metronidazole has been researched along with Enterocolitis, Pseudomembranous in 400 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Enterocolitis, Pseudomembranous: An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To date, no randomized trial to address the use of adjunctive rifampin in addition to metronidazole for the treatment of Clostridium difficile-associated diarrhea has been reported." | 9.12 | Prospective, randomized inpatient study of oral metronidazole versus oral metronidazole and rifampin for treatment of primary episode of Clostridium difficile-associated diarrhea. ( Holmes, S; Lagrotteria, D; Lee, C; Smaill, F; Smieja, M, 2006) |
| "Samples from patients with Clostridium difficile-associated diarrhea (CDAD) that were randomized to fusidic acid (n = 59) or metronidazole (n = 55) therapy for 7 days were cultured for Clostridium difficile in feces on days 1, 8 to 13, and 35 to 40." | 9.12 | Frequent emergence of resistance in Clostridium difficile during treatment of C. difficile-associated diarrhea with fusidic acid. ( Akerlund, T; Bäck, E; Burman, LG; Norén, T; Odenholt, I; Wullt, M, 2006) |
| "In the absence of clear guidelines, empiric metronidazole should be reserved for strongly presumptive CDAD patients (older patients with comorbid conditions receiving broad-spectrum antibiotics associated with CDAD) who cannot hemodynamically or otherwise tolerate diarrhea." | 9.10 | Effectiveness and appropriateness of empiric metronidazole for Clostridium difficile-associated diarrhea. ( Glatt, AE; Vasa, CV, 2003) |
| "We conducted a prospective, randomized study to compare the efficacy of oral fusidic acid, oral metronidazole, oral vancomycin, and oral teicoplanin for the treatment of Clostridium difficile-associated diarrhea." | 9.08 | Comparison of vancomycin, teicoplanin, metronidazole, and fusidic acid for the treatment of Clostridium difficile-associated diarrhea. ( Graninger, W; Hasenhündl, M; Hirschl, AM; Parschalk, B; Wenisch, C, 1996) |
| " difficile infection after therapy with metronidazole, vancomycin, or combination therapy exclusively in patients with hematologic malignancies, including those undergoing hematopoietic stem cell transplant for a hematologic condition." | 7.80 | A retrospective review of metronidazole and vancomycin in the management of Clostridium difficile infection in patients with hematologic malignancies. ( Bhatt, V; Parmar, SR; Schuster, M; Yang, J; Zhang, Q, 2014) |
| "The feasibility of fidaxomicin versus vancomycin and metronidazole (conventional therapy) was assessed in 59 transplant recipients with 61 episodes of Clostridium difficile-associated diarrhea (CDAD)." | 7.79 | Fidaxomicin versus conventional antimicrobial therapy in 59 recipients of solid organ and hematopoietic stem cell transplantation with Clostridium difficile-associated diarrhea. ( Clutter, DS; Dubrovskaya, Y; Merl, MY; Press, R; Safdar, A; Teperman, L, 2013) |
| "We report the first case of anaphylaxis to oral vancomycin in a cystic fibrosis patient with severe and relapsing Clostridium difficile infection (CDI) refractory to metronidazole." | 7.79 | Severe anaphylaxis caused by orally administered vancomycin to a patient with Clostridium difficile infection. ( Bossé, D; Cantin, AM; Lemire, C; Ménard, F; Ruel, J; Valiquette, L, 2013) |
| " difficile colitis who received intravenous metronidazole as initial monotherapy." | 7.71 | Intravenous metronidazole for the treatment of Clostridium difficile colitis. ( Fernandez, A; Friedenberg, F; Kaul, V; Levine, GM; Niami, P, 2001) |
| " Vancomycin dosage ranged from 125 to 500 mg four times daily for an average of about ten days." | 5.27 | Treatment of antibiotic-associated colitis with vancomycin. ( Buggy, B; Deery, HG; Fekety, R; Silva, J, 1984) |
| "To date, no randomized trial to address the use of adjunctive rifampin in addition to metronidazole for the treatment of Clostridium difficile-associated diarrhea has been reported." | 5.12 | Prospective, randomized inpatient study of oral metronidazole versus oral metronidazole and rifampin for treatment of primary episode of Clostridium difficile-associated diarrhea. ( Holmes, S; Lagrotteria, D; Lee, C; Smaill, F; Smieja, M, 2006) |
| "Samples from patients with Clostridium difficile-associated diarrhea (CDAD) that were randomized to fusidic acid (n = 59) or metronidazole (n = 55) therapy for 7 days were cultured for Clostridium difficile in feces on days 1, 8 to 13, and 35 to 40." | 5.12 | Frequent emergence of resistance in Clostridium difficile during treatment of C. difficile-associated diarrhea with fusidic acid. ( Akerlund, T; Bäck, E; Burman, LG; Norén, T; Odenholt, I; Wullt, M, 2006) |
| "Our objective was to document how intake of Lactobacillus plantarum 299v affects the concentrations of fecal organic acids during and after metronidazole treatment in 19 patients with recurrent Clostridium difficile-associated diarrhea." | 5.12 | Lactobacillus plantarum 299v enhances the concentrations of fecal short-chain fatty acids in patients with recurrent clostridium difficile-associated diarrhea. ( Berggren, A; Johansson Hagslätt, ML; Odenholt, I; Wullt, M, 2007) |
| "In the absence of clear guidelines, empiric metronidazole should be reserved for strongly presumptive CDAD patients (older patients with comorbid conditions receiving broad-spectrum antibiotics associated with CDAD) who cannot hemodynamically or otherwise tolerate diarrhea." | 5.10 | Effectiveness and appropriateness of empiric metronidazole for Clostridium difficile-associated diarrhea. ( Glatt, AE; Vasa, CV, 2003) |
| "We conducted a prospective, randomized study to compare the efficacy of oral fusidic acid, oral metronidazole, oral vancomycin, and oral teicoplanin for the treatment of Clostridium difficile-associated diarrhea." | 5.08 | Comparison of vancomycin, teicoplanin, metronidazole, and fusidic acid for the treatment of Clostridium difficile-associated diarrhea. ( Graninger, W; Hasenhündl, M; Hirschl, AM; Parschalk, B; Wenisch, C, 1996) |
| " Oral metronidazole is used to treat antibiotic-associated colitis (pseudomembranous colitis)." | 5.08 | Metronidazole may inhibit intestinal colonization with Clostridium difficile. ( Cleary, RK; Fernandez, FB; Fowler, JJ; Grossmann, R; Lampman, RM; Stull, TS; Walters, MR, 1998) |
| " Key search terms included Clostridium difficile, Clostridium infections, pseudomembranous colitis, antibiotic-associated diarrhea, Clostridium difficile-associated diarrhea, elderly, geriatric, epidemiology, microbiology, diagnosis, risk factors, treatment, drug therapy, vancomycin, metronidazole, and fidaxomicin." | 4.88 | Clostridium difficile infection in older adults: a review and update on its management. ( Kee, VR, 2012) |
| " difficile diarrhea with metronidazole or vancomycin is highly effective at relieving symptoms." | 4.80 | Treatment of Clostridium difficile-associated diarrhea and colitis. ( Gerding, DN, 2000) |
| " Since the aetiology of antibiotic-associated colitis was discovered 14 years ago, two antibiotics in particular, metronidazole and vancomycin, have been used to treat C." | 4.78 | Clostridium difficile infection: responses, relapses and re-infections. ( Spencer, RC; Wilcox, MH, 1992) |
| " She presented with nine recurrent episodes of Clostridium difficile infection including fever, foul smelling diarrhea, and respiratory distress with failed sustained responses to compliant treatment using metronidazole and pulsed vancomycin therapy." | 3.88 | Clostridium difficile cure with fecal microbiota transplantation in a child with Pompe disease: a case report. ( Dow, DE; Seed, PC, 2018) |
| "The promotion of colonization with vancomycin-resistant enterococci (VRE) is one potential side effect during treatment of Clostridium difficile-associated diarrhea (CDAD), resulting from disturbances in gut microbiota." | 3.83 | Cadazolid Does Not Promote Intestinal Colonization of Vancomycin-Resistant Enterococci in Mice. ( Clozel, M; Enderlin-Paput, M; Locher, HH; Pfaff, P; Ritz, D; Seiler, P; Weiss, M, 2016) |
| " difficile infection after therapy with metronidazole, vancomycin, or combination therapy exclusively in patients with hematologic malignancies, including those undergoing hematopoietic stem cell transplant for a hematologic condition." | 3.80 | A retrospective review of metronidazole and vancomycin in the management of Clostridium difficile infection in patients with hematologic malignancies. ( Bhatt, V; Parmar, SR; Schuster, M; Yang, J; Zhang, Q, 2014) |
| "The feasibility of fidaxomicin versus vancomycin and metronidazole (conventional therapy) was assessed in 59 transplant recipients with 61 episodes of Clostridium difficile-associated diarrhea (CDAD)." | 3.79 | Fidaxomicin versus conventional antimicrobial therapy in 59 recipients of solid organ and hematopoietic stem cell transplantation with Clostridium difficile-associated diarrhea. ( Clutter, DS; Dubrovskaya, Y; Merl, MY; Press, R; Safdar, A; Teperman, L, 2013) |
| "We report the first case of anaphylaxis to oral vancomycin in a cystic fibrosis patient with severe and relapsing Clostridium difficile infection (CDI) refractory to metronidazole." | 3.79 | Severe anaphylaxis caused by orally administered vancomycin to a patient with Clostridium difficile infection. ( Bossé, D; Cantin, AM; Lemire, C; Ménard, F; Ruel, J; Valiquette, L, 2013) |
| " We experienced a 13 year-old male who was taking low-dose methotrexate for juvenile rheumatoid arthritis complained diarrhea and abdominal pain for 3 weeks." | 3.76 | [A case of pseudomembranous colitis in a juvenile rheumatoid arthritis patient taking methotrexate]. ( Ahn, HJ; Choi, KY; Kim, NY; Kim, SW; Lee, HM; Lee, HN; Yu, JH, 2010) |
| " We describe a patient who developed hemorrhagic colitis shortly after starting a course of amoxicillin therapy for sinusitis prophylaxis." | 3.74 | Amoxicillin-associated hemorrhagic colitis in the presence of Klebsiella oxytoca. ( Ernst, ME; Philbrick, AM, 2007) |
| " Cox proportional hazards models were used to compare metronidazole-treated and vancomycin-treated patients in terms of time to resolution of diarrhea and time to reduction of C." | 3.74 | Comparison of clinical and microbiological response to treatment of Clostridium difficile-associated disease with metronidazole and vancomycin. ( Al-Nassir, WN; Bobulsky, GS; Donskey, CJ; Jump, RL; Nerandzic, MM; Sethi, AK, 2008) |
| "This report documents the occurrence of torsades de pointes (TdP) caused by marked QT interval prolongation in the case of a 71-year-old woman receiving both metronidazole and amiodarone for the treatment of pseudomembranous colitis and paroxysmal atrial fibrillation." | 3.73 | QT interval prolongation and torsades de pointes due to a coadministration of metronidazole and amiodarone. ( Efraimidis, M; Kardaras, F; Kounas, SP; Letsas, KP; Sideris, A, 2005) |
| " The patient did not respond adequately to oral metronidazole, as evidenced by his continuing diarrhea." | 3.73 | Vancomycin-induced elevation of liver enzyme levels. ( Cadle, RM; Darouiche, RO; Mansouri, MD, 2006) |
| "After receiving different broad-spectrum antibiotics over seven weeks the patient developed Clostridium difficile toxin-positive diarrhea that resolved after administration of oral metronidazole and Saccharomyces boulardii (Perenterol ((R)))." | 3.72 | [Fungemia after oral treatment with Saccharomyces boulardii in a patient with multiple comorbidities]. ( Lestin, F; Pertschy, A; Rimek, D, 2003) |
| " difficile colitis who received intravenous metronidazole as initial monotherapy." | 3.71 | Intravenous metronidazole for the treatment of Clostridium difficile colitis. ( Fernandez, A; Friedenberg, F; Kaul, V; Levine, GM; Niami, P, 2001) |
| "We describe a 54-year-old man with Helicobacter pylori (+) duodenal ulcer who developed Clostridium difficile associated colitis, 5 days after commencing a 'triple' regimen consisting of omeprazole 20 mg b." | 3.70 | Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori. ( Archimandritis, A; Katsorida, M; Souyioultzis, S; Tzivras, M, 1998) |
| "Current guidelines for control of Clostridium difficile infection (CDI) suggest that contact precautions be discontinued after diarrhea resolves." | 2.75 | Persistence of skin contamination and environmental shedding of Clostridium difficile during and after treatment of C. difficile infection. ( Al-Nassir, WN; Bobulsky, GS; Donskey, CJ; Nerandzic, MM; Sethi, AK, 2010) |
| "Thirty-four patients received metronidazole at a dosage of 250 mg 4 times per day for 10 days, 40 patients received nitazoxanide at a dosage of 500 mg 2 times per day for 7 days, and 36 patients received nitazoxanide at a dosage of 500 mg 2 times per day for 10 days." | 2.72 | Nitazoxanide for the treatment of Clostridium difficile colitis. ( Dupont, HL; Gupta, A; Hamill, RJ; Lentnek, A; Logan, N; Musher, DM; Rossignol, JF, 2006) |
| "Vancomycin was significantly more effective in clearing C." | 2.70 | Breaking the cycle: treatment strategies for 163 cases of recurrent Clostridium difficile disease. ( Elmer, GW; McFarland, LV; Surawicz, CM, 2002) |
| "Patients with CKD/ESRD have a higher risk of initial episode, recurrence, and development of severe CDI than those without CKD or ESRD." | 2.61 | Clostridioides difficile Infection in Chronic Kidney Disease/End-Stage Renal Disease. ( Ramesh, MS; Yee, J, 2019) |
| "Metronidazole was the most used antibiotic." | 2.58 | Variable spectrum of disease and risk factors of peripartum Clostridium difficile infection: report of 14 cases from French hospitals and literature review. ( Barbut, F; Collignon, A; Corvec, S; de Curraize, C; El-Helali, N; Fihman, V; Le Monnier, A; Rousseau, C, 2018) |
| "Vancomycin was found to be more effective than metronidazole for achieving symptomatic cure." | 2.55 | Antibiotic treatment for Clostridium difficile-associated diarrhoea in adults. ( Evans, CT; Nelson, RL; Suda, KJ, 2017) |
| "More failures and recurrence with metronidazole have led to treatment algorithms suggesting its use for mild infections and switching to vancomycin if there is no clinical improvement." | 2.52 | Controversies Around Epidemiology, Diagnosis and Treatment of Clostridium difficile Infection. ( Marra, F; Ng, K, 2015) |
| " In addition, there was no significant difference in the rate of adverse events (AEs) between metronidazole and vancomycin (OR = 1." | 2.52 | Efficacy and Safety of Metronidazole Monotherapy versus Vancomycin Monotherapy or Combination Therapy in Patients with Clostridium difficile Infection: A Systematic Review and Meta-Analysis. ( Li, R; Lin, Y; Liu, X; Lu, L; Wang, M, 2015) |
| "20 percent of the patients have recurrence after metronidazole or vancomycin treatment, and each recurrence increases the chance of a further one." | 2.49 | [Clostridium difficile infection: epidemiology, disease burden and therapy]. ( Baji, P; Banai, J; Brodszky, V; Gulácsi, L; Kertész, A; Kopcsóné Németh, I; Ludwig, E; Péntek, M; Prinz, G; Reményi, P; Strbák, B; Zsoldiné Urbán, E, 2013) |
