metronidazole has been researched along with Diseases of Pharynx in 13 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the use of metronidazole as a prophylactic agent against pharyngocutaneous fistula (PCF) formation." | 9.15 | Pharyngocutaneous fistula complicating laryngectomy: can metronidazole help? ( Dimaka, K; Kourousis, C; Mallis, A; Margaritis, V; Mastronikolis, NS; Naxakis, SS; Panogeorgou, T; Papadas, TA; Stathas, T; Stavrou, S, 2011) |
| " An evaluation of the different radiotherapy schedules used during this period allowed a dose-response curve to be constructed." | 5.27 | Pharyngo-cutaneous fistulae after laryngectomy. Influence of previous radiotherapy and prophylactic metronidazole. ( Elbrønd, O; Johansen, LV; Overgaard, J, 1988) |
| "To evaluate the use of metronidazole as a prophylactic agent against pharyngocutaneous fistula (PCF) formation." | 5.15 | Pharyngocutaneous fistula complicating laryngectomy: can metronidazole help? ( Dimaka, K; Kourousis, C; Mallis, A; Margaritis, V; Mastronikolis, NS; Naxakis, SS; Panogeorgou, T; Papadas, TA; Stathas, T; Stavrou, S, 2011) |
| "The majority of patients with PPA were effectively managed by abscess incision, tonsillectomy, and penicillin G ± metronidazole." | 4.12 | Clinical evaluation of antibiotic regimens in patients with surgically verified parapharyngeal abscess: a prospective observational study. ( Andersen, C; Christensen, AL; Danstrup, CS; Døssing, H; Greve, T; Hahn, P; Kjeldsen, A; Klug, TE; Mikkelsen, S; Petersen, NK; Rusan, M, 2022) |
| "All patients with acute tonsillitis, peritonsillar abscess (PTA), and parapharyngeal abscess admitted to the Ear-Nose-Throat Department, Aarhus University Hospital, in the 2001-2014 period were included in the study." | 1.51 | Adherence to antibiotic guidelines in the treatment of acute pharyngeal infections. ( Danstrup, CS; Klug, TE; Øhrstrøm, MT, 2019) |
| " An evaluation of the different radiotherapy schedules used during this period allowed a dose-response curve to be constructed." | 1.27 | Pharyngo-cutaneous fistulae after laryngectomy. Influence of previous radiotherapy and prophylactic metronidazole. ( Elbrønd, O; Johansen, LV; Overgaard, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Klug, TE | 2 |
| Andersen, C | 1 |
| Hahn, P | 1 |
| Danstrup, CS | 2 |
| Petersen, NK | 1 |
| Mikkelsen, S | 1 |
| Døssing, H | 1 |
| Christensen, AL | 1 |
| Rusan, M | 1 |
| Kjeldsen, A | 1 |
| Greve, T | 1 |
| Del Carmen Martínez-Herrero, M | 1 |
| González-González, F | 1 |
| López-Márquez, I | 1 |
| García-Peña, FJ | 1 |
| Sansano-Maestre, J | 1 |
| Martínez-Díaz, RA | 1 |
| Ponce-Gordo, F | 1 |
| Garijo-Toledo, MM | 1 |
| Gómez-Muñoz, MT | 1 |
| Øhrstrøm, MT | 1 |
| Bali, R | 1 |
| Sharma, P | 1 |
| Gaba, S | 1 |
| Aladag, I | 1 |
| Eyibilen, A | 1 |
| Guven, M | 1 |
| Erkokmaz, U | 1 |
| Stathas, T | 1 |
| Mallis, A | 1 |
| Mastronikolis, NS | 1 |
| Naxakis, SS | 1 |
| Dimaka, K | 1 |
| Panogeorgou, T | 1 |
| Stavrou, S | 1 |
| Margaritis, V | 1 |
| Kourousis, C | 1 |
| Papadas, TA | 1 |
| Scotton, W | 1 |
| Cobb, R | 1 |
| Pang, L | 1 |
| Nixon, I | 1 |
| Joshi, A | 1 |
| Jeannon, JP | 1 |
| Oakley, R | 1 |
| French, G | 1 |
| Hemsley, C | 1 |
| Simo, R | 1 |
| Sathia, L | 1 |
| Ellis, B | 1 |
| Phillip, S | 1 |
| Winston, A | 1 |
| Smith, A | 1 |
| Innes, AJ | 1 |
| Windle-Taylor, PC | 1 |
| Harrison, DF | 1 |
| Bates, G | 1 |
| Tucker, RL | 1 |
| Ford, S | 1 |
| Mattix, ME | 1 |
| Sethi, DS | 1 |
| Chew, CT | 1 |
| Barrett, AP | 1 |
| Johansen, LV | 1 |
| Overgaard, J | 1 |
| Elbrønd, O | 1 |
2 trials available for metronidazole and Diseases of Pharynx
| Article | Year |
|---|---|
Use of metronidazole as part of an empirical antibiotic regimen after incision and drainage of infections of the odontogenic spaces.
