metronidazole has been researched along with Fasciolopsiasis in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Praziquantel administered at a dosage of 10 mg/kg of body weight/day for 14 days eliminated a fluke infection in a red-billed toucan." | 1.27 | Treatment of flukes in a toucan. ( Giddings, RF, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El Nokrashy, A | 1 |
| Abou Samra, W | 1 |
| Sobeih, D | 1 |
| Lamin, A | 1 |
| Hashish, A | 1 |
| Tarshouby, S | 1 |
| Lightman, S | 1 |
| Sewelam, A | 1 |
| Taylor, M | 1 |
| Pillai, G | 1 |
| Kvalsvig, JD | 1 |
| Giddings, RF | 1 |
| Most, H | 1 |
1 review available for metronidazole and Fasciolopsiasis
| Article | Year |
|---|---|
Drug therapy. Treatment of common parasitic infections of man encountered in the United States. 2.
Topics: Amebiasis; Amebicides; Anthelmintics; Antimalarials; Antimony; Benzenesulfonates; Chloroquine; Clono | 1972 |
3 other studies available for metronidazole and Fasciolopsiasis
| Article | Year |
|---|---|
Treatment of presumed trematode-induced granulomatous anterior uveitis among children in rural areas of Egypt.
Topics: Adolescent; Animals; Antiprotozoal Agents; Child; Child, Preschool; Combined Modality Therapy; Corne | 2019 |
Targeted chemotherapy for parasite infestations in rural black preschool children.
Topics: Albendazole; Antiparasitic Agents; Black or African American; Black People; Cestode Infections; Chil | 1995 |
Treatment of flukes in a toucan.
Topics: Animals; Bird Diseases; Birds; Giardiasis; Metronidazole; Praziquantel; Trematode Infections | 1988 |