| "Metronidazole has been applied as the first-line treatment, while vancomycin has been used in recurring cases of the disease." | 2.49 | [Fecal transfusion as treatment of Clostridium difficile infection]. ( Anttila, VJ; Arkkila, P; Mattila, E, 2013) |
| "The article reviews a pathogenesis of Pseudomembranous colitis." | 2.49 | [Pseudomembranous colitis: pathogenesis, prevention, treatment]. ( Fil', TS; Zakharova, NV, 2013) |
| "Relapse is frequent and must be distinguished from reinfection." | 2.45 | [Clostridium-difficile-associated diarrhea]. ( Bujanda, L; Cosme, A, 2009) |
| "However, if the first recurrence is characterized as severe, vancomycin should be used." | 2.45 | Recurrent Clostridium difficile infection: a review of risk factors, treatments, and outcomes. ( Johnson, S, 2009) |
| "Metronidazole has been recommended as initial therapy since the late 1990s and continues to be the first choice for all but seriously ill patients and those with complicated or fulminant infections or multiple recurrences of CDI, for whom vancomycin is recommended." | 2.44 | Treatment of Clostridium difficile infection. ( Gerding, DN; Muto, CA; Owens, RC, 2008) |
| "Rarely, pseudomembranous colitis, a severe complication of CDAD, must be treated through surgical intervention." | 2.44 | Current and future treatment modalities for Clostridium difficile-associated disease. ( Halsey, J, 2008) |
| "Little is known about acute renal failure as a consequence of Clostridium difficile-associated diarrhea." | 2.43 | Clostridium difficile causing acute renal failure: case presentation and review. ( Arrich, J; Domanovits, H; Konnaris, C; Laggner, AN; Mullner, M; Sengolge, G; Sodeck, GH, 2005) |
| " Data from clinical trials suggest that poorly absorbed antimicrobials might have a decreased risk of causing AAD and Clostridium difficile-associated disease, as concluded from studies of antibiotics used for preoperative bowel decontamination and poorly absorbed antibiotics used for traveler's diarrhea." | 2.43 | Antibiotic-associated diarrhea and pseudomembranous colitis: are they less common with poorly absorbed antimicrobials? ( Surawicz, CM, 2005) |
| "Oral vancomycin is an option for patients who cannot take or fail treatment with oral metronidazole." | 2.43 | Past, present, and future therapies for Clostridium difficile-associated disease. ( Cicogna, CE; Kuyumjian, AG; Surowiec, D; Wynd, MA, 2006) |
| "Pseudomembranous colitis was seen in the first patient during endoscopy but an enzyme immunoassay of the faeces was false negative for Clostridium difficile enterotoxin." | 2.41 | [Diarrhea due to Clostridium difficile toxin in hemato-oncological patients]. ( Kerst, JM; Kuijper, EJ; van der Lelie, J, 2001) |
| "Rifampin therapy is an infrequently reported cause of pseudomembranous colitis." | 2.40 | Delayed onset of pseudomembranous colitis after rifampin therapy. ( Byrd, RP; Fields, CL; Ossorio, MA; Roy, TM, 1997) |
| "Pseudomembranous colitis is commonly associated with the use of antibiotics but may follow administration of other drugs and has occurred in patients who have not received any medication." | 2.39 | Antibiotic-induced diarrhea and pseudomembranous colitis. ( Jacobs, NF, 1994) |
| "Metronidazole has proven to be a useful and inexpensive antibiotic for the treatment of T." | 2.38 | Metronidazole. ( Hager, WD; Rapp, RP, 1992) |
| "This series analysed 20 cases of pseudomembranous colitis diagnosed at Chang Gung Memorial Hospital between January 1985 and December 1989." | 2.38 | [Pseudomembranous colitis: a clinical analysis and review of literatures]. ( Changchien, CS; Chen, PC; Chiu, CT; Chuah, SK; Lin, HH; Wu, CS, 1991) |
| "Pseudomembranous colitis is caused by release of toxins from Clostridium difficile when it colonizes the large intestine." | 2.37 | Treatment of pseudomembranous colitis and antibiotic-associated diarrhoea. ( Burdon, DW, 1984) |
| "BACKGROUND Pseudomembranous colitis (PMC) is an opportunistic, nosocomial infection caused by Clostridium difficile." | 1.56 | Successful Treatment of Pseudomembranous Colitis with Fecal Microbiota Transplantation - A Case Study on A Patient Rescued by Extracorporeal Cardiopulmonary Resuscitation After Cardiac Arrest. ( Bai, Y; Huang, GQ; Liu, J; Sun, ZQ, 2020) |
| " difficile infection after TB medication was not low considering the relatively low TB medication dosage compared to other antibiotics." | 1.43 | Incidence and Clinical Outcomes of Clostridium difficile Infection after Treatment with Tuberculosis Medication. ( Huh, KC; Jang, BI; Jung, Y; Kim, SH; Koo, HS; Lee, SW; Lee, YM; Moon, HS; Shin, JE; Yoon, SM, 2016) |
| "Few studies have focused on multiple recurrences." | 1.43 | Clinical and Healthcare Burden of Multiple Recurrences of Clostridium difficile Infection. ( Abou Chakra, CN; Marcil-Héguy, A; Nault, V; Pépin, J; Sheitoyan-Pesant, C; Valiquette, L, 2016) |
| "This case report highlights encephalopathy as a complication of prolonged metronidazole treatment, which has become more common in clinical practice for the treatment of C." | 1.42 | Metronidazole-induced encephalopathy after prolonged metronidazole course for treatment of C. difficile colitis. ( Dapaah-Afriyie, K; Finn, A; Godfrey, MS; Zainah, H, 2015) |
| "Treatment with metronidazole has been associated with increased clinical failure rates; however, the reasons for this are unclear." | 1.42 | Age-Stratified Treatment Response Rates in Hospitalized Patients with Clostridium difficile Infection Treated with Metronidazole. ( Aitken, SL; Garey, KW; Luce, AM; Musick, WL; Pham, VP; Roux, RK; Ruppelt, SC; Wei, W, 2015) |
| "Cadazolid is a new oxazolidinone-type antibiotic that is currently in clinical development for treatment of CDAD." | 1.40 | In vitro and in vivo antibacterial evaluation of cadazolid, a new antibiotic for treatment of Clostridium difficile infections. ( Chen, X; Enderlin, M; Fournier, E; Hubschwerlen, C; Keck, W; Kelly, CP; Klenk, A; Locher, HH; Pfaff, P; Ritz, D; Schroeder, S; Seiler, P, 2014) |
| "Clostridium difficile infection is considered a major cause of nosocomial diarrhoea in developed countries and is increasingly becoming more important as an etiologic agent of community diarrhoea, also in patients without risk factors." | 1.40 | [Epidemiology of Clostridium difficile-associated disease (CDAD) in Salamanca]. ( Calvo-García, N; de Frutos-Serna, M; García-Sánchez, JE; Hernández-Egido, S; María-Blázquez, A; Siller-Ruiz, M, 2014) |
| "Hence the diagnosis of pseudomembranous colitis became apparent." | 1.40 | Emphysematous cystitis due to recurrent Clostridium difficile infection. ( Dees, A; Jonkman, JG; van Genderen, ME; van Rijn, M, 2014) |
| "CT abdomen confirmed the diagnosis of typhlitis, demonstrating characteristic terminal ileum, caecal and right-sided colon involvement." | 1.39 | Concomitant typhlitis and Clostridium difficile colitis developed after first R-CHOP chemotherapy in a non-Hodgkin lymphoma patient. ( Buppajarntham, S; Junpaparp, P; Madueno, FV; Varadi, G, 2013) |
| "Leukocytosis is a sign of severe CDI and is predictive for a complicated course." | 1.39 | [Case report. Leukocytosis in the course of Clostridium difficile infection]. ( Defosse, JM; Sakka, SG; Wappler, F; Weber, KS, 2013) |
| "Treatment with metronidazole, vancomycin or both for 10 or more days did not prevent recurrences." | 1.39 | Predictors of first recurrence in Clostridium difficile-associated disease. A study of 306 patients hospitalized in a Romanian tertiary referral center. ( Cioara, A; Filipescu, I; Flonta, M; Lupse, M; Todor, N, 2013) |
| "Vancomycin treatment of infected mice was associated with improved clinical, diarrhea, and histopathology scores and survival during treatment." | 1.39 | Vancomycin treatment's association with delayed intestinal tissue injury, clostridial overgrowth, and recurrence of Clostridium difficile infection in mice. ( Guerrant, RL; Hoffman, PS; Kolling, GL; Li, Y; Moore, JH; Riggins, MS; van Opstal, EJ; Warren, CA, 2013) |
| "The most frequent cause of pseudomembranous colitis is Clostridium difficile (C." | 1.39 | Atypical presentation of pseudomembranous colitis localized in adenomatous polyps. ( Alvarez-Lobos, M; Barra-Carrasco, J; Guzmán, AM; Hernández-Rocha, C; Lezcano, G; Paredes-Sabja, D; Zoroquiaín, P, 2013) |
| "Busulfan is a bifunctional alkylating agent widely used in pretransplant conditioning regimens in patients undergoing stem cell transplantation for hematologic malignancies." | 1.37 | Busulfan and metronidazole: an often forgotten but significant drug interaction. ( Andersson, BS; Culotta, KS; Gulbis, AM; Jones, RB, 2011) |
| "Metronidazole was the initial therapeutic regimen for 83 (96." | 1.36 | Clostridium difficile infection at a medical center in southern Taiwan: incidence, clinical features and prognosis. ( Chang, CM; Chen, PL; Chung, CH; Hung, YP; Ko, WC; Lee, CC; Lee, HC; Lee, NY; Wu, CJ; Yan, JJ, 2010) |
| "Since 2002, an epidemic of Clostridium difficile infections has occurred in southern Quebec, Canada." | 1.35 | Clostridium difficile infections in a Canadian tertiary care hospital before and during a regional epidemic associated with the BI/NAP1/027 strain. ( Béliveau, C; Labbé, AC; Laverdière, M; Louie, T; Maccannell, D; Pépin, J; Poirier, L; Savoie, M, 2008) |
| "Metronidazole was the most active antimicrobial agent against C." | 1.35 | In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin. ( Baines, SD; Freeman, J; O'Connor, R; Wilcox, MH, 2008) |
| "Oral metronidazole has been recommended for treatment of mild-to-moderate Clostridium difficile-associated disease (CDAD), in part because of concern that use of vancomycin may be more likely to promote colonization and transmission of vancomycin-resistant enterococci (VRE)." | 1.35 | Skin and environmental contamination with vancomycin-resistant Enterococci in patients receiving oral metronidazole or oral vancomycin treatment for Clostridium difficile-associated disease. ( Al-Nassir, WN; Donskey, CJ; Nerandzic, MM; Sethi, AK, 2009) |
| "Metronidazole failure was defined as persistent diarrhea after 10 days of therapy or a change of therapy to vancomycin." | 1.35 | A prospective study of risk factors and historical trends in metronidazole failure for Clostridium difficile infection. ( Cloud, J; Dreisbach, V; Hu, MY; Katchar, K; Kelly, CP; Kyne, L; Maroo, S; Noddin, L; Tummala, S, 2008) |
| "Antibiotics-associated pseudomembranous colitis is well documented and caused by abnormal overgrowth of toxin producing Clostridium difficile colonizing the large bowel of patients undergoing antibiotic therapy." | 1.35 | [A case of pseudomenbranous colitis after paclitaxel and carboplatin chemotherapy]. ( Moon, W; Yang, SW, 2009) |
| "Bortezomib has the boronic acid moiety which improves the specificity of proteasome inhibition and can be used as non-beta-lactam-based beta-lactamase inhibitors." | 1.34 | Pseudomembranous colitis following bortezomib therapy in a myeloma patient. ( Kim, CC; Kim, M; Kim, Y; Lee, DG; Lee, JW; Lee, S; Min, CK; Min, WS; Moon, SJ; Park, G, 2007) |
| "He had had recent chemotherapy for Merkel cell carcinoma of the right ear." | 1.34 | Use of intravenous immunoglobulin for the treatment of severe Clostridium difficile colitis. ( Hassoun, A; Ibrahim, F, 2007) |
| "Secondary outcome was recurrence within 60 days." | 1.34 | Outcomes of Clostridium difficile-associated disease treated with metronidazole or vancomycin before and after the emergence of NAP1/027. ( Brazeau, I; Gagnon, S; Pépin, J; Routhier, S; Valiquette, L, 2007) |
| "The frequency of recurrences within 60 days after the initial diagnosis was measured using Kaplan-Meier analysis, and Cox regression was used for multivariate analysis." | 1.33 | Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada. ( Alary, ME; Bourassa, C; Fulop, K; Godin, D; Pepin, J; Raiche, E; Ruel, J; Valiquette, L, 2005) |
| "difficile toxin, leukocytosis also tended to resolve during empiric therapy with metronidazole; some of these patients may have had C." | 1.32 | Clostridium difficile infection in patients with unexplained leukocytosis. ( Goldsmith, EA; Marino, BJ; Musher, DM; Wanahita, A, 2003) |
| "We report a case pf pseudomembranous colitis that developed in a patient with tuberculous abdominal lymphadenopathy during treatment with rifampicin." | 1.32 | A case of rifampicin induced pseudomembraneous colitis. ( Akbar, DH; Al-Huzali, AM; Al-Shehri, HZ; Falatah, HI, 2003) |
| "Pseudomembranous colitis is a well-recognized cause of diarrhea in patients receiving antibiotics and has significant consequences in terms of morbidity, mortality and cost." | 1.32 | Clinical manifestations and outcome of Pseudomembranous colitis in an elderly population in Israel. ( Ben Baruch, E; Kline, Z; Konikoff, F; Moshe, G; Moshkowitz, M; Shimoni, Z, 2004) |
| "Diarrhea is common in oncology patients; if it becomes chronic and relapsing, it can be debilitating, hinder planned management, and be difficult to treat." | 1.32 | Probiotics in relapsing and chronic diarrhea. ( Benchimol, EI; Mack, DR, 2004) |
| "Despite the high initial success rates, recurrence of CDAD remains a significant problem in 20% to 30% of cases, with increased cost and substantial morbidity." | 1.32 | Clostridium difficile-associated diarrhea: risk factors, diagnostic methods, and treatment. ( Oldfield, EC, 2004) |
| "Diarrhea is a common complication of high-dose chemotherapy and hematopoietic stem cell transplantation (HSCT)." | 1.31 | Rarity of toxigenic Clostridium difficile infections after hematopoietic stem cell transplantation: implications for symptomatic management of diarrhea. ( Gordon, L; Mehta, J; Singhal, S; Tallman, M; Tomblyn, M; Williams, S; Winter, J, 2002) |
| "We report convulsions induced by short-term metronidazole therapy used in conventional doses for Clostridium difficile colitis in an elderly patient with chronic renal failure." | 1.31 | Convulsions induced by metronidazole treatment for Clostridium difficile-associated disease in chronic renal failure. ( Beloosesky, Y; Grinblat, J; Grosman, B; Marmelstein, V, 2000) |
| "Factors associated with recurrences include endogenous reinfection by spore formation, selective IgG1 or IgA deficiency or infection with mutated strains of Clostridium difficile." | 1.31 | [Recurrent Clostridium difficile enterocolitis]. ( Ballmer, PE; Bergamin, B; Hess, T; Imoberdorf, R; Jost, R, 2000) |
| "Colonoscopy revealed a picture of pseudomembranous colitis, and Clostridium difficile toxin was positive." | 1.31 | Pseudomembranous colitis without diarrhea presenting clinically as acute intestinal pseudo-obstruction. ( Pauly, MP; Sheikh, RA; Trudeau, WL; Yasmeen, S, 2001) |
