metronidazole has been researched along with Facial Dermatoses in 44 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Facial Dermatoses: Skin diseases involving the FACE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with metronidazole resulted in complete clearance of the lesion." | 5.31 | HIV seronegative eosinophilic pustular folliculitis successfully treated with metronidazole. ( Hayakawa, J; Inaoka, M; Shiohara, T, 2002) |
| "Metronidazole gel was generally tolerated well during the study." | 2.71 | Is topical metronidazole effective in seborrheic dermatitis? A double-blind study. ( Altinyazar, HC; Eştürk, E; Koca, R, 2003) |
| "Rosacea is a common chronic facial skin disease." | 1.48 | Clinical characteristics and management of patients with rosacea in a tertiary dermatology center in Singapore from 2009 to 2013. ( Chan, R; Cheong, KW; Lai, YC; Yew, YW, 2018) |
| "Rosacea is a common dermatosis that can involve the bald area of the scalp." | 1.38 | [Acantholytic rosacea of the forehead and scalp in a patient with Hailey-Hailey disease]. ( Cribier, B; Kanter, P; Lipsker, D; Mohr, M, 2012) |
| "Perioral dermatitis is a relatively important and often enigmatic type of eczema." | 1.35 | Periorificial dermatitis in children: an update and description of a child with striking features. ( Cruz, MA; Kihiczak, GG; Schwartz, RA, 2009) |
| "Rosacea is a common, chronic facial dermatosis that may present in varying manners." | 1.33 | Diagnosing and managing the patient with rosacea. ( Mackley, CL; Thiboutot, DM, 2005) |
| "Treatment with metronidazole resulted in complete clearance of the lesion." | 1.31 | HIV seronegative eosinophilic pustular folliculitis successfully treated with metronidazole. ( Hayakawa, J; Inaoka, M; Shiohara, T, 2002) |
| "A 55-yr-old man with ileocolic Crohn's disease developed granulomatous dermatitis in the malar region." | 1.27 | Cutaneous metastatic Crohn's disease: treatment with metronidazole. ( Bai, JC; Boerr, LA; Kowalczuk, A; Moran, CE; Olivares, L, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (13.64) | 18.7374 |
| 1990's | 8 (18.18) | 18.2507 |
| 2000's | 17 (38.64) | 29.6817 |
| 2010's | 11 (25.00) | 24.3611 |
| 2020's | 2 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Krispinsky, A | 1 |
| Zirwas, M | 1 |
| Neema, S | 1 |
| Subramaniyan, R | 1 |
| Kinra, P | 1 |
| Hedberg, ML | 1 |
| Chibnall, RJ | 1 |
| Compton, LA | 1 |
| Cheong, KW | 1 |
| Yew, YW | 1 |
| Lai, YC | 1 |
| Chan, R | 1 |
| Kostaki, M | 1 |
| Polydorou, D | 1 |
| Adamou, E | 1 |
| Chasapi, V | 1 |
| Antoniou, C | 1 |
| Stratigos, A | 1 |
| Prieto Herman Reinehr, C | 1 |
| Kalil, CLPV | 1 |
| Bakos, RM | 1 |
| Parke, L | 1 |
| Diernaes, J | 1 |
| Bygum, A | 1 |
| Kim, KE | 1 |
| Park, TJ | 1 |
| Son, SW | 1 |
| Kim, IH | 1 |
| Moon, HR | 1 |
| Nomura, H | 1 |
| Egami, S | 1 |
| Kasai, H | 1 |
| Yokoyama, T | 1 |
