metronidazole has been researched along with Diseases in Twins in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Diseases in Twins: Disorders affecting TWINS, one or both, at any age.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 2 (66.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Herzog, D | 1 |
Hammer, B | 1 |
Neuweiler, J | 1 |
Werder, E | 1 |
Jensen, LM | 1 |
Jørgensen, JS | 1 |
Lidegaard, O | 1 |
Brinsden, PR | 1 |
Weber, T | 1 |
Metze, H | 1 |
van Bergen, A | 1 |
3 other studies available for metronidazole and Diseases in Twins
Article | Year |
---|---|
[Chronic giardiasis with intestinal dwarfism and delayed puberty in immunoglobulin deficiency syndrome: complete catch-up growth after therapy].
Topics: Adolescent; Adult; Age Determination by Skeleton; Antiprotozoal Agents; Child; Chronic Disease; Dise | 1998 |
Spontaneous abortion of one twin with Down's syndrome followed by delivery of the second twin 14 weeks later; a case report.
Topics: Abortion, Spontaneous; Adult; Chorioamnionitis; Diseases in Twins; Down Syndrome; Embryo Transfer; F | 1991 |
[Trichomonas infections in premature infants].
Topics: Adult; Diseases in Twins; Female; Hematuria; Humans; Infant, Newborn; Infant, Premature, Diseases; M | 1971 |