metronidazole has been researched along with Epiglottitis in 1 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Epiglottitis: Inflammation of the EPIGLOTTIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute epiglottitis is a disease that may become serious or even fatal because of sudden upper airway obstruction." | 1.35 | Efficacy of spinal needle aspiration for epiglottic abscess in 90 patients with acute epiglottitis. ( Hong, JW; Kim, MG; Kim, SG; Kim, TH; Lee, JH; Park, DJ; Shim, JS; Yeo, SG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SG | 1 |
| Lee, JH | 1 |
| Park, DJ | 1 |
| Hong, JW | 1 |
| Kim, TH | 1 |
| Kim, MG | 1 |
| Shim, JS | 1 |
| Yeo, SG | 1 |
1 other study available for metronidazole and Epiglottitis
| Article | Year |
|---|---|
Efficacy of spinal needle aspiration for epiglottic abscess in 90 patients with acute epiglottitis.
Topics: Acute Disease; Adult; Airway Obstruction; Anti-Bacterial Agents; Cephalosporins; Combined Modality T | 2009 |