metronidazole has been researched along with Fascioliasis in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Fascioliasis: Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.
Excerpt | Relevance | Reference |
---|---|---|
"Treatment with praziquantel followed by metronidazole and tinidazole reduced abnormalities in the liver and eosinophilia." | 1.36 | A case of probable mixed-infection with Clonorchis sinensis and Fasciola sp.: CT and parasitological findings. ( Choi, WH; Chu, JP; Kim, JJ; Kim, TY; Lee, YS; Oh, IH; Song, HO; Yun, JH, 2010) |
"Human fascioliasis has been recently become a health problem in Alexandria and Dakahlia governorates." | 1.29 | A case of human fascioliasis in Qualyobia Governorate. ( Arafa, MM; Lashen, AH, 1993) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (50.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kim, TY | 1 |
Lee, YS | 1 |
Yun, JH | 1 |
Kim, JJ | 1 |
Choi, WH | 1 |
Oh, IH | 1 |
Song, HO | 1 |
Chu, JP | 1 |
Mansour-Ghanaei, F | 1 |
Shafaghi, A | 1 |
Fallah, M | 1 |
Wahn, V | 1 |
Mehlhorn, H | 1 |
Arafa, MM | 1 |
Lashen, AH | 1 |
Nik-Akhtar, B | 1 |
Tabibi, V | 1 |
Perry, W | 1 |
Goldsmid, JM | 1 |
Gelfand, M | 1 |
6 other studies available for metronidazole and Fascioliasis
Article | Year |
---|---|
A case of probable mixed-infection with Clonorchis sinensis and Fasciola sp.: CT and parasitological findings.
Topics: Adult; Animals; Anthelmintics; Antibodies, Protozoan; Clonorchiasis; Clonorchis sinensis; Entamoeba | 2010 |
The effect of metronidazole in treating human fascioliasis.
Topics: Adult; Anthelmintics; Antitrichomonal Agents; Benzimidazoles; Enzyme-Linked Immunosorbent Assay; Fas | 2003 |
[Four kinds of parasites in an 8-year-old boy. Therapeutic effects of praziquantel against Fasciola hepatica].
Topics: Ascariasis; Child; Entamoeba histolytica; Entamoebiasis; Fasciola hepatica; Fascioliasis; Feces; Gia | 1984 |
A case of human fascioliasis in Qualyobia Governorate.
Topics: Adult; Colon, Sigmoid; Egypt; Fascioliasis; Humans; Male; Metronidazole; Sigmoidoscopy | 1993 |
Metronidazole in fascioliasis: report of four cases.
Topics: Adult; Child; Fasciola hepatica; Fascioliasis; Female; Humans; Male; Metronidazole; Middle Aged | 1977 |
Human fascioliasis in Rhodesia. Report of a case with a liver abscess.
Topics: Abdomen; Biopsy; Child; Drainage; Emetine; Fasciola; Fascioliasis; Female; Humans; Liver; Liver Absc | 1972 |