triple vs. quadruple therapy for Helicobacter pylori infection - a randomized trial.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:7

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Administration S

2002
Efficacy of quadruple therapy with pantoprazole, bismuth, tetracycline and metronidazole as rescue treatment for Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2002
Patients with endoscopic gastritis and/or duodenitis improve markedly following eradication of Helicobacter pylori, although less so than patients with ulcers.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Duodenitis; Female; Fo

2002
Do Japanese and Swedish peptic ulcer patients respond differently to Helicobacter pylori eradication therapies and what are their histological features?
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:5

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Asian People; Clarithromycin; Dr

2003
Clinical efficiency of Epigam in patients with exacerbation of peptic ulcer disease of the stomach and duodenum.
    Bulletin of experimental biology and medicine, 2003, Volume: 135 Suppl 7

    Topics: Adolescent; Adult; Amoxicillin; Anti-Ulcer Agents; Antibodies; Dose-Response Relationship, Drug; Dru

2003
Efficacy of different antibiotic regimens for eradication treatment of Helicobacter pylori infection in peptic ulcer disease in Tanzanian patients.
    Tropical doctor, 2003, Volume: 33, Issue:4

    Topics: Adult; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Clarithromycin; Drug Administration Sc

2003
Eradication of Helicobacter pylori by 7-day triple-therapy regimens combining pantoprazole with clarithromycin, metronidazole, or amoxicillin in patients with peptic ulcer disease: results of two double-blind, randomized studies.
    Helicobacter, 2003, Volume: 8, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; An

2003
Comparable Helicobacter pylori eradication rates obtained with 4- and 7-day rabeprazole-based triple therapy: a preliminary study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2003, Volume: 35, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Ag

2003
Does the 'test-and-treat' strategy work in primary health care for management of uninvestigated dyspepsia? A prospective two-year follow-up study of 1552 patients.
    Scandinavian journal of gastroenterology, 2004, Volume: 39, Issue:4

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Dyspepsia; Endoscopy, Gastrointestinal

2004
Use of imidazole-based eradication regimens for Helicobacter pylori should be abandoned in North India regardless of in vitro antibiotic sensitivity.
    Journal of gastroenterology and hepatology, 2004, Volume: 19, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents;

2004
The importance of the level of metronidazole resistance for the success of Helicobacter pylori eradication.
    Alimentary pharmacology & therapeutics, 2004, Jun-15, Volume: 19, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; D

2004
The influence of pretreatment on cure rates of Helicobacter pylori eradication.
    The Netherlands journal of medicine, 2004, Volume: 62, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Anti-Infective Agents; Anti-Ulcer Agents; Bismuth

2004
Efficacy of omeprazole and amoxicillin with either clarithromycin or metronidazole on eradication of Helicobacter pylori in Chinese peptic ulcer patients.
    World journal of gastroenterology, 2005, Apr-28, Volume: 11, Issue:16

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Asian People; Clarithromycin

2005
Effectiveness of minocycline-based triple therapy for eradication of Helicobacter pylori infection.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:1 Pt 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2006
[Comparison of the effectiveness of tri- and quadricomponent eradication therapy in patients with peptic ulcer].
    Klinicheskaia meditsina, 2005, Volume: 83, Issue:12

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Administrat

2005
[Double blind randomized multicentre study of a seven-day eradication regime of Helicobacter pylori by omeprazole, clarithromycin and ornidazole vs. omeprazole, clarithromycin and metronidazole].
    Vnitrni lekarstvi, 2002, Volume: 48, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Double-Blind Meth

2002
Does delayed gastric emptying shorten the H pylori eradication period? A double blind clinical trial.
    World journal of gastroenterology, 2006, Oct-21, Volume: 12, Issue:39

    Topics: Antacids; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Bismuth; Dopamine Agents;

2006
Evaluation of three different proton pump inhibitors with amoxicillin and metronidazole in retreatment for Helicobacter pylori infection.
    Journal of clinical gastroenterology, 2008, Volume: 42, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Infective Agents; Drug Therapy, Co

2008
Effect of a community screening for Helicobacter pylori: a 5-Yr follow-up study.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:5

    Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Community Health Services; Cost-Benefit Analy

2008
Spiramycin in triple therapy of Helicobacter pylori-associated peptic ulcer disease. An open pilot study with 12-month follow-up.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:2

    Topics: Adult; Aged; Bismuth; Breath Tests; Drug Therapy, Combination; Female; Follow-Up Studies; Helicobact

1995
Pharmacological effects of metronidazole+tetracycline+bismuth subcitrate versus omeprazole+amoxycillin+bismuth subcitrate in Helicobacter pylori-related gastritis and peptic ulcer disease.
    European journal of gastroenterology & hepatology, 1994, Volume: 6 Suppl 1

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Double-Blind Method; Drug Therapy, Com

1994
Modified short-term triple therapy--ranitidine, clarithromycin, and metronidazole--for cure of Helicobacter pylori infection.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:1

    Topics: Adult; Aged; Clarithromycin; Drug Therapy, Combination; Duodenitis; Female; Gastritis; Helicobacter

1995
One-week low-dose triple therapy for the eradication of Helicobacter pylori infection.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combinat

1995
Effect of acid suppression on efficacy of treatment for Helicobacter pylori infection.
    Lancet (London, England), 1995, Apr-01, Volume: 345, Issue:8953

    Topics: Adult; Aged; Anti-Ulcer Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Hel

1995
Causal role of Helicobacter pylori in peptic ulcer relapse.
    Journal of gastroenterology, 1994, Volume: 29 Suppl 7

