metronidazole has been researched along with Exanthema in 14 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Exanthema: Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a 70-year-old female with a medical history of CML, diabetes, hypertension, and hypercholesterolemia who presented to our dermatology clinic for chief complaint of worsening edematous facial rash beginning after initiation of dasatinib." | 8.12 | Facial Edema Associated with Dasatinib: Case Report with Successful Treatment. ( Ambur, A; Nathoo, R; Nyckowski, T; Vinokurov, A, 2022) |
| " We report a case of 16-year-old woman who developed pruritic eruptions after oral metronidazole treatment for diarrhea." | 7.80 | Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) induced by oral metronidazole. ( Bayramgürler, D; Odyakmaz Demirsoy, E; Salman, S; Şikar Aktürk, A; Yıldız, KD, 2014) |
| "We present a 70-year-old female with a medical history of CML, diabetes, hypertension, and hypercholesterolemia who presented to our dermatology clinic for chief complaint of worsening edematous facial rash beginning after initiation of dasatinib." | 4.12 | Facial Edema Associated with Dasatinib: Case Report with Successful Treatment. ( Ambur, A; Nathoo, R; Nyckowski, T; Vinokurov, A, 2022) |
| " We report a case of 16-year-old woman who developed pruritic eruptions after oral metronidazole treatment for diarrhea." | 3.80 | Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) induced by oral metronidazole. ( Bayramgürler, D; Odyakmaz Demirsoy, E; Salman, S; Şikar Aktürk, A; Yıldız, KD, 2014) |
| " She was administered cefoperazone and sulbactam sodium + metronidazole sodium chloride combined with morphine hydrochloride perioperatively, which caused a rash as an adverse side effect." | 1.56 | A case report of rash induced by cefoperazone sodium and sulbactam sodium plus metronidazole sodium chloride combined with morphine hydrochloride. ( Huang, J; Jiang, C; Liu, Z; Zhu, X, 2020) |
| "Severe exanthema (grade III/IV) develops in about 9-19 % of patients with the necessity of cetuximab dose reduction or cessation." | 1.39 | Cetuximab-induced skin exanthema: prophylactic and reactive skin therapy are equally effective. ( Berger, MR; Galle, PR; Gockel, I; Graf, C; Herzog, J; Lang, H; Möhler, M; Schimanski, CC; Theobald, M; Wehler, TC, 2013) |
| "Acute generalized exanthemic pustulosis often presents dramatically with the abrupt onset of a widespread pustular eruption on an erythematous base, with a frequently positive Nikolsky sign." | 1.29 | Acute generalized exanthemic pustulosis. ( Heymann, WR; Manders, SM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 5 (35.71) | 2.80 |
| Authors | Studies |
|---|---|
| Nyckowski, T | 1 |
| Ambur, A | 1 |
| Vinokurov, A | 1 |
| Nathoo, R | 1 |
| Lee, H | 1 |
| Kim, KH | 1 |
| Huang, J | 1 |
| Zhu, X | 1 |
| Jiang, C | 1 |
| Liu, Z | 1 |
| Baghad, B | 1 |
| El Fatoiki, FZ | 1 |
| Benhsaien, I | 1 |
| Bousfiha, AA | 1 |
| Puel, A | 1 |
| Migaud, M | 1 |
| Chiheb, S | 1 |
| Ailal, F | 1 |
| Zhang, H | 1 |
| Xie, Z | 1 |
| Nespoulous, L | 1 |
| Matei, I | 1 |
| Charissoux, A | 1 |
| Bédane, C | 1 |
| Assikar, S | 1 |
| Chaabane, A | 1 |
| Romdhane, HB | 1 |
| Brahim, HB | 1 |
| Fredj, NB | 1 |
| Chadli, Z | 1 |
| Boughattas, NA | 1 |
| Chakroun, M | 1 |
| Aouam, K | 1 |
| Parke, L | 1 |
| Diernaes, J | 1 |
| Bygum, A | 1 |
| Wehler, TC | 1 |
| Graf, C | 1 |
| Möhler, M | 1 |
| Herzog, J | 1 |
| Berger, MR | 1 |
| Gockel, I | 1 |
| Lang, H | 1 |
| Theobald, M | 1 |
| Galle, PR | 1 |
| Schimanski, CC | 1 |
| Şikar Aktürk, A | 1 |
| Bayramgürler, D | 1 |
| Salman, S | 1 |
| Yıldız, KD | 1 |
| Odyakmaz Demirsoy, E | 1 |
| Savely, G | 1 |
| Manders, SM | 1 |
| Heymann, WR | 1 |
| Watsky, KL | 1 |
| Luger, A | 1 |
1 review available for metronidazole and Exanthema
| Article | Year |
|---|---|
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) associated with pristinamycin, secnidazole, and nefopam, with a review of the literature.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Antiprotozoal Agents; Drug Eruptions; | 2018 |
13 other studies available for metronidazole and Exanthema
| Article | Year |
|---|---|
Facial Edema Associated with Dasatinib: Case Report with Successful Treatment.
