metronidazole has been researched along with Gallstones in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Gallstones: Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bari, H | 1 |
Khan, MR | 1 |
Shariff, AH | 1 |
Yanni, F | 1 |
Mekhail, P | 1 |
Morris-Stiff, G | 1 |
Choi, YJ | 1 |
Won, EJ | 1 |
Kim, SH | 1 |
Shin, MG | 1 |
Shin, JH | 1 |
Suh, SP | 1 |
Severi, C | 1 |
Zippi, M | 1 |
Baccini, F | 1 |
Gentile, G | 1 |
Bezzi, M | 1 |
Fiocca, F | 1 |
Caprilli, R | 1 |
Talwar, S | 1 |
Mathur, AK | 1 |
Prasad, P | 1 |
Oshodi, TO | 1 |
Sandison, AP | 1 |
Sheridan, WG | 1 |
Foster, ME | 1 |
Lewis, MH | 1 |
1 trial available for metronidazole and Gallstones
Article | Year |
---|---|
Exploration of the common bile duct for stones: the influence of the flexible choledochoscope and perioperative antibiotic prophylaxis.
Topics: Adult; Aged; Aged, 80 and over; Cephalosporins; Cholangiopancreatography, Endoscopic Retrograde; Cho | 1995 |
5 other studies available for metronidazole and Gallstones
Article | Year |
---|---|
Antibiotics in acute calculous cholecystitis - do Tokyo guidelines influence the surgeons' practices?
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Cefazolin; Ceftriaxone; Cholecystectomy; Cholecystectomy, | 2017 |
A selective antibiotic prophylaxis policy for laparoscopic cholecystectomy is effective in minimising infective complications.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cephalosporins; Cholecystectomy, Laparoscopic; Cholec | 2013 |
First Case Report of Bacteremia Due to Catabacter hongkongensis in a Korean Patient.
Topics: Aged; Anti-Bacterial Agents; Cefotaxime; Cholangiopancreatography, Endoscopic Retrograde; Gallstones | 2017 |
Amebic liver abscess, Mirizzi syndrome, and acute hepatic failure.
Topics: Anti-Infective Agents; Barium Radioisotopes; Cefoperazone; Cholecystectomy; Diabetes Mellitus, Type | 2004 |
Effects of metronidazole on hyperlipidaemia.
Topics: Animals; Bile; Gallstones; Hyperlipidemias; Hypolipidemic Agents; Metronidazole; Models, Animal; Rab | 2005 |