    Topics: Aged; Amoxicillin; Bismuth; Chi-Square Distribution; Drug Therapy, Combination; Gastric Mucosa; Heli

1994
Omeprazole 40 mg o.m. combined with amoxycillin alone or with amoxycillin and metronidazole in the eradication of Helicobacter pylori.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:10

    Topics: Adult; Aged; Amoxicillin; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies;

1994
Helicobacter pylori eradication with bismuth subnitrate, oxytetracycline and metronidazole in patients with peptic ulcer disease.
    Hepato-gastroenterology, 1994, Volume: 41, Issue:1

    Topics: Adult; Aged; Antacids; Bismuth; Drug Therapy, Combination; Female; Helicobacter Infections; Helicoba

1994
Efficacy and side effects of a triple drug regimen for the eradication of Helicobacter pylori.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Administration Schedule; Drug Therapy, C

1993
Treatment of Helicobacter pylori reduces the rate of rebleeding in peptic ulcer disease.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:11

    Topics: Adult; Aged; Bismuth; Drug Therapy, Combination; Follow-Up Studies; Gastrointestinal Hemorrhage; Hel

1993
Triple therapy with ranitidine, clarithromycin, and metronidazole in the treatment of Helicobacter pylori.
    Scandinavian journal of gastroenterology. Supplement, 1995, Volume: 212

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Interactions; Drug Thera

1995
Bismuth-based combination therapy for Helicobacter pylori-associated peptic ulcer disease (metronidazole for eradication, ranitidine for pain).
    The American journal of gastroenterology, 1996, Volume: 91, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Bism

1996
Quadruple therapy compared with dual therapy for eradication of Helicobacter pylori in ulcer patients: results of a randomized prospective single-centre study.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Ant

1995
Only four days of quadruple therapy can effectively cure Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Th

1995
Long-term follow-up after cure of Helicobacter pylori infection with 4 days of quadruple therapy.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Dyspepsia; Heli

1996
Therapeutic options after failed Helicobacter pylori eradication therapy.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:11

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combinat

1996
Omeprazole plus amoxicillin versus triple therapy eradicates Helicobacter pylori in the Chinese with peptic ulcer disease.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1996, Volume: 57, Issue:3

    Topics: Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Drug Therapy, Combination; Female; Helicobacter pylori;

1996
One-day intensified lansoprazole-quadruple therapy for cure of Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti

1997
Immediate repeat course of amoxycillin, metronidazole and omeprazole to eradicate Helicobacter pylori.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:2

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Femal

1997
Does pretreatment with omeprazole decrease the chance of eradication of Helicobacter pylori in peptic ulcer patients?
    The American journal of gastroenterology, 1997, Volume: 92, Issue:5

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Schedule; Fe

1997
Bismuth subsalicylate instead of metronidazole with lansoprazole and clarithromycin for Helicobacter pylori infection: a randomized trial.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Anti-Bacterial Agents; Anti-Ulcer Agents; B

1997
Pantoprazole versus omeprazole in one-week low-dose triple therapy for curve of H. pylori infection.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidazoles; C

1997
Quadruple therapy: the golden bullet or a drug too far?
    Helicobacter, 1996, Volume: 1, Issue:2

    Topics: Antacids; Drug Therapy, Combination; Enzyme Inhibitors; Famotidine; Helicobacter Infections; Helicob

1996
Effectiveness of quadruple therapy using lansoprazole, instead of omeprazole, in curing Helicobacter pylori infection.
    Helicobacter, 1996, Volume: 1, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Antacids; Anti-Ulcer Agents; Bacterial Protein

1996
Randomized comparison of ranitidine bismuth citrate-based triple therapies for Helicobacter pylori.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:12

    Topics: Adult; Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Bismuth; Breath Test

1997
Ranitidine versus colloidal bismuth subcitrate in combination with amoxicillin and metronidazole for eradicating Helicobacter pylori in patients with duodenal ulcer.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combin

1997
One week triple therapy for Helicobacter pylori: does high-dose clarithromycin confer additional benefit?
    Helicobacter, 1997, Volume: 2, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitrichomonal Agents; Cl

1997
Sucralfate as an alternative to bismuth in quadruple therapy for Helicobacter pylori eradication.
    Helicobacter, 1997, Volume: 2, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Female; Gastritis; Helicobacter Infe

1997
Eradicate the bug before you start the drug?
    The American journal of gastroenterology, 1998, Volume: 93, Issue:2

    Topics: Antacids; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination;

1998
Eradicating Helicobacter pylori reduces hypergastrinaemia during long-term omeprazole treatment.
    Gut, 1998, Volume: 42, Issue:2

    Topics: Adult; Alginates; Aluminum Hydroxide; Amoxicillin; Antacids; Anti-Ulcer Agents; Drug Combinations; D

1998
Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough?
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial

1998
One-week proton pump inhibitor-based triple therapy eradicates residual Helicobacter pylori after failed dual therapy.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1998, Volume: 97, Issue:4

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Resistance, Microb

1998
Two-day quadruple therapy for cure of Helicobacter pylori infection: a comparative, randomized trial.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:6

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Administration Schedule; Fema

1998
Helicobacter pylori eradication: kill the bug and save the pill?
    The American journal of gastroenterology, 1998, Volume: 93, Issue:7

    Topics: Antacids; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bismuth; Follow-Up Studies

