metronidazole has been researched along with Fever of Unknown Origin in 11 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Fever of Unknown Origin: Fever in which the etiology cannot be ascertained.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with metronidazole and tetracycline resulted in rapid clinical improvement in all except one patient." | 5.26 | Ameobic liver abscess presenting as fever of unknown origin (FUO). Serology, isotope scanning and metronidazole therapy in diagnosis and treatment. ( Farid, Z; Kilpatrick, ME; Trabolsi, B; Watten, RH; Yassin, WM, 1982) |
| "Treatment with metronidazole and tetracycline resulted in rapid clinical improvement in all except one patient." | 1.26 | Ameobic liver abscess presenting as fever of unknown origin (FUO). Serology, isotope scanning and metronidazole therapy in diagnosis and treatment. ( Farid, Z; Kilpatrick, ME; Trabolsi, B; Watten, RH; Yassin, WM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roland, T | 1 |
| Yildiz, H | 1 |
| Vandercam, B | 1 |
| Pothen, L | 1 |
| Saxena, S | 1 |
| Dwivedi, M | 1 |
| Batra, P | 1 |
| Dutta, R | 1 |
| Fitzner, S | 1 |
| Seiger, J | 1 |
| Landwehr, P | 1 |
| Meier, PN | 1 |
| Weiss, T | 1 |
| Wohlfart, J | 1 |
| Kreft, B | 1 |
| Oehme, A | 1 |
| Lübbert, C | 1 |
| Marsch, WC | 1 |
| Kekulé, AS | 1 |
| Prakash, A | 1 |
| Singh, NP | 1 |
| Makhija, A | 1 |
| Garg, D | 1 |
| Kubba, S | 1 |
| Agarwal, SK | 1 |
| Farid, Z | 1 |
| Trabolsi, B | 1 |
| Kilpatrick, ME | 1 |
| Yassin, WM | 1 |
| Watten, RH | 1 |
| Ewig, S | 1 |
| Schaal, KP | 1 |
| Steudel, A | 1 |
| Nikorowitsch, R | 1 |
| von Kempis, J | 1 |
| Staib, P | 1 |
| Vaupel, HA | 1 |
| Siminoski, K | 1 |
| Bettschen, HU | 1 |
| Merkle, A | 1 |
| Hess, T | 1 |
| Ewals, JA | 1 |
| de Geus, A | 1 |
| Zajdowicz, TR | 1 |
1 review available for metronidazole and Fever of Unknown Origin
| Article | Year |
|---|---|
Persistent fever due to occult dental infection: case report and review.
Topics: Erythromycin; Female; Fever of Unknown Origin; Humans; Metronidazole; Middle Aged; Periodontal Absce | 1993 |
10 other studies available for metronidazole and Fever of Unknown Origin
| Article | Year |
|---|---|
Persistent fever and right hypochondrium pain.
Topics: Abdominal Pain; Adult; Antiprotozoal Agents; Drainage; Dysentery, Amebic; Entamoeba histolytica; Ent | 2017 |
Fever of unknown origin attributable to haematocolpos infected with Salmonella enterica Serotypetyphi resistant to nalidixic acid: a case report.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Child; Ciprofloxacin; Diagnosis, Differen | 2013 |
[Fever and right upper abdominal pain in a 26-year-old returning from travel abroad].
Topics: Abdominal Pain; Adult; Amebicides; Ampicillin; Drug Therapy, Combination; Entamoeba histolytica; Fev | 2014 |
[37-year old patient with fever, diarrhea and lymphadenopathy].
Topics: Adult; AIDS Serodiagnosis; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antifungal | 2010 |
Mediastinitis presenting as pyrexia of unknown origin.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Female; Fever of Unknown Origin; Humans; | 2003 |
Ameobic liver abscess presenting as fever of unknown origin (FUO). Serology, isotope scanning and metronidazole therapy in diagnosis and treatment.
Topics: Adolescent; Adult; Counterimmunoelectrophoresis; Fever of Unknown Origin; Humans; Liver Abscess, Ame | 1982 |
[42-year-old patient with fever and a palpable abdominal tumor].
Topics: Abscess; Actinomycosis; Adult; Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Clavulanic Acids | 1993 |
[Fever and non-specific general symptoms].
Topics: Adult; Diagnosis, Differential; Fever of Unknown Origin; Humans; Liver Abscess, Amebic; Male; Metron | 1991 |
[Unexplained fever with spontaneous recovery in a patient who visited the tropics].
Topics: Antibodies, Protozoan; Enzyme-Linked Immunosorbent Assay; Fever of Unknown Origin; Humans; Liver Abs | 1988 |
Amebic liver abscess: the unconsidered and undiagnosed mimic.
Topics: Abdomen, Acute; Adult; Diagnosis, Differential; Fever of Unknown Origin; Humans; Liver Abscess, Ameb | 1986 |