Page last updated: 2024-10-31

metronidazole and Enteritis

metronidazole has been researched along with Enteritis in 18 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Enteritis: Inflammation of any segment of the SMALL INTESTINE.

Research Excerpts

ExcerptRelevanceReference
" The enteritis resolved quickly after initiation of combined oral vancomycin and metronidazole."8.84Treatment of metronidazole-refractory Clostridium difficile enteritis with vancomycin. ( Condron, SA; Follmar, KE; Ludwig, KA; Nathan, JD; Turner, II, 2008)
" A histological finding on the 15th day indicated the possibility of amoebic enteritis, and the patient was started on metronidazole therapy."3.81Fulminant amoebic enteritis that developed in the perinatal period. ( Goto, M; Matsuoka, T; Mizushima, Y, 2015)
"Pregnancy is a known risk factor for amebic enteritis, which develops into potentially fatal fulminant amebic enteritis in some cases."1.91Fulminant Amebic Enteritis in the Perinatal Period. ( Azuma, D; Inayama, Y; Kimura, H; Kunisaki, R; Maeda, K; Maeda, S; Nakamori, Y; Shibui, S; Tanabe, M; Toyoda, J; Watanabe, M; Yaguchi, K; Yukawa, T, 2023)
"Eosinophilic gastroenteritis is a rare inflammatory disorder of the gastrointestinal tract."1.62Eosinophilic gastroenteritis in an adolescent male with history of chronic bullous disease. ( Castor, MAR; Murillo, JML; Recto, MST; Tan-Lim, CSC, 2021)
"The clinical effect was evaluated by Crohn's Disease Activity Index (CDAI) and serum(s)-orosomucoid value."1.26Clinical effect of metronidazole and sulfasalazine on Crohn's disease in relation to changes in the fecal flora. ( Danielsson, D; Järnerot, G; Krook, A, 1981)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's2 (11.11)18.2507
2000's5 (27.78)29.6817
2010's3 (16.67)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Azuma, D1
Kunisaki, R1
Yukawa, T1
Yaguchi, K1
Watanabe, M1
Shibui, S1
Nakamori, Y1
Toyoda, J1
Tanabe, M1
Maeda, K1
Inayama, Y1
Kimura, H1
Maeda, S1
Heng, Y1
Hsu, CD1
Mathew, A1
Oh, PY1
Li, WT1
Xie, S1
Tan-Lim, CSC1
Murillo, JML1
Recto, MST1
Castor, MAR1
Okanishi, H1
Matsumoto, J1
Nogami, S1
Kagawa, Y1
Watari, T1
Goto, M1
Mizushima, Y1
Matsuoka, T1
Hariri, S1
Gouin, P1
Tuech, JJ1
Veber, B1
Dureuil, B1
Barr, BS1
Kim, KA1
Wry, P1
Hughes, E1
Butcher, J1
Barbot, D1
El Muhtaseb, MS1
Apollos, JK1
Dreyer, JS1
Romero Ganuza, FJ1
Follmar, KE1
Condron, SA1
Turner, II1
Nathan, JD1
Ludwig, KA1
Krook, A1
Järnerot, G1
Danielsson, D1
Brard, M1
de Longraye, J1
Yamada, T1
Deitch, E1
Specian, RD1
Perry, MA1
Sartor, RB1
Grisham, MB1
Donaldson, M1
Heyneman, D1
Dempster, R1
Garcia, L1
Libanore, M1
Bicocchi, R1
Rossi, MR1
Montanari, P1
Sighinolfi, L1
Macario, F1
Ghinelli, F1
García Pascual, L1
Bartolomé Comas, R1
Cuenca Luque, R1
San José Laporte, A1
Sharma, AK1
Shekhawat, NS1
Behari, S1
Chandra, S1
Sogani, KC1

Reviews

2 reviews available for metronidazole and Enteritis

ArticleYear
[Pancreatitis associated with metronidazole].
    Gastroenterologia y hepatologia, 2008, Volume: 31, Issue:4

    Topics: Abdominal Injuries; Acute Disease; Adult; Anti-Bacterial Agents; Cervical Vertebrae; Clostridium Inf

2008
Treatment of metronidazole-refractory Clostridium difficile enteritis with vancomycin.
    Surgical infections, 2008, Volume: 9, Issue:2