1998
One-week triple therapy with ranitidine bismuth citrate, clarithromycin and metronidazole versus two-week dual therapy with ranitidine bismuth citrate and clarithromycin for Helicobacter pylori infection: a randomized, clinical trial.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clari

1998
Lansoprazole quadruple therapy is effective in curing Helicobacter pylori infection.
    Helicobacter, 1998, Volume: 3, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti

1998
Cure of H. pylori infection using a 7-day triple therapy combining pantoprazole with two antibiotics.
    Helicobacter, 1998, Volume: 3, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents

1998
Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Ulcer Agents; Benzimidazoles; Clarithromy

1998
A new quadruple therapy for the eradication of Helicobacter pylori. Effect of pretreatment with omeprazole on the cure rate.
    Journal of gastroenterology, 1998, Volume: 33, Issue:5

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Dyspe

1998
[Recurrence rate of H. pylori after successful eradication and second eradication therapy after initial failure of treatment].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57, Issue:1

    Topics: Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Follow-Up Studies; Helico

1999
[Four kinds of new triple therapy regiments for Helicobacter pylori eradication in patients with peptic ulcer].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Clarithromycin

1999
[Triple therapy regimens involving H2 blockaders for therapy of Helicobacter pylori infections].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti

1999
One-week ranitidine bismuth citrate versus colloidal bismuth subcitrate-based anti-Helicobacter triple therapy: a prospective randomized controlled trial.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Administration Sche

1999
Efficacy of 7 day lansoprazole-based triple therapy for Helicobacter pylori infection in elderly patients.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Amoxicillin; Antibodies, Bacterial

1999
Comparison of two 3-day Helicobacter pylori eradication regimens with a standard 1-week regimen.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial

1999
Randomized trial of omeprazole and clarithromycin combined with either metronidazole or amoxycillin in patients with metronidazole-resistant or -susceptible Helicobacter pylori strains.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:7

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug

1999
One-week ranitidine bismuth citrate in combinations with metronidazole, amoxycillin and clarithromycin in the treatment of Helicobacter pylori infection: the RBC-MACH study.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:8

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clarithromy

1999
Prevalence of resistance to clarithromycin and its clinical impact on the efficacy of Helicobacter pylori eradication.
    Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial

1999
Helicobacter treatment with quadruple therapy in primary health care for patients with a history of ulcer disease.
    Family practice, 1999, Volume: 16, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Drug Therapy, Combinati

1999
Quadruple therapy is effective for eradicating Helicobacter pylori after failure of triple proton-pump inhibitor-based therapy: a detailed, prospective analysis of 21 consecutive cases.
    Helicobacter, 1999, Volume: 4, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Clarithromycin; Drug Re

1999
Eradication of Helicobacter pylori using 30 mg or 60 mg lansoprazole combined with amoxicillin and metronidazole: one and two weeks of a new triple therapy.
    Journal of gastroenterology, 1999, Volume: 34 Suppl 11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

1999
Effect of Helicobacter pylori eradication on peptic ulcer disease complicated with outlet obstruction.
    Helicobacter, 2000, Volume: 5, Issue:1

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy,

2000
Importance of Helicobacter pylori cagA and vacA status for the efficacy of antibiotic treatment.
    Gut, 2000, Volume: 46, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti

2000
Pharmacokinetics of clarithromycin in Helicobacter pylori eradication therapy in patients with liver cirrhosis.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromy

2000
Intravenous eradication therapy for bleeding gastroduodenal ulcer associated with Helicobacter pylori infection.
    Revista espanola de enfermedades digestivas, 2000, Volume: 92, Issue:6

    Topics: Adult; Aged; Ampicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Schedule; Fem

2000
Third line treatment for Helicobacter pylori: a prospective, culture-guided study in peptic ulcer patients.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:10

    Topics: Adult; Aged; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Double-Blind Method; Female; Follo

2000
Influence of Helicobacter pylori eradication therapy on 13C aminopyrine breath test: comparison among omeprazole-, lansoprazole-, or pantoprazole-containing regimens.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aminopyrine; Anti-Ulcer Agents; Benzimidazoles

2000
The effect of culture results for Helicobacter pylori on the choice of treatment following failure of initial eradication.
    The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ul

2001
Modified seven-day, quadruple therapy as a first line Helicobacter pylori treatment.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:7

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Sch

2001
Ranitidine bismuth citrate with clarithromycin alone or with metronidazole for the eradication of Helicobacter pylori.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:8

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Breath Tests; Carbon Isotopes; Clari

2001
Various durations of a standard regimen (amoxycillin, metronidazole, colloidal bismuth sub-citrate for 2 weeks or with additional ranitidine for 1 or 2 weeks) on eradication of Helicobacter pylori in Iranian peptic ulcer patients. A randomized controlled
    European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:8

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Biopsy, Needle; Bismuth; Breath Tests; Drug Administratio

2001
[Efficiency of quamatel in combination with device sound stimulation of the gastroduodenal zone in ulcer patients].
    Klinicheskaia meditsina, 2001, Volume: 79, Issue:8

    Topics: Acoustic Stimulation; Adolescent; Adult; Amoxicillin; Anti-Ulcer Agents; Antifungal Agents; Combined

2001
Helicobacter pylori eradication therapy is more effective in peptic ulcer than in non-ulcer dyspepsia.
    European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:11

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clarithromycin; Dyspepsia; Female; H

2001
Clinical outcome and influencing factors of a new short-term quadruple therapy for Helicobacter pylori eradication: a randomized controlled trial (MACLOR study).
    Archives of internal medicine, 2002, Jan-28, Volume: 162, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2002
[Treatment of duodenal peptic ulcer with metronidazole].
    Voenno-meditsinskii zhurnal, 1977, Issue:8

    Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Duodenal Ul

1977
Metronidazole versus cimetidine in treatment of gastroduodenal ulcer.
    Lancet (London, England), 1986, Apr-19, Volume: 1, Issue:8486

    Topics: Cimetidine; Clinical Trials as Topic; Female; Humans; Male; Metronidazole; Middle Aged; Peptic Ulcer

1986

Other Studies

114 other studies available for metronidazole and Gastroduodenal Ulcer

ArticleYear
Effects of Quadruple Therapy Combined with Probiotics on
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: Amoxicillin; Anti-Bacterial Agents; Bismuth; Drug Therapy, Combination; Gastrins; Helicobacter Infec

2022
Antibiotic Resistance of
    Medicina (Kaunas, Lithuania), 2022, Dec-20, Volume: 59, Issue:1

    Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Cross-Sectional Studies; Drug

2022
Antibiotic resistance of Helicobacter pylori infection in a children's hospital in Vietnam: prevalence and associated factors.
    Minerva medica, 2020, Volume: 111, Issue:5

    Topics: Amoxicillin; Child; Child, Preschool; Clarithromycin; Drug Resistance, Microbial; Drug Therapy, Comb

2020
Clinical factors associated with initial Helicobacter pylori eradication therapy: a retrospective study in China.
    Scientific reports, 2020, 09-21, Volume: 10, Issue:1

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Clarithromycin; Dr

2020
Antimicrobial Resistance and the Successful Eradication of
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2021, Volume: 75, Issue:2

    Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Asian People; Child; Child, Preschool; Clarithromyci

2021
Pilot study: miscellaneous therapy is highly successful for Helicobacter pylori eradication.
    Alimentary pharmacology & therapeutics, 2013, Volume: 37, Issue:12

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Female; Gastri

2013
What is the impact of Helicobacter pylori density on the success of eradication therapy: a clinico-histopathological study.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents; Breath Tests; Case-Control Studies; Cla

2013
[Guidelines for the diagnosis and treatment of Helicobacter pylori infection in Korea, 2013 revised edition].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2013, Volume: 62, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Aspirin; Bismuth; Breath Tests; Clarithromycin; Gastroesophageal

2013
[Progress in the treatment of Helicobacter pylori infection].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2014, Volume: 39, Issue:9

    Topics: Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Drugs, Chinese Herbal; Gastritis;

2014
The efficacy of moxifloxacin-containing triple therapy after standard triple, sequential, or concomitant therapy failure for Helicobacter pylori eradication in Korea.
    Gut and liver, 2014, Volume: 8, Issue:6

    Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Cohort Studies; Drug Ther

2014
A 15-year-old boy with abdominal pain, growth retardation, and anemia secondary to Helicobacter pylori-associated peptic ulcer.
    Pediatric annals, 2015, Volume: 44, Issue:3

    Topics: Adolescent; Amoxicillin; Anemia, Iron-Deficiency; Clarithromycin; Drug Therapy, Combination; Growth

2015
Susceptibility of Helicobacter pylori to antibiotics in Chinese patients.
    Journal of digestive diseases, 2015, Volume: 16, Issue:8

    Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Clarithromycin; Drug Resistance, Bacterial; Drug

2015
A high-throughput multiplex genetic detection system for Helicobacter pylori identification, virulence and resistance analysis.
    Future microbiology, 2016, Volume: 11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Base Sequence; Biopsy; China; DNA Mutational

2016
Antibiotic susceptibility patterns in Helicobacter pylori strains from patients with upper gastrointestinal pathology in western Nigeria.
    British journal of biomedical science, 2009, Volume: 66, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Biopsy; Ciprofloxacin; Clarithromycin; DNA, Bacterial; Drug Resi

2009
Helicobacter pylori infection in patients with chronic urticaria: correlation with pathologic findings in gastric biopsies.
    International journal of dermatology, 2009, Volume: 48, Issue:5

    Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Biopsy; Case-Control Studies; Chronic Disease; Fema

2009
Drug resistance pattern and clonality in H. pylori strains.
    Journal of infection in developing countries, 2009, Mar-01, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents, Local; beta-Lactamases; Clarithromycin;

2009
[Diagnosis and treatment guidelines for Helicobacter pylori infection in Korea].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2009, Volume: 54, Issue:5

    Topics: Amoxicillin; Antacids; Anti-Infective Agents; Bismuth; Breath Tests; Clarithromycin; Enzyme-Linked I

2009
Characterization of multiple Helicobacter bizzozeronii isolates from a Finnish patient with severe dyspeptic symptoms and chronic active gastritis.
    Helicobacter, 2010, Volume: 15, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacteriological Techniques; Catalase; Culture Media; DNA,

2010
Effects of CYP2C19, MDR1, and interleukin 1-B gene variants on the eradication rate of Helicobacter pylori infection by triple therapy with pantoprazole, amoxicillin, and metronidazole.
    European journal of clinical pharmacology, 2010, Volume: 66, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial

2010
Primary resistance to clarithromycin, metronidazole and amoxicillin of Helicobacter pylori isolated from Tunisian patients with peptic ulcers and gastritis: a prospective multicentre study.
    Annals of clinical microbiology and antimicrobials, 2010, Aug-13, Volume: 9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Child; Child, Presch

2010
Selective immunoglobulin M deficiency in a patient with refractory giardiasis.
    Journal of investigational allergology & clinical immunology, 2010, Volume: 20, Issue:4

