Page last updated: 2024-10-31

metronidazole and Dysphagia

metronidazole has been researched along with Dysphagia in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"She quickly developed dysphagia and odynophagia with subsequent generalised spasms and profound hypoxic respiratory failure requiring nasotracheal intubation."1.51Return of the old guard: a case of tetanus in an unvaccinated patient. ( Gega, A; Ibe, U; Jiwa, N; Rehmani, S, 2019)
"Necrotizing stomatitis is more commonly encountered in malnourished children in developing countries, and may subsequently result in devastating facial defects and death."1.33Necrotizing stomatitis in the developed world. ( Buchanan, JA; Cedro, M; Hodgson, TA; Joseph, T; Mirdin, A; Porter, SR, 2006)
"Amoxicillin was the most frequently prescribed antibiotic."1.32Pattern of antibiotic prescription in the management of oral diseases among dentists in Kuwait. ( Adib, SM; Al-Mutawa, S; Rotimi, VO; Salako, NO, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ibe, U1
Rehmani, S1
Jiwa, N1
Gega, A1
Salako, NO1
Rotimi, VO1
Adib, SM1
Al-Mutawa, S1
Buchanan, JA1
Cedro, M1
Mirdin, A1
Joseph, T1
Porter, SR1
Hodgson, TA1

Other Studies

3 other studies available for metronidazole and Dysphagia

ArticleYear
Return of the old guard: a case of tetanus in an unvaccinated patient.
    BMJ case reports, 2019, Jun-26, Volume: 12, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Deglutition Disorders; Female; Gastrostomy; Humans; Metronidazole; Resp

2019
Pattern of antibiotic prescription in the management of oral diseases among dentists in Kuwait.
    Journal of dentistry, 2004, Volume: 32, Issue:7

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Clinical Com

2004
Necrotizing stomatitis in the developed world.
    Clinical and experimental dermatology, 2006, Volume: 31, Issue:3

    Topics: Aged; Analgesics; Debridement; Deglutition Disorders; Developed Countries; Dietary Supplements; Ging

2006