metronidazole has been researched along with Disease, Pulmonary in 19 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred forty patients with pleuropulmonary amebiasis were classified radiographically in order to rationalize therapy based on the use of metronidazole." | 7.66 | The treatment of pleuropulmonary amebiasis with metronidazole. ( Cameron, EW, 1978) |
| " In this randomized study, the efficacy of metronidazole was compared with clindamycin in the treatment of patients with anaerobic lung abscess or necrotizing pneumonia." | 5.05 | Metronidazole vs clindamycin treatment of anerobic pulmonary infection. Failure of metronidazole therapy. ( Perlino, CA, 1981) |
| "One hundred forty patients with pleuropulmonary amebiasis were classified radiographically in order to rationalize therapy based on the use of metronidazole." | 3.66 | The treatment of pleuropulmonary amebiasis with metronidazole. ( Cameron, EW, 1978) |
| "Pulmonary abscess has been rarely reported as a complication of other bronchoscopic procedures such as endobronchial ultrasound-guided needle biopsy, however, to our knowledge this is the first reported case of pulmonary abscess complicating peripheral lung cryobiopsy." | 1.43 | Pulmonary Abscess as a Complication of Transbronchial Lung Cryobiopsy. ( Edell, ES; Kern, RM; Maldonado, F; Midthun, DE; Skalski, JH, 2016) |
| "Treatment with metronidazole (1." | 1.33 | [Amoebic infections of the lung and pleura]. ( Alaoui Yazidi, A; Bahlaoui, A; Bakhatar, A; El Biaze, M; El Meziane, A; Loudadssi, F; Rachid, H; Yassine, N, 2005) |
| "A survey on pulmonary acariasis was carried out in the grain store and in the Chinese medicinal herb plant." | 1.28 | [Clinical manifestation and treatment of pulmonary acariasis]. ( Chen, XB; Hu, SF; Sun, X, 1990) |
| "Of 33 patients with amoebic liver abscess (ALA) seen over a 5-year period, 24 had intrathoracic complications." | 1.27 | Intrathoracic complications of amoebic liver abscess. ( Aderounmu, A; Adeyemo, AO, 1984) |
| "Anaerobic infections are reviewed with emphasis on management." | 1.25 | Management of anaerobic infections. ( Bartlett, JG; Chow, AW; Finegold, SM; Flora, DJ; Gorbach, SL; Harder, EJ; Tally, FP, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Skalski, JH | 1 |
| Kern, RM | 1 |
| Midthun, DE | 1 |
| Edell, ES | 1 |
| Maldonado, F | 1 |
| Liu, J | 1 |
| Li, S | 1 |
| Li, H | 1 |
| Fan, Y | 1 |
| Yang, H | 1 |
| Xu, H | 1 |
| Shen, Y | 1 |
| Zhao, S | 1 |
| Englert, C | 1 |
| Aebert, H | 1 |
| Lenhart, M | 1 |
| Solleder, A | 1 |
| Nerlich, M | 1 |
| Neumann, C | 1 |
| Rachid, H | 1 |
| Alaoui Yazidi, A | 1 |
| Loudadssi, F | 1 |
| El Biaze, M | 1 |
| Bakhatar, A | 1 |
| Yassine, N | 1 |
| El Meziane, A | 1 |
| Bahlaoui, A | 1 |
| Nigam, P | 1 |
| Kapoor, KK | 1 |
| Gupta, RK | 1 |
| Gupta, AK | 1 |
| Goyal, BM | 1 |
| Adeyemo, AO | 1 |
| Aderounmu, A | 1 |
| Perlino, CA | 1 |
| Li, XY | 1 |
| Stallworth, JR | 1 |
| Carroll, JM | 1 |
| Chung, DA | 1 |
| Reiss, M | 1 |
| Reiss, G | 1 |
| Wasfy, AA | 1 |
| Shoeb, S | 1 |
| El-Mashad, A | 1 |
| El-Ebrashy, N | 1 |
| Higazi, A | 1 |
| Gaber, A | 1 |
| El-Tony, O | 1 |
| Cameron, EW | 1 |
| Finegold, SM | 2 |
| Bartlett, JG | 1 |
| Chow, AW | 1 |
| Flora, DJ | 1 |
| Gorbach, SL | 1 |
| Harder, EJ | 1 |
| Tally, FP | 1 |
| Chen, XB | 1 |
| Sun, X | 1 |
| Hu, SF | 1 |
| Asorey Carballeira, A | 1 |
| Alguacil Muñoz, A | 1 |
| Guerra Vales, JM | 1 |
| Vilalta Castel, E | 1 |
| Rao, NR | 1 |
| Reddy, VV | 1 |
| Rosenblatt, JE | 1 |
| Antani, JA | 1 |
| Srinivas, HV | 1 |
2 reviews available for metronidazole and Disease, Pulmonary
| Article | Year |
|---|---|
[Bad breath--etiological, diagnostic and therapeutic problems].
