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metronidazole and Esophageal Diseases

metronidazole has been researched along with Esophageal Diseases in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Esophageal Diseases: Pathological processes in the ESOPHAGUS.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Samour, JH1
Bailey, TA1
Cooper, JE1
Dechant, JE1
MacDonald, DG1
Crawford, WH1
O'Connor, BP1
Salim, AS1

Other Studies

3 other studies available for metronidazole and Esophageal Diseases

ArticleYear
Trichomoniasis in birds of prey (order Falconiformes) in Bahrain.
    The Veterinary record, 1995, Apr-08, Volume: 136, Issue:14

    Topics: Air Sacs; Animals; Bahrain; Bird Diseases; Birds; Crop, Avian; Dimetridazole; Electrolytes; Esophage

1995
Pleuritis associated with perforation of an isolated oesophageal ulcer in a horse.
    Equine veterinary journal, 1998, Volume: 30, Issue:2

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Clinical Chemistry Tests; C

1998
Jejunostomy feeding for the conservative management of spontaneous rupture of the oesophagus.
    The British journal of clinical practice, 1991,Spring, Volume: 45, Issue:1

    Topics: Adult; Cefotaxime; Drug Therapy, Combination; Enteral Nutrition; Esophageal Diseases; Humans; Jejuno

1991