metronidazole has been researched along with Empyema, Pleural in 10 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Empyema, Pleural: Suppurative inflammation of the pleural space.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of treatment of pyothorax using systemic antibiotics, drainage, and lavage of the pleural space, are reported for 9 dogs." | 1.31 | Pyothorax in nine dogs. ( Piek, CJ; Robben, JH, 2000) |
| "Treatment with metronidazole successfully eliminated the protozoa and cured the pyothorax." | 1.30 | Trichomonas tenax empyema in an immunocompromised patient with advanced cancer. ( Arizono, N; Morimoto, T; Nakao, K; Shimatsu, A; Shiota, T, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, N | 1 |
| Jin, X | 1 |
| Huang, J | 1 |
| Chen, K | 1 |
| Li, Y | 1 |
| Chen, C | 1 |
| Hu, D | 1 |
| Xie, Y | 1 |
| Loulergue, P | 1 |
| Mir, O | 1 |
| Chang, HR | 1 |
| Lee, JJ | 1 |
| Lin, CB | 1 |
| Calvert, LD | 1 |
| Collins, M | 1 |
| Bateman, JR | 1 |
| Johnson, MS | 1 |
| Martin, MW | 1 |
| Turner, P | 1 |
| Edwards, R | 1 |
| Weston, V | 1 |
| Gazis, A | 1 |
| Ispahani, P | 1 |
| Greenwood, D | 1 |
| Radosavljevic-Asic, G | 1 |
| Jovanovic, D | 1 |
| Radovanovic, D | 1 |
| Tucakovic, M | 1 |
| Shiota, T | 1 |
| Arizono, N | 1 |
| Morimoto, T | 1 |
| Shimatsu, A | 1 |
| Nakao, K | 1 |
| Piek, CJ | 1 |
| Robben, JH | 1 |
| Teixeira, LR | 1 |
| Sasse, SA | 1 |
| Villarino, MA | 1 |
| Nguyen, T | 1 |
| Mulligan, ME | 1 |
| Light, RW | 1 |
10 other studies available for metronidazole and Empyema, Pleural
| Article | Year |
|---|---|
Tetratrichomonas in pyopneumothorax.
Topics: Aged, 80 and over; Antiprotozoal Agents; Cilastatin; Empyema, Pleural; Female; Humans; Imipenem; Met | 2019 |
Pleural empyema secondary to amebic liver abscess.
Topics: Amebicides; Animals; Biopsy, Needle; Empyema, Pleural; Entamoeba histolytica; Humans; Liver Abscess, | 2009 |
Pleural empyema secondary to rupture of amoebic liver abscess.
Topics: Adult; Amebicides; Drainage; Empyema, Pleural; Follow-Up Studies; Humans; Iodoquinol; Liver Abscess, | 2012 |
Multiple abscesses caused by Gardnerella vaginalis in an immunocompetent man.
Topics: Abdominal Abscess; Bacterial Infections; Cefuroxime; Empyema, Pleural; Gardnerella vaginalis; Humans | 2005 |
Successful medical treatment of 15 dogs with pyothorax.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Dog Diseases; Dogs; Drainage; Empyema, Pleural; Female; | 2007 |
Simultaneous resistance to metronidazole, co-amoxiclav, and imipenem in clinical isolate of Bacteroides fragilis.
Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bacteremia; Bacteroides fragilis; | 1995 |
Trichomonas in pleural effusion.
Topics: Adult; Bacterial Infections; Empyema, Pleural; Humans; Lung Diseases, Parasitic; Male; Metronidazole | 1994 |
Trichomonas tenax empyema in an immunocompromised patient with advanced cancer.
Topics: Acromegaly; Adenocarcinoma; Animals; Antitrichomonal Agents; Bone Marrow Neoplasms; Brain Neoplasms; | 1998 |
Pyothorax in nine dogs.
Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Infective Agents; Dog Diseases; Dogs; D | 2000 |
Antibiotic levels in empyemic pleural fluid.
Topics: Animals; Anti-Bacterial Agents; Biological Availability; Ceftriaxone; Clindamycin; Disease Models, A | 2000 |