metronidazole has been researched along with Diseases, Occupational in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Mites were found in sputum in 121 persons who were then treated with metronidazole, twice a day with a daily dosage of 0." | 1.33 | [Survey and treatment of pulmonary acariasis among the workers involving in traditional Chinese medicinal materials]. ( Chen, XB; Hu, SF; Ru, XY; Shao, XY; Xia, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCormick, DF | 1 |
| Rahman, M | 1 |
| Zadrozny, S | 1 |
| Alam, A | 1 |
| Ashraf, L | 1 |
| Neilsen, GA | 1 |
| Kelly, R | 1 |
| Menezes, P | 1 |
| Miller, WC | 1 |
| Hoffman, IF | 1 |
| Xia, H | 1 |
| Hu, SF | 1 |
| Chen, XB | 1 |
| Ru, XY | 1 |
| Shao, XY | 1 |
| Tsimmerman, IaS | 1 |
| Kiseleva, RP | 1 |
| Freĭnd, GG | 1 |
| Schilling, D | 1 |
| Messerer, P | 1 |
| Ott, MG | 1 |
| Schauwecker, P | 1 |
| Zober, A | 1 |
| Riemann, JF | 1 |
1 trial available for metronidazole and Diseases, Occupational
| Article | Year |
|---|---|
Prevention and control of sexually transmissible infections among hotel-based female sex workers in Dhaka, Bangladesh.
Topics: Adolescent; Anti-Bacterial Agents; Azithromycin; Bangladesh; Candidiasis, Vulvovaginal; Cefixime; Ch | 2013 |
3 other studies available for metronidazole and Diseases, Occupational
| Article | Year |
|---|---|
[Survey and treatment of pulmonary acariasis among the workers involving in traditional Chinese medicinal materials].
Topics: Adolescent; Adult; Anti-Infective Agents; Drugs, Chinese Herbal; Female; Humans; Lung Diseases, Para | 2005 |
[The validation and effect of the prophylactic (antirelapse) treatment of peptic ulcer patients with chlorozil and metronidazole].
Topics: Adult; Anti-Ulcer Agents; Choline; Drug Evaluation; Duodenal Ulcer; Female; Follow-Up Studies; Human | 1996 |
[Dyspepsia and Helicobacter pylori infection in employees of a large industry. Results of a prospective BASF Helicobacter pylori prevention campaign].
Topics: Adolescent; Adult; Clarithromycin; Drug Therapy, Combination; Dyspepsia; Female; Gastritis; Germany; | 2002 |