metronidazole has been researched along with Embolism, Pulmonary in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report an unusual presentation of pulmonary embolism (PE) where a 58-year-old man first developed symptoms of community-acquired pneumonia." | 1.48 | An unusual presentation of pulmonary embolism leading to infarction, cavitation, abscess formation and bronchopleural fistulation. ( Banerjee, A; Bennett, L; Morelli, T; Teng, E, 2018) |
| "Lemierre's syndrome is a rare disease in young otherwise healthy people showing septic embolism in the lungs and peripheral vessels." | 1.36 | [Phlegmon of the palm of the hand as initial manifestation of the Lemierre syndrome]. ( Braunbeck, A; Daecke, W; Fiebig, C; Geiger, EV; Maier, M; Marzi, I; Weber, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teng, E | 1 |
| Bennett, L | 1 |
| Morelli, T | 1 |
| Banerjee, A | 1 |
| Thati, V | 1 |
| Nagral, S | 1 |
| Braunbeck, A | 1 |
| Geiger, EV | 1 |
| Weber, R | 1 |
| Maier, M | 1 |
| Daecke, W | 1 |
| Fiebig, C | 1 |
| Marzi, I | 1 |
3 other studies available for metronidazole and Embolism, Pulmonary
| Article | Year |
|---|---|
An unusual presentation of pulmonary embolism leading to infarction, cavitation, abscess formation and bronchopleural fistulation.
Topics: Abscess; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bronchial Fistula; Di | 2018 |
Inferior vena cava thrombus with pulmonary embolism complicating amebic liver abscess.
Topics: Heparin, Low-Molecular-Weight; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; Pulm | 2014 |
[Phlegmon of the palm of the hand as initial manifestation of the Lemierre syndrome].
Topics: Abscess; Acromioclavicular Joint; Anti-Bacterial Agents; Cellulitis; Combined Modality Therapy; Diag | 2010 |