metronidazole has been researched along with Eperythrozoonosis in 21 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-three women with bacterial vaginosis (clue cells of at least 20% plus vaginal pH of at least 4." | 2.67 | Efficacy of intravaginal 0.75% metronidazole gel for the treatment of bacterial vaginosis. ( Briselden, AM; Eschenbach, DA; Hillier, SL; Lipinski, C, 1993) |
| "Other causes of vaginitis are also discussed." | 2.37 | Vaginitis: current microbiologic and clinical concepts. ( Embil, JA; Hill, LV, 1986) |
| "As metronidazole effectively treats full BV, but is ineffective against other forms of AVF, the present data may help to explain why its use to prevent PTB has not been successful in most studies." | 1.35 | Predictive value for preterm birth of abnormal vaginal flora, bacterial vaginosis and aerobic vaginitis during the first trimester of pregnancy. ( Bellen, G; Donders, GG; Reybrouck, R; Riphagen, I; Van Calsteren, K; Van den Bosch, T; Van Lierde, S, 2009) |
| "An association between M." | 1.28 | Mycoplasma hominis in women with bacterial vaginosis. ( Deodhar, LP; Pandit, DV, 1992) |
| "One female developed septicemia after cancer surgery, one male after heart surgery." | 1.27 | Septicemia due to Mycoplasma hominis. ( Bøe, O; Iversen, OE; Mehl, A, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (38.10) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Wood, GE | 1 |
| Kim, CM | 1 |
| Aguila, LKT | 1 |
| Cichewicz, RH | 1 |
| Balkus, JE | 2 |
| Manhart, LE | 2 |
| Jensen, JS | 1 |
| Anzala, O | 2 |
| Kimani, J | 2 |
| Schwebke, J | 2 |
| Shafi, J | 2 |
| Rivers, C | 2 |
| Kabare, E | 2 |
| McClelland, RS | 1 |
| Fürnkranz, U | 1 |
| Walochnik, J | 1 |
| Henrich, B | 1 |
| Thi Trung Thu, T | 1 |
| Margarita, V | 1 |
| Cocco, AR | 1 |
| Marongiu, A | 1 |
| Dessì, D | 1 |
| Rappelli, P | 1 |
| Fiori, PL | 1 |
| Horner, P | 1 |
| Blee, K | 1 |
| O'Mahony, C | 1 |
| Muir, P | 1 |
| Evans, C | 1 |
| Radcliffe, K | 1 |
| Lee, J | 1 |
| Scott McClelland, R | 1 |
| Donders, GG | 1 |
| Van Calsteren, K | 1 |
| Bellen, G | 1 |
| Reybrouck, R | 1 |
| Van den Bosch, T | 1 |
| Riphagen, I | 1 |
| Van Lierde, S | 1 |
| Wang, PJ | 1 |
| Xie, CB | 1 |
| Bøe, O | 1 |
| Iversen, OE | 1 |
| Mehl, A | 1 |
| Hillier, SL | 1 |
| Lipinski, C | 1 |
| Briselden, AM | 1 |
| Eschenbach, DA | 1 |
| Hay, PE | 1 |
| Pavelić, Z | 1 |
| Skalko-Basnet, N | 1 |
| Jalsenjak, I | 1 |
| Csütörtöki, V | 1 |
| Stipkovits, L | 1 |
| Hofstetter, A | 1 |
| Schmiedt, E | 1 |
| Weissenbacher, ER | 1 |
| Frank, S | 1 |
| Roser, H | 1 |
| Deodhar, LP | 1 |
| Pandit, DV | 1 |
| Rousseau, S | 1 |
| Morisset, ME | 1 |
| Knoefel, F | 1 |
| Gattereau, D | 1 |
| Morisset, R | 1 |
| Hill, LV | 1 |
| Embil, JA | 1 |
| Smith, GR | 1 |
| Turner, A | 1 |
| Murray, LG | 1 |
| Oliphant, JC | 1 |
| Banner, EA | 1 |
| Penza, J | 1 |
| Rankin, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Preventing Preterm Birth With Probiotics - Pilot Randomised Trial[NCT02692820] | 304 participants (Actual) | Interventional | 2016-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for metronidazole and Eperythrozoonosis
| Article | Year |
|---|---|
Vaginitis: current microbiologic and clinical concepts.