    Topics: Adolescent; Antiprotozoal Agents; Diarrhea; Duodenitis; Giardia lamblia; Giardiasis; Humans; Immunog

2010
Quadruple therapy with ecabet sodium, omeprazole, amoxicillin and metronidazole is effective for eradication of Helicobacter pylori after failure of first-line therapy (KDOG0201 Study).
    Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:3

    Topics: Abietanes; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combina

2010
Factors modulating the outcome of treatment for the eradication of Helicobacter pylori infection.
    The new microbiologica, 2012, Volume: 35, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Antibodies, Bacterial; Antigens, Bacterial; Bacterial P

2012
Bismuth subcitrate/metronidazole/ tetracycline--Axcan Pharma. Bismuth triple therapy--Axcan Pharma, Helicide.
    Drugs in R&D, 2002, Volume: 3, Issue:6

    Topics: Anti-Bacterial Agents; Bismuth; Drug Combinations; Helicobacter Infections; Helicobacter pylori; Hum

2002
[Association among anti-CagA antibody detection, antibiotic susceptibility, and peptic ulcer in patients with Helicobacter pylori infection].
    Enfermedades infecciosas y microbiologia clinica, 2003, Volume: 21, Issue:3

    Topics: Adult; Aged; Antibodies, Bacterial; Antibody Specificity; Antigens, Bacterial; Bacterial Proteins; C

2003
Changing pattern of antimicrobial resistance of Helicobacter pylori in Korean patients with peptic ulcer diseases.
    Journal of gastroenterology, 2003, Volume: 38, Issue:5

    Topics: Anti-Bacterial Agents; Asian People; Clarithromycin; Drug Resistance, Bacterial; Female; Helicobacte

2003
Metronidazole-resistant Helicobacter pylori is more prevalent in patients with nonulcer dyspepsia than in peptic ulcer patients in a multiethnic Asian population.
    Journal of clinical microbiology, 2003, Volume: 41, Issue:11

    Topics: Asian People; Biopsy; Drug Resistance, Bacterial; Dyspepsia; Ethnicity; Female; Helicobacter Infecti

2003
Geographical difference in antimicrobial resistance pattern of Helicobacter pylori clinical isolates from Indian patients: Multicentric study.
    Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:12

    Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Drug Resistance, Bacterial; Helic

2003
Helicobacter pylori: a historical perspective 1983-2003.
    The New Zealand medical journal, 2004, May-21, Volume: 117, Issue:1194

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; Drug Therapy, Combination; Esophagitis, Peptic

2004
[Study on metronidazole resistance to Helicobacter pylori from three populations with different ethnics in Yunnan].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2004, Volume: 25, Issue:11

    Topics: Adult; China; Chronic Disease; Drug Resistance, Bacterial; Female; Gastritis; Helicobacter Infection

2004
[The trend of eradication rates of second-line quadruple therapy containing metronidazole for Helicobacter pylori infection: an analysis of recent eight years].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2005, Volume: 46, Issue:2

    Topics: Adult; Antacids; Anti-Infective Agents; Bismuth; Drug Therapy, Combination; Female; Helicobacter Inf

2005
[Prevalence of Helicobacter pylori resistant to clarithromycin, amoxicillin and metronidazole in children].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2004, Volume: 42, Issue:10

    Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Child; Child, Preschool; Clarithromycin; Drug Resist

2004
Mutation discovery in bacterial genomes: metronidazole resistance in Helicobacter pylori.
    Nature methods, 2005, Volume: 2, Issue:12

    Topics: Anti-Infective Agents; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Bacterial; Genome, Bacte

2005
Tetracycline, metronidazole and amoxicillin-metronidazole combinations in proton pump inhibitor-based triple therapies are equally effective as alternative therapies against Helicobacter pylori infection.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:1 Pt 2

    Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Female; Gastritis; He

2006
[Medical, social, and economic effectiveness of treatment of day-case patients with peptic ulcer].
    Klinicheskaia meditsina, 2006, Volume: 84, Issue:1

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Clarithromycin; Cost-Benefit An

2006
Prospective multicentre study on antibiotic resistance of Helicobacter pylori strains obtained from children living in Europe.
    Gut, 2006, Volume: 55, Issue:12

    Topics: Adolescent; Age Distribution; Amoxicillin; Anti-Infective Agents; Child; Child, Preschool; Clarithro

2006
Helicobacter pylori antibiotic resistance in a Dutch region: trends over time.
    The Netherlands journal of medicine, 2006, Volume: 64, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Drug Resistance, Bacteria

2006
Effect of CYP2C19*17 gene variant on Helicobacter pylori eradication in peptic ulcer patients.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Alleles; Amoxicillin; Anti-

2006
Guidelines in the medical treatment of Helicobacter pylori infection.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 3

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Clarithromycin; Dyspeps

2006
Eradication rates of helicobacter pylori infection with second-line treatment: non-ulcer dyspepsia compared to peptic ulcer disease.
    Hepato-gastroenterology, 2007, Volume: 54, Issue:76

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Dysp

2007
[Changing patterns of antibiotic resistance of Helicobacter pylori in patients with peptic ulcer disease].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2007, Volume: 50, Issue:6

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Disk Diffusion Antimicrobial Tests;

2007
Small-bowel bacterial overgrowth in the postgastrectomy syndrome.
    Scandinavian journal of gastroenterology, 1983, Volume: 18, Issue:2

    Topics: Adult; Aged; Bacteria, Aerobic; Bacteria, Anaerobic; Bacteriological Techniques; Breath Tests; Femal