| "Bacteremia was associated with a abscess of the anal margin." | 1.31 | [Clostridium difficile bacteremia]. ( Blanckaert, K; Cattoen, C; Duthilly, A; Simon, M; Thielemans, B, 2001) |
| "Metronidazole exposure was found to be a significant risk in four of five studies that specifically assessed this variable, but the indication for metronidazole use was not specified." | 1.30 | Is there a relationship between vancomycin-resistant enterococcal infection and Clostridium difficile infection? ( Gerding, DN, 1997) |
| "Oral metronidazole was the treatment for 632 (70%) of 908 patients (1% intolerance, 2% failure, 7% relapse) and oral vancomycin was given to 122 (13%) of 908 patients (1% intolerance, 1% failure, 10% relapse)." | 1.29 | Ten years of prospective Clostridium difficile-associated disease surveillance and treatment at the Minneapolis VA Medical Center, 1982-1991. ( Gerding, DN; Lee, JT; Olson, MM; Shanholtzer, CJ, 1994) |
| "difficile diarrhea is at least as likely to resolve with antibiotic therapy in patients with AIDS as it is in those with the non-AIDS-related disorder." | 1.29 | Clostridium difficile diarrhea in patients with AIDS versus non-AIDS controls. Methods of treatment and clinical response to treatment. ( Borucki, MJ; Clench, MH; Cozart, JC; Kalangi, SS; Pollard, RB; Soloway, RD; Taylor, DR, 1993) |
| "Oral vancomycin was given alone in 41 (36%) patients, metronidazole was used in 36 (32%) patients, and a combination was given in 15 (13%) patients." | 1.29 | The clinical spectrum of Clostridium difficile colitis in immunocompromised patients. ( Schweitzer, MA; Silver, DL; Stellato, TA; Sweiss, I, 1996) |
| "Four cases are reported of pseudomembranous colitis (PMC) that developed 1 to 18 months (mean, 8 months) after definitive surgery for Hirschsprung's disease (Soave endorectal pull-though, 2; Duhamel procedure, 2)." | 1.28 | Pseudomembranous colitis following resection for Hirschsprung's disease. ( Bagwell, CE; Langham, MR; Mahaffey, SM; Shandling, B; Talbert, JL, 1992) |
| "Acute abdomen was the presenting manifestation of pseudomembranous colitis in six men who had previously been treated with antibiotics and presented with abdominal distention, pain, fever, and leukocytosis with absent or mild diarrhea." | 1.28 | Acute abdomen as the first presentation of pseudomembranous colitis. ( Hallstone, AE; Triadafilopoulos, G, 1991) |
| "Pseudomembranous colitis is not a rare complication of antibiotic therapy." | 1.28 | [Pseudomembranous colitis caused by antibiotic therapy during aorto-iliac surgery]. ( Barile, C; Conforti, M; Merlo, M; Violato, F, 1990) |
| " Vancomycin dosage ranged from 125 to 500 mg four times daily for an average of about ten days." | 1.27 | Treatment of antibiotic-associated colitis with vancomycin. ( Buggy, B; Deery, HG; Fekety, R; Silva, J, 1984) |
| "Pathological examination showed pseudomembranous colitis confined to the cecum." | 1.27 | Localized pseudomembranous colitis simulating carcinoma of the cecum. ( Amir, G; Arber, N; Nissan, S; Udassin, R; Zamir, O, 1987) |
| "Oral metronidazole is an effective, cheap, alternative to vancomycin therapy." | 1.27 | Changing epidemiology, diagnosis, and treatment of Clostridium difficile toxin-associated colitis. ( Beart, RW; Talbot, RW; Walker, RC, 1986) |
| "Metronidazole was the most active (MIC for 90% of the isolates [MIC90], 0." | 1.27 | In vitro susceptibility of Clostridium difficile to new beta-lactam and quinolone antibiotics. ( Bartlett, KH; Cheng, N; Chow, AW, 1985) |
| "Nine cases of pseudomembranous colitis (PMC) were observed during a 20-month period." | 1.26 | Pseudomembranous colitis. Treatment by metronidazole. ( Douzinas, EE; Nicolopoulos, NG; Stathapoulos, EN; Vassilakis, JS, 1981) |
| "Metronidazole was initiated at a dose of 500 mg orally three times daily and continued for 10 days." | 1.26 | Treatment of antibiotic-associated pseudomembranous colitis with metronidazole. ( Johnson, TA; Page, CO; Tabbut, BR, 1981) |
| "In established pseudomembranous colitis treatment consists of oral vancomycin (2 g/day), cholestyramine and, if necessary, intensive intravenous regimen." | 1.26 | [Antibiotic-induced pseudomembranous Clostridium difficile colitis. A new etiopathogenetically definable infectious disease]. ( Werner, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (15.75) | 18.7374 |
| 1990's | 55 (13.75) | 18.2507 |
| 2000's | 137 (34.25) | 29.6817 |
| 2010's | 138 (34.50) | 24.3611 |
| 2020's | 7 (1.75) | 2.80 |
| Authors | Studies |
|---|---|
| Hecht, DW | 1 |
| Galang, MA | 1 |
| Sambol, SP | 1 |
| Osmolski, JR | 1 |
| Johnson, S | 10 |
| Gerding, DN | 13 |
| Labbé, AC | 1 |
| Poirier, L | 1 |
| Maccannell, D | 1 |
| Louie, T | 1 |
| Savoie, M | 1 |
| Béliveau, C | 1 |
| Laverdière, M | 1 |
| Pépin, J | 5 |
| Karlowsky, JA | 1 |
| Laing, NM | 1 |
| Zhanel, GG | 2 |
| Yin, N | 1 |
| Li, J | 1 |
| He, Y | 1 |
| Herradura, P | 1 |
| Pearson, A | 1 |
| Mesleh, MF | 1 |
| Mascio, CT | 1 |
| Howland, K | 1 |
| Steenbergen, J | 1 |
| Thorne, GM | 1 |
| Citron, D | 1 |
| Van Praagh, AD | 1 |
| Mortin, LI | 1 |
| Keith, D | 1 |
| Silverman, J | 1 |
| Metcalf, C | 1 |
| Stephenson, AL | 1 |
| Dai, J | 1 |
| Gong, J | 1 |
| Guo, R | 1 |
| Kim, HS | 1 |
| Kim, HM | 1 |
| Gweon, TG | 1 |
| Prieto de Paula, JM | 1 |
| García Colodro, JÁ | 1 |
| Prieto Dehesa, M | 1 |
| Franco Hidalgo, S | 1 |
| Saunders, M | 1 |
| Jeffery, J | 1 |
| Vincent, Z | 1 |
| Ayling, RM | 1 |
| Lewis, S | 2 |
| Huang, GQ | 1 |
| Bai, Y | 1 |
| Sun, ZQ | 1 |
| Liu, J | 1 |
| AbdelKhalek, A | 1 |
| Seleem, MN | 1 |
| Preisig, D | 1 |
| Varum, F | 1 |
| Bravo, R | 1 |
| Hartig, C | 1 |
| Spleiss, J | 1 |
| Abbes, S | 1 |
| Caobelli, F | 1 |
| Wild, D | 1 |
| Puchkov, M | 1 |
| Huwyler, J | 1 |
| Haschke, M | 1 |
| Sylva, D | 1 |
| Villa, P | 1 |
| García, C | 1 |
| Pérez, JC | 1 |
| Agudelo, CA | 1 |
| Berger, FK | 1 |
| Rasheed, SS | 1 |
| Araj, GF | 1 |
| Mahfouz, R | 1 |
| Rimmani, HH | 1 |
| Karaoui, WR | 1 |
| Sharara, AI | 1 |
| Dbaibo, G | 1 |
| Becker, SL | 1 |
| von Müller, L | 1 |
| Bischoff, M | 1 |
| Matar, GM | 1 |
| Gärtner, B | 1 |
| Dow, DE | 1 |
| Seed, PC | 1 |
| Mullish, BH | 1 |
| Williams, HR | 1 |
| Wolfe, C | 1 |
| Pagano, P | 1 |
| Pillar, CM | 1 |
| Shinabarger, DL | 2 |
| Boulos, RA | 1 |
| Kodadek, LM | 1 |
| Lipsett, PA | 1 |
| de Curraize, C | 1 |
| Rousseau, C | 1 |
| Corvec, S | 1 |
| El-Helali, N | 1 |
| Fihman, V | 1 |
| Barbut, F | 5 |
| Collignon, A | 2 |
| Le Monnier, A | 1 |
| Calaway, AC | 1 |
| Jacob, JM | 1 |
| Tong, Y | 1 |
| Shumaker, L | 1 |
| Kitley, W | 1 |
| Boris, RS | 1 |
| Cary, C | 1 |
| Kaimakliotis, H | 1 |
| Masterson, TA | 1 |
| Bihrle, R | 1 |
| Koch, MO | 1 |
| Apelt, N | 1 |
| Thompson, E | 1 |
| Brown, E | 1 |
| Schindel, D | 1 |
| Sedigh Ebrahim-Saraie, H | 1 |
| Heidari, H | 1 |
| Amanati, A | 1 |
| Bazargani, A | 1 |
| Alireza Taghavi, S | 1 |
| Nikokar, I | 1 |
| Kalantar, K | 1 |
| Motamedifar, M | 1 |
| Rancich, M | 1 |
| Roman, C | 1 |
| Ramesh, MS | 1 |
| Yee, J | 1 |
| Debast, SB | 1 |
| Bauer, MP | 1 |
| Sanders, IM | 1 |
| Wilcox, MH | 10 |
| Kuijper, EJ | 5 |
| Surawicz, CM | 7 |
| Brandt, LJ | 2 |
| Binion, DG | 1 |
| Ananthakrishnan, AN | 2 |
| Curry, SR | 1 |
| Gilligan, PH | 1 |
| McFarland, LV | 3 |
| Mellow, M | 1 |
| Zuckerbraun, BS | 2 |
| Mathur, H | 1 |
| O'Connor, PM | 1 |
| Hill, C | 1 |
| Cotter, PD | 1 |
| Ross, RP | 1 |
| Junpaparp, P | 1 |
| Buppajarntham, S | 1 |
| Madueno, FV | 1 |
| Varadi, G | 1 |
| Strauss, R | 1 |
| Neurath, MF | 1 |
| Brodszky, V | 2 |
| Gulácsi, L | 2 |
| Ludwig, E | 2 |
| Prinz, G | 3 |
| Banai, J | 2 |
| Reményi, P | 2 |
| Strbák, B | 2 |
| Kertész, A | 2 |
| Kopcsóné Németh, I | 2 |
| Zsoldiné Urbán, E | 2 |
| Baji, P | 2 |
| Péntek, M | 2 |
| Parmar, SR | 1 |
| Bhatt, V | 1 |
| Yang, J | 1 |
| Zhang, Q | 1 |
| Schuster, M | 1 |
| Weber, KS | 1 |
| Defosse, JM | 1 |
| Wappler, F | 1 |
| Sakka, SG | 1 |
| Clutter, DS | 1 |
| Dubrovskaya, Y | 1 |
| Merl, MY | 1 |
| Teperman, L | 1 |
| Press, R | 1 |
| Safdar, A | 1 |
| Park, SW | 1 |
| Choi, AR | 1 |
| Lee, HJ | 2 |
| Chung, H | 1 |
| Park, JC | 1 |
| Shin, SK | 1 |
| Lee, SK | 1 |
| Lee, YC | 1 |
| Kim, JE | 1 |
| Lee, H | 1 |
| Motzkus-Feagans, C | 1 |
| Pakyz, AL | 2 |
| Ratliff, SM | 1 |
| Bajaj, JS | 1 |
| Lapane, KL | 1 |
| Hung, YP | 2 |
| Lin, HJ | 1 |
| Wu, TC | 1 |
| Liu, HC | 1 |
| Lee, JC | 1 |
| Lee, CI | 1 |
| Wu, YH | 1 |
| Wan, L | 1 |
| Tsai, PJ | 1 |
| Ko, WC | 3 |
| Kılıç, A | 1 |
| Arkkila, P | 2 |
| Mattila, E | 2 |
| Anttila, VJ | 2 |
| Jury, LA | 1 |
| Tomas, M | 1 |
| Kundrapu, S | 1 |
| Sitzlar, B | 1 |
| Donskey, CJ | 5 |
| Ebigbo, A | 1 |
| Messmann, H | 1 |
| Weis, S | 1 |
| John, E | 1 |
| Lippmann, N | 1 |
| Mössner, J | 1 |
| Lübbert, C | 1 |
| Locher, HH | 2 |
| Seiler, P | 2 |
| Chen, X | 2 |
| Schroeder, S | 1 |
| Pfaff, P | 2 |
| Enderlin, M | 1 |
| Klenk, A | 1 |
| Fournier, E | 1 |
| Hubschwerlen, C | 1 |
| Ritz, D | 2 |
| Kelly, CP | 9 |
| Keck, W | 1 |
| Lupse, M | 1 |
| Flonta, M | 1 |
| Cioara, A | 1 |
| Filipescu, I | 1 |
| Todor, N | 1 |
| Álvarez-Pérez, S | 2 |
| Blanco, JL | 2 |
| Martínez-Nevado, E | 1 |
| Peláez, T | 4 |
| Harmanus, C | 3 |
| Kuijper, E | 2 |
| García, ME | 2 |
| Seufferlein, T | 1 |
| Kleger, A | 1 |
| Nitschmann, S | 1 |
| Smith, S | 1 |
| Koon, HW | 1 |
| Ho, S | 1 |
| Hing, TC | 1 |
| Cheng, M | 1 |
| Ichikawa, Y | 1 |
| Pothoulakis, C | 1 |
| Saffouri, G | 1 |
| Khanna, S | 2 |
| Estes, L | 1 |
| Pardi, D | 1 |
| Moura, I | 1 |
| Monot, M | 1 |
| Tani, C | 1 |
| Spigaglia, P | 1 |
| Barbanti, F | 1 |
| Norais, N | 1 |
| Dupuy, B | 1 |
| Bouza, E | 6 |
| Mastrantonio, P | 2 |
| Zakharova, NV | 1 |
| Fil', TS | 1 |
| Siller-Ruiz, M | 1 |
| Calvo-García, N | 1 |
| Hernández-Egido, S | 1 |
| María-Blázquez, A | 1 |
| de Frutos-Serna, M | 1 |
| García-Sánchez, JE | 1 |
| Cornely, OA | 1 |
| Nathwani, D | 1 |
| Ivanescu, C | 1 |
| Odufowora-Sita, O | 1 |
| Retsa, P | 1 |
| Odeyemi, IA | 1 |
| de Castro, CG | 1 |
| Ganc, AJ | 1 |
| Ganc, RL | 1 |
| Petrolli, MS | 1 |
| Hamerschlack, N | 1 |
| Herzog, T | 1 |
| Deleites, C | 1 |
| Belyaev, O | 1 |
| Chromik, AM | 1 |
| Uhl, W | 1 |
| van Genderen, ME | 1 |
| Jonkman, JG | 1 |
| van Rijn, M | 1 |
| Dees, A | 1 |
| Keller, JJ | 1 |
| Godfrey, MS | 1 |
| Finn, A | 1 |
| Zainah, H | 1 |
| Dapaah-Afriyie, K | 1 |
| Joundi, RA | 1 |
| Wong, BM | 1 |
| Leis, JA | 1 |
| Lai, MJ | 1 |
| Chiueh, TS | 1 |
| Huang, ZY | 1 |
| Lin, JC | 1 |
| Demel, SL | 1 |
| Jovin, TG | 1 |
| Jadhav, AP | 1 |
| Stollman, N | 1 |
| Smith, M | 1 |
| Giovanelli, A | 1 |
| Mendolia, G | 1 |
| Burns, L | 1 |
| Didyk, E | 1 |
| Burgess, J | 1 |
| Noh, A | 1 |
| Edelstein, C | 1 |
| Alm, E | 1 |
| Kassam, Z | 1 |
| Khanafer, N | 1 |
| Blais, L | 1 |
| Hirschel, B | 1 |
| Vanhems, P | 1 |
| Rokas, KE | 2 |
| Johnson, JW | 2 |
| Beardsley, JR | 2 |
| Ohl, CA | 2 |
| Luther, VP | 2 |
| Williamson, JC | 2 |
| Marra, F | 1 |
| Ng, K | 1 |
| Pham, VP | 1 |
| Luce, AM | 1 |
| Ruppelt, SC | 1 |
| Wei, W | 1 |
| Aitken, SL | 1 |
| Musick, WL | 1 |
| Roux, RK | 1 |
| Garey, KW | 2 |
| Snydman, DR | 1 |
| McDermott, LA | 1 |
| Jacobus, NV | 1 |
| Thorpe, C | 1 |
| Stone, S | 1 |
| Jenkins, SG | 1 |
| Goldstein, EJ | 2 |
| Patel, R | 3 |
| Forbes, BA | 1 |
| Mirrett, S | 1 |
| Lee, YM | 1 |
| Huh, KC | 1 |
| Yoon, SM | 1 |
| Jang, BI | 1 |
| Shin, JE | 1 |
| Koo, HS | 1 |
| Jung, Y | 1 |
| Kim, SH | 1 |
| Moon, HS | 1 |
| Lee, SW | 1 |
| Matta, SK | 1 |
| Greenberg, A | 1 |
| Singh, A | 1 |
| Li, R | 1 |
| Lu, L | 1 |
| Lin, Y | 1 |
| Wang, M | 1 |
| Liu, X | 1 |
| Enderlin-Paput, M | 1 |
| Weiss, M | 1 |
| Clozel, M | 1 |
| Sheitoyan-Pesant, C | 1 |
| Abou Chakra, CN | 1 |
| Marcil-Héguy, A | 1 |
| Nault, V | 1 |
| Valiquette, L | 4 |
| Cares, K | 1 |
| El-Baba, M | 1 |
| Popa, D | 1 |
| Laszlo, M | 1 |
| Ciobanu, L | 1 |
| Ucenic, E | 1 |
| Mihalache, M | 1 |
| Pascu, O | 1 |
| Young, BE | 1 |
| Ochi, H | 1 |
| Marimuthu, K | 1 |
| Gibbs, HG | 1 |
| Kim, SC | 1 |
| Seo, MY | 1 |
| Lee, JY | 1 |
| Kim, KT | 1 |
| Cho, E | 1 |
| Kim, MG | 1 |
| Jo, SK | 1 |
| Cho, WY | 1 |
| Kim, HK | 1 |
| Torrijo Gómez, I | 1 |
| Uribe Quintana, N | 1 |
| Catalá Llosa, J | 1 |
| Raga Vázquez, J | 1 |
| Sellés Dechent, R | 1 |
| Martín Dieguez, MC | 1 |
| Báguena Requena, G | 1 |
| Asencio Arana, F | 1 |
| Wiedel, N | 1 |
| Gilbert, J | 1 |
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| Gupta, A | 2 |
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| Van Schooneveld, TC | 1 |
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| Nyre, LM | 1 |
| Méneret, A | 1 |
| Tassart, M | 1 |
| Khalil, A | 1 |
| Roques, S | 1 |
| Bachmeyer, C | 1 |
| Barker, HC | 1 |
| Haworth, CS | 1 |
| Williams, D | 1 |
| Roberts, P | 1 |
| Bilton, D | 1 |
| O'Connor, R | 2 |
| Baines, SD | 4 |
| Freeman, J | 4 |
| Jiang, ZD | 1 |
| Yadav, Y | 1 |
| Mullins, B | 1 |
| Wong, K | 1 |
| Dupont, HL | 2 |
| Cercenado, E | 1 |
| Alcalá, L | 3 |
| Marín, M | 1 |
| Martín-López, A | 1 |
| Martínez-Alarcón, J | 1 |
| Catalán, P | 1 |
| Sánchez-Somolinos, M | 1 |
| Fawley, WN | 2 |
| Calfee, DP | 1 |
| Nomura, K | 1 |
| Fujimoto, Y | 1 |
| Yamashita, M | 1 |
| Morimoto, Y | 1 |
| Ohshiro, M | 1 |
| Sato, K | 1 |
| Oyake, T | 1 |
| Kowata, S | 1 |
| Konishi, H | 1 |
| Yoshikawa, T | 1 |
| Ishida, Y | 1 |
| Taniwaki, M | 1 |
| Burman, LG | 2 |
| Prassler, R | 1 |
| Sethi, AK | 4 |
| Al-Nassir, WN | 4 |
| Nerandzic, MM | 3 |
| Riddle, DJ | 2 |
| Dubberke, ER | 2 |
| Hu, MY | 1 |
| Maroo, S | 1 |
| Kyne, L | 3 |
| Cloud, J | 1 |
| Tummala, S | 1 |
| Katchar, K | 1 |
| Dreisbach, V | 1 |
| Noddin, L | 1 |
| Madisch, A | 1 |
| Balassiano, IT | 2 |
| Miranda, KR | 2 |
| Boente, RF | 2 |
| Pauer, H | 1 |
| Oliveira, IC | 1 |
| Santos-Filho, J | 1 |
| Amorim, EL | 1 |
| Caniné, GA | 1 |
| Souza, CF | 1 |
| Gomes, MZ | 1 |
| Ferreira, EO | 2 |
| Brazier, JS | 2 |
| Domingues, RM | 2 |
| Bujanda, L | 1 |
| Cosme, A | 1 |
| Hames, A | 1 |
| Perry, JD | 1 |
| Gould, FK | 1 |
| Paz, Z | 1 |
| Altman, A | 1 |
| Wang, Y | 1 |
| Shen, B | 1 |
| Williams, RN | 1 |
| Hemingway, D | 1 |
| Miller, AS | 1 |
| Byun, TJ | 1 |
| Han, DS | 1 |
| Ahn, SB | 1 |
| Cho, HS | 2 |
| Kim, TY | 1 |
| Eun, CS | 1 |
| Jeon, YC | 1 |
| Sohn, JH | 1 |
| Kang, JO | 2 |
| Bakken, JS | 1 |
| Bartlett, JG | 5 |
| Koo, JS | 1 |
| Choi, WS | 1 |
| Park, DW | 1 |
| Scheppach, W | 1 |
| Bobulsky, GS | 2 |
| Yang, SW | 1 |
| Moon, W | 1 |
| Causey, MW | 1 |
| Spencer, MP | 1 |
| Steele, SR | 1 |
| Lu, CL | 1 |
| Liu, CY | 1 |
| Liao, CH | 1 |
| Huang, YT | 2 |
| Wang, HP | 1 |
| Hsueh, PR | 2 |
| Lowy, I | 1 |
| Molrine, DC | 1 |
| Leav, BA | 1 |
| Blair, BM | 1 |
| Baxter, R | 1 |
| Nichol, G | 1 |
| Thomas, WD | 1 |
| Leney, M | 1 |
| Sloan, S | 1 |
| Hay, CA | 1 |
| Ambrosino, DM | 1 |
| Baker, SS | 1 |
| Faden, H | 1 |
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| Jacobs, R | 1 |
| Pons, VG | 1 |
| McKenna, JP | 1 |
| Chamovitz, BN | 1 |
| Ehringhaus, C | 1 |
