metronidazole has been researched along with Enterocolitis in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Enterocolitis: Inflammation of the MUCOSA of both the SMALL INTESTINE and the LARGE INTESTINE. Etiology includes ISCHEMIA, infections, allergic, and immune responses.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although all antibiotic treatments caused similar increases in pathogen colonization, the development of enterocolitis was seen only when streptomycin or vancomycin was used; no significant pathology was observed with the use of metronidazole." | 3.77 | The intestinal microbiota plays a role in Salmonella-induced colitis independent of pathogen colonization. ( Antunes, LC; Croxen, MA; Ferreira, RB; Finlay, BB; Gill, N; Russell, SL; Willing, BP, 2011) |
| "Lactose intolerance is a secondary problem most commonly associated with rotavirus infection, but it can be caused by any condition affecting the small intestine." | 1.30 | Association of Clostridium difficile with enterocolitis and lactose intolerance in a foal. ( Parsons, DA; Staempfli, HR; Weese, JS, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferreira, RB | 1 |
| Gill, N | 1 |
| Willing, BP | 1 |
| Antunes, LC | 1 |
| Russell, SL | 1 |
| Croxen, MA | 1 |
| Finlay, BB | 1 |
| Weese, JS | 2 |
| Cote, NM | 1 |
| deGannes, RV | 1 |
| Lentelink, MB | 1 |
| de Vries, TW | 1 |
| van Dijk, KN | 1 |
| Parsons, DA | 1 |
| Staempfli, HR | 1 |
| Nelson, SP | 1 |
| Lin, PL | 1 |
| Miller, J | 1 |
| Katz, BZ | 1 |
| Gonzalez-Crussi, F | 1 |
| Kessler, BH | 1 |
| So, HB | 1 |
| Becker, JM | 1 |
| Thadepalli, H | 1 |
1 review available for metronidazole and Enterocolitis
| Article | Year |
|---|---|
Animal models for anaerobic infections.
Topics: Animals; Bacteria, Anaerobic; Bacterial Infections; Bacteroides Infections; Disease Models, Animal; | 1985 |
6 other studies available for metronidazole and Enterocolitis
| Article | Year |
|---|---|
The intestinal microbiota plays a role in Salmonella-induced colitis independent of pathogen colonization.
Topics: Animals; Anti-Infective Agents; Bacteria; Cation Transport Proteins; Ecosystem; Enterocolitis; Feces | 2011 |
Evaluation of in vitro properties of di-tri-octahedral smectite on clostridial toxins and growth.
Topics: Animals; Anti-Infective Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Clos | 2003 |
Accidental metronidazole overdose in a preterm newborn.
Topics: Antitrichomonal Agents; Drug Overdose; Enterocolitis; Female; Humans; Infant, Newborn; Infant, Prema | 1997 |
Association of Clostridium difficile with enterocolitis and lactose intolerance in a foal.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; beta-Galactosidase; Clostridioides difficile; Clos | 1999 |
Cryptosporidia enterocolitis in an immunocompetent infant treated with paromomycin.
Topics: Animals; Anti-Infective Agents; Biopsy; Cryptosporidiosis; Duodenum; Enterocolitis; Humans; Immunoco | 1999 |
Crohn's disease mimicking enterocolitis in a patient with an endorectal pull-through for Hirschsprung's disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Colonoscopy; Crohn Disease; Diagnosis, Differential; | 1999 |