Page last updated: 2024-10-31

metronidazole and Dyslipidemia

metronidazole has been researched along with Dyslipidemia in 1 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"A 61-year-old man with chronic hepatitis B and dyslipidemia visited the emergency department with a fever and severe headache."1.42Bacteremic meningitis caused by Parvimonas micra in an immunocompetent host. ( Baek, JY; Cho, SY; Chung, DR; Ha, YE; Kang, CI; Kim, SH; Ko, JH; Lee, JY; Lee, NY; Lee, WJ; Peck, KR; Song, JH, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ko, JH1
Baek, JY1
Kang, CI1
Lee, WJ1
Lee, JY1
Cho, SY1
Ha, YE1
Kim, SH1
Chung, DR1
Peck, KR1
Lee, NY1
Song, JH1

Other Studies

1 other study available for metronidazole and Dyslipidemia

ArticleYear
Bacteremic meningitis caused by Parvimonas micra in an immunocompetent host.
    Anaerobe, 2015, Volume: 34

    Topics: Anti-Bacterial Agents; Bacteremia; Bacteria, Anaerobic; Ceftriaxone; Dyslipidemias; Firmicutes; Gram

2015