    Topics: Anti-Bacterial Agents; Clostridioides difficile; Drug Resistance, Multiple; Enteritis; Female; Human

2008

Other Studies

16 other studies available for metronidazole and Enteritis

ArticleYear
Fulminant Amebic Enteritis in the Perinatal Period.
    Internal medicine (Tokyo, Japan), 2023, Aug-15, Volume: 62, Issue:16

    Topics: Adult; Dysentery, Amebic; Enteritis; Female; Ganciclovir; Humans; Metronidazole; Pregnancy; Risk Fac

2023
MANAGEMENT OF
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2023, Volume: 54, Issue:2

    Topics: Amebiasis; Animals; Entamoeba; Enteritis; Metronidazole; Reptiles; Singapore

2023
Eosinophilic gastroenteritis in an adolescent male with history of chronic bullous disease.
    BMJ case reports, 2021, Feb-04, Volume: 14, Issue:2

    Topics: Abdominal Pain; Adolescent; Anti-Infective Agents; Appendicitis; Diarrhea; Enteritis; Eosinophilia;

2021
Echinostoma hortense infection with enteritis diagnosed by upper gastrointestinal endoscopy in a dog.
    The Journal of veterinary medical science, 2013, Jul-31, Volume: 75, Issue:7

    Topics: Animals; Dog Diseases; Dogs; Echinostoma; Echinostomiasis; Endoscopy, Gastrointestinal; Enteritis; F

2013
Fulminant amoebic enteritis that developed in the perinatal period.
    BMJ case reports, 2015, Jun-25, Volume: 2015

    Topics: Adult; Antiprotozoal Agents; Colon; Developed Countries; Dysentery, Amebic; Enteritis; Female; Human

2015
Clostridium difficile infection causing multiple organ failure and small-bowel enteritis.
    Clinics and research in hepatology and gastroenterology, 2011, Volume: 35, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Drug

2011
Infiltrative intestinal disease.
    The Veterinary clinics of North America. Equine practice, 2006, Volume: 22, Issue:1

    Topics: Abdomen; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Clioquinol; Dexamethasone; Diagno

2006
Clostridium difficile small-bowel enteritis after total proctocolectomy: a rare but fatal, easily missed diagnosis. Report of a case.
    Diseases of the colon and rectum, 2007, Volume: 50, Issue:6

    Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Enteritis; Enterocolitis, Pseudomembranous; F

2007
Clostridium difficile enteritis: a cause for high ileostomy output.
    ANZ journal of surgery, 2008, Volume: 78, Issue:5

    Topics: Anti-Infective Agents; Clostridioides difficile; Enteritis; Female; Humans; Ileostomy; Metronidazole

2008
Clinical effect of metronidazole and sulfasalazine on Crohn's disease in relation to changes in the fecal flora.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Bacteroides; Bacteroides Infections; Child; Colitis; Crohn Disease; Enteritis; Fe

1981
[Flagyl].
    Soins; la revue de reference infirmiere, 1981, Volume: 26, Issue:21

    Topics: Bacterial Infections; Enteritis; Humans; Intestinal Diseases, Parasitic; Metronidazole

1981
Mechanisms of acute and chronic intestinal inflammation induced by indomethacin.
    Inflammation, 1993, Volume: 17, Issue:6

    Topics: Acute Disease; Animals; Bacteria; Bile; Chronic Disease; Disease Models, Animal; Enteritis; Indometh

1993
Epizootic of fatal amebiasis among exhibited snakes: epidemiologic, pathologic, and chemotherapeutic considerations.
    American journal of veterinary research, 1975, Volume: 36, Issue:6

    Topics: Amebiasis; Animals; Animals, Zoo; Emetine; Entamoebiasis; Enteritis; Gastroenteritis; Inflammation;

1975
[Incidence of giardiasis in adults patients with acute enteritis].
    Minerva medica, 1991, Volume: 82, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Diarrhea; Enteritis; Fema

1991
[Enteritis caused by Blastocystis hominis].
    Medicina clinica, 1988, Dec-10, Volume: 91, Issue:20

    Topics: Adolescent; Animals; Enteritis; Eukaryota; Feces; Humans; Male; Metronidazole; Protozoan Infections

1988
Nonspecific jejunitis--a challenging problem in children.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Chloramphenicol; Diet; Enteritis; Epidemiologic Methods; Female

1986