metronidazole has been researched along with Gastritis, Familial Giant Hypertrophic in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serologic evidence of concomitant Mycoplasma pneumoniae infection was present." | 1.28 | Transient protein-losing hypertrophic gastropathy associated with Mycoplasma pneumoniae infection in childhood. ( Ben Amitai, D; Dinari, G; Garty, BZ; Zahavi, I, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Groisman, GM | 1 |
| George, J | 1 |
| Berman, D | 1 |
| Harpaz, N | 1 |
| Yamada, M | 1 |
| Sumazaki, R | 1 |
| Adachi, H | 1 |
| Ahmed, T | 1 |
| Matsubara, T | 1 |
| Hori, T | 1 |
| Nakahara, A | 1 |
| Takita, H | 1 |
| Kawasaki, M | 1 |
| Hizawa, K | 1 |
| Aoyagi, K | 1 |
| Nakamura, S | 1 |
| Fujishima, M | 1 |
| Ben Amitai, D | 1 |
| Zahavi, I | 1 |
| Dinari, G | 1 |
| Garty, BZ | 1 |
4 other studies available for metronidazole and Gastritis, Familial Giant Hypertrophic
| Article | Year |
|---|---|
Resolution of protein-losing hypertrophic lymphocytic gastritis with therapeutic eradication of Helicobacter pylori.
Topics: Amoxicillin; Bismuth; Drug Therapy, Combination; Female; Gastric Mucosa; Gastritis, Hypertrophic; He | 1994 |
Resolution of protein-losing hypertrophic gastropathy by eradication of Helicobacter pylori.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chil | 1997 |
Ménétrièr's disease associated with Helicobacter pylori infection: resolution of enlarged gastric folds and hypoproteinemia after antibacterial treatment.
Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Female; | 1997 |
Transient protein-losing hypertrophic gastropathy associated with Mycoplasma pneumoniae infection in childhood.
Topics: Amoxicillin; Antacids; Antibodies, Bacterial; Child, Preschool; Enzyme-Linked Immunosorbent Assay; G | 1992 |