| Dominick, HC | 1 |
| Schüller, M | 1 |
| Foulke, GE | 1 |
| Williams, RK | 1 |
| de Louvois, J | 1 |
| Guzman, R | 1 |
| Kirkpatrick, J | 1 |
| Forward, K | 1 |
| Lim, F | 1 |
| Narchi, H | 1 |
| Beattie, TJ | 1 |
| Taylor, RG | 1 |
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| Azmy, AF | 1 |
| Kleinfeld, DI | 1 |
| Sharpe, RJ | 1 |
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| Bingley, PJ | 1 |
| Harding, GM | 1 |
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| Barclay, F | 1 |
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| Bonnycastle, M | 1 |
| de Dios García Díaz, J | 1 |
| Moreno Sánchez, D | 1 |
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| Medina Asensio, J | 1 |
| Goh, KL | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Washed Microbiota Transplantation for The Treatment of Oncotherapy-Related Intestinal Complications[NCT04721041] | 40 participants (Anticipated) | Interventional | 2020-10-16 | Recruiting | |||
| Assessment Of Changes In Gut Microbiota Of Patients With Recurrent Clostridioides Difficile Infection After Fecal Microbiota Transplantation: Prospective Study[NCT05739825] | 20 participants (Anticipated) | Observational | 2023-02-13 | Recruiting | |||
| Secondary Prophylaxis With Oral Vancomycin for Clostridium Difficile Recurrence: A Randomized Control Study[NCT03200093] | Phase 4 | 65 participants (Actual) | Interventional | 2017-06-08 | Terminated (stopped due to Low recruitment due to few eligible participants.) | ||
| Oral Vancomyin for Primary Clostridium Difficile Infection Prophylaxis in Patients Receiving High-Risk Antibiotics[NCT02951702] | Phase 4 | 51 participants (Actual) | Interventional | 2016-11-30 | Completed | ||
| Initial Vancomycin Taper for the Prevention of Recurrent Clostridium Difficile Infection[NCT04138706] | Phase 3 | 552 participants (Anticipated) | Interventional | 2020-11-19 | Recruiting | ||
| Prevention of Clostridium Difficile-associated Diarrhea by Daily Intake of Kefir[NCT02707198] | Phase 2 | 2 participants (Actual) | Interventional | 2015-11-30 | Terminated (stopped due to Study was not feasible to complete at study site) | ||
| Clostridioides Difficile Infection: Prospective Cohort Analyzing CLInic Evolution and Bacterial Clearance[NCT06030245] | 100 participants (Anticipated) | Observational | 2023-09-18 | Recruiting | |||
| Randomized Double Blind Controlled Trial for the Treatment of Nucleic Acid Amplification Test (NAAT)+/Toxin Enzyme Immunoassay (EIA)- Clostridium Difficile in the Hematology Oncology Population[NCT03030248] | Phase 2 | 9 participants (Actual) | Interventional | 2018-06-01 | Completed | ||
| Seroprevalence of Antibodies to Surface Antigens and Toxins of Clostridioides Difficile[NCT05192148] | 840 participants (Anticipated) | Interventional | 2021-11-30 | Recruiting | |||
| A Phase II Randomized, Double-Blind, Placebo-Controlled Study of the Clinical Effectiveness of a Human Monoclonal Antibody to Clostridium Difficile Toxin A (GS-CDA1) and a Human Monoclonal Antibody to Clostridium Difficile Toxin B (MDX-1388) in Patients B[NCT00350298] | Phase 2 | 200 participants (Actual) | Interventional | 2006-07-20 | Completed | ||
| The Comparison of the Adjuvant Effect of Probiotics Between Delivery Via Colonoscopic Spray and Oral Administration in Patients With Clostridioides Difficile Colitis Receiving Vancomycin Treatment[NCT05770726] | 60 participants (Anticipated) | Interventional | 2023-04-21 | Not yet recruiting | |||
| Fecal Microbiota Transplantation Versus Standard Medical Therapy for Initial Treatment of Recurrent Clostridium Difficile Infection[NCT02255305] | Phase 2 | 6 participants (Actual) | Interventional | 2015-01-31 | Terminated (stopped due to Due to personnel issues for finding and enrolling patients, performing appropriate follow-up and performing FMT procedure) | ||
| Comparative Study of 2 Weeks Versus 4 Weeks Treatment With Vancomycin for Clostridium Difficile Colitis[NCT00861887] | 0 participants (Actual) | Interventional | 2009-02-28 | Withdrawn (stopped due to Difficult enrollment) | |||
| Phase III,Randomized,Double-blinded Clinical Trial to Evaluate the Effectiveness and Safety of Oral Vancomycin Vs Placebo in the Prevention of Recurrence of C.Difficile Infection in Patients Under Treatment With Systemic Antibiotic Therapy[NCT05320068] | Phase 3 | 108 participants (Anticipated) | Interventional | 2022-08-02 | Recruiting | ||
| [NCT01560832] | 188 participants (Actual) | Observational | 2011-12-31 | Completed | |||
| Prospective, Randomized Study of Oral Metronidazole vs. Oral Metronidazole and Rifampin for Treatment of Clostridium Difficile-associated Diarrhea (CDAD)[NCT00182429] | Phase 3 | 100 participants | Interventional | 2004-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The incidence of clostridium difficile infection as detected for GDH/toxin positive or PCR if the GDH/toxin is equivocal. (NCT02951702)
Timeframe: Within 4 weeks from the completion of antibiotic treatment
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 2 |
| Vancomycin | 0 |
This is the time from the start of antibiotics to the diagnosis of clostridium difficile. (NCT02951702)
Timeframe: Within 4 weeks from completion of antibiotic treatment
| Intervention | days (Mean) |
|---|---|
| Control | 2 |
| Vancomycin | 0 |
Severity as defined by the IDSA/SHEA guidelines (mild to moderate, defined as white-cell count less than 15,000 cells/µL or increase in serum creatinine (SCr) by <1.5 times the baseline; severe, defined as white-cell count greater than 15,000 cells/µL or increase in SCr by >1.5 times the baseline; and fulminant, defined as the criteria above for severe with shock, hypotension, ileus, or megacolon) (NCT02951702)
Timeframe: Within 4 weeks from completion of antibiotic treatment
| Intervention | participants (Number) | |
|---|---|---|
| Mild-Mod | Severe | |
| Control | 1 | 1 |
| Vancomycin | 0 | 0 |
Determine if the addition of C. difficile toxin A and toxin B human monoclonal anti-toxin antibodies to standard of care treatment reduces the number of subjects with recurrent CDAD compared to standard of care and placebo. Standard of care treatment is defined as receipt of either metronidazole by mouth or parenterally or receipt of vancomycin by mouth with a standard duration of treatment defined as 10 - 14 days (+ 2 days)). Recurrence of CDAD is defined as the development of a new episode of C. difficile disease associated with a positive C. difficile stool toxin(s) test after the resolution of prior episode and after discontinuation of SOC treatment. (NCT00350298)
Timeframe: Day 0 to Day 84
| Intervention | Participants (Count of Participants) |
|---|---|
| GS-CDA1/MDX-1388 | 7 |
| Placebo | 25 |
Determine if the addition of a C. difficile toxin A human monoclonal antibody combined with C. difficile toxin B human monoclonal antibody to standard of care treatment reduces the number of patients with severe C. difficile disease compared to those patients receiving standard of care and placebo. Severe initial disease is defined as ≥ 5 unformed stools/day for 2 consecutive days from day 1 to the end of the initial episode of diarrhea and discontinuation of SOC. (NCT00350298)
Timeframe: Day 0 to Day 84
| Intervention | Participants (Number) |
|---|---|
| GS-CDA1/MDX-1388 | 29 |
| Placebo | 37 |
Determine if the addition of a C. difficile toxin A human monoclonal antibody combined with C. difficile toxin B human monoclonal antibody to standard of care treatment reduces the number of patients who experience standard of care treatment failure compared to those patients receiving standard of care and placebo. Standard of care treatment failure is defined as (i) recurrence of diarrhea (after it had initially resolved) while on SOC treatment during the first 14 days, or (ii) change in SOC treatment (i.e., antibiotics given), or (iii) diarrhea episode lasting ≥14 days while on SOC treatment. (NCT00350298)
Timeframe: Day 0 to Day 84
| Intervention | Participants (Number) |
|---|---|
| GS-CDA1/MDX-1388 | 21 |
| Placebo | 24 |
Determine if the addition of a C. difficile toxin A human monoclonal antibody combined with C. difficile toxin B human monoclonal antibody to standard of care treatment reduces the time to resolution of diarrhea in patients with CDAD compared to those patients receiving standard of care and placebo. Resolution of CDAD is defined as the cessation of diarrhea for at least two consecutive days. (NCT00350298)
Timeframe: Day 0 to Day 84
| Intervention | Days (Median) |
|---|---|
| GS-CDA1/MDX-1388 | 3 |
| Placebo | 3 |
Antibody concentrations to Toxin A and to Toxin B in those patients receiving C. difficile toxin A human monoclonal antibody combined with C. difficile toxin B human monoclonal antibody and standard of care treatment to those patients receiving standard of care and placebo (NCT00350298)
Timeframe: Day 0 to Day 84
| Intervention | AUC0-∞ (hours x μg/ml) (Mean) | |
|---|---|---|
| GS-CDA1 (Toxin A) | MDX-1388 (Toxin B) | |
| GS-CDA1/MDX-1388 | 115197.1 | 98540.9 |
| Placebo | NA | NA |
Safety and tolerability of a C. difficile toxin A human monoclonal antibody combined with a human monoclonal antibody to C. difficile toxin B in patients receiving standard of care treatment for C. difficile associated disease (CDAD) compared to those patients receiving standard of care and placebo reporting system organ class (SOC) MedDRA V.9.0 (NCT00350298)
Timeframe: Day 0 to Day 84
| Intervention | Adverse Events (Number) | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Blood And Lymphatic System Disorders | Cardiac Disorders | Ear and Labyrinth | Endocrine Disorders | Eye Disorder | Gastrointestinal Disorders | General Disorders | Hepatobiliary Disorders | Immune Disorders | Infections And Infestations | Injury, Poisoning And Procedural Complications | Investigations | Metabolism And Nutrition Disorders | Musculoskeletal And Connective Tissue Disorders | Neoplasms Benign, Malignant And Unspecified (Incl Cysts And Polyps) | Nervous System Disorders | Psychiatric Disorders | Renal And Urinary Disorders | Reproductive System And Breast Disorders | Respiratory, Thoracic And Mediastinal Disorders | Skin And Subcutaneous Tissue Disorders | Surgical And Medical Procedures | Vascular Disorders | |
| GS-CDA1/MDX-1388 | 30 | 13 | 3 | 0 | 7 | 312 | 91 | 1 | 1 | 68 | 9 | 18 | 55 | 37 | 3 | 61 | 11 | 9 | 6 | 36 | 27 | 4 | 9 |
| Placebo | 41 | 20 | 3 | 1 | 7 | 395 | 128 | 1 | 0 | 83 | 19 | 30 | 128 | 46 | 1 | 79 | 36 | 9 | 1 | 61 | 17 | 3 | 19 |
Patients' length of stay post-procedure will be measured (NCT02255305)
Timeframe: 90 days
| Intervention | days (Mean) |
|---|---|
| FMT Group (Intervention Arm) | 22 |
| Antimicrobial Group (Control Arm) | 6.5 |
Number of patients who died from any cause within 90 days of randomization (NCT02255305)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| FMT Group (Intervention Arm) | 0 |
| Antimicrobial Group (Control Arm) | 0 |
Number of patients with resolution of diarrhea and other abdominal symptoms or return to baseline symptoms that were present prior to C. difficile diagnosis (NCT02255305)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| FMT Group (Intervention Arm) | 1 |
| Antimicrobial Group (Control Arm) | 0 |
Number of patients re-admitted to the hospital for recurrent Clostridium difficile infection (NCT02255305)
Timeframe: 90 days
| Intervention | participants (Number) |
|---|---|
| FMT Group (Intervention Arm) | 1 |
| Antimicrobial Group (Control Arm) | 1 |
Amount of time it takes for patient to have cessation of diarrhea and abdominal pain/gastrointestinal symptoms (or return to baseline) and normalization of white blood cell count, creatinine, and temperature. (NCT02255305)
Timeframe: 90 days
| Intervention | days (Number) |
|---|---|
| FMT Group (Intervention Arm) | 44 |
88 reviews available for metronidazole and Enterocolitis, Pseudomembranous
| Article | Year |
|---|---|
Real-world comparison of fidaxomicin versus vancomycin or metronidazole in the treatment of Clostridium difficile infection: a systematic review and meta-analysis.
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridium Infections; Enterocolitis, Pseudomembranous; Fid | 2022 |
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Diarrhea; Enterocolitis, Ps | 2018 |
Prevention and Treatment of Clostridium difficile Enterocolitis.
Topics: Clostridioides difficile; Colectomy; Cross Infection; Drug Therapy, Combination; Enterocolitis, Pseu | 2018 |
Variable spectrum of disease and risk factors of peripartum Clostridium difficile infection: report of 14 cases from French hospitals and literature review.
Topics: Anti-Bacterial Agents; Cesarean Section; Clostridioides difficile; Clostridium Infections; Enterocol | 2018 |
Updated guidelines for diagnosing and managing Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Fecal Microbiota T | 2019 |
Clostridioides difficile Infection in Chronic Kidney Disease/End-Stage Renal Disease.
Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antimicrobial Stewardship; Broadly Neutralizing Antib | 2019 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
[Antimicrobial therapy of Clostridium difficile infection. Systematic review and meta-analysis of the scientific evidence].
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enteroc | 2013 |
[Clostridium difficile infection: epidemiology, disease burden and therapy].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Cost | 2013 |
[Clostridium difficile infection: epidemiology, risk factors, pathogenesis, clinical features, diagnosis and therapy].
Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Enterocolitis | 2013 |
[Fecal transfusion as treatment of Clostridium difficile infection].
Topics: Anti-Infective Agents; Enterocolitis, Pseudomembranous; Feces; Finland; Humans; Intubation, Gastroin | 2013 |
[Pseudomembranous colitis: pathogenesis, prevention, treatment].
Topics: Anti-Bacterial Agents; Clostridioides difficile; Drug Therapy, Combination; Enterocolitis, Pseudomem | 2013 |
Clinical efficacy of fidaxomicin compared with vancomycin and metronidazole in Clostridium difficile infections: a meta-analysis and indirect treatment comparison.
Topics: Aminoglycosides; Anti-Bacterial Agents; Clinical Trials, Phase III as Topic; Clostridioides difficil | 2014 |
Treatment of recurrent and severe Clostridium difficile infection.
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; F | 2015 |
Controversies Around Epidemiology, Diagnosis and Treatment of Clostridium difficile Infection.
Topics: Aminoglycosides; Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Fecal Microbiota Transplant | 2015 |
Efficacy and Safety of Metronidazole Monotherapy versus Vancomycin Monotherapy or Combination Therapy in Patients with Clostridium difficile Infection: A Systematic Review and Meta-Analysis.