| Fujimoto, A | 1 |
| Sugiura, M | 1 |
| Sattler, EC | 1 |
| Hoffmann, VS | 1 |
| Ruzicka, T | 1 |
| Braunmühl, TV | 1 |
| Berking, C | 1 |
| Lee, GL | 1 |
| Zirwas, MJ | 1 |
| Madsen, JT | 1 |
| Lorentzen, HF | 1 |
| Paulsen, E | 1 |
| Kihiczak, GG | 1 |
| Cruz, MA | 1 |
| Schwartz, RA | 1 |
| Palomo, A | 1 |
| Cervigón, I | 1 |
| Torres-Iglesias, LM | 1 |
| Mahfoudh, A | 1 |
| Khaled, A | 1 |
| Fazaa, B | 1 |
| Karaoui, S | 1 |
| Goucha, S | 1 |
| Kamoun, M | 1 |
| Mohr, M | 1 |
| Kanter, P | 1 |
| Cribier, B | 1 |
| Lipsker, D | 1 |
| Koca, R | 1 |
| Altinyazar, HC | 1 |
| Eştürk, E | 1 |
| Schaller, M | 1 |
| Sander, CA | 1 |
| Plewig, G | 1 |
| El-Shazly, AM | 1 |
| Hassan, AA | 1 |
| Soliman, M | 1 |
| Morsy, GH | 1 |
| Morsy, TA | 1 |
| Ballestero-Díez, M | 1 |
| Daudén, E | 1 |
| Ruíz-Genao, DP | 1 |
| Fraga, J | 1 |
| García-Díez, A | 1 |
| Fichtel, JC | 1 |
| Wiggins, AK | 1 |
| Lesher, JL | 1 |
| Utikal, J | 1 |
| Poenitz, N | 1 |
| Kurzen, H | 1 |
| Goerdt, S | 1 |
| Mackley, CL | 1 |
| Thiboutot, DM | 1 |
| Chamlin, SL | 1 |
| Cox, ES | 1 |
| Shannon, AB | 1 |
| Aydogan, K | 1 |
| Alver, O | 1 |
| Tore, O | 1 |
| Karadogan, SK | 1 |
| Boutli, F | 1 |
| Delli, FS | 1 |
| Mourellou, O | 1 |
| Seckin, D | 1 |
| Gurbuz, O | 1 |
| Akin, O | 1 |
| Babaiants, RS | 1 |
| Il'inskaia, AV | 1 |
| Gromova, SA | 1 |
| Samgin, MA | 1 |
| Iastrebova, RI | 1 |
| Dovzhanskiĭ, SI | 1 |
| Grashkina, IG | 1 |
| Iaksanova, EM | 1 |
| Hoekzema, R | 1 |
| Hulsebosch, HJ | 1 |
| Bos, JD | 1 |
| Hogan, DJ | 1 |
| Miller, SR | 1 |
| Shalita, AR | 1 |
| Vincenzi, C | 1 |
| Lucente, P | 1 |
| Ricci, C | 1 |
| Tosti, A | 1 |
| Sixou, JL | 1 |
| Robert, JC | 1 |
| Bonnaure-Mallet, M | 1 |
| Grossmann, B | 1 |
| Jung, K | 1 |
| Linse, R | 1 |
| Inaoka, M | 1 |
| Hayakawa, J | 1 |
| Shiohara, T | 1 |
| Baima, B | 1 |
| Sticherling, M | 1 |
| Stieger, M | 1 |
| Manders, SM | 1 |
| Lucky, AW | 1 |
| Tur, E | 1 |
| Ryatt, KS | 1 |
| Maibach, HI | 1 |
| Lowe, NJ | 1 |
| Henderson, T | 1 |
| Millikan, LE | 1 |
| Smith, S | 1 |
| Turk, K | 1 |
| Parker, F | 1 |
| Mirtschink, S | 1 |
| Barth, J | 1 |
| Hübner, U | 1 |
| Boerr, LA | 1 |
| Bai, JC | 1 |
| Olivares, L | 1 |
| Moran, CE | 1 |
| Kowalczuk, A | 1 |
4 reviews available for metronidazole and Facial Dermatoses
| Article | Year |
|---|---|
Symptomatic vulvar demodicosis: A case report and review of the literature.
Topics: Administration, Oral; Administration, Topical; Adult; Animals; Antiparasitic Agents; Antiprotozoal A | 2020 |
Granulomatous Rosacea and Periorificial Dermatitis: Controversies and Review of Management and Treatment.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Benzoyl Peroxide; Dermatitis, Perioral; Dermatologic | 2015 |
Perioral dermatitis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Child; Dermatitis; Diagnosis, Differential; Facial Dermatoses; | 1995 |
Demodicidosis revisited.
