metronidazole has been researched along with Enlarged Liver in 10 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole is an effective treatment and none of the patients required an invasive method for diagnosis or treatment." | 1.31 | Clinical characteristic of amoebic liver abscesses in the North of Iraq. ( Baban, FA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rehman Alvi, A | 1 |
| Rizvi, F | 1 |
| Kazim, SF | 1 |
| Ejaz, K | 1 |
| Zafar, H | 1 |
| Chawla, T | 1 |
| Bibi, S | 1 |
| Ur Rehman, Z | 1 |
| Ha, GY | 1 |
| Yang, CH | 1 |
| Kim, H | 1 |
| Chong, Y | 1 |
| Baban, FA | 1 |
| Weinke, T | 1 |
| Grobusch, MP | 1 |
| Güthoff, W | 1 |
| Archampong, EQ | 1 |
| Lichtman, SN | 1 |
| Keku, J | 1 |
| Schwab, JH | 1 |
| Sartor, RB | 1 |
| Antani, J | 1 |
| Srinivas, HV | 1 |
| Steinitz, H | 1 |
| Powell, SJ | 1 |
| Stewart-Wynne, EJ | 1 |
| Elsdon-Dew, R | 1 |
| Lapierre, J | 1 |
10 other studies available for metronidazole and Enlarged Liver
| Article | Year |
|---|---|
Amoebic liver abscess: experience in a south Asian country.
Topics: Abdominal Pain; Animals; Anti-Infective Agents; Combined Modality Therapy; Female; Fever; Hepatomega | 2010 |
Case of sepsis caused by Bifidobacterium longum.
Topics: Actinomycetales Infections; Acupuncture Analgesia; Adult; Anti-Bacterial Agents; Bifidobacterium; Fe | 1999 |
Clinical characteristic of amoebic liver abscesses in the North of Iraq.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Diagnosis, Differential; Fever; Hepatomegaly; Humans | 2000 |
Amebic liver abscess--rare need for percutaneous treatment modalities.
Topics: Abdominal Pain; Adult; Anti-Infective Agents; Biopsy, Needle; Female; Fever; Germany; Hepatomegaly; | 2002 |
Amoebic liver disease.
Topics: Adolescent; Adult; Carcinoma, Hepatocellular; Child; Diagnosis, Differential; Female; Hepatomegaly; | 1977 |
Hepatic injury associated with small bowel bacterial overgrowth in rats is prevented by metronidazole and tetracycline.
Topics: Animals; Bacteria; Bacterial Infections; Colony Count, Microbial; Female; Gentamicins; Hepatomegaly; | 1991 |
Clinical evaluation of metronidazole in hepatic amebiasis.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Cecum; Colon; Dysent | 1970 |
The treatment of chronic amoebic infection with metronidazole (flagyl).
Topics: Adult; Amebiasis; Chronic Disease; Dientamoeba; Dysentery, Amebic; Entamoeba histolytica; Feces; Fem | 1972 |
Metronidazole combined with diloxanide furoate in amoebic liver abscess.
Topics: Acetanilides; Adult; Amebicides; Dysentery, Amebic; Emetine; Entamoeba histolytica; Fever; Furans; H | 1973 |
[Leishmaniasis].
Topics: Amidines; Amphotericin B; Anemia; Animals; Antimony; Blood Protein Electrophoresis; Child, Preschool | 1969 |