Page last updated: 2024-10-31

metronidazole and Eosinophilia, Tropical

metronidazole has been researched along with Eosinophilia, Tropical in 15 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"Metronidazole was withdrawn and vancomycin was changed by teicoplanin 10 and 15 days later, respectively."5.91Cefotaxime-induced drug reaction with eosinophilia and systemic symptom in a child with cross-reactivity to other cephalosporins and cosensitization to teicoplanin. ( Aouam, K; Ben Fadhel, N; Ben Fredj, N; Ben Romdhane, H; Chaabane, A; Chadli, Z; Mansour, K, 2023)
"Treatment with metronidazole resulted in complete clearance of the lesion."5.31HIV seronegative eosinophilic pustular folliculitis successfully treated with metronidazole. ( Hayakawa, J; Inaoka, M; Shiohara, T, 2002)
"Metronidazole was withdrawn and vancomycin was changed by teicoplanin 10 and 15 days later, respectively."1.91Cefotaxime-induced drug reaction with eosinophilia and systemic symptom in a child with cross-reactivity to other cephalosporins and cosensitization to teicoplanin. ( Aouam, K; Ben Fadhel, N; Ben Fredj, N; Ben Romdhane, H; Chaabane, A; Chadli, Z; Mansour, K, 2023)
"Eosinophilic gastroenteritis is a rare inflammatory disorder of the gastrointestinal tract."1.62Eosinophilic gastroenteritis in an adolescent male with history of chronic bullous disease. ( Castor, MAR; Murillo, JML; Recto, MST; Tan-Lim, CSC, 2021)
"Treatment with praziquantel followed by metronidazole and tinidazole reduced abnormalities in the liver and eosinophilia."1.36A case of probable mixed-infection with Clonorchis sinensis and Fasciola sp.: CT and parasitological findings. ( Choi, WH; Chu, JP; Kim, JJ; Kim, TY; Lee, YS; Oh, IH; Song, HO; Yun, JH, 2010)
"Treatment with metronidazole resulted in complete clearance of the lesion."1.31HIV seronegative eosinophilic pustular folliculitis successfully treated with metronidazole. ( Hayakawa, J; Inaoka, M; Shiohara, T, 2002)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's1 (6.67)18.2507
2000's1 (6.67)29.6817
2010's3 (20.00)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Dilley, M1
Geng, B1
Mansour, K1
Ben Fadhel, N1
Ben Fredj, N1
Ben Romdhane, H1
Chaabane, A2
Chadli, Z2
Aouam, K2
Tan-Lim, CSC1
Murillo, JML1
Recto, MST1
Castor, MAR1
Romdhane, HB1
Brahim, HB1
Fredj, NB1
Boughattas, NA1
Chakroun, M1
Cortizo-Vidal, S1
Rodríguez-Otero, LM1
Villamil-Cajoto, I1
Llovo-Taboada, J1
Kim, TY1
Lee, YS1
Yun, JH1
Kim, JJ1
Choi, WH1
Oh, IH1
Song, HO1
Chu, JP1
Simpson-Dent, S1
Fearfield, LA1
Staughton, RC1
Inaoka, M1
Hayakawa, J1
Shiohara, T1
Vaidya, AB1
Doshi, JC1
Gupta, KC1
Paul, T1
Sheth, UK1
Kristenson, M1
Frydén, A1
Karageosov, I1
Mischev, D1
Rao, NR1
Reddy, VV1
Antani, JA1
Srinivas, HV1
Schreiber, W1
Holmes, GK1
Gelfand, M1
Boyt, W1
Mackenzie, P1

Reviews

1 review available for metronidazole and Eosinophilia, Tropical

ArticleYear
Immediate and Delayed Hypersensitivity Reactions to Antibiotics: Aminoglycosides, Clindamycin, Linezolid, and Metronidazole.
    Clinical reviews in allergy & immunology, 2022, Volume: 62, Issue:3

    Topics: Aminoglycosides; Anaphylaxis; Angioedema; Anti-Bacterial Agents; Clindamycin; Dermatitis, Allergic C

2022

Trials

1 trial available for metronidazole and Eosinophilia, Tropical

ArticleYear
Treatment of tropical pulmonary eosinophilia with metronidazole.
    The Journal of tropical medicine and hygiene, 1973, Volume: 76, Issue:6