Topics: Adult; Age Distribution; Animals; Biopsy, Needle; Child; Child, Preschool; Diagnosis, Differential; | 2002 |
4 trials available for metronidazole and Facial Dermatoses
| Article | Year |
|---|---|
Is topical metronidazole effective in seborrheic dermatitis? A double-blind study.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Dermatitis, Seborrheic; Double-Blind Method; | 2003 |
Treatment of human Demodex folliculorum by camphor oil and metronidazole.
Topics: Adolescent; Adult; Animals; Antitrichomonal Agents; Child; Cinnamomum camphora; Facial Dermatoses; F | 2004 |
Metronidazole 0.75% gel vs. ketoconazole 2% cream in the treatment of facial seborrheic dermatitis: a randomized, double-blind study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Chi-Squar | 2007 |
Topical metronidazole for severe and recalcitrant rosacea: a prospective open trial.
Topics: Administration, Topical; Adult; Aged; Clinical Trials as Topic; Facial Dermatoses; Female; Humans; M | 1989 |
36 other studies available for metronidazole and Facial Dermatoses
| Article | Year |
|---|---|
Nodular Demodicosis in a Pregnant Woman Treated with Oral Ivermectin and Metronidazole.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Antiparasitic Agents; Drug Therapy, Combination; | 2019 |
Demodex induced facial frictional melanoses.
Topics: Anti-Infective Agents; Antiparasitic Agents; Drug Therapy, Combination; Facial Dermatoses; Female; F | 2020 |
Clinical characteristics and management of patients with rosacea in a tertiary dermatology center in Singapore from 2009 to 2013.
Topics: Adult; Age Distribution; Aged; Anti-Infective Agents; Cohort Studies; Databases, Factual; Disease Ma | 2018 |
Acute localized exanthematous pustulosis due to metronidazole.
Topics: Acute Generalized Exanthematous Pustulosis; Aged; Anti-Bacterial Agents; Facial Dermatoses; Humans; | 2019 |
Unusual case of rosacea fulminans after topical metronidazole application.
Topics: Administration, Cutaneous; Adult; Drug Therapy, Combination; Facial Dermatoses; Female; Humans; Isot | 2019 |
Papulopustular Facial Eruption in a Child: A Quiz.
Topics: Administration, Oral; Administration, Topical; Child, Preschool; Dermatitis, Perioral; Diagnosis, Di | 2019 |
Fiberglass-induced granulomatous periorificial dermatitis.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Biopsy; Dermatitis, Contact; Dermatitis, Occ | 2019 |
A patient with lupus miliaris disseminatus faciei treated successfully with a combination of oral metronidazole and topical tacrolimus.
Topics: Administration, Oral; Administration, Topical; Adult; Anti-Infective Agents; Drug Therapy, Combinati | 2014 |
Reflectance confocal microscopy for monitoring the density of Demodex mites in patients with rosacea before and after treatment.
Topics: Adult; Aged; Animals; Anti-Infective Agents; Doxycycline; Drug Therapy, Combination; Facial Dermatos | 2015 |
Contact sensitization to metronidazole from possible occupational exposure.
Topics: Administration, Topical; Adult; Aged; Carcinoma, Basal Cell; Dermatitis, Allergic Contact; Dermatiti | 2009 |
Periorificial dermatitis in children: an update and description of a child with striking features.
Topics: Administration, Cutaneous; Anti-Infective Agents; Child; Dermatitis, Perioral; Diagnosis, Differenti | 2009 |
[Symptomatic perioral, perinasal, and periocular papules].
Topics: Child; Dermatitis, Perioral; Diagnosis, Differential; Facial Dermatoses; Female; Granuloma; Humans; | 2009 |
[Disseminated miliary lupus of the face].
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Diagnosis, Differential; Doxycycline; Drug Ther | 2010 |
[Acantholytic rosacea of the forehead and scalp in a patient with Hailey-Hailey disease].
Topics: Acantholysis; Administration, Oral; Administration, Topical; Alopecia; Anti-Bacterial Agents; Anti-I | 2012 |
Demodex abscesses: clinical and therapeutic challenges.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Diagnosis, Differential; Erythema; Facial Derm | 2003 |
Presence of Demodex in follicular hyperkeratotic spicules on the face. A casual association?
