metronidazole has been researched along with Dysarthosis in 13 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acute reversible cerebellar ataxia with confusion secondary to prolonged metronidazole use has been reported rarely as a cause of encephalopathy in patients with ALD." | 3.83 | Metronidazole-Induced Encephalopathy in Alcoholic Liver Disease: A Diagnostic and Therapeutic Challenge. ( Contractor, Q; Jain, SS; Mohite, AR; Pawar, SV; Rathi, PM; Sonthalia, N; Surude, RG, 2016) |
| "We infer that the progression of encephalopathy is related to the delayed toxicity caused by high dose or concentration of metronidazole." | 1.51 | A case of methylprednisolone treatment for metronidazole-induced encephalopathy. ( Li, L; Li, W; Liang, S; Tang, X; Wu, M; Zhu, Q, 2019) |
| "Encefalopathy as a side effect of metronidazole therapy - a case report Neurological symptoms as side effects of pharmacological treatment generally tend to remain underdiagnosed." | 1.46 | [Encefalopathy as a side effect of metronidazole therapy – a case report]. ( Karayianni, M; Laska, AC; von Heijne, A, 2017) |
| "Cerebral actinomycosis is rare and difficult to diagnose." | 1.37 | [Cerebral actinomycosis pseudotumor: a case report]. ( Battikh, R; Ben Abdelhafidh, N; Bougrine, F; Bouziani, A; M'Sadek, F; Madhi, W; Othmani, S; Yedeas, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Miki, Y | 2 |
| Takeuchi, Y | 2 |
| Murasawa, S | 2 |
| Takayasu, S | 2 |
| Tsushima, F | 2 |
| Kakeda, S | 2 |
| Mizukami, H | 2 |
| Wakabayashi, K | 2 |
| John, KJ | 1 |
| P Pillai, D | 1 |
| Pillai, V | 1 |
| John, JK | 1 |
| Karayianni, M | 1 |
| von Heijne, A | 1 |
| Laska, AC | 1 |
| Yui, JC | 1 |
| Bonnes, SL | 1 |
| Li, L | 1 |
| Tang, X | 1 |
| Li, W | 1 |
| Liang, S | 1 |
| Zhu, Q | 1 |
| Wu, M | 1 |
| Vivas, LLY | 1 |
| Gold, WL | 1 |
| Mandell, DM | 1 |
| Wu, PE | 1 |
| Briongos-Figuero, LS | 1 |
| Bachiller-Luque, P | 1 |
| Pastor-Mancisidor, L | 1 |
| Carreres-Rodríguez, A | 1 |
| Mena-Martín, FJ | 1 |
| Farmakiotis, D | 1 |
| Zeluff, B | 1 |
| Sonthalia, N | 1 |
| Pawar, SV | 1 |
| Mohite, AR | 1 |
| Jain, SS | 1 |
| Surude, RG | 1 |
| Rathi, PM | 1 |
| Contractor, Q | 1 |
| Kuriyama, A | 1 |
| Battikh, R | 1 |
| M'Sadek, F | 1 |
| Bougrine, F | 1 |
| Madhi, W | 1 |
| Ben Abdelhafidh, N | 1 |
| Bouziani, A | 1 |
| Yedeas, M | 1 |
| Othmani, S | 1 |
| Heaney, CJ | 1 |
| Campeau, NG | 1 |
| Lindell, EP | 1 |
| Woodruff, BK | 1 |
| Wijdicks, EF | 1 |
| Marshall, WF | 1 |
13 other studies available for metronidazole and Dysarthosis
| Article | Year |
|---|---|
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic | 2022 |
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic | 2022 |
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic | 2022 |
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic | 2022 |
Metronidazole-induced reversible cerebellar dysfunction.
Topics: Aged; Anti-Bacterial Agents; Ataxia; Cerebellar Diseases; Cerebellar Nuclei; Duration of Therapy; Dy | 2021 |
[Encefalopathy as a side effect of metronidazole therapy – a case report].
Topics: Abscess; Aged; Anti-Infective Agents; Ataxia; Brain Diseases; Dysarthria; Female; Gait Disorders, Ne | 2017 |
74-Year-Old Woman With Dysarthria and Left Lower Extremity Weakness.
Topics: Aged; Anti-Infective Agents; Dysarthria; Female; Humans; Lower Extremity; Metronidazole; Muscle Weak | 2017 |
A case of methylprednisolone treatment for metronidazole-induced encephalopathy.
Topics: Brain Diseases; Dysarthria; Gait Ataxia; Humans; Magnetic Resonance Imaging; Male; Methylprednisolon | 2019 |
An 82-year-old man with ataxia and dysarthria.
Topics: Aged, 80 and over; Anti-Infective Agents; Ataxia; Brain; Cerebellar Nuclei; Diabetes Mellitus, Type | 2016 |
[Cerebellar syndrome induced by metronidazole: a rare side effect].
Topics: Anti-Bacterial Agents; Brain Abscess; Cefotaxime; Cephalosporins; Cerebellar Ataxia; Diagnosis, Diff | 2016 |
IMAGES IN CLINICAL MEDICINE. Metronidazole-Associated Encephalopathy.
Topics: Bacteremia; Brain Diseases; Catheterization, Central Venous; Clostridium Infections; Dysarthria; Fat | 2016 |
Metronidazole-Induced Encephalopathy in Alcoholic Liver Disease: A Diagnostic and Therapeutic Challenge.
Topics: Anti-Infective Agents; Cerebellar Ataxia; Confusion; Dysarthria; Humans; Liver Diseases, Alcoholic; | 2016 |
Chestnut Sign: Metronidazole-Induced Encephalopathy.
Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Ataxia; Brain Diseases; Ciprofloxacin; Depression; D | 2017 |
[Cerebral actinomycosis pseudotumor: a case report].
Topics: Actinomycosis; Adrenal Cortex Hormones; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacteria | 2011 |
MR imaging and diffusion-weighted imaging changes in metronidazole (Flagyl)-induced cerebellar toxicity.
Topics: Abdominal Abscess; Abdominal Neoplasms; Aged; Amoxicillin; Anti-Infective Agents; Carcinoid Tumor; C | 2003 |
Reversible metronidazole-induced lesions of the cerebellar dentate nuclei.
Topics: Aged; Anti-Infective Agents; Ataxia; Cerebellar Nuclei; Dysarthria; Humans; Magnetic Resonance Imagi | 2002 |