    Topics: Blood Sedimentation; Clinical Trials as Topic; Eosinophilia; Humans; India; Leukocyte Count; Lung Di

1973

Other Studies

13 other studies available for metronidazole and Eosinophilia, Tropical

ArticleYear
Cefotaxime-induced drug reaction with eosinophilia and systemic symptom in a child with cross-reactivity to other cephalosporins and cosensitization to teicoplanin.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:2

    Topics: Adult; Cefotaxime; Cephalosporins; Child; Child, Preschool; Drug Hypersensitivity Syndrome; Eosinoph

2023
Eosinophilic gastroenteritis in an adolescent male with history of chronic bullous disease.
    BMJ case reports, 2021, Feb-04, Volume: 14, Issue:2

    Topics: Abdominal Pain; Adolescent; Anti-Infective Agents; Appendicitis; Diarrhea; Enteritis; Eosinophilia;

2021
Meglumine antimoniate-induced DRESS: original case with a positive skin test.
    Acta parasitologica, 2018, Dec-19, Volume: 63, Issue:4

    Topics: Animals; Antiprotozoal Agents; Cryotherapy; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema;

2018
[Eosinophilia in an adopted native Ethiopian girl].
    Enfermedades infecciosas y microbiologia clinica, 2010, Volume: 28, Issue:1

    Topics: Adoption; Amebiasis; Animals; Anthelmintics; Antiprotozoal Agents; Blastocystis hominis; Blastocysti

2010
A case of probable mixed-infection with Clonorchis sinensis and Fasciola sp.: CT and parasitological findings.
    The Korean journal of parasitology, 2010, Volume: 48, Issue:2

    Topics: Adult; Animals; Anthelmintics; Antibodies, Protozoan; Clonorchiasis; Clonorchis sinensis; Entamoeba

2010
HIV associated eosinophilic folliculitis--differential diagnosis and management.
    Sexually transmitted infections, 1999, Volume: 75, Issue:5

    Topics: Administration, Topical; Anti-Infective Agents; Anti-Inflammatory Agents; Antifungal Agents; Eosinop

1999
HIV seronegative eosinophilic pustular folliculitis successfully treated with metronidazole.
    Journal of the American Academy of Dermatology, 2002, Volume: 46, Issue:5 Suppl

    Topics: Adult; Eosinophilia; Facial Dermatoses; Female; Folliculitis; Follow-Up Studies; Hand Dermatoses; HI

2002
Metronidazole in tropical eosinophillia: a phase II trial.
    Indian journal of medical sciences, 1976, Volume: 30, Issue:10

    Topics: Adolescent; Adult; Eosinophilia; Female; Filariasis; Humans; Lung Diseases, Parasitic; Male; Metroni

1976
Pneumonitis caused by metronidazole.
    JAMA, 1988, Jul-08, Volume: 260, Issue:2

    Topics: Adult; Eosinophilia; Female; Humans; Metronidazole; Pulmonary Fibrosis

1988
[Colpitis emphysematosa trichomonalis].
    Zentralblatt fur Gynakologie, 1974, Jan-18, Volume: 96, Issue:3

    Topics: Adult; Blister; Colposcopy; Eosinophilia; Estriol; Female; Hemostatics; Humans; Hypersensitivity; Me

1974
Clinical evaluation of metronidazole in tropical pulmonary eosinophilia: a preliminary report.
    The Indian journal of chest diseases, 1973, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Eosinophilia; Humans; Lung Diseases; Metronidazole; Middle Aged

1973
[Parasitoses of the intestinal tract].
    Fortschritte der Medizin, 1974, Mar-14, Volume: 92, Issue:8

    Topics: Bephenium Compounds; Diagnosis, Differential; Eosinophilia; Giardiasis; Humans; Intestinal Diseases,

1974
A study to investigate the pathogenicity of a parasite resembling Acanthocheilonema perstans.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1969, Volume: 63, Issue:4

    Topics: Diethylcarbamazine; Dipetalonema; Eosinophilia; Humans; Joint Diseases; Metronidazole; Nematode Infe

1969