metronidazole has been researched along with Electrolytes in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
Excerpt | Relevance | Reference |
---|---|---|
"Metronidazole and neomycin were used for antibiotic coverage." | 1.27 | Use of a balanced bowel preparation solution in urological surgery. ( Clark, WR; Furlow, WL, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (40.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
De Lima, MS | 1 |
Freire, MS | 1 |
Fonseca, JL | 1 |
Pereira, MR | 1 |
Bowie, MD | 1 |
Mann, MD | 1 |
Hill, ID | 1 |
Samour, JH | 1 |
Bailey, TA | 1 |
Cooper, JE | 1 |
Frazee, RC | 1 |
Roberts, J | 1 |
Symmonds, R | 1 |
Snyder, S | 1 |
Hendricks, J | 1 |
Smith, R | 1 |
Clark, WR | 1 |
Furlow, WL | 1 |
1 trial available for metronidazole and Electrolytes
Article | Year |
---|---|
Prospective, randomized trial of inpatient vs. outpatient bowel preparation for elective colorectal surgery.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Colon; Diet; Electrolytes; Female; Hospitalization; | 1992 |
4 other studies available for metronidazole and Electrolytes
Article | Year |
---|---|
Chitosan membranes modified by contact with poly(acrylic acid).
Topics: Absorption; Acrylic Resins; Chitosan; Electrolytes; Membranes, Artificial; Metronidazole; Microscopy | 2009 |
The bowel cocktail.
Topics: Cholestyramine Resin; Diarrhea; Electrolytes; Fluid Therapy; Gastroenteritis; Gentamicins; Glucose; | 1981 |
Trichomoniasis in birds of prey (order Falconiformes) in Bahrain.
Topics: Air Sacs; Animals; Bahrain; Bird Diseases; Birds; Crop, Avian; Dimetridazole; Electrolytes; Esophage | 1995 |
Use of a balanced bowel preparation solution in urological surgery.
Topics: Electrolytes; Female; Humans; Male; Metronidazole; Middle Aged; Neomycin; Polyethylene Glycols; Prem | 1987 |