metronidazole has been researched along with Dizziness in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Dizziness: An imprecise term which may refer to a sense of spatial disorientation, motion of the environment, or lightheadedness.
Excerpt | Relevance | Reference |
---|---|---|
" Mostly, metronidazole is a tolerable drug but rarely presents serious adverse effects on the nervous system." | 2.49 | A rare adverse effect of metronidazole: nervous system symptoms. ( Kafadar, I; Klç, BA; Moustafa, F; Yalçın, K, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kafadar, I | 1 |
Moustafa, F | 1 |
Yalçın, K | 1 |
Klç, BA | 1 |
Çekin, AH | 1 |
Şahintürk, Y | 1 |
Akbay Harmandar, F | 1 |
Uyar, S | 1 |
Yolcular, BO | 1 |
Çekin, Y | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
To Determine the Effect of Honey Enema in the Treatment of Patients With Acute Pouchitis (Pilot Study)[NCT02201186] | Phase 2 | 10 participants (Actual) | Interventional | 2014-10-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for metronidazole and Dizziness
Article | Year |
---|---|
A rare adverse effect of metronidazole: nervous system symptoms.
Topics: Anti-Infective Agents; Ataxia; Child, Preschool; Convalescence; Dizziness; Dysentery, Amebic; Headac | 2013 |
1 trial available for metronidazole and Dizziness
Article | Year |
---|---|
Use of probiotics as an adjuvant to sequential H. pylori eradication therapy: impact on eradication rates, treatment resistance, treatment-related side effects, and patient compliance.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adult; Amoxicillin; Anorexia; Anti-Bacteria | 2017 |