Page last updated: 2024-10-31

metronidazole and Gastric Rupture

metronidazole has been researched along with Gastric Rupture in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al Rasheed, MR1
Senseng, CG1
Rao, S1
Solaymani-Mohammadi, S1
Petri, WA1
Parker, SK1
Angel, C1
Chand, N1
Sankar, A1
Rowen, J1
Murillo, C1

Reviews

1 review available for metronidazole and Gastric Rupture

ArticleYear
Sarcina ventriculi : Review of the Literature.
    Archives of pathology & laboratory medicine, 2016, Volume: 140, Issue:12

    Topics: Anti-Infective Agents; Clostridium Infections; Diagnosis, Differential; Drug Therapy, Combination; E

2016

Other Studies

2 other studies available for metronidazole and Gastric Rupture

ArticleYear
Hepatic amebiasis: a reminder of the complications.
    Current opinion in pediatrics, 2009, Volume: 21, Issue:1

    Topics: Animals; Antiprotozoal Agents; Diagnosis, Differential; Drainage; Entamoeba histolytica; Genotype; H

2009
Gastric wall erosion by an amebic liver abscess in a 3-year-old girl.
    Pediatric surgery international, 2000, Volume: 16, Issue:5-6

    Topics: Amebicides; Anti-Infective Agents; Biopsy; Cefotaxime; Cephalosporins; Chemotherapy, Adjuvant; Child

2000