Topics: Aged; Animals; Anti-Infective Agents; Facial Dermatoses; Female; Hair Follicle; Humans; Keratosis; M | 2004 |
Plaque-forming demodicidosis.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Antiparasitic Agents; Facial Dermatoses; Female; | 2005 |
[Persistent facial erythema and edema].
Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Diagnosis, Differential; Edem | 2005 |
Diagnosing and managing the patient with rosacea.
Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Drug Administration Routes; Faci | 2005 |
A 9-year-old boy with facial lesions.
Topics: Anti-Bacterial Agents; Child; Diagnosis, Differential; Erythromycin; Facial Dermatoses; Granulomatos | 2005 |
Papular facial eruption in an African American adolescent.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Anti-Bacterial Agents; Diagnosis, Diffe | 2006 |
Facial abscess-like conglomerates associated with Demodex mites.
Topics: Abscess; Adult; Facial Dermatoses; Humans; Male; Metronidazole; Mite Infestations | 2006 |
Demodicidosis as spinulosis of the face: a therapeutic challenge.
Topics: Aged; Anti-Infective Agents; Combined Modality Therapy; Facial Dermatoses; Humans; Hydroxyurea; Low- | 2007 |
[Metronidazole in the treatment of rosacea and perioral dermatitis].
Topics: Adult; Aged; Facial Dermatoses; Female; Humans; Male; Metronidazole; Middle Aged; Mouth; Rosacea | 1983 |
[Pathogenesis and treatment of rosacea and perioral dermatitis].
Topics: Adolescent; Adult; Aged; Calcium Gluconate; Drug Therapy, Combination; Facial Dermatoses; Female; Ga | 1980 |
Demodicidosis or rosacea: what did we treat?
Topics: Aged; Animals; Diagnosis, Differential; Facial Dermatoses; Humans; Male; Metronidazole; Mite Infesta | 1995 |
Topical metronidazole gel (0.75%) for the treatment of perioral dermatitis in children.
Topics: Administration, Cutaneous; Child; Facial Dermatoses; Female; Gels; Humans; Metronidazole; Time Facto | 1994 |
Facial contact dermatitis due to metronidazole.
Topics: Adult; Antifungal Agents; Dermatitis, Allergic Contact; Drug Eruptions; Facial Dermatoses; Female; H | 1997 |
Loss of deciduous teeth and germs of permanent incisors in a 4-year-old child. An atypic prepubertal periodontitis? A clinical, microbiological, immunological and ultrastructural study.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Anti-Bacterial Agents; Basement Mem | 1997 |
[Tubero-pustular demodicosis].
Topics: Adult; Anti-Infective Agents; Dermatitis, Atopic; Drug Combinations; Facial Dermatoses; Female; Hexa | 1999 |
HIV seronegative eosinophilic pustular folliculitis successfully treated with metronidazole.
Topics: Adult; Eosinophilia; Facial Dermatoses; Female; Folliculitis; Follow-Up Studies; Hand Dermatoses; HI | 2002 |
[Metronidazole (Flagyl) as a therapy variant in "rosacea" and in "perioral dermatitis" (preliminary report)].
Topics: Drug Evaluation; Facial Dermatoses; Humans; Metronidazole; Rosacea | 1979 |
Perioral dermatitis in childhood.
Topics: Administration, Cutaneous; Anti-Inflammatory Agents; Child; Child, Preschool; Drug Therapy, Combinat | 1992 |
Idiopathic recalcitrant facial flushing syndrome.
Topics: Facial Dermatoses; Female; Flushing; Humans; Male; Metronidazole; Middle Aged; Rosacea; Syndrome; Te | 1990 |
[Case report of the facial pyoderma disease picture].
Topics: Acne Vulgaris; Adult; Facial Dermatoses; Female; Humans; Metronidazole; Pyoderma | 1986 |
Cutaneous metastatic Crohn's disease: treatment with metronidazole.
Topics: Crohn Disease; Facial Dermatoses; Granuloma; Humans; Male; Metronidazole; Middle Aged | 1987 |