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Bacteriological Techniq | 2015 |
Pharyngocutaneous fistula complicating laryngectomy: can metronidazole help?
Topics: Aged; Anti-Infective Agents; Combined Modality Therapy; Cutaneous Fistula; Female; Humans; Incidence | 2011 |
11 other studies available for metronidazole and Diseases of Pharynx
| Article | Year |
|---|---|
Clinical evaluation of antibiotic regimens in patients with surgically verified parapharyngeal abscess: a prospective observational study.
Topics: Abscess; Adult; Anti-Bacterial Agents; Humans; Metronidazole; Pharyngeal Diseases; Tonsillectomy | 2022 |
Oropharyngeal Trichomonosis Due to Trichomonas gypaetinii in a Cinereous Vulture ( Aegypius monachus) Fledgling in Spain.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Falconiformes; Metronidazole; Mouth Diseases; | 2019 |
Adherence to antibiotic guidelines in the treatment of acute pharyngeal infections.
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Denmark; Drug Prescriptions; Female; Guideline Adherenc | 2019 |
Effects of helicobacter pylori eradication on chronic nonspecific pharyngeal symptoms.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Chronic Disease; Cohort | 2008 |
Post-operative wound infection in salvage laryngectomy: does antibiotic prophylaxis have an impact?
Topics: Administration, Intravenous; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Cohort Studi | 2012 |
Pharyngeal gonorrhoea - is dual therapy the way forward?
Topics: Anti-Bacterial Agents; Azithromycin; Cefixime; Chlamydia Infections; Doxycycline; Drug Therapy, Comb | 2007 |
The role of metronidazole in the prevention of fistulae following total laryngectomy.
Topics: Bacterial Infections; Fistula; Humans; Laryngeal Neoplasms; Laryngectomy; Metronidazole; Pharyngeal | 1980 |
Thyroid adenocarcinoma in a bald eagle (Haliaeetus leukocephalus).
Topics: Adenocarcinoma; Animals; Antitrichomonal Agents; Bird Diseases; Eagles; Female; Hemorrhage; Metronid | 1999 |
Retropharyngeal abscess--the foreign body connection.
Topics: Abscess; Adult; Aged; Airway Obstruction; Female; Foreign Bodies; Humans; Male; Metronidazole; Middl | 1991 |
Metronidazole in the management of anaerobic neck infection in acute leukemia.
Topics: Adult; Bacteria, Anaerobic; Bacterial Infections; Humans; Leukemia, Myeloid; Male; Metronidazole; Ne | 1988 |
Pharyngo-cutaneous fistulae after laryngectomy. Influence of previous radiotherapy and prophylactic metronidazole.
Topics: Fistula; Humans; Laryngeal Neoplasms; Laryngectomy; Metronidazole; Pharyngeal Diseases; Radiation In | 1988 |