Page last updated: 2024-10-31

metronidazole and Foreign Bodies

metronidazole has been researched along with Foreign Bodies in 7 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Foreign Bodies: Inanimate objects that become enclosed in the body.

Research Excerpts

ExcerptRelevanceReference
"The brain stem is an uncommon site of a brain abscess."2.41Management of brain stem abscess. ( Bouillot, P; Choux, M; Fuentes, S; Lena, G; Regis, J, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Allam, M1
Pericleous, S1
Shachor-Meyouhas, Y1
Guilburd, JN1
Kassis, I1
Ellis, AE1
Brown, CA1
Miller, DL1
Agarwal, A1
Gergits, F1
Isaacson, G1
Fuentes, S1
Bouillot, P1
Regis, J1
Lena, G1
Choux, M1
Sethi, DS1
Chew, CT1
Schneider, GT1
Geary, WL1

Reviews

2 reviews available for metronidazole and Foreign Bodies

ArticleYear
Metastatic intracranial abscesses of bronchopulmonary origin.
    The Pediatric infectious disease journal, 2003, Volume: 22, Issue:3

    Topics: Brain Abscess; Bronchi; Bronchoscopy; Ceftriaxone; Child, Preschool; Contrast Media; Drug Therapy, C

2003
Management of brain stem abscess.
    British journal of neurosurgery, 2001, Volume: 15, Issue:1

    Topics: Amoxicillin; Brain Abscess; Brain Stem; Bronchi; Cefotaxime; Child, Preschool; Drainage; Drug Therap

2001

Other Studies

5 other studies available for metronidazole and Foreign Bodies

ArticleYear
Migrated fish bone induced liver abscess: medical management.
    The Pan African medical journal, 2020, Volume: 36

    Topics: Abdominal Pain; Animals; Anti-Bacterial Agents; Bone and Bones; Diagnosis, Differential; Drug Therap

2020
Brain abscess complicating foreign body aspiration.
    The Israel Medical Association journal : IMAJ, 2009, Volume: 11, Issue:9

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Brain Abscess; Bronchi; Ceftriaxone; Child, Preschool;

2009
Diagnostic exercise: chronic vomiting in a dog.
    Veterinary pathology, 2010, Volume: 47, Issue:5

    Topics: Animals; Antiprotozoal Agents; Biopsy; Cryptosporidiosis; Cryptosporidium; Diagnosis, Differential;

2010
Retropharyngeal abscess--the foreign body connection.
    Annals of the Academy of Medicine, Singapore, 1991, Volume: 20, Issue:5

    Topics: Abscess; Adult; Aged; Airway Obstruction; Female; Foreign Bodies; Humans; Male; Metronidazole; Middl

1991
Vaginitis in adolescent girls.
    Clinical obstetrics and gynecology, 1971, Volume: 14, Issue:4

    Topics: Adolescent; Boric Acids; Candida; Candidiasis, Vulvovaginal; Child; Enterobius; Female; Foreign Bodi

1971