Page last updated: 2024-10-31

metronidazole and Dysentery

metronidazole has been researched along with Dysentery in 7 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Dysentery: Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION.

Research Excerpts

ExcerptRelevanceReference
"In 1977 swine dysentery was made a notifiable disease in the German Democratic Republic, with the intention of eradicating it by the systematic treatment of clinically affected herds using intensive medication and hygiene control programmes."5.27Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. ( Blaha, T; Burch, DG; Erler, W, 1987)
"Giardiasis is one of the most common causes of diarrheal disease worldwide."1.39A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia. ( Debnath, A; Eckmann, L; Gut, J; Leitsch, D; McKerrow, JH; Miyamoto, Y; Reed, SL; Santini, J; Tejman-Yarden, N, 2013)
"In 1977 swine dysentery was made a notifiable disease in the German Democratic Republic, with the intention of eradicating it by the systematic treatment of clinically affected herds using intensive medication and hygiene control programmes."1.27Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. ( Blaha, T; Burch, DG; Erler, W, 1987)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tejman-Yarden, N1
Miyamoto, Y1
Leitsch, D1
Santini, J1
Debnath, A1
Gut, J1
McKerrow, JH1
Reed, SL1
Eckmann, L1
Bhutta, TI1
Vitry, A1
Alam, MB1
Ahmed, FU1
Rahman, ME1
Dellamonica, P1
Le Fichoux, Y1
Monnier, B1
Duplay, H1
Blaha, T1
Erler, W1
Burch, DG1
Schulze, F1
Kielstein, P1
Rey, M1
Lafaix, C1
Mar, ID1
Charmot, G1

Other Studies

7 other studies available for metronidazole and Dysentery

ArticleYear
A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:5

    Topics: Animals; Anti-Infective Agents; Antirheumatic Agents; Auranofin; Drug Repositioning; Drug Resistance

2013
Treating dysentery with metronidazole in Pakistan.
    BMJ (Clinical research ed.), 1997, Jan-11, Volume: 314, Issue:7074

    Topics: Child; Child, Preschool; Dysentery; Humans; Metronidazole

1997
Misuse of drugs in acute diarrhoea in under-five children.
    Bangladesh Medical Research Council bulletin, 1998, Volume: 24, Issue:2

    Topics: Acute Disease; Analysis of Variance; Anti-Bacterial Agents; Anti-Infective Agents; Antidiarrheals; B

1998
[Dysenteric syndrome and urticaria in giardiasis].
    La Nouvelle presse medicale, 1976, Sep-18, Volume: 5, Issue:30

    Topics: Adult; Dysentery; Female; Giardiasis; Humans; Metronidazole; Urticaria

1976
Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme.
    The Veterinary record, 1987, Oct-31, Volume: 121, Issue:18

    Topics: Animals; Anti-Bacterial Agents; Diterpenes; Dysentery; Female; Follow-Up Studies; Germany, East; Leu

1987
[Effect of metronidazole on the gastrointestinal flora of swine].
    Die Nahrung, 1987, Volume: 31, Issue:5-6

    Topics: Animals; Bacteria; Digestive System; Dysentery; Metronidazole; Swine; Swine Diseases

1987
[A major new ambeicide: metronidazole].
    Bulletin de la Societe medicale d'Afrique noire de langue francaise, 1969, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Colitis; Diarrhea; Dysentery; Hepatitis; Humans; Infant;

1969