Topics: Antibody Formation; Antifungal Agents; Candidiasis; Candidiasis, Vulvovaginal; Carrier State; Female | 1986 |
Infectious vaginopathies in pregnancy.
Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Glucocorticoids; Gonorrhea; Haemophilus Infect | 1970 |
3 trials available for metronidazole and Eperythrozoonosis
| Article | Year |
|---|---|
Mycoplasma genitalium Infection in Kenyan and US Women.
Topics: Administration, Intravaginal; Adolescent; Adult; Anti-Bacterial Agents; Drug Resistance, Bacterial; | 2018 |
Periodic Presumptive Treatment for Vaginal Infections May Reduce the Incidence of Sexually Transmitted Bacterial Infections.
Topics: Adult; Anti-Infective Agents; Chlamydia Infections; Chlamydia trachomatis; Drug Therapy, Combination | 2016 |
Efficacy of intravaginal 0.75% metronidazole gel for the treatment of bacterial vaginosis.
Topics: Administration, Intravaginal; Adult; Bacteroides Infections; Double-Blind Method; Female; Gardnerell | 1993 |
16 other studies available for metronidazole and Eperythrozoonosis
| Article | Year |
|---|---|
Topics: Anti-Bacterial Agents; Doxycycline; Drug Resistance, Bacterial; Female; Humans; Male; Metronidazole; | 2023 |
Mycoplasma hominis shows strain-dependent increase in resistance to selected antibiotics after symbiosis with Trichomonas vaginalis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Female; Humans; Metronidazole; Mic | 2018 |
Topics: Amniotic Fluid; Anti-Bacterial Agents; Extraembryonic Membranes; Female; Humans; Metronidazole; Myco | 2018 |
2015 UK National Guideline on the management of non-gonococcal urethritis.
Topics: Anti-Bacterial Agents; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Disease Management | 2016 |
Predictive value for preterm birth of abnormal vaginal flora, bacterial vaginosis and aerobic vaginitis during the first trimester of pregnancy.
Topics: Adult; Anti-Infective Agents; Female; Humans; Metronidazole; Mycoplasma hominis; Mycoplasma Infectio | 2009 |
[Mycoplasma hominis symbiosis and Trichomonas vaginalis metronidazole resistance].
Topics: Coinfection; Female; Humans; Metronidazole; Mycoplasma hominis; Mycoplasma Infections; Trichomonas I | 2012 |
Septicemia due to Mycoplasma hominis.
Topics: Amoxicillin; Ampicillin; Clindamycin; Doxycycline; Female; Humans; Male; Metronidazole; Mycoplasma I | 1983 |
Therapy of bacterial vaginosis.
Topics: Antitrichomonal Agents; Bacteroides; Bacteroides Infections; Clindamycin; Drug Therapy, Combination; | 1998 |
Liposomes containing drugs for treatment of vaginal infections.
Topics: Administration, Intravaginal; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective | 1999 |
[Detection of Mycoplasma pneumoniae infections in female sex organs].
Topics: Adult; Female; Genitalia, Female; Humans; Metronidazole; Mycoplasma; Mycoplasma Infections; Uterine | 1977 |
[Urethritis syndrome and atypical germ flora of the exterior female genitalia (author's transl)].
Topics: Candidiasis, Vulvovaginal; Cervix Uteri; Chronic Disease; Female; Humans; Male; Metronidazole; Mycop | 1976 |
[Treatment of unspecific urethritis].
Topics: Antigens, Viral; Antiviral Agents; Female; Herpes Simplex; Humans; Male; Metronidazole; Mycoplasma I | 1975 |
Mycoplasma hominis in women with bacterial vaginosis.
Topics: Adult; Bacteria, Anaerobic; Doxycycline; Female; Gardnerella vaginalis; Humans; India; Metronidazole | 1992 |
The role of laparoscopy in acute pelvic infections.
Topics: Acute Disease; Adult; Ampicillin; Chlamydia Infections; Drug Therapy, Combination; Female; Gonorrhea | 1991 |
The weak immunogenicity of Fusobacterium necrophorum.
Topics: Animals; Bacterial Vaccines; Freund's Adjuvant; Fusobacterium Infections; Fusobacterium necrophorum; | 1985 |
Vaginitis.
Topics: Adolescent; Candida albicans; Candidiasis, Vulvovaginal; Child; Corynebacterium Infections; Female; | 1974 |