1983
[Metronidazole in the treatment of peptic ulcer].
    Klinicheskaia meditsina, 1981, Volume: 59, Issue:2

    Topics: Adolescent; Adult; Aged; Duodenal Ulcer; Female; Humans; Male; Metronidazole; Middle Aged; Peptic Ul

1981
[Helicobacter pylori and peptic ulcer--1995 therapeutic indications and recommendations of a Munster Expert Group].
    Zeitschrift fur Gastroenterologie, 1995, Volume: 33, Issue:10

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Dose-Response Relationship, Drug; Dr

1995
90% cure: which anti-Helicobacter therapy can achieve this treatment goal?
    The American journal of gastroenterology, 1995, Volume: 90, Issue:9

    Topics: Amoxicillin; Bismuth; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Human

1995
Effect of Helicobacter pylori eradication on peptic ulcer healing.
    Postgraduate medical journal, 1995, Volume: 71, Issue:832

    Topics: Adult; Aged; Drug Therapy, Combination; Duodenal Ulcer; Female; Helicobacter Infections; Helicobacte

1995
Helicobacter pylori eradication and reinfection.
    Lancet (London, England), 1995, Jun-24, Volume: 345, Issue:8965

    Topics: Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori;

1995
One-week low-dose triple therapy: new standards for Helicobacter pylori treatment.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:1

    Topics: Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Helicobacter Infections; He

1995
Hitting H pylori for four.
    Lancet (London, England), 1995, Apr-01, Volume: 345, Issue:8953

    Topics: Anti-Ulcer Agents; Drug Administration Schedule; Drug Therapy, Combination; Helicobacter Infections;

1995
Effective treatment after failure of omeprazole plus amoxycillin to eradicate Helicobacter pylori infection in peptic ulcer disease.
    Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amoxicillin; Bismuth; Drug Therapy, Combinatio

1994
[10 days of triple treatment of Helicobacter pylori infection and peptic ulcer. Status after treatment of 4 weeks and of one year].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1994, Sep-10, Volume: 114, Issue:21

    Topics: Adult; Aged; Bismuth; Drug Therapy, Combination; Female; Follow-Up Studies; Helicobacter Infections;

1994
[A Norwegian conference on updating of the treatment of Helicobacter pylori in peptic ulcer. Interessegruppe for Gastroenterologi].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1994, Sep-10, Volume: 114, Issue:21

    Topics: Amoxicillin; Bismuth; Drug Therapy, Combination; Follow-Up Studies; Helicobacter Infections; Helicob

1994
Ribotyping patterns and emergence of metronidazole resistance in paired clinical samples of Helicobacter pylori.
    Journal of clinical microbiology, 1994, Volume: 32, Issue:4

    Topics: Amoxicillin; Anti-Ulcer Agents; DNA, Bacterial; DNA, Ribosomal; Drug Resistance, Microbial; Drug The

1994
Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:8

    Topics: Amoxicillin; Bismuth; Drug Therapy, Combination; Female; Gastrins; Gastritis; Helicobacter Infection

1994
Role of Helicobacter pylori eradication in the prevention of peptic ulcer bleeding relapse.
    Digestion, 1994, Volume: 55, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Bismuth; Drug Therapy, Combination; Duodenal Ulcer; Fem

1994
Helicobacter pylori infection and exaggerated gastrin release. Effects of inflammation and progastrin processing.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:8

    Topics: Adult; Bismuth; Female; Food; Gastrins; Helicobacter Infections; Helicobacter pylori; Humans; Male;

1993
[Helicobacter pylori infection and peptic ulcer].
    Deutsche medizinische Wochenschrift (1946), 1993, Dec-03, Volume: 118, Issue:48

    Topics: Amoxicillin; Bismuth; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Human

1993
One-day therapy for treatment of Helicobacter pylori infection.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:9

    Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Chronic Disease; Drug Administration Schedule; Drug Therapy,

1993
Treatment of peptic ulcers caused by Helicobacter pylori.
    The New England journal of medicine, 1993, Feb-04, Volume: 328, Issue:5

    Topics: Amoxicillin; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Metron

1993
Antimicrobial susceptibility pattern & biotyping of Helicobacter pylori isolates from patients with peptic ulcer diseases.
    The Indian journal of medical research, 1995, Volume: 102

    Topics: Adolescent; Adult; Bacterial Typing Techniques; Child; Disease Susceptibility; Drug Resistance, Micr

1995
Evaluation of a new bismuth-free triple therapy in nude mice and humans.
    European journal of gastroenterology & hepatology, 1995, Volume: 7 Suppl 1

    Topics: Amoxicillin; Animals; Anti-Ulcer Agents; Antitrichomonal Agents; Bismuth; Colony Count, Microbial; C

1995
Gastric mucosal hepatocyte growth factor in Helicobacter pylori gastritis and peptic ulcer disease.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:7

    Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Biopsy; Drug Therapy, Combination; Female; Gastric Mucosa; Ga

1996
Prevalence of metronidazole resistant Helicobacter pylori strains among Chinese peptic ulcer disease patients and normal controls in Hong Kong.
    Gut, 1996, Volume: 38, Issue:5

    Topics: Anti-Ulcer Agents; Antitrichomonal Agents; Biopsy; Case-Control Studies; China; Drug Resistance, Mic

1996
One-week triple therapy with omeprazole, amoxycillin and either clarithromycin or metronidazole for cure of Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; A