Topics: Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Clostridioides difficile; Drug Therapy, | 2015 |
Antibiotic treatment for Clostridium difficile-associated diarrhoea in adults.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Bacitracin; Clostridioides difficile; Diarrhea; Enter | 2017 |
Peripartum Clostridium difficile infection: case series and review of the literature.
Topics: Adult; Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Hum | 2008 |
Clostridium difficile: a reemerging pathogen.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Colectomy; Communicable Diseases, Emerging; C | 2008 |
Clostridium difficile infection in solid organ transplant recipients.
Topics: Animals; Anti-Bacterial Agents; Clostridioides difficile; Digestive System Surgical Procedures; Ente | 2008 |
[Diagnostics and therapy of chronic diarrhea in elderly people].
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents; Antidiarrheal | 2008 |
[Clostridium-difficile-associated diarrhea].
Topics: Aged; Anti-Bacterial Agents; Bacterial Toxins; Biological Therapy; Clostridioides difficile; Colecto | 2009 |
A 76-year-old man with recurrent Clostridium difficile-associated diarrhea: review of C. difficile infection.
Topics: Aged; Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Diarrhea; Enterocolitis, Ps | 2009 |
Recurrent Clostridium difficile infection: causality and therapeutic approaches.
Topics: Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Humans; Immunother | 2009 |
Recurrent Clostridium difficile infection: a review of risk factors, treatments, and outcomes.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Cross Infection; Diarrhea; Entero | 2009 |
Clostridium difficile infection in the intensive care unit.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enterocolitis, Pseudomem | 2009 |
[Infections with Clostridium difficile following antibiotic therapy].
Topics: Administration, Oral; Algorithms; Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides diffi | 2009 |
Clostridium difficile enteritis after colectomy.
Topics: Adult; Anti-Bacterial Agents; Colectomy; Enterocolitis, Pseudomembranous; Female; Humans; Ileostomy; | 2009 |
[Clostridium-difficile-associated infections].
Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Base Sequence; Clostridioides difficile | 2010 |
Clostridium difficile and the surgeon.
Topics: Anti-Infective Agents; Clostridioides difficile; Colectomy; Enterocolitis, Pseudomembranous; Feces; | 2010 |
Diagnosis, management, and prevention of Clostridium difficile infection in long-term care facilities: a review.
Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enterocolitis, Pse | 2010 |
Clostridium difficile bacteremia, Taiwan.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteremia; Child; Clostridioides difficile; Enteroc | 2010 |
Clostridium difficile: an update for the primary care clinician.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enterocolitis, Pseudomem | 2010 |
Management of Clostridium difficile infection: thinking inside and outside the box.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antibodies, Bacterial; Antibodies, Monoclonal; Antitoxins; C | 2010 |
Clostridium difficile infection: epidemiology, risk factors and management.
Topics: Clostridioides difficile; Colitis; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Prevalenc | 2011 |
Clostridium difficile: progress and challenges.
Topics: Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Enterocolitis, Pseudomembranous; Fec | 2010 |
Treatment of refractory and recurrent Clostridium difficile infection.
Topics: Clostridioides difficile; Colectomy; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Recurre | 2011 |
Clinical approach to severe Clostridium difficile infection: update for the hospital practitioner.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseudomembran | 2011 |
Clostridium difficile infection in older adults: a review and update on its management.
Topics: Aged; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Clost | 2012 |
Meeting the challenge of recurrent Clostridium difficile infection.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; | 2012 |
Current strategies for management of initial Clostridium difficile infection.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enter | 2012 |
Novel management strategies in the treatment of severe Clostridium difficile infection.
Topics: Algorithms; Anti-Infective Agents; Colectomy; Enterocolitis, Pseudomembranous; Humans; Ileostomy; Im | 2012 |
Epidemiology, diagnosis and treatment of Clostridium difficile infection.
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; F | 2012 |
[Treatment of infections associated with Clostridium difficile].
Topics: Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Drug Resistance; Enterocolitis, Pseudomem | 2003 |
Clostridium difficile causing acute renal failure: case presentation and review.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Enter | 2005 |
Clostridium difficile--associated diarrhea.
Topics: Aged; Algorithms; Anti-Infective Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudome | 2005 |
Antibiotic-associated diarrhea and pseudomembranous colitis: are they less common with poorly absorbed antimicrobials?
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Clinical Trials as Topic; Clostridioides difficile; D | 2005 |
Clinical manifestations, treatment and control of infections caused by Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; | 2005 |
Treatment of Clostridium difficile-associated disease: old therapies and new strategies.
Topics: Anti-Infective Agents; Bacterial Toxins; Clostridioides difficile; Cross Infection; Enterocolitis, P | 2005 |
Clostridium difficile associated diarrhoea: diagnosis and treatment.
Topics: Administration, Oral; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Drug Resistance; En | 2005 |
Past, present, and future therapies for Clostridium difficile-associated disease.
Topics: Clostridioides difficile; Enterocolitis, Pseudomembranous; Forecasting; Humans; Metronidazole; Probi | 2006 |
Clostridium difficile-associated disease.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Enzyme Inhibitors; | 2006 |
Diagnosis of colitis: making the initial diagnosis.
Topics: Acute Disease; Adult; Biopsy, Needle; Clostridioides difficile; Clostridium Infections; Early Diagno | 2007 |
Antibiotic treatment for Clostridium difficile-associated diarrhea in adults.
Topics: Adult; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; F | 2007 |
Clostridium difficile.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Beclomethasone; Biopsy; Budesonide; Clostridioides | 2007 |
Treatment of Clostridium difficile infection.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Disease Management; Enterocolitis, Pseudomembranous | 2008 |
Current and future treatment modalities for Clostridium difficile-associated disease.
Topics: Anti-Bacterial Agents; Bacterial Vaccines; Clostridioides difficile; Clostridium Infections; Cross I | 2008 |
The case for vancomycin as the preferred drug for treatment of Clostridium difficile infection.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; History, 20th Cent | 2008 |
Necrotising enteritis--a review.
Topics: Ampicillin; Ascariasis; Clostridium perfringens; Enterocolitis, Pseudomembranous; Germany; Humans; I | 1980 |
Pseudomembranous colitis: a case report and literature review.
Topics: Aged; Bacitracin; Enterocolitis, Pseudomembranous; Erythromycin; Female; Humans; Metronidazole; Vanc | 1984 |
Antibiotic-associated colitis.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Cholestyramine Resin; Clindamycin; Clostridium; Clostrid | 1984 |
Treatment of pseudomembranous colitis and antibiotic-associated diarrhoea.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacitracin; Diarrhea; Enterocolitis, Pseudomembranous; Female; H | 1984 |
Pseudomembranous colitis.
Topics: Anion Exchange Resins; Anti-Bacterial Agents; Clindamycin; Clostridium Infections; Cytotoxins; Enter | 1982 |
Pseudomembranous colitis: pathogenesis and therapy.
Topics: Anti-Bacterial Agents; Atropine; Bacitracin; Botulinum Toxins; Cholestyramine Resin; Clostridium; Cl | 1982 |
Rectal use of vancomycin.
Topics: Administration, Oral; Administration, Rectal; Clostridioides difficile; Enema; Enterocolitis, Pseudo | 1994 |
Update on Clostridium difficile-induced colitis, Part 1.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Humans; | 1994 |
Update on Clostridium difficile-induced colitis, Part 2.
Topics: Administration, Oral; Anti-Bacterial Agents; Capsules; Clostridioides difficile; Drug Costs; Enteroc | 1994 |
Clostridium difficile infection: a common clinical problem for the general internist.
Topics: Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Enterotoxins; Family Practice; | 1994 |
Antibiotic-induced diarrhea and pseudomembranous colitis.
Topics: Administration, Oral; Anti-Bacterial Agents; Cluster Analysis; Cross Infection; Cytotoxins; Diarrhea | 1994 |
Clostridium difficile colitis in the critically ill.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; APACHE; Colectomy; Combined Modal | 1996 |
Delayed onset of pseudomembranous colitis after rifampin therapy.
Topics: Antibiotics, Antitubercular; Antidiarrheals; Clostridioides difficile; Diagnosis, Differential; Diar | 1997 |
Clostridium difficile infection.
Topics: Administration, Oral; Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Colon; Diar | 1998 |
Treatment of Clostridium difficile infection.
Topics: Animals; Antitrichomonal Agents; Cattle; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudome | 1998 |
[Pseudomembranous colitis (Clostridium difficile infection)].
Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Clostridioides difficile; Diagnosis, Differential; Dr | 1999 |
Update on Clostridium difficile infection.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Community-Acquired Infections; Disease Outbreaks; Ente | 2000 |
Treatment of Clostridium difficile-associated diarrhea and colitis.
Topics: Abdomen, Acute; Anti-Bacterial Agents; Antidiarrheals; Clinical Trials as Topic; Clostridioides diff | 2000 |
Clostridial enterocolitis.
Topics: Animals; Bacitracin; Clostridioides difficile; Clostridium Infections; Clostridium perfringens; Dise | 2000 |
Clostridium difficile--Associated diarrhea: A review.
Topics: Clostridioides difficile; Colon; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Metronidazole; P | 2001 |
Recurrent Clostridium difficile diarrhoea.
Topics: Anion Exchange Resins; Anti-Bacterial Agents; Anti-Infective Agents; Enterocolitis, Pseudomembranous | 2001 |
[Diarrhea due to Clostridium difficile toxin in hemato-oncological patients].
Topics: Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Clostridioides difficil | 2001 |
Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; | 2001 |
[Antibiotics and pseudomembranous colitis].
Topics: Anti-Bacterial Agents; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Parenteral | 1979 |
Clostridium difficile infection: responses, relapses and re-infections.
Topics: Clinical Trials as Topic; Cross Infection; Disease Outbreaks; Enterocolitis, Pseudomembranous; Human | 1992 |
Metronidazole.
Topics: Bacterial Infections; Costs and Cost Analysis; Drug Interactions; Drug Resistance, Microbial; Entero | 1992 |
[Current status of Clostridium difficile: recent advances in diagnostic materials and treatment of colitis and diarrheas associated with antibiotic therapy].
Topics: Causality; Clinical Protocols; Colectomy; Enterocolitis, Pseudomembranous; Female; Humans; Male; Met | 1991 |
[Pseudomembranous colitis: a clinical analysis and review of literatures].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Enterocolitis, Pseudomembranous; Female; Humans; Male; M | 1991 |
Update on pseudomembranous colitis.
Topics: Enterocolitis, Pseudomembranous; Humans; Metronidazole; Patient Isolation; United States; Vancomycin | 1989 |
Necrotising enterocolitis.
Topics: Age Factors; Animals; Anti-Bacterial Agents; Bacterial Infections; Bottle Feeding; Cross Infection; | 1986 |
26 trials available for metronidazole and Enterocolitis, Pseudomembranous
| Article | Year |
|---|---|
Colonic delivery of metronidazole-loaded capsules for local treatment of bacterial infections: A clinical pharmacoscintigraphy study.
Topics: Administration, Oral; Adult; Biological Availability; Capsules; Cell-Derived Microparticles; Colon; | 2021 |
A Prospective Program to Reduce the Clinical Incidence of Clostridium difficile Colitis Infection after Cystectomy.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Asymptomatic Diseases; Clostridioides difficile | 2019 |
[Challenges of Clostridium difficile infection].
Topics: Aminoglycosides; Biodiversity; Cause of Death; Colonoscopy; Cross Infection; Disinfection; Enterocol | 2013 |
[Recurrent Clostridium difficile infection. Treatment with duodenal infusion of donor feces].
Topics: Adult; Combined Modality Therapy; Drug Resistance, Microbial; Early Termination of Clinical Trials; | 2014 |
Fecal microbiota transplant after hematopoietic SCT: report of a successful case.
Topics: Allografts; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Feces; | 2015 |
Persistence of skin contamination and environmental shedding of Clostridium difficile during and after treatment of C. difficile infection.
Topics: Aged; Aged, 80 and over; Bacterial Typing Techniques; Clostridioides difficile; Clostridium Infectio | 2010 |
Persistence of skin contamination and environmental shedding of Clostridium difficile during and after treatment of C. difficile infection.
Topics: Aged; Aged, 80 and over; Bacterial Typing Techniques; Clostridioides difficile; Clostridium Infectio | 2010 |
Persistence of skin contamination and environmental shedding of Clostridium difficile during and after treatment of C. difficile infection.
Topics: Aged; Aged, 80 and over; Bacterial Typing Techniques; Clostridioides difficile; Clostridium Infectio | 2010 |
Persistence of skin contamination and environmental shedding of Clostridium difficile during and after treatment of C. difficile infection.
Topics: Aged; Aged, 80 and over; Bacterial Typing Techniques; Clostridioides difficile; Clostridium Infectio | 2010 |
Treatment with monoclonal antibodies against Clostridium difficile toxins.
Topics: Adult; Aged; Aged, 80 and over; Antibodies; Antibodies, Monoclonal; Antitoxins; Bacterial Proteins; | 2010 |
Treatment with monoclonal antibodies against Clostridium difficile toxins.
Topics: Adult; Aged; Aged, 80 and over; Antibodies; Antibodies, Monoclonal; Antitoxins; Bacterial Proteins; | 2010 |
Treatment with monoclonal antibodies against Clostridium difficile toxins.
Topics: Adult; Aged; Aged, 80 and over; Antibodies; Antibodies, Monoclonal; Antitoxins; Bacterial Proteins; | 2010 |
Treatment with monoclonal antibodies against Clostridium difficile toxins.
Topics: Adult; Aged; Aged, 80 and over; Antibodies; Antibodies, Monoclonal; Antitoxins; Bacterial Proteins; | 2010 |
Breaking the cycle: treatment strategies for 163 cases of recurrent Clostridium difficile disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Cohort | 2002 |
Effectiveness and appropriateness of empiric metronidazole for Clostridium difficile-associated diarrhea.
Topics: Anti-Infective Agents; Diarrhea; Enterocolitis, Pseudomembranous; Female; Hospitals, Community; Hosp | 2003 |
Lactobacillus plantarum 299v for the treatment of recurrent Clostridium difficile-associated diarrhoea: a double-blind, placebo-controlled trial.
Topics: Aged; Clostridioides difficile; Double-Blind Method; Enterocolitis, Pseudomembranous; Female; Humans | 2003 |
Effect of the prebiotic oligofructose on relapse of Clostridium difficile-associated diarrhea: a randomized, controlled study.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Antidiarrheals; Bifidobacterium; Clostridioides diff | 2005 |
Nitazoxanide for the treatment of Clostridium difficile colitis.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Huma | 2006 |
Prospective, randomized inpatient study of oral metronidazole versus oral metronidazole and rifampin for treatment of primary episode of Clostridium difficile-associated diarrhea.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Diarrhea; Enterocolitis, Pseudomembranous; Female | 2006 |
Frequent emergence of resistance in Clostridium difficile during treatment of C. difficile-associated diarrhea with fusidic acid.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Double-Blind Method; Drug Resistance, Bac | 2006 |
Clostridium difficile colitis that fails conventional metronidazole therapy: response to nitazoxanide.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembr | 2007 |
Lactobacillus plantarum 299v enhances the concentrations of fecal short-chain fatty acids in patients with recurrent clostridium difficile-associated diarrhea.
Topics: Anti-Infective Agents; Biomarkers; Chromatography, Gas; Clostridioides difficile; Diarrhea; Enteroco | 2007 |
A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Clostridioides difficile; Double-Blind Met | 2007 |
A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Clostridioides difficile; Double-Blind Met | 2007 |
A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Clostridioides difficile; Double-Blind Met | 2007 |
A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Clostridioides difficile; Double-Blind Met | 2007 |
A multicentre comparison of clindamycin and metronidazole in the treatment of anaerobic infections.
Topics: Adolescent; Adult; Aged; Anaerobiosis; Bacterial Infections; Clindamycin; Enterocolitis, Pseudomembr | 1981 |
Clostridium difficile-associated diarrhea in patients with HIV positivity and AIDS: a prospective controlled study.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Clostridioides difficile; Diarrhea; Enterocoliti | 1994 |
Comparison of vancomycin, teicoplanin, metronidazole, and fusidic acid for the treatment of Clostridium difficile-associated diarrhea.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocoliti | 1996 |
Comparison of vancomycin, teicoplanin, metronidazole, and fusidic acid for the treatment of Clostridium difficile-associated diarrhea.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocoliti | 1996 |
Comparison of vancomycin, teicoplanin, metronidazole, and fusidic acid for the treatment of Clostridium difficile-associated diarrhea.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocoliti | 1996 |
Comparison of vancomycin, teicoplanin, metronidazole, and fusidic acid for the treatment of Clostridium difficile-associated diarrhea.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocoliti | 1996 |
Metronidazole may inhibit intestinal colonization with Clostridium difficile.
Topics: Adult; Aged; Anti-Bacterial Agents; Clostridioides difficile; Colorectal Surgery; Double-Blind Metho | 1998 |
Recurrent Clostridium difficile disease: epidemiology and clinical characteristics.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Enteroc | 1999 |
Treatment of asymptomatic Clostridium difficile carriers (fecal excretors) with vancomycin or metronidazole. A randomized, placebo-controlled trial.
Topics: Aged; Bacterial Typing Techniques; Carrier State; Clostridioides difficile; Clostridium Infections; | 1992 |
The role of anion-exchange resins in the treatment of antibiotic-associated pseudomembranous colitis.
