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metronidazole and Eye Infections, Parasitic

metronidazole has been researched along with Eye Infections, Parasitic in 5 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Eye Infections, Parasitic: Mild to severe infections of the eye and its adjacent structures (adnexa) by adult or larval protozoan or metazoan parasites.

Research Excerpts

ExcerptRelevanceReference
"0) years) with active or past giardiasis diagnosed on the basis of microscopic examination of stool specimens or duodenal secretions--53 were newly diagnosed and untreated (group A), 50 had active infections in spite of metronidazole therapy (group B), and 38 had been successfully treated, with negative stool specimens for 1-3 years (group C)."3.70Ocular changes associated with Giardia lamblia infection in children. ( Ardenti Morini, F; Bulgarini, D; Corsi, A; De Risi, F; Di Iorio, L; Knafelz, D; Nucci, C; Paone, FM; Polito, A, 1998)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
El Nokrashy, A1
Abou Samra, W1
Sobeih, D1
Lamin, A1
Hashish, A1
Tarshouby, S1
Lightman, S1
Sewelam, A1
Navel, V1
Mulliez, A1
Benoist d'Azy, C1
Baker, JS1
Malecaze, J1
Chiambaretta, F1
Dutheil, F1
Hazarika, M1
Pai H, V1
Khanna, V1
Reddy, H1
Tilak, K1
Chawla, K1
Salem, DA1
El-Shazly, A1
Nabih, N1
El-Bayoumy, Y1
Saleh, S1
Corsi, A1
Nucci, C1
Knafelz, D1
Bulgarini, D1
Di Iorio, L1
Polito, A1
De Risi, F1
Ardenti Morini, F1
Paone, FM1

Reviews

1 review available for metronidazole and Eye Infections, Parasitic

ArticleYear
Efficacy of treatments for Demodex blepharitis: A systematic review and meta-analysis.
    The ocular surface, 2019, Volume: 17, Issue:4

    Topics: Animals; Anti-Infective Agents, Local; Antiparasitic Agents; Blepharitis; Eye Infections, Parasitic;

2019

Trials

1 trial available for metronidazole and Eye Infections, Parasitic

ArticleYear
Evaluation of the efficacy of oral ivermectin in comparison with ivermectin-metronidazole combined therapy in the treatment of ocular and skin lesions of Demodex folliculorum.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2013, Volume: 17, Issue:5

    Topics: Acari; Administration, Oral; Adult; Animals; Drug Therapy, Combination; Eye Infections, Parasitic; F

2013

Other Studies

3 other studies available for metronidazole and Eye Infections, Parasitic

ArticleYear
Treatment of presumed trematode-induced granulomatous anterior uveitis among children in rural areas of Egypt.
    Eye (London, England), 2019, Volume: 33, Issue:10

    Topics: Adolescent; Animals; Antiprotozoal Agents; Child; Child, Preschool; Combined Modality Therapy; Corne

2019
Rare Case of Polymicrobial Keratitis With Balantidium coli.
    Cornea, 2016, Volume: 35, Issue:12

    Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Balantidiasis; Balantidium; Coinfection; Contact Lenses

2016
Ocular changes associated with Giardia lamblia infection in children.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:1

    Topics: Adolescent; Animals; Antiprotozoal Agents; Case-Control Studies; Child; Child, Preschool; Eye Infect

1998