1996
An audit of low dose triple therapy for eradication of Helicobacter pylori.
    The New Zealand medical journal, 1996, Aug-09, Volume: 109, Issue:1027

    Topics: Adult; Aged; Anti-Bacterial Agents; Antitrichomonal Agents; Drug Therapy, Combination; Female; Gastr

1996
Heterogeneity in susceptibility to metronidazole among Helicobacter pylori isolates from patients with gastritis or peptic ulcer disease.
    Journal of clinical microbiology, 1996, Volume: 34, Issue:9

    Topics: Drug Resistance, Microbial; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Metroni

1996
Metronidazole, ranitidine and clarithromycin combination for treatment of Helicobacter pylori infection (modified Bazzoli's triple therapy).
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitrichomonal Agents; Clarithromycin; Drug

1996
Eradication of helicobacter pylori among patients from a primary care practice.
    The Journal of family practice, 1996, Volume: 43, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Drug Therapy, Combination; Endosco

1996
Six months' experience with a pharmacist-run Helicobacter pylori treatment clinic.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Sep-01, Volume: 53, Issue:17

    Topics: Amoxicillin; Anti-Bacterial Agents; Antitrichomonal Agents; Bismuth; Cost of Illness; Drug Therapy,

1996
Drugs for treatment of peptic ulcers.
    The Medical letter on drugs and therapeutics, 1997, Jan-03, Volume: 39, Issue:991

    Topics: Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Diarrhea; Drug Inte

1997
A one-week quadruple eradication regimen for Helicobacter pylori in routine clinical practice.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Breath Tests; Dru

1997
[Triple ranitidine therapy in Helicobacter pylori infection. Recommendation for effective, safe and cost effective combination for Helicobacter pylori eradication].
    Fortschritte der Medizin, 1996, Nov-30, Volume: 114, Issue:33

    Topics: Amoxicillin; Anti-Ulcer Agents; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Admini

1996
[Helicobacter pylori eradication: finally clarity].
    Leber, Magen, Darm, 1996, Volume: 26, Issue:6

    Topics: Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Gastritis; Helicobacter I

1996
Eradication therapy in peptic ulcer disease.
    Intensive & critical care nursing, 1997, Volume: 13, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Monitoring; Drug Therapy, Combination; Helicobacter I

1997
Identification and eradication of Helicobacter pylori in an isolated patient population.
    Military medicine, 1997, Volume: 162, Issue:7

    Topics: Amoxicillin; Bismuth; Cost Savings; Drug Therapy, Combination; Helicobacter Infections; Helicobacter

1997
Sensitivity of Helicobacter pylori to metronidazole.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1997, Volume: 6, Issue:3

    Topics: Drug Resistance, Microbial; Helicobacter Infections; Helicobacter pylori; Humans; Metronidazole; Mic

1997
Simplified 10-day bismuth triple therapy for cure of Helicobacter pylori infection: experience from clinical practice in a population with a high frequency of metronidazole resistance.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Anti-Bacterial Agents; Bismuth; Drug Administration Schedu

1998
One-week triple therapy with lansoprazole, clarithromycin, and metronidazole to cure Helicobacter pylori infection in peptic ulcer disease in Korea.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Clarithromycin; Drug Administ

1998
Helicobacter pylori and peptic ulcer disease therapies: a survey of gastroenterologists in Israel.
    Helicobacter, 1998, Volume: 3, Issue:2

    Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Health Care Surveys; Helicobacter pylori; Humans

1998
Eradication of Helicobacter pylori restores elevation of serum gastrin concentrations in patients with end-stage renal disease.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:5

    Topics: Ammonia; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Female; Gastric Juice;

1998
Assessment of symptomatic response as predictor of Helicobacter pylori status following eradication therapy in patients with ulcer.
    Gut, 1998, Volume: 42, Issue:5

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitrichomonal Agents; Breath T

1998
Four-day quadruple therapy as a routine treatment for Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer

1997
Characterization of clinical isolates of Helicobacter pylori in Singapore.
    Microbios, 1998, Volume: 94, Issue:378

    Topics: Amoxicillin; Anti-Bacterial Agents; Antigens, Bacterial; Bacterial Proteins; Bacterial Typing Techni

1998
The pharmacoeconomic impact of antimicrobial therapy for peptic ulcer disease in a large urban jail.
    Journal of urban health : bulletin of the New York Academy of Medicine, 1998, Volume: 75, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Female; Helicob

1998
One-week low-dose triple therapy is effective in treating Helicobacter pylori-infected patients with bleeding peptic ulcers.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1998, Volume: 97, Issue:11

    Topics: Adult; Aged; Clarithromycin; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal

1998
Understanding peptic ulcer disease pharmacotherapeutics.
    The Nurse practitioner, 1999, Volume: 24, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Female; Helicob

1999
Helicobacter pylori in gastric biopsies of Taiwanese patients with gastroduodenal diseases.
    Japanese journal of medical science & biology, 1998, Volume: 51, Issue:1

    Topics: ABO Blood-Group System; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigens, Bacterial;

1998
Comparative evaluation of two methods for testing metronidazole susceptibility of Helicobacter pylori in routine practice.
    Diagnostic microbiology and infectious disease, 1999, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Drug Resistance, Microbial;

1999
CYP2C19 genotype-related efficacy of omeprazole for the treatment of infection caused by Helicobacter pylori.
    Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:5

    Topics: Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Bism

1999
Symptomatic benefit 1-3 years after H. pylori eradication in ulcer patients: impact of gastroesophageal reflux disease.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:1