Topics: Adult; Anion Exchange Resins; Child; Cholestyramine Resin; Clinical Trials as Topic; Colestipol; Dru | 1990 |
Intravenous metronidazole and Clostridium difficile-associated diarrhea or colitis.
Topics: Enterocolitis, Pseudomembranous; Humans; Metronidazole | 1989 |
Treatment of Clostridium difficile colitis.
Topics: Animals; Bacitracin; Clinical Trials as Topic; Clostridium; Clostridium Infections; Enterocolitis, P | 1985 |
286 other studies available for metronidazole and Enterocolitis, Pseudomembranous
| Article | Year |
|---|---|
In vitro activities of 15 antimicrobial agents against 110 toxigenic clostridium difficile clinical isolates collected from 1983 to 2004.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Drug Resistance, Bacterial; Enter | 2007 |
Clostridium difficile infections in a Canadian tertiary care hospital before and during a regional epidemic associated with the BI/NAP1/027 strain.
Topics: Adult; Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Community-Acqu | 2008 |
In vitro activity of OPT-80 tested against clinical isolates of toxin-producing Clostridium difficile.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Cross Infection; Enterocolitis, P | 2008 |
Structure-Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of Clostridium difficile-Associated Diarrhea.
Topics: Animals; Anti-Bacterial Agents; Clostridioides difficile; Cricetinae; Diarrhea; Enterocolitis, Pseud | 2015 |
Seeing C diff differently.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Consumer Health Information; Cost of Illness; Enter | 2022 |
Case of Pseudomembranous Colitis Caused by a
Topics: Anti-Bacterial Agents; Clostridium Infections; Colitis, Ischemic; Cytomegalovirus Infections; Diarrh | 2023 |
Clostridium difficile infection associated with metronidazole-based treatment for Helicobacter pylori eradication.
Topics: Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Female; Helicobacter Infections; Helicobacte | 2019 |
Relationship between faecal metronidazole and lactoferrin concentrations to clinical response of patients with Clostridioides difficile.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembr | 2020 |
Successful Treatment of Pseudomembranous Colitis with Fecal Microbiota Transplantation - A Case Study on A Patient Rescued by Extracorporeal Cardiopulmonary Resuscitation After Cardiac Arrest.
Topics: Adolescent; Anti-Bacterial Agents; Cardiopulmonary Resuscitation; Clostridioides difficile; Enteroco | 2020 |
Repurposing the Veterinary Antiprotozoal Drug Ronidazole for the Treatment of Clostridioides difficile Infection.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Caco-2 Cells; Cell Line, Tumor; Clostridioides | 2020 |
Pseudomembranous colitis from cytomegalovirus infection.
Topics: Antiviral Agents; Clostridioides difficile; Colonoscopy; Cytomegalovirus Infections; Diagnosis, Diff | 2017 |
Molecular characterization, toxin detection and resistance testing of human clinical Clostridium difficile isolates from Lebanon.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Clostridium Infections; Drug Resi | 2018 |
Clostridium difficile cure with fecal microbiota transplantation in a child with Pompe disease: a case report.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Fecal Mi | 2018 |
Comparison of the in vitro antibacterial activity of Ramizol, fidaxomicin, vancomycin, and metronidazole against 100 clinical isolates of Clostridium difficile by broth microdilution.
Topics: Anti-Bacterial Agents; Benzoates; Clostridioides difficile; Drug Resistance, Bacterial; Enterocoliti | 2018 |
In trauma, expect the unexpected: a rare case of post-traumatic pancreatitis associated with salmonellosis and enterocolitis.
Topics: Abdomen; Adolescent; Anti-Bacterial Agents; Ceftriaxone; Clostridioides difficile; Enterocolitis, Ps | 2018 |
A multicenter-based study on epidemiology, antibiotic susceptibility and risk factors of toxigenic Clostridium difficile in hospitalized patients in southwestern Iran.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Child; Child, Preschool; Clos | 2018 |
Antimicrobial activity of LFF571 and three treatment agents against Clostridium difficile isolates collected for a pan-European survey in 2008: clinical and therapeutic implications.
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infe | 2013 |
Analysis of anti-Clostridium difficile activity of thuricin CD, vancomycin, metronidazole, ramoplanin, and actagardine, both singly and in paired combinations.
Topics: Anti-Bacterial Agents; Bacteriocins; Clostridioides difficile; Depsipeptides; Drug Synergism; Drug T | 2013 |
Concomitant typhlitis and Clostridium difficile colitis developed after first R-CHOP chemotherapy in a non-Hodgkin lymphoma patient.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Monoclonal, Murine-Derived; Antineoplastic | 2013 |
[Clostridium difficile infections - still a major challenge].
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Colectomy; Combined Modality Thera | 2013 |
A retrospective review of metronidazole and vancomycin in the management of Clostridium difficile infection in patients with hematologic malignancies.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Endpoint Determinat | 2014 |
[Case report. Leukocytosis in the course of Clostridium difficile infection].
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Colon; Colonoscopy; Diabetes Mellitus, Type 2 | 2013 |
Fidaxomicin versus conventional antimicrobial therapy in 59 recipients of solid organ and hematopoietic stem cell transplantation with Clostridium difficile-associated diarrhea.
Topics: Adult; Aged; Aminoglycosides; Analysis of Variance; Anti-Bacterial Agents; Clinical Trials as Topic; | 2013 |
The effects of statins on the clinical outcomes of Clostridium difficile infection in hospitalised patients.
Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Fe | 2013 |
Statin use and infections in Veterans with cirrhosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseu | 2013 |
Risk factors of fecal toxigenic or non-toxigenic Clostridium difficile colonization: impact of Toll-like receptor polymorphisms and prior antibiotic exposure.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Cefepime; Cefuroxime; Cephalosporins; Clostridioides | 2013 |
A Clostridium difficile infection (CDI) stewardship initiative improves adherence to practice guidelines for management of CDI.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Guideline Adherenc | 2013 |
[Clostridium difficile infection (CDI) in the course of time - an issue only for the internist?].
Topics: Aminoglycosides; Clostridioides difficile; Colectomy; Colostomy; Cross-Sectional Studies; Drug Resis | 2014 |
In vitro and in vivo antibacterial evaluation of cadazolid, a new antibiotic for treatment of Clostridium difficile infections.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides dif | 2014 |
Predictors of first recurrence in Clostridium difficile-associated disease. A study of 306 patients hospitalized in a Romanian tertiary referral center.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides diffi | 2013 |
Shedding of Clostridium difficile PCR ribotype 078 by zoo animals, and report of an unstable metronidazole-resistant isolate from a zebra foal (Equus quagga burchellii).
Topics: Animals; Animals, Zoo; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides d | 2014 |
Editorial Commentary: the trials and tribulations of treating Clostridium difficile infection-one step backward, one step forward, but still progress.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Diarrhea; Enterocolitis, Ps | 2014 |
Intestinal microbiota transplantation: a case of Crohn's colitis with superimposed Clostridium difficile infection.
Topics: Addison Disease; Adult; Anti-Infective Agents; Clostridioides difficile; Crohn Disease; Enterocoliti | 2013 |
Fidaxomicin inhibits Clostridium difficile toxin A-mediated enteritis in the mouse ileum.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacterial Toxins; Clostri | 2014 |
Outcomes from rectal vancomycin therapy in patients with Clostridium difficile infection.
Topics: Administration, Rectal; Aged; Anti-Bacterial Agents; Clostridioides difficile; Drug Therapy, Combina | 2014 |
Multidisciplinary analysis of a nontoxigenic Clostridium difficile strain with stable resistance to metronidazole.
Topics: Anti-Infective Agents; Bacterial Proteins; Clostridioides difficile; Drug Resistance, Bacterial; Ent | 2014 |
[Epidemiology of Clostridium difficile-associated disease (CDAD) in Salamanca].
Topics: Aged; Aged, 80 and over; Antacids; Anti-Bacterial Agents; Antineoplastic Agents; Clostridioides diff | 2014 |
[Clostridium difficile in visceral surgery].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Clostridioides d | 2015 |
Emphysematous cystitis due to recurrent Clostridium difficile infection.
Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Cystitis; Emphysema; | 2014 |
Metronidazole-induced encephalopathy after prolonged metronidazole course for treatment of C. difficile colitis.
Topics: Aged; Anti-Infective Agents; Brain Diseases; Clostridioides difficile; Enterocolitis, Pseudomembrano | 2015 |
Antibiotics "just-in-case" in a patient with aspiration pneumonitis.
Topics: Anti-Bacterial Agents; Cerebral Palsy; Clostridioides difficile; Enterocolitis, Pseudomembranous; Ep | 2015 |
The first Clostridium difficile ribotype 027 strain isolated in Taiwan.
Topics: Aged; Anti-Bacterial Agents; Carcinoma, Squamous Cell; Chemoradiotherapy; Clostridioides difficile; | 2016 |
Metronidazole toxicity presenting with acute onset of aphasia and right sided weakness.
Topics: Adult; Anti-Bacterial Agents; Aphasia; Bacteremia; Clostridioides difficile; Enterocolitis, Pseudome | 2015 |
Frozen encapsulated stool in recurrent Clostridium difficile: exploring the role of pills in the treatment hierarchy of fecal microbiota transplant nonresponders.
Topics: Abdominal Pain; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Biological Therapy; | 2015 |
Treatment of Clostridium difficile infection in a French university hospital.
Topics: Adult; Aged; Clostridioides difficile; Cohort Studies; Cross Infection; Drug Therapy, Combination; E | 2015 |
Editorial Commentary: Critically Ill Patients With Clostridium difficile Infection: Are 2 Antibiotics Better Than One?
Topics: Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Ma | 2015 |
The Addition of Intravenous Metronidazole to Oral Vancomycin is Associated With Improved Mortality in Critically Ill Patients With Clostridium difficile Infection.
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Anti-Infective Agents; Clostridioide | 2015 |
Age-Stratified Treatment Response Rates in Hospitalized Patients with Clostridium difficile Infection Treated with Metronidazole.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Ma | 2015 |
U.S.-Based National Sentinel Surveillance Study for the Epidemiology of Clostridium difficile-Associated Diarrheal Isolates and Their Susceptibility to Fidaxomicin.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Toxins; Clindamycin; Clostridioides difficile; Dia | 2015 |
Incidence and Clinical Outcomes of Clostridium difficile Infection after Treatment with Tuberculosis Medication.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotics, Antitubercular; Clostridioides d | 2016 |
Diarrhea With Clostridium difficile-Positive Stool-Trick or Treat: A Teachable Moment.
Topics: Aged; Anti-Bacterial Agents; Axitinib; Carcinoma, Renal Cell; Clostridioides difficile; Costs and Co | 2015 |
Cadazolid Does Not Promote Intestinal Colonization of Vancomycin-Resistant Enterococci in Mice.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Clostridioides difficile; Colony Count, Microbial; | 2016 |
Clinical and Healthcare Burden of Multiple Recurrences of Clostridium difficile Infection.
Topics: Anti-Bacterial Agents; Canada; Clostridioides difficile; Cohort Studies; Cost of Illness; Enterocoli | 2016 |
A 9-Month-Old Presenting With Rectal Prolapse.
Topics: Clostridioides difficile; Enterocolitis, Pseudomembranous; Feces; Female; Follow-Up Studies; Humans; | 2016 |
Self-Administered Home Series Fecal "Minitransplants" for Recurrent Clostridium difficile Infection on a Rectal Remnant.
Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Colectomy; Enterocolitis, Pseudomembranous; F | 2015 |
The Uncertain Benefits of Combination Therapy for Clostridium difficile Infection.
Topics: Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Ma | 2016 |
Reply to Young, Ochi, and Marimuthu.
Topics: Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Ma | 2016 |
Advanced chronic kidney disease: a strong risk factor for Clostridium difficile infection.
Topics: Aged; Anti-Infective Agents; Chi-Square Distribution; Clostridioides difficile; Enterocolitis, Pseud | 2016 |
[Fulminant Clostridium difficile colitis].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clostridioides difficile; Colectomy; Enterocol | 2016 |
Clostridium difficile Associated Diarrhea.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Fecal Mi | 2016 |
[Antibiotic treatment of clostridial colitis].
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Drug Resistance, Bacterial; Entero | 2016 |
The efficacy of intracolonic vancomycin for severe Clostridium difficile colitis: a case series.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Colon; Drug Administration Routes; Enterocoli | 2016 |
Pseudomembranous colitis presenting as a mechanical large bowel obstruction.
Topics: Administration, Intravenous; Administration, Oral; Anastomosis, Surgical; Anti-Bacterial Agents; Clo | 2018 |
Use of intravenous tigecycline in patients with severe Clostridium difficile infection: a retrospective observational cohort study.
Topics: Administration, Intravenous; Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; C | 2016 |
[Clostridium difficile infection : What is currently available for treatment?]
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomem | 2016 |
Repeat Clostridium difficile Testing.
Topics: Abdominal Pain; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacterial Protein | 2016 |
Isolation of Clostridium difficile from dogs with digestive disorders, including stable metronidazole-resistant strains.
Topics: Animals; Anti-Infective Agents; Clostridioides difficile; Disease Reservoirs; Dog Diseases; Dogs; Dr | 2017 |
Lack of Benefit With Combination Therapy for Clostridium difficile Infection.
Topics: Academic Medical Centers; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-In | 2017 |
Community-acquired
Topics: Abdominal Pain; Anti-Bacterial Agents; Clostridioides difficile; Community-Acquired Infections; Diar | 2017 |
Real-Time Electronic Tracking of Diarrheal Episodes and Laxative Therapy Enables Verification of Clostridium difficile Clinical Testing Criteria and Reduction of Clostridium difficile Infection Rates.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Electronic Data Pr | 2017 |
Effect of telephoned notification of positive Clostridium difficile test results on the time to the ordering of antimicrobial therapy.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Disease Notification; Enterocolit | 2008 |
[A recurrent diarrhea].
Topics: Administration, Oral; Aged; Anti-Infective Agents; Clostridioides difficile; Colonoscopy; Diarrhea; | 2009 |
Clostridium difficile pancolitis in adults with cystic fibrosis.
Topics: Adult; Clostridioides difficile; Cystic Fibrosis; Drug Therapy, Combination; Enterocolitis, Pseudome | 2008 |
In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Culture Media; DNA Fingerprinting; Enterocolitis, P | 2008 |
Metronidazole resistance in Clostridium difficile is heterogeneous.
Topics: Anti-Infective Agents; Clostridioides difficile; Drug Resistance, Bacterial; Enterocolitis, Pseudome | 2008 |
Emergence of reduced susceptibility to metronidazole in Clostridium difficile.
Topics: Anti-Infective Agents; Bacterial Typing Techniques; Clostridioides difficile; Cluster Analysis; DNA, | 2008 |
Absence of pseudomembranes in Clostridium difficile-associated diarrhea in patients using immunosuppression agents.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Toxins; Clostridioides di | 2009 |
Metronidazole and vancomycin: equivalence of initial efficacy in CDAD.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Humans; Metronidaz | 2008 |
[Percutaneous endoscopic colostomy for treatment of an antibiotic-induced pseudomembranous colitis].
Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Colonoscopy; Colostomy; Enterocol | 2008 |
Skin and environmental contamination with vancomycin-resistant Enterococci in patients receiving oral metronidazole or oral vancomycin treatment for Clostridium difficile-associated disease.
Topics: Administration, Oral; Aged; Anti-Infective Agents; Clostridioides difficile; Enterococcus; Enterocol | 2009 |
A prospective study of risk factors and historical trends in metronidazole failure for Clostridium difficile infection.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Typing Techniques; Clostridioides difficile; Cohort Studie | 2008 |
Characterization of Clostridium difficile strains isolated from immunosuppressed inpatients in a hospital in Rio de Janeiro, Brazil.
Topics: Adult; Anti-Bacterial Agents; Bacterial Toxins; Bacterial Typing Techniques; Brazil; Clostridioides | 2009 |
In vitro effect of metronidazole and vancomycin in combination on Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Drug Synergism; Enterocolitis, Pseudomembranous; Hu | 2009 |
[The approach to recurrent infections with Clostridium difficile].
Topics: Anti-Bacterial Agents; Brachytherapy; Clostridioides difficile; Combined Modality Therapy; Complemen | 2008 |
Clostridium difficile-associated diarrhea in Crohn's disease patients with ostomy.
Topics: Adult; Clostridioides difficile; Colectomy; Crohn Disease; Diarrhea; Enterocolitis, Pseudomembranous | 2010 |
Enteral Clostridium difficile, an emerging cause for high-output ileostomy.
Topics: Adult; Aged; Anti-Bacterial Agents; Clostridioides difficile; Crohn Disease; Enterocolitis, Pseudome | 2009 |
[Clinical characteristics and changing epidemiology of Clostridium difficile-associated disease (CDAD)].
Topics: Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Bacterial Toxins; Cephalospo | 2009 |
Resolution of recurrent Clostridium difficile-associated diarrhea using staggered antibiotic withdrawal and kefir.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides diffici | 2009 |
Clostridium difficile infection: historic review.
Topics: Animals; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cricetinae; Entero | 2009 |
Fulminant amebic colitis mimicking pseudomembranous colitis.
Topics: Anastomosis, Surgical; Anti-Bacterial Agents; Appendectomy; Biopsy, Needle; Colonoscopy; Combined Mo | 2010 |
[A case of pseudomenbranous colitis after paclitaxel and carboplatin chemotherapy].