Topics: Anti-Bacterial Agents; Diagnosis, Differential; Gastrointestinal Diseases; Halitosis; Humans; Lung D | 2000 |
[Invasive amebiasis (II): Extra-intestinal forms and complications. Parasitological and serological diagnosis. Treatment].
Topics: Amebiasis; Amebicides; Animals; Anti-Bacterial Agents; Brain Abscess; Digestive System Diseases; Eme | 1985 |
3 trials available for metronidazole and Disease, Pulmonary
| Article | Year |
|---|---|
Metronidazole in pulmonary anaerobic infection.
Topics: Adolescent; Adult; Bacteria, Anaerobic; Bacterial Infections; Clinical Trials as Topic; Female; Huma | 1983 |
Metronidazole vs clindamycin treatment of anerobic pulmonary infection. Failure of metronidazole therapy.
Topics: Adult; Bacterial Infections; Clindamycin; Clinical Trials as Topic; Female; Humans; Lung Abscess; Lu | 1981 |
Treatment of tropical pulmonary eosinophilia with metronidazole.
Topics: Blood Sedimentation; Clinical Trials as Topic; Eosinophilia; Humans; India; Leukocyte Count; Lung Di | 1973 |
14 other studies available for metronidazole and Disease, Pulmonary
| Article | Year |
|---|---|
Pulmonary Abscess as a Complication of Transbronchial Lung Cryobiopsy.
Topics: Anti-Bacterial Agents; Biopsy; Bronchoscopy; Humans; Levofloxacin; Lung; Lung Abscess; Lung Diseases | 2016 |
Bronchopulmonary Disease Caused by Flagellated Protozoa Infection in 15 Chinese Children.
Topics: Antiprotozoal Agents; Bronchoalveolar Lavage Fluid; Child; Child, Preschool; Female; Humans; Infant; | 2017 |
Thoracic spondylitis from a mycotic (Streptococcus pneumoniae) aortic aneurysm: a case report.
Topics: Aneurysm, Infected; Anti-Bacterial Agents; Aortic Aneurysm, Thoracic; Blood Vessel Prosthesis Implan | 2004 |
[Amoebic infections of the lung and pleura].
Topics: Adult; Animals; Antiprotozoal Agents; Drainage; Entamoeba histolytica; Entamoebiasis; Humans; Liver | 2005 |
Intrathoracic complications of amoebic liver abscess.
Topics: Adolescent; Adult; Central Nervous System Diseases; Child; Drainage; Empyema; Female; Fistula; Human | 1984 |
[Therapeutic effect of metronidazole on anaerobic pulmonary and pleural infections].
Topics: Anaerobiosis; Bacteria; Bacterial Infections; Humans; Lung Diseases; Metronidazole; Pleural Diseases | 1982 |
Lemierre's syndrome: new insights into an old disease.
Topics: Adolescent; Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Drug Therapy, Combination; Female; F | 1997 |
Infected lung cysts.
Topics: Adult; Bacterial Infections; Clindamycin; Cysts; Drug Therapy, Combination; Female; Humans; Lung Dis | 1999 |
Detection of anaerobic respiratory bacteria with a new therapeutic approach.
Topics: Adult; Aged; Anaerobiosis; Bacteria; Female; Humans; Lung Diseases; Male; Metronidazole; Middle Aged | 1978 |
The treatment of pleuropulmonary amebiasis with metronidazole.
Topics: Adolescent; Adult; Aged; Amebiasis; Child; Child, Preschool; Empyema; Female; Humans; Lung Diseases; | 1978 |
Management of anaerobic infections.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacterial Infections; Bacteroides Infections; Bone