Page last updated: 2024-10-31

metronidazole and Emphysema

metronidazole has been researched along with Emphysema in 10 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Emphysema: A pathological accumulation of air in tissues or organs.

Research Excerpts

ExcerptRelevanceReference
"Emphysematous gastritis is a life-threatening disease."2.42Emphysematous gastritis and severe aplastic anemia. ( Cantalapiedra, A; Del Villar, R; García-Frade, LJ; Gutierrez, O; Peñarrubia, MJ; Sales, R; Tabuyo, MI, 2003)
"Emphysematous gastritis is a rare disease caused by gas-forming organisms."1.51Recognizing emphysematous gastritis. ( Smith, B; Weaver, A; Weintraub, R, 2019)
"Hence the diagnosis of pseudomembranous colitis became apparent."1.40Emphysematous cystitis due to recurrent Clostridium difficile infection. ( Dees, A; Jonkman, JG; van Genderen, ME; van Rijn, M, 2014)
"Emphysematous gastritis is a rare form of gastritis characterized by gaseous dissection of the stomach wall usually secondary to invasion by gas forming organisms, corrosive ingestion, trauma, or gastric infarction."1.37Emphysematous gastritis associated with ulcerative esophagitis. ( Abbass, K; Akram, S; Hassan, S; Markert, R, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's7 (70.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weaver, A1
Weintraub, R1
Smith, B1
van Genderen, ME1
Jonkman, JG1
van Rijn, M1
Dees, A1
Al Rasheed, MR1
Senseng, CG1
Ayoub, T1
Arshad, I1
Donnellan, I1
Gupta, P1
Gupta, R2
Jandial, K1
Samotra, S1
Rana, V1
Gupta, S1
Singh, J1
Hassan, S1
Abbass, K1
Markert, R1
Akram, S1
Kim, JH2
Jung, ES1
Jeong, SH1
Kim, JS1
Ku, YS1
Hahm, KB1
Kim, YS1
Knežević, M1
Rašić, D1
Stojković, M1
Jovanović, M1
Božić, M1
Gutierrez, O1
Cantalapiedra, A1
Tabuyo, MI1
Del Villar, R1
Peñarrubia, MJ1
Sales, R1
García-Frade, LJ1
Jensen, SL1
Amato, JE1
Hartstein, ME1
Breer, WA1

Reviews

3 reviews available for metronidazole and Emphysema

ArticleYear
Sarcina ventriculi : Review of the Literature.
    Archives of pathology & laboratory medicine, 2016, Volume: 140, Issue:12

    Topics: Anti-Infective Agents; Clostridium Infections; Diagnosis, Differential; Drug Therapy, Combination; E

2016
Acute post-surgical bilateral orbital gas-producing infection - a case report and literature review.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2012, Volume: 250, Issue:9

    Topics: Acute Disease; Anti-Bacterial Agents; Drug Therapy, Combination; Emphysema; Eye Infections, Bacteria

2012
Emphysematous gastritis and severe aplastic anemia.
    The hematology journal : the official journal of the European Haematology Association, 2003, Volume: 4, Issue:1

    Topics: Anemia, Aplastic; Antilymphocyte Serum; Cholelithiasis; Cyclosporine; Emphysema; Female; Gastritis;

2003

Other Studies

7 other studies available for metronidazole and Emphysema

ArticleYear
Recognizing emphysematous gastritis.
    JAAPA : official journal of the American Academy of Physician Assistants, 2019, Volume: 32, Issue:2

    Topics: Administration, Intravenous; Aged; Emphysema; Gastritis; Humans; Levofloxacin; Male; Metronidazole;

2019
Emphysematous cystitis due to recurrent Clostridium difficile infection.
    BMJ case reports, 2014, Dec-17, Volume: 2014

    Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Cystitis; Emphysema;

2014
Concurrent emphysematous cholecystitis and emphysematous cystitis in a non-diabetic patient.
    British journal of hospital medicine (London, England : 2005), 2009, Volume: 70, Issue:10

    Topics: Aged, 80 and over; Anti-Infective Agents; Cefuroxime; Cystitis; Drug Therapy, Combination; Emphysema

2009
Emphysematous pyelonephritis in the setting of diabetes mellitus.
    The Journal of the Association of Physicians of India, 2011, Volume: 59

    Topics: Anti-Infective Agents; Diabetes Mellitus, Type 2; Diagnosis, Differential; Emphysema; Escherichia co

2011
Emphysematous gastritis associated with ulcerative esophagitis.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:11

    Topics: Aged; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Diabetes Mellitus, Type 2; Emphyse

2011
A case of emphysematous hepatitis with spontaneous pneumoperitoneum in a patient with hilar cholangiocarcinoma.
    The Korean journal of hepatology, 2012, Volume: 18, Issue:1

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cefotaxime;

2012
Bilateral periorbital necrotizing fasciitis.
    Archives of dermatology, 2004, Volume: 140, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Arthritis, Rheumatoid; Bacteremia; Bronchopneumonia; Ceftriaxone; Debri

2004