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Femal

2000
A single drug for Helicobacter pylori infection: first results with a new bismuth triple monocapsule.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:3

    Topics: Adult; Aged; Anti-Ulcer Agents; Capsules; Female; Gastritis; Gastroscopy; Helicobacter Infections; H

2000
Metronidazole and clarithromycin susceptibility and the subtypes of vacA of Helicobacter pylori isolates in Estonia.
    Scandinavian journal of infectious diseases, 2000, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aerobiosis; Aged; Anaerobiosis; Anti-Bacterial Agents; Bacterial Proteins; Clarit

2000
Primary and combined resistance to four antimicrobial agents in Helicobacter pylori in Sofia, Bulgaria.
    Journal of medical microbiology, 2000, Volume: 49, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bulgaria; Child; Child, Preschool; Chronic Disease;

2000
Metronidazole-resistant Helicobacter pylori in an urban Asian population.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Asia; Drug Resistance, Microbial;

2000
[Helicobacter pylori eradication in gastroduodenal ulcer: good, fine and not expensive].
    Medicina clinica, 2000, Jun-03, Volume: 115, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Cost-Benefit Analysis; Drug T

2000
[Upgrading efficiency and safety of combined antihelicobacterial treatment of ulcer patients using modern clinicopharmacological approaches].
    Klinicheskaia meditsina, 2000, Volume: 78, Issue:9

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Drug Therapy, Com

2000
Factors affecting the variation in antibiotic resistance of Helicobacter pylori over a 3-year period.
    International journal of antimicrobial agents, 2000, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Clarith

2000
Helicobacter pylori: changing patterns of ulcer disease and antibiotic resistance.
    The Medical journal of Australia, 2000, Nov-20, Volume: 173, Issue:10

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Australia; Clarit

2000
Strategy for retreatment of therapeutic failure of eradication of Helicobacter pylori infection.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2001
[Current principles of the use of laparoscopic surgery in gastroduodenal ulcer].
    Khirurgiia, 2001, Issue:6

    Topics: Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Duode

2001
Recrudescence and reinfection with Helicobacter pylori after eradication therapy in Bangladeshi adults.
    Gastroenterology, 2001, Volume: 121, Issue:4

    Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Bangladesh; Body Mass Index; Breath Tests; Carbon Isotopes; D

2001
Clarithromycin resistance of Helicobacter pylori has a major impact on the efficacy of the omeprazole-amoxicillin-clarithromycin therapy.
    Pathologie-biologie, 2001, Volume: 49, Issue:7

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Biopsy; Clarithromycin; DNA, Bacterial; Dru

2001
Six-year follow-up after successful triple therapy for Helicobacter pylori infection in patients with peptic ulcer disease.
    European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:10

    Topics: Aged; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Female; Follow-

2001
The influence of commonly prescribed synthetic drugs for peptic ulcer on the pharmacokinetic fate of glycyrrhizin from Shaoyao-Gancao-tang.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:12

    Topics: Amoxicillin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Area Under Curve;

2001
[Evolution of the sensitivity of 235 strains of Helicobacter pylori from 1995 to 1998 and impact of antibiotic treatment].
    Enfermedades infecciosas y microbiologia clinica, 2002, Volume: 20, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Resistance, Bacterial; D

2002
Metronidazole: avoid it unless it's very much indicated (avoid its routine prescription).
    The British journal of oral & maxillofacial surgery, 2002, Volume: 40, Issue:3

    Topics: Anti-Bacterial Agents; Drug Prescriptions; Drug Resistance, Bacterial; Helicobacter Infections; Heli

2002
In vitro anti-Helicobacter pylori activity of BAS-118, a new benzamide derivative.
    The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:1

    Topics: Anti-Bacterial Agents; Benzamides; Clarithromycin; Drug Resistance, Bacterial; Helicobacter Infectio

2002
[Treatment of peptic ulcer with metronidazole (clinico-experimental study)].
    Terapevticheskii arkhiv, 1976, Volume: 48, Issue:5

    Topics: Adult; Aged; Animals; Drug Evaluation; Female; Humans; Male; Metronidazole; Middle Aged; Peptic Ulce

1976
[New therapeutic developments in gastroenterology].
    Maroc medical, 1975, Volume: 55, Issue:591

    Topics: Amebiasis; Atropa belladonna; Gastrointestinal Diseases; Metronidazole; Peptic Ulcer; Phytotherapy;

1975
Eradication of Helicobacter pylori reduces gastric and duodenal ulcer recurrence.
    Gastroenterology, 1992, Volume: 103, Issue:5

    Topics: Bismuth; Helicobacter Infections; Helicobacter pylori; Humans; Metronidazole; Organometallic Compoun

1992
Triple therapy of Helicobacter pylori infection in peptic ulcer. A 12-month follow-up study of 93 patients.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:11

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Ulcer Agents; Dose-Response

1992
The role of Helicobacter pylori in the pathogenesis of acid-peptic disease.
    Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians, 1992, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Black or African American; Dyspepsia; Gastritis; Helicobac

1992
Metronidazole in acid peptic disease.
    The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:4

    Topics: Amebiasis; Antacids; Campylobacter Infections; Drug Therapy, Combination; Dyspepsia; Humans; Metroni

1990
[Morphologic change in Campylobacter pylori associated gastritis in and following successful antibacterial therapy].
    Der Pathologe, 1989, Volume: 10, Issue:1

    Topics: Amoxicillin; Bismuth; Campylobacter Infections; Drug Therapy, Combination; Gastric Mucosa; Gastritis

1989