Topics: Aged; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, | 2009 |
Severe and refractory Clostridium difficile infection successfully treated with tigecycline and metronidazole.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Female; | 2010 |
Increasing incidence of community-associated atypical Clostridium difficile disease in children.
Topics: Biopsy, Needle; Child; Child, Preschool; Clostridioides difficile; Clostridium Infections; Colonosco | 2010 |
Fluoroquinolone resistance and Clostridium difficile, Germany.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Drug Resistance, Bacterial; Enterocolitis, Pseudome | 2010 |
[Change of Clostridium difficile colitis during recent 10 years in Korea].
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Huma | 2010 |
Clostridium difficile infection at a medical center in southern Taiwan: incidence, clinical features and prognosis.
Topics: Academic Medical Centers; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteri | 2010 |
Increase in use of vancomycin for Clostridium difficile infection in US hospitals.
Topics: Academic Medical Centers; Adult; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; E | 2010 |
Proton pump inhibitors as a risk factor for recurrence of Clostridium-difficile-associated diarrhea.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocol | 2010 |
Clostridium difficile colitis: a call for aggressive management.
Topics: Algorithms; Anti-Infective Agents; Clostridioides difficile; Drug Therapy, Computer-Assisted; Entero | 2010 |
Failure of tigecycline to treat severe Clostridium difficile infection.
Topics: Aged; Anti-Bacterial Agents; Critical Care; Drug Resistance, Bacterial; Drug Therapy, Combination; E | 2010 |
[Inflammatory bowel disease and Clostridium difficile: be prepared].
Topics: Abdominal Pain; Adult; Aged, 80 and over; Anti-Infective Agents; Diarrhea; Enterocolitis, Pseudomemb | 2010 |
Rifampin plus metronidazole for Clostridium difficile infection.
Topics: Anti-Infective Agents; Antibiotics, Antitubercular; Clostridioides difficile; Enterocolitis, Pseudom | 2010 |
[A case of pseudomembranous colitis in a juvenile rheumatoid arthritis patient taking methotrexate].
Topics: Abdominal Pain; Adolescent; Anti-Infective Agents; Antirheumatic Agents; Arthritis, Juvenile; Diagno | 2010 |
'Game changer' antibiotic and others in works for superbug.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clostridioides difficile; Enterocoliti | 2011 |
Clostridium difficile infection and treatment in the pediatric inflammatory bowel disease population.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Child; Clostridioides diffi | 2011 |
Cumulative antibiotic exposures over time and the risk of Clostridium difficile infection.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; En | 2011 |
Busulfan and metronidazole: an often forgotten but significant drug interaction.
Topics: Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Busulfan; Child; Clostridioides difficile; | 2011 |
Reducing the risk of severe complications among patients with Clostridium difficile infection.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antiprotozoal Agents; Comorbidity; Confusion; Entero | 2011 |
Antimicrobial use and risk for recurrent Clostridium difficile infection.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Dose-Response Relationship, Dr | 2011 |
Recognizing metronidazole resistant C. difficile.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Drug Resistance, Bacterial; Drug T | 2011 |
Epidemiology and clinical characteristics of Clostridium difficile infection in a Korean tertiary hospital.
Topics: Aged; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Clostridium Infections; Diarrh | 2011 |
Lack of association of outcomes with treatment duration and microbiologic susceptibility data in Clostridium difficile infections in a non-NAP1/BI/027 setting.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Drug Resistance, | 2012 |
In vitro activities of CB-183,315, vancomycin, and metronidazole against 556 strains of Clostridium difficile, 445 other intestinal anaerobes, and 56 Enterobacteriaceae species.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Clostridioides difficile; Enterobacteriaceae; Enterobact | 2012 |
Prospective observational study comparing three different treatment regimes in patients with Clostridium difficile infection.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridio | 2012 |
[Clostridium difficile. Increasing spread outside the hospital].
Topics: Ambulatory Care; Anti-Infective Agents; Clostridioides difficile; Cross Infection; Diagnosis, Differ | 2012 |
A 5-year retrospective review of experience with Clostridium difficile-associated diarrhea.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enterocolitis, Pseudomem | 2012 |
Sustained clinical response as an endpoint in treatment trials of Clostridium difficile-associated diarrhea.
Topics: Aminoglycosides; Anti-Bacterial Agents; Clinical Trials, Phase III as Topic; Clostridioides difficil | 2012 |
Chemotherapy patients with C. difficile colitis have outcomes similar to immunocompetent C. difficile patients.
Topics: Adult; Aged; Analysis of Variance; Anti-Bacterial Agents; Antineoplastic Agents; Chi-Square Distribu | 2012 |
MBX-500, a hybrid antibiotic with in vitro and in vivo efficacy against toxigenic Clostridium difficile.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Clostridioides difficile; Cricetinae; DNA Gyrase | 2012 |
A woman with community-acquired Clostridium difficile infection.
Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Community-Acquired Infections; Enterocolitis, | 2012 |
In vitro and in vivo activities of the novel Ketolide RBx 14255 against Clostridium difficile.
Topics: Animals; Anti-Bacterial Agents; Clostridioides difficile; Cricetinae; Drug Resistance, Bacterial; En | 2012 |
Severe anaphylaxis caused by orally administered vancomycin to a patient with Clostridium difficile infection.
Topics: Administration, Oral; Adult; Anaphylaxis; Anti-Bacterial Agents; Clostridioides difficile; Clostridi | 2013 |
[Clostridium-difficile-colitis: more frequent and more severe].
Topics: Adult; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Clos | 2012 |
Rifaximin in the treatment of recurrent Clostridium difficile infection.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Clostridium Infecti | 2013 |
Pseudomembranous colitis and bacteremia in an immune competent patient associated with a rare specie of Clostridium (C. ramosum).
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteremia; Ciprofloxaci | 2012 |
Vancomycin treatment's association with delayed intestinal tissue injury, clostridial overgrowth, and recurrence of Clostridium difficile infection in mice.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteroides; Cecum; Clostridioides difficile; Clost | 2013 |
[Successful treatment of life-threatening, treatment resistant Clostridium difficile infection associated pseudomembranous colitis with faecal transplantation].
Topics: Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Drug Resistance, Bacterial; | 2012 |
Atypical presentation of pseudomembranous colitis localized in adenomatous polyps.
Topics: Adenomatous Polyps; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Colonic Neop | 2013 |
Rarity of toxigenic Clostridium difficile infections after hematopoietic stem cell transplantation: implications for symptomatic management of diarrhea.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Disease Manageme | 2002 |
Pseudomembranous colitis requiring surgical intervention following triple therapy for Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Clarithromycin; Drug Therapy, Combination; Enterocol | 2002 |
[Antibiotic-associated diarrhea].
Topics: Anti-Bacterial Agents; Diarrhea; Enterocolitis, Pseudomembranous; Fluid Therapy; Humans; Metronidazo | 2003 |
Occupational exposure to cephalosporins leading to clostridium difficile infection.
Topics: Adult; Cephalosporins; Clostridioides difficile; Drug Industry; Enterocolitis, Pseudomembranous; Fem | 2003 |
Failure of intravenous linezolid to treat Clostridium difficile associated diarrhea.
Topics: Acetamides; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Dose-Response Relationship, D | 2003 |
Collagenous colitis associated with Clostridium difficile: a cause effect?
Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Clostridioides difficile; Coli | 2003 |
Bowel wall "thumbprinting" in pseudomembranous colitis.
Topics: Adult; Anti-Infective Agents; Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole; Tomogr | 2003 |
Clostridium difficile infection in patients with unexplained leukocytosis.
Topics: Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Feces; Female; Hum | 2003 |
[Fungemia after oral treatment with Saccharomyces boulardii in a patient with multiple comorbidities].
Topics: Administration, Oral; Amputation, Surgical; Clostridioides difficile; Diabetes Mellitus, Type 2; Dia | 2003 |
[Assessment of susceptibility to metronidazole and vancomycin of Clostridium difficile strains isolated between 1998-2002].
Topics: Anti-Bacterial Agents; Clostridioides difficile; Drug Resistance, Multiple, Bacterial; Enterocolitis | 2003 |
A case of rifampicin induced pseudomembraneous colitis.
Topics: Abdominal Pain; Adult; Biopsy, Needle; Colonoscopy; Dose-Response Relationship, Drug; Drug Administr | 2003 |
Clinical manifestations and outcome of Pseudomembranous colitis in an elderly population in Israel.
Topics: Adult; Aged; Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metronida | 2004 |
In-vitro activity of nisin against clinical isolates of Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2004 |
Clostridium difficile colitis in patients after kidney and pancreas-kidney transplantation.
Topics: Adult; Aged; Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Femal | 2004 |
Probiotics in relapsing and chronic diarrhea.
Topics: Anti-Infective Agents; Bone Marrow Transplantation; Child, Preschool; Chronic Disease; Clostridioide | 2004 |
Pseudomembranous colitis.
Topics: Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Vancomycin | 2004 |
Clostridium difficile-associated diarrhea: risk factors, diagnostic methods, and treatment.
Topics: Anti-Bacterial Agents; Diarrhea; Endoscopy, Gastrointestinal; Enterocolitis, Pseudomembranous; Feces | 2004 |
QT interval prolongation and torsades de pointes due to a coadministration of metronidazole and amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Infective Agents; Atrial Fibrillation; Drug Interacti | 2005 |
Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole.
Topics: Anti-Bacterial Agents; Drug Administration Schedule; Enterocolitis, Pseudomembranous; Follow-Up Stud | 2005 |
Metronidazole for Clostridium difficile-associated disease: is it okay for Mom?
Topics: Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Recurrence; Vancomyci | 2005 |
Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Enterocolitis, Pseudomembra | 2005 |
Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Enterocolitis, Pseudomembra | 2005 |
Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Enterocolitis, Pseudomembra | 2005 |
Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Enterocolitis, Pseudomembra | 2005 |
Surveillance for resistance to metronidazole and vancomycin in genotypically distinct and UK epidemic Clostridium difficile isolates in a large teaching hospital.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Drug Resistance, Bacterial; Entero | 2005 |
Molecular characterization of Clostridium difficile isolates from horses in an intensive care unit and association of disease severity with strain type.
Topics: Animals; Anti-Bacterial Agents; Bacterial Toxins; Base Sequence; Clostridioides difficile; Drug Resi | 2006 |
Vancomycin-induced elevation of liver enzyme levels.
Topics: Alanine Transaminase; Anti-Bacterial Agents; Aspartate Aminotransferases; Clostridioides difficile; | 2006 |
[Occurrence and treatment of Clostridium difficile-associated diarrhea].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pse | 2006 |
Pseudomembranous colitis presenting as an isolated colonic stricture.
Topics: Aged; Anti-Bacterial Agents; Colonic Diseases; Constriction, Pathologic; Enterocolitis, Pseudomembra | 2007 |
Management of an outbreak of Clostridium difficile-associated disease among geriatric patients.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Cross Infection; Disease O | 2006 |
Treatment of Clostridium difficile-associated disease (CDAD).
Topics: Clostridioides difficile; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Vancomycin | 2006 |
Nitazoxanide versus metronidazole for Clostridium difficile-associated colitis.
Topics: Aged; Animals; Anti-Bacterial Agents; Clostridioides difficile; Cricetinae; Enterocolitis, Pseudomem | 2007 |
Pseudomembranous colitis following bortezomib therapy in a myeloma patient.
Topics: Aged; Anti-Bacterial Agents; Antineoplastic Agents; Boronic Acids; Bortezomib; Enterocolitis, Pseudo | 2007 |
New PCR ribotypes of Clostridium difficile detected in children in Brazil: prevalent types of Clostridium difficile in Brazil.
Topics: Brazil; Child; Child, Preschool; Clindamycin; Clostridioides difficile; Electrophoresis, Polyacrylam | 2007 |
Laboratory diagnosis of antibiotic-associated diarrhea: a Polish pilot study into the clinical relevance of Clostridium difficile and Clostridium perfringens toxins.
Topics: Anti-Infective Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Clostridium p | 2007 |
[Clostridium difficile associated diarrhea in the elderly patient].
Topics: Age Factors; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Cross Inf | 2007 |
Clostridium difficile small-bowel enteritis after total proctocolectomy: a rare but fatal, easily missed diagnosis. Report of a case.
Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Enteritis; Enterocolitis, Pseudomembranous; F | 2007 |
Effect of metronidazole on growth and toxin production by epidemic Clostridium difficile PCR ribotypes 001 and 027 in a human gut model.
Topics: Aged; Animals; Anti-Infective Agents; Cecum; Chlorocebus aethiops; Clindamycin; Clostridioides diffi | 2007 |
Hospital-acquired Clostridium difficile-associated disease in the intensive care unit setting: epidemiology, clinical course and outcome.
Topics: Adult; Anti-Infective Agents; Child; Clostridioides difficile; Cohort Studies; Cross Infection; Ente | 2007 |
Use of intravenous immunoglobulin for the treatment of severe Clostridium difficile colitis.
Topics: Aged; Anti-Bacterial Agents; Carcinoma, Merkel Cell; Clostridioides difficile; Cytotoxins; Diarrhea; | 2007 |
Leukemoid reaction in pseudomembranous colitis.
Topics: Aged; Anti-Infective Agents; Enterocolitis, Pseudomembranous; Humans; Leukemoid Reaction; Male; Metr | 2007 |
A case of recurrent Clostridium difficile diarrhea.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enter | 2007 |
Lack of a physicochemical interaction between metronidazole and cholestyramine.
Topics: Anti-Bacterial Agents; Cholestyramine Resin; Drug Interactions; Enterocolitis, Pseudomembranous; Hum | 2007 |
Epidemiology of Clostridium difficile infection in a large teaching hospital in Singapore.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseu | 2007 |
Outcomes of Clostridium difficile-associated disease treated with metronidazole or vancomycin before and after the emergence of NAP1/027.
Topics: Aged; Anti-Bacterial Agents; Chi-Square Distribution; Clostridioides difficile; Enterocolitis, Pseud | 2007 |
Amoxicillin-associated hemorrhagic colitis in the presence of Klebsiella oxytoca.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Enterocolitis, Pseudomembranous; Humans; | 2007 |
The changing face of Clostridium difficile: what treatment options remain?
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Huma | 2007 |
Clostridium difficile-associated disease with lethal outcome in a 77-year-old woman. A case report.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Cholecy | 2007 |
Metronidazole-induced pancreatitis during HIV infection.
Topics: Acute Disease; Adult; Anti-Infective Agents; Enterocolitis, Pseudomembranous; HIV Infections; Homose | 2008 |
Intussusception associated with pseudomembranous colitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Child; Colonoscopy; Diagnosis, Differential; Enterocolitis, Pseu | 2008 |
Vancomycin for the treatment of Clostridium difficile Infection: for whom is this expensive bullet really magic?
Topics: Administration, Oral; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembrano | 2008 |
Both oral metronidazole and oral vancomycin promote persistent overgrowth of vancomycin-resistant enterococci during treatment of Clostridium difficile-associated disease.
Topics: Administration, Oral; Aged; Aged, 80 and over; Clostridioides difficile; Cross Infection; Enterococc | 2008 |
Clostridium difficile infection.
Topics: Adult; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Humans; Inf | 2008 |
Decreased effectiveness of metronidazole for the treatment of Clostridium difficile infection?
Topics: Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Humans; Metronidaz | 2008 |
Comparison of clinical and microbiological response to treatment of Clostridium difficile-associated disease with metronidazole and vancomycin.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Clostridioides difficile; Colony Count, Microbial | 2008 |
[Postpartum pseudomembranous colitis].
Topics: Adult; Cefotaxime; Colon; Colonoscopy; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; F | 1984 |
Vancomycin dose for pseudomembranous colitis.
Topics: Costs and Cost Analysis; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Vancomycin | 1980 |
A new approach to antibiotic therapy in colon surgery based on bioassay tissue concentrations.
Topics: Animals; Anti-Bacterial Agents; Cefoxitin; Cephamycins; Clindamycin; Colon; Dogs; Enterocolitis, Pse | 1982 |
Treatment of anaerobic infections.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Clostridium Infections; Clostridiu | 1984 |
Treatment of antibiotic-associated colitis with vancomycin.
Topics: Adult; Anti-Bacterial Agents; Bacitracin; Bacterial Proteins; Bacterial Toxins; Diarrhea; Enterocoli | 1984 |
[Clinical studies on the isolation of Clastridium difficile--13 cases].
Topics: Adult; Aged; Clostridium; Colitis, Ulcerative; Enterocolitis, Pseudomembranous; Feces; Female; Human | 1983 |
Intermittent therapy with metronidazole for relapse of pseudomembranous colitis.
Topics: Enterocolitis, Pseudomembranous; Humans; Male; Metronidazole; Recurrence | 1984 |
Pseudomembranous colitis after treatment with metronidazole.
Topics: Adolescent; Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole; Rectum | 1981 |
Pseudomembranous colitis after treatment with metronidazole.
Topics: Aged; Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole | 1981 |
Pseudomembranous colitis after treatment with metronidazole.
Topics: Enterocolitis, Pseudomembranous; Humans; Metronidazole | 1981 |
Non-Clostridium difficile pseudomembranous colitis responding to both vancomycin and metronidazole. ?
Topics: Adolescent; Clostridium; Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole; Vancomycin | 1981 |
Metronidazole and antibiotic-associated colitis.
Topics: Aged; Enterocolitis, Pseudomembranous; Humans; Male; Metronidazole; Vancomycin | 1981 |
Pseudomembranous colitis secondary to metronidazole.
