metronidazole has been researched along with Duodenal Diseases in 10 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Duodenal Diseases: Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole resistance was found in 6." | 1.30 | Helicobacter pylori in gastric biopsies of Taiwanese patients with gastroduodenal diseases. ( Chang, YS; Cheng, KS; Lin, CW; Wu, SC, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feagins, LA | 1 |
| Chan, V | 1 |
| Spechler, SJ | 1 |
| Ugajin, T | 1 |
| Miyatani, H | 1 |
| Matsumoto, S | 1 |
| Takamatsu, T | 1 |
| Fukunishi, M | 1 |
| Yoshida, Y | 1 |
| Dobashi, Y | 1 |
| FULPIUS, B | 1 |
| HAUSSER, E | 1 |
| ROSNER, P | 1 |
| Descloux, A | 1 |
| Wiens, M | 1 |
| Pérez-Roldán, F | 1 |
| Mate-Valdezate, A | 1 |
| Villafáñez-García, MC | 1 |
| González Carro, P | 1 |
| Legaz Huidobro, ML | 1 |
| Orth, T | 1 |
| Protzer, U | 1 |
| Mayet, WJ | 1 |
| Meyer zum Büschenfelde, KH | 1 |
| Banatvala, N | 1 |
| Davies, GR | 1 |
| Abdi, Y | 1 |
| Clements, L | 1 |
| Rampton, DS | 1 |
| Hardie, JM | 1 |
| Feldman, RA | 1 |
| Lin, CW | 1 |
| Chang, YS | 1 |
| Wu, SC | 1 |
| Cheng, KS | 1 |
| Chan, KL | 1 |
| Zhou, H | 1 |
| Ng, DK | 1 |
| Tam, PK | 1 |
| Besselink, MG | 1 |
| Berende, NC | 1 |
| Preshaw, RM | 1 |
| Romano, C | 1 |
| Kortbeek, J | 1 |
10 other studies available for metronidazole and Duodenal Diseases
| Article | Year |
|---|---|
A case of duodenal Entamoeba histolytica.
Topics: Adult; AIDS-Related Opportunistic Infections; Amebicides; Animals; Biopsy; Drug Administration Sched | 2009 |
Regression of multiple duodenal hyperplastic polyps following Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biop | 2011 |
[MEGALOBLASTIC ANEMIA AND INTESTINAL DIVERTICULOSIS].
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Diverticulum; Drug Therapy; Duodenal Diseases; Humans; In | 1965 |
[Paraduodenal hernia: case report of an operative accidental diagnosis].
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Diverticulitis, Colonic; Duodenal D | 2007 |
Nodular lymphoid hyperplasia by Giardia lamblia.
Topics: Animals; Antigens, Protozoan; Biopsy, Needle; Duodenal Diseases; Duodenoscopy; Female; Follow-Up Stu | 2008 |
[Long-term damage to duodenal mucosa in malabsorption syndrome as a sequela of Giardia lamblia infection].
Topics: Adult; Animals; Antiprotozoal Agents; Atrophy; Dose-Response Relationship, Drug; Drug Administration | 1995 |
High prevalence of Helicobacter pylori metronidazole resistance in migrants to east London: relation with previous nitroimidazole exposure and gastroduodenal disease.
Topics: Adult; Developing Countries; Drug Resistance, Microbial; Duodenal Diseases; Female; Helicobacter Inf | 1994 |
Helicobacter pylori in gastric biopsies of Taiwanese patients with gastroduodenal diseases.
Topics: ABO Blood-Group System; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigens, Bacterial; | 1998 |
A prospective study of a one-week nonbismuth quadruple therapy for childhood Helicobacter pylori infection.
Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Child; Child, Preschool; C | 2001 |
Non-operative treatment of duodenal perforation secondary to blunt abdominal trauma.
Topics: Adolescent; Ampicillin; Anti-Infective Agents; Duodenal Diseases; Enteral Nutrition; Female; Fluid T | 2001 |