metronidazole has been researched along with Dysentery in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Dysentery: Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION.
Excerpt | Relevance | Reference |
---|---|---|
"In 1977 swine dysentery was made a notifiable disease in the German Democratic Republic, with the intention of eradicating it by the systematic treatment of clinically affected herds using intensive medication and hygiene control programmes." | 5.27 | Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. ( Blaha, T; Burch, DG; Erler, W, 1987) |
"Giardiasis is one of the most common causes of diarrheal disease worldwide." | 1.39 | A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia. ( Debnath, A; Eckmann, L; Gut, J; Leitsch, D; McKerrow, JH; Miyamoto, Y; Reed, SL; Santini, J; Tejman-Yarden, N, 2013) |
"In 1977 swine dysentery was made a notifiable disease in the German Democratic Republic, with the intention of eradicating it by the systematic treatment of clinically affected herds using intensive medication and hygiene control programmes." | 1.27 | Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. ( Blaha, T; Burch, DG; Erler, W, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (57.14) | 18.7374 |
1990's | 2 (28.57) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Tejman-Yarden, N | 1 |
Miyamoto, Y | 1 |
Leitsch, D | 1 |
Santini, J | 1 |
Debnath, A | 1 |
Gut, J | 1 |
McKerrow, JH | 1 |
Reed, SL | 1 |
Eckmann, L | 1 |
Bhutta, TI | 1 |
Vitry, A | 1 |
Alam, MB | 1 |
Ahmed, FU | 1 |
Rahman, ME | 1 |
Dellamonica, P | 1 |
Le Fichoux, Y | 1 |
Monnier, B | 1 |
Duplay, H | 1 |
Blaha, T | 1 |
Erler, W | 1 |
Burch, DG | 1 |
Schulze, F | 1 |
Kielstein, P | 1 |
Rey, M | 1 |
Lafaix, C | 1 |
Mar, ID | 1 |
Charmot, G | 1 |
7 other studies available for metronidazole and Dysentery
Article | Year |
---|---|
A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia.
Topics: Animals; Anti-Infective Agents; Antirheumatic Agents; Auranofin; Drug Repositioning; Drug Resistance | 2013 |
Treating dysentery with metronidazole in Pakistan.
Topics: Child; Child, Preschool; Dysentery; Humans; Metronidazole | 1997 |
Misuse of drugs in acute diarrhoea in under-five children.
Topics: Acute Disease; Analysis of Variance; Anti-Bacterial Agents; Anti-Infective Agents; Antidiarrheals; B | 1998 |
[Dysenteric syndrome and urticaria in giardiasis].
Topics: Adult; Dysentery; Female; Giardiasis; Humans; Metronidazole; Urticaria | 1976 |
Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme.
Topics: Animals; Anti-Bacterial Agents; Diterpenes; Dysentery; Female; Follow-Up Studies; Germany, East; Leu | 1987 |
[Effect of metronidazole on the gastrointestinal flora of swine].
Topics: Animals; Bacteria; Digestive System; Dysentery; Metronidazole; Swine; Swine Diseases | 1987 |
[A major new ambeicide: metronidazole].
Topics: Adolescent; Adult; Child; Child, Preschool; Colitis; Diarrhea; Dysentery; Hepatitis; Humans; Infant; | 1969 |