Topics: Clostridium; Cytotoxins; Enterocolitis, Pseudomembranous; Feces; Humans; Male; Metronidazole; Middle | 1983 |
[Pseudomembranous colitis: observations on 13 clinical cases].
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Combinations; Drug Therapy, Combination; Enterocolitis, Pse | 1981 |
Metronidazole: an alternate therapy for antibiotic-associated colitis.
Topics: Adult; Aged; Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metronida | 1982 |
Pseudomembranous colitis unresponsive to oral vancomycin therapy.
Topics: Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole; Middle Aged; Vancomycin | 1982 |
Recurrence of antibiotic-associated pseudomembranous colitis after parenteral metronidazole therapy and cure by oral vancomycin: case report.
Topics: Administration, Oral; Aged; Enterocolitis, Pseudomembranous; Humans; Injections, Intravenous; Male; | 1981 |
Pseudomembranous colitis. Treatment by metronidazole.
Topics: Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Humans; Intestinal Mucosa; Metronidazole; Si | 1981 |
Pseudomembranous colitis: multiple relapses after treatment with metronidazole.
Topics: Aged; Cholestyramine Resin; Diarrhea; Enterocolitis, Pseudomembranous; Feces; Female; Humans; Metron | 1981 |
Treatment of antibiotic-associated pseudomembranous colitis with metronidazole.
Topics: Aged; Ampicillin; Clostridium Infections; Enterocolitis, Pseudomembranous; Humans; Male; Metronidazo | 1981 |
Antibiotic-associated colitis--an abating enigma.
Topics: Anti-Bacterial Agents; Bacitracin; Clindamycin; Clostridium Infections; Enterocolitis, Pseudomembran | 1981 |
Metronidazole: cause as well as cure for colitis.
Topics: Enterocolitis, Pseudomembranous; Humans; Metronidazole | 1981 |
Treatment and prevention of antimicrobial agent-induced colitis and diarrhae.
Topics: Animals; Anti-Bacterial Agents; Bacitracin; Cholestyramine Resin; Clostridium Infections; Cricetinae | 1980 |
Treatment of pseudomembranous colitis with oral metronidazole after relapse following vancomycin.
Topics: Clostridium Infections; Enterocolitis, Pseudomembranous; Humans; Male; Metronidazole; Middle Aged; V | 1980 |
Pseudomembranous colitis in a patient with a colostomy.
Topics: Cephalexin; Colonoscopy; Colostomy; Enterocolitis, Pseudomembranous; Humans; Male; Metronidazole; Mi | 1995 |
Ten years of prospective Clostridium difficile-associated disease surveillance and treatment at the Minneapolis VA Medical Center, 1982-1991.
Topics: Administration, Oral; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; Fe | 1994 |
Rectal prolapse in children associated with Clostridium difficile infection.
Topics: Child, Preschool; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Metroni | 1995 |
[Combatting nosocomial intestinal infections with yeasts].
Topics: Combined Modality Therapy; Cross Infection; Enterocolitis, Pseudomembranous; Humans; Metronidazole; | 1995 |
Clostridium difficile colitis: an increasing hospital-acquired illness.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cephalosporins; Child; Child, Pre | 1995 |
Fulminant pseudomembranous colitis (PMC) following triple therapy for Helicobacter pylori.
Topics: Amoxicillin; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female; Helicobacter Infect | 1994 |
Stopping an epidemic of Clostridium difficile diarrhea.
Topics: Clindamycin; Cross Infection; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Metronidazole | 1994 |
Clostridium difficile colitis.
Topics: Aged; Clostridioides difficile; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Vancomycin | 1994 |
[Survey with three epidemiological markers after 22 cases of diarrhea caused by Clostridium difficile in a geriatric hospital].
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Bacterial Proteins; Bacterial | 1993 |
The treatment of Clostridium difficile colitis.
Topics: Clostridioides difficile; Enterocolitis, Pseudomembranous; Humans; Metronidazole | 1993 |
Clostridium difficile infection is a treatable cause of diarrhea in patients with advanced human immunodeficiency virus infection: a study of seven consecutive patients admitted from 1986 to 1992 to a university teaching hospital.
Topics: Adult; AIDS-Related Opportunistic Infections; Clostridioides difficile; Diarrhea; Enterocolitis, Pse | 1993 |
Clostridium difficile diarrhea in patients with AIDS versus non-AIDS controls. Methods of treatment and clinical response to treatment.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Bacterial Toxins; Case-Control | 1993 |
The clinical spectrum of Clostridium difficile colitis in immunocompromised patients.
Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female; Humans; I | 1996 |
A multiplicity of bowel problems.
Topics: Aeromonas hydrophila; Ampicillin; Diagnosis, Differential; Drug Therapy, Combination; Enterocolitis, | 1996 |
[Occurrence and clinical picture of Clostridium difficile infections after antibiotic therapy].
Topics: Adult; Anti-Bacterial Agents; Cholestyramine Resin; Enterocolitis, Pseudomembranous; Female; Humans; | 1995 |
[85-year-old female patient with abdominal distention and fever].
Topics: Aged; Aged, 80 and over; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Fever; H | 1996 |
[Current diagnosis, clinical course and treatment of acute colitis infection with Clostridium difficile].
Topics: Adult; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Flu | 1996 |
Pseudomembranous colitis.
Topics: Administration, Oral; Anti-Infective Agents; Enterocolitis, Pseudomembranous; Humans; Metronidazole; | 1996 |
Is there a relationship between vancomycin-resistant enterococcal infection and Clostridium difficile infection?
Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus; Enterocolitis, Pseudomembranous; Gr | 1997 |
Fulminant pseudomembranous colitis leading to total colonic stricture.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Child; Colectomy; Colonic Diseases; Constriction, Path | 1997 |
Pseudomembraneous clostridium after autologous bone marrow transplantation.
Topics: Adolescent; Anti-Bacterial Agents; Antitrichomonal Agents; Bone Marrow Transplantation; Clostridioid | 1998 |
Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori.
Topics: Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Duodenal Ulcer; Enterocolitis, Pseudom | 1998 |
Clostridium difficile colitis associated with treatment of Helicobacter pylori infection.
Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Bismuth; Clostridioides difficile; Diarrhea; Enterocolitis | 1998 |
Clostridium difficile colitis: factors influencing treatment failure and relapse--a prospective evaluation.
Topics: Aged; Anti-Bacterial Agents; Case-Control Studies; Enterocolitis, Pseudomembranous; Female; Follow-U | 1998 |
Susceptibility testing of Clostridium difficile against metronidazole and vancomycin by disk diffusion and Etest.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Drug Resistance, Microbial; Enterocolitis | 1999 |
[Susceptibility of Clostridium difficile to metronidazole using the E-test: effect of the culture medium].
Topics: Animals; Blood; Clostridioides difficile; Culture Media; Enterocolitis, Pseudomembranous; Horses; Hu | 1999 |
Antimicrobial susceptibilities and serogroups of clinical strains of Clostridium difficile isolated in France in 1991 and 1997.
Topics: Adult; Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Culture Media; Diffusion; | 1999 |
[Joint manifestations related to Clostridium difficile].
Topics: Adult; Aged; Amikacin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-In | 2000 |
Convulsions induced by metronidazole treatment for Clostridium difficile-associated disease in chronic renal failure.
Topics: Aged; Anti-Infective Agents; Enterocolitis, Pseudomembranous; Female; Humans; Kidney Failure, Chroni | 2000 |
In vitro and in vivo activities of nitazoxanide against Clostridium difficile.
Topics: Animals; Anti-Bacterial Agents; Clindamycin; Clostridioides difficile; Cricetinae; Disease Models, A | 2000 |
Metronidazole resistance in Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Drug Resistance, Microbial; Enterocolitis | 2000 |
Clostridium difficile infection in allogeneic stem cell transplant recipients is associated with severe graft-versus-host disease and non-relapse mortality.
Topics: Adolescent; Adult; Cytomegalovirus Infections; Enterocolitis, Pseudomembranous; Graft vs Host Diseas | 2000 |
[Recurrent Clostridium difficile enterocolitis].
Topics: Aged; Aged, 80 and over; Clostridioides difficile; Drug Therapy, Combination; Enterocolitis, Pseudom | 2000 |
Clostridium difficile colitis following antibiotic prophylaxis for dental procedures.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Toxins; Clindamycin; Clostridioides d | 2001 |
Suspected Clostridium difficile-associated diarrhea in two cats.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clostridioides difficile; Diarrhea; Enterocoliti | 2001 |
[Pseudomembranous colitis after pristinamycin].
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Enterocolitis, Pseudomembrano | 2001 |
Clostridium difficile infection in patients with neutropenia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antineoplastic Agents; Cross Infe | 2001 |
Intravenous metronidazole for the treatment of Clostridium difficile colitis.
Topics: Adult; Aged; Aged, 80 and over; Clostridioides difficile; Colitis; Dose-Response Relationship, Drug; | 2001 |
Pseudomembranous colitis without diarrhea presenting clinically as acute intestinal pseudo-obstruction.
Topics: Aged; Anti-Infective Agents; Biopsy; Colonic Pseudo-Obstruction; Colonoscopy; Contrast Media; Diabet | 2001 |
Clinical microbiological case: a heart transplant recipient with diarrhea and abdominal pain. Recurring C. difficile infection.
Topics: Abdominal Pain; Adult; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Feces; G | 2001 |
Clinical quiz. An ileocolonic intussusception associated with C. difficile infection.
Topics: Abdominal Pain; Anti-Bacterial Agents; Clostridioides difficile; Diagnosis, Differential; Diarrhea; | 2001 |
[Clostridium difficile bacteremia].
Topics: Aged; Anti-Bacterial Agents; Antineoplastic Agents; Bacteremia; Clostridioides difficile; Enterocoli | 2001 |
Severe antibiotic-associated colitis in a patient with cystic fibrosis and colonic wall thickening.
Topics: Adult; Anti-Bacterial Agents; Clostridioides difficile; Colon; Cystic Fibrosis; Diagnosis, Different | 2002 |
[What measures are necessary in the demonstration of Clostridium difficile toxin?].
Topics: Adolescent; Aged; Anti-Bacterial Agents; Bacterial Toxins; Child; Clostridioides difficile; Enteroco | 2002 |
Necrotizing enterocolitis--an unconquered disease.
Topics: Anti-Infective Agents; Breast Feeding; Cefotaxime; Drug Therapy, Combination; Enterocolitis, Pseudom | 2002 |
In vitro activity of linezolid against Clostridium difficile.
Topics: Acetamides; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Drug Resistance, Bacterial; E | 2002 |
Reassessment of Clostridium difficile susceptibility to metronidazole and vancomycin.
Topics: Adult; Anti-Bacterial Agents; Clostridioides difficile; Drug Resistance, Microbial; Enterocolitis, P | 2002 |
Metronidazole for antibiotic-associated pseudomembraneous colitis.
Topics: Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Humans; Metronidazole | 1978 |
[Antibiotic-induced pseudomembranous Clostridium difficile colitis. A new etiopathogenetically definable infectious disease].
Topics: Anaerobiosis; Animals; Anti-Bacterial Agents; Bacterial Toxins; Clindamycin; Clostridium; Enterocoli | 1979 |
Metronidazole in the aetiology of pseudomembranous colitis.
Topics: Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Humans; Lincomycin; Metronidazole | 1979 |
[Treatment of pseudomembranous colitis with metronidazole].
Topics: Aged; Enterocolitis, Pseudomembranous; Humans; Male; Metronidazole | 1979 |
Pseudomembranous colitis in a colostomy.
Topics: Aged; Colostomy; Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole | 1978 |
Clindamycin-induced colitis.
Topics: Animals; Bacterial Toxins; Cecum; Clindamycin; Clostridium; Clostridium Infections; Cricetinae; Dise | 1979 |
Drug-induced colitis as a surgical disease.
Topics: Adrenal Cortex Hormones; Aged; Ampicillin; Atropine; Clindamycin; Colectomy; Colon; Diphenoxylate; E | 1976 |
Pseudomembranous colitis following resection for Hirschsprung's disease.
Topics: Administration, Rectal; Child, Preschool; Clostridioides difficile; Enterocolitis, Pseudomembranous; | 1992 |
[The diagnosis and treatment of Clostridium difficile enterocolitis].
Topics: Adult; Aged; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metron | 1991 |
Acute abdomen as the first presentation of pseudomembranous colitis.
Topics: Abdomen, Acute; Adult; Aged; Anti-Bacterial Agents; Colonoscopy; Diagnosis, Differential; Enterocoli | 1991 |
Control of Clostridium difficile colitis outbreak by treating asymptomatic carriers with metronidazole.
Topics: Aged; Carrier State; Disease Outbreaks; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metro | 1990 |
Pseudomembranous colitis: how useful is endoscopy?
Topics: Colonoscopy; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Sigm | 1990 |
Antibiotic-associated pseudomembranous colitis.
Topics: Administration, Oral; Costs and Cost Analysis; Enterocolitis, Pseudomembranous; Humans; Injections, | 1990 |
[Antibiotic associated diarrhea].
Topics: Anti-Bacterial Agents; Bacitracin; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Metronidazole; | 1990 |
[Pseudomembranous colitis caused by antibiotic therapy during aorto-iliac surgery].
Topics: Aorta, Abdominal; Blood Vessel Prosthesis; Cholestyramine Resin; Enterocolitis, Pseudomembranous; Hu | 1990 |
Failure of intravenous vancomycin and intravenous metronidazole to prevent or treat antibiotic-associated pseudomembranous colitis.
Topics: Enterocolitis, Pseudomembranous; Female; Humans; Injections, Intravenous; Male; Metronidazole; Middl | 1989 |
Cost-effective treatment of pseudomembranous colitis.
Topics: Cost-Benefit Analysis; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Prospective Studies; | 1989 |
Protein-losing enteropathy associated with Clostridium perfringens infection.
Topics: Child, Preschool; Clostridium perfringens; Enterocolitis, Pseudomembranous; Female; Humans; Metronid | 1989 |
Clostridium difficile in the intensive care unit: management problems and prevention issues.
Topics: Aged; Cross Infection; Enterocolitis, Pseudomembranous; Feces; Female; Humans; Intensive Care Units; | 1989 |
Treatment of Clostridium difficile diarrhea.
Topics: Diarrhea; Enterocolitis, Pseudomembranous; Humans; Metronidazole; Recurrence; Vancomycin | 1989 |
Treatment of Clostridium perfringens enterotoxin-associated diarrhoea with metronidazole.
Topics: Aged; Clostridium perfringens; Diarrhea; Enterocolitis, Pseudomembranous; Enterotoxins; Female; Huma | 1985 |
Failure of parenteral metronidazole in the treatment of pseudomembranous colitis.
Topics: Adult; Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole | 1988 |
Pseudomembranous colitis in association with Henoch Schonlein purpura.
Topics: Cephradine; Child; Drug Combinations; Enterocolitis, Pseudomembranous; Humans; IgA Vasculitis; Male; | 1988 |
Parenteral therapy for antibiotic-associated pseudomembranous colitis.
Topics: Aged; Enterocolitis, Pseudomembranous; Humans; Injections, Intravenous; Male; Metronidazole | 1988 |
Clostridium difficile colitis following treatment with metronidazole and vancomycin.
Topics: Adult; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole; Op | 1987 |
Treatment of relapsing Clostridium difficile diarrhoea by administration of a non-toxigenic strain.
Topics: Aged; Aged, 80 and over; Clostridium; Diarrhea; Enterocolitis, Pseudomembranous; Female; Humans; Met | 1987 |
[Long-standing pseudomembranous colitis ulcer after the use of intravaginal metronidazole].
Topics: Administration, Intravaginal; Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole; Middle | 1987 |
Pseudomembranous colitis: local experience with 3 cases.
Topics: Aged; Enterocolitis, Pseudomembranous; Female; Humans; Intestinal Mucosa; Male; Metronidazole; Middl | 1986 |
Localized pseudomembranous colitis simulating carcinoma of the cecum.
Topics: Aged; Carcinoma; Cecal Neoplasms; Colonoscopy; Diagnosis, Differential; Enterocolitis, Pseudomembran | 1987 |
Changing epidemiology, diagnosis, and treatment of Clostridium difficile toxin-associated colitis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacitracin; Bacterial Toxins; Child; Child, Preschoo | 1986 |
Faecal metronidazole concentrations during oral and intravenous therapy for antibiotic associated colitis due to Clostridium difficile.
Topics: Administration, Oral; Adult; Aged; Enterocolitis, Pseudomembranous; Feces; Female; Humans; Injection | 1986 |
Antibiotic-associated pseudomembranous colitis.
Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacitracin; Bacterial Proteins; Bacterial Toxins; Ce | 1985 |
Clostridium difficile colitis following head and neck surgery. Report of cases.
Topics: Aged; Anti-Bacterial Agents; Clostridium Infections; Diarrhea; Enterocolitis, Pseudomembranous; Head | 1985 |
Neonatal necrotizing enterocolitis: from reduction of mortality to reduction of morbidity.
Topics: Anesthesia, General; Combined Modality Therapy; Critical Care; Enterocolitis, Pseudomembranous; Huma | 1985 |
In vitro susceptibility of Clostridium difficile to new beta-lactam and quinolone antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Clindamycin; Clostridium; Diarrhea; Drug Resistance, Microbial; | 1985 |