metronidazole has been researched along with Enterobiasis in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Enterobiasis: Infection with nematodes of the genus ENTEROBIUS; E. vermicularis, the pinworm of man, causes a crawling sensation and pruritus. This condition results in scratching the area, occasionally causing scarification.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole treatment failure was significantly more frequent in patients with E." | 1.43 | Is the treatment of Enterobius vermicularis co-infection necessary to eradicate Dientamoeba fragilis infection? ( Boga, JA; Fernández, J; Iglesias, C; Martínez-Camblor, P; Rodríguez, M; Rodríguez-Guardado, A; Rojo, S; Vázquez, F, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boga, JA | 1 |
| Rojo, S | 1 |
| Fernández, J | 1 |
| Rodríguez, M | 1 |
| Iglesias, C | 1 |
| Martínez-Camblor, P | 1 |
| Vázquez, F | 1 |
| Rodríguez-Guardado, A | 1 |
| Olivares, JL | 1 |
| Fernández, R | 1 |
| Fleta, J | 1 |
| Rodríguez, G | 1 |
| Clavel, A | 1 |
2 other studies available for metronidazole and Enterobiasis
| Article | Year |
|---|---|
Is the treatment of Enterobius vermicularis co-infection necessary to eradicate Dientamoeba fragilis infection?
Topics: Adolescent; Adult; Aged; Animals; Anthelmintics; Antiprotozoal Agents; Child; Child, Preschool; Coin | 2016 |
Serum mineral levels in children with intestinal parasitic infection.
Topics: Adolescent; Antinematodal Agents; Antitrichomonal Agents; Child; Child, Preschool; Copper; Enterobia | 2003 |