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metronidazole and Erythema Nodosum

metronidazole has been researched along with Erythema Nodosum in 4 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Erythema Nodosum: An erythematous eruption commonly associated with drug reactions or infection and characterized by inflammatory nodules that are usually tender, multiple, and bilateral. These nodules are located predominantly on the shins with less common occurrence on the thighs and forearms. They undergo characteristic color changes ending in temporary bruise-like areas. This condition usually subsides in 3-6 weeks without scarring or atrophy.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, HC1
Kim, HW1
Park, CG1
Ko, JY1
Geary, RJ1
Long, LL1
Mutasim, DF1
Taylor, JA1
Walther, H1

Trials

1 trial available for metronidazole and Erythema Nodosum

ArticleYear
Pharmacodynamic observations on metronidazole therapy. Side effects in endocrine, metabolic and auto-immune disorders. 3. Anti-ischemic and anti-inflammatory action in peripheral vascular disorders.
    Proceedings of the Western Pharmacology Society, 1966, Volume: 9

    Topics: Blood Circulation; Blood Flow Velocity; Blood Pressure; Clinical Trials as Topic; Diabetes Complicat

1966

Other Studies

3 other studies available for metronidazole and Erythema Nodosum

ArticleYear
Metastatic Crohn disease clinically reminiscent of erythema nodosum on the right leg.
    Cutis, 2016, Volume: 98, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Colonoscopy; Crohn Disease; Erythema Nodosum; Female; Glucocorticoi

2016
Bowel bypass syndrome without bowel bypass.
    Cutis, 1999, Volume: 63, Issue:1

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Biopsy; Ciprofloxacin; Erythema Nodosum; Fem

1999
[Urogenital trichomoniasis in dermatologic practice].
    Dermatologische Monatschrift, 1969, Volume: 155, Issue:12

    Topics: Adult; Erythema Nodosum; Female; Humans; Metronidazole; Middle Aged; Trichomonas Vaginitis

1969