Topics: Aged; Antineoplastic Agents; Dasatinib; Edema; Exanthema; Face; Female; Gels; Humans; Leukemia, Myel | 2022 |
Treatment of pediatric periorificial dermatitis with topical calcineurin inhibitor and topical/oral metronidazole.
Topics: Administration, Topical; Anti-Bacterial Agents; Calcineurin Inhibitors; Child; Dermatitis, Perioral; | 2021 |
A case report of rash induced by cefoperazone sodium and sulbactam sodium plus metronidazole sodium chloride combined with morphine hydrochloride.
Topics: Adult; Anti-Bacterial Agents; Cefoperazone; Cesarean Section; Chlorides; Drug Therapy, Combination; | 2020 |
Pediatric Demodicosis Associated with Gain-of-Function Variant in STAT1 Presenting as Rosacea-Type Rash.
Topics: Alleles; Child; DNA Mutational Analysis; Exanthema; Female; Gain of Function Mutation; Genetic Assoc | 2021 |
Symmetrical drug-related intertriginous and flexural exanthema induced by metronidazole suppository.
Topics: Antifungal Agents; Drug Eruptions; Exanthema; Female; Humans; Metronidazole; Middle Aged; Suppositor | 2021 |
Meglumine antimoniate-induced DRESS: original case with a positive skin test.
Topics: Animals; Antiprotozoal Agents; Cryotherapy; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; | 2018 |
Papulopustular Facial Eruption in a Child: A Quiz.
Topics: Administration, Oral; Administration, Topical; Child, Preschool; Dermatitis, Perioral; Diagnosis, Di | 2019 |
Cetuximab-induced skin exanthema: prophylactic and reactive skin therapy are equally effective.
Topics: Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antibo | 2013 |
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) induced by oral metronidazole.
Topics: Adolescent; Antitrichomonal Agents; Buttocks; Diarrhea; Drug Eruptions; Exanthema; Female; Humans; M | 2014 |
Neuralgia and demyelinating plaques: MS or lyme disease?
Topics: Anti-Bacterial Agents; Antigens, Bacterial; Blotting, Western; Borrelia burgdorferi; Ceftriaxone; Di | 2005 |
Acute generalized exanthemic pustulosis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Ampicillin; Cefazolin; Dermatitis, Exfoliative; Diagn | 1994 |
Acute generalized exanthematous pustulosis induced by metronidazole: the role of patch testing.
Topics: Adult; Anti-Infective Agents; Drug Eruptions; Edema; Erythema; Exanthema; Humans; Male; Metronidazol | 1999 |
[Syphilis diagnosis in the age of antibiotics].
Topics: Adult; Aged; Alopecia; Anti-Bacterial Agents; Balanitis; Biopsy; Child; Child, Preschool; Chloramphe | 1971 |