Page last updated: 2024-10-31

metronidazole and Gallstones

metronidazole has been researched along with Gallstones in 6 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Gallstones: Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bari, H1
Khan, MR1
Shariff, AH1
Yanni, F1
Mekhail, P1
Morris-Stiff, G1
Choi, YJ1
Won, EJ1
Kim, SH1
Shin, MG1
Shin, JH1
Suh, SP1
Severi, C1
Zippi, M1
Baccini, F1
Gentile, G1
Bezzi, M1
Fiocca, F1
Caprilli, R1
Talwar, S1
Mathur, AK1
Prasad, P1
Oshodi, TO1
Sandison, AP1
Sheridan, WG1
Foster, ME1
Lewis, MH1

Trials

1 trial available for metronidazole and Gallstones

ArticleYear
Exploration of the common bile duct for stones: the influence of the flexible choledochoscope and perioperative antibiotic prophylaxis.
    Journal of the Royal College of Surgeons of Edinburgh, 1995, Volume: 40, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Cephalosporins; Cholangiopancreatography, Endoscopic Retrograde; Cho

1995

Other Studies

5 other studies available for metronidazole and Gallstones

ArticleYear
Antibiotics in acute calculous cholecystitis - do Tokyo guidelines influence the surgeons' practices?
    JPMA. The Journal of the Pakistan Medical Association, 2017, Volume: 67, Issue:5

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Cefazolin; Ceftriaxone; Cholecystectomy; Cholecystectomy,

2017
A selective antibiotic prophylaxis policy for laparoscopic cholecystectomy is effective in minimising infective complications.
    Annals of the Royal College of Surgeons of England, 2013, Volume: 95, Issue:5

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cephalosporins; Cholecystectomy, Laparoscopic; Cholec

2013
First Case Report of Bacteremia Due to Catabacter hongkongensis in a Korean Patient.
    Annals of laboratory medicine, 2017, Volume: 37, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Cefotaxime; Cholangiopancreatography, Endoscopic Retrograde; Gallstones

2017
Amebic liver abscess, Mirizzi syndrome, and acute hepatic failure.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:2

    Topics: Anti-Infective Agents; Barium Radioisotopes; Cefoperazone; Cholecystectomy; Diabetes Mellitus, Type

2004
Effects of metronidazole on hyperlipidaemia.
    International journal of cardiology, 2005, May-11, Volume: 101, Issue:1

    Topics: Animals; Bile; Gallstones; Hyperlipidemias; Hypolipidemic Agents; Metronidazole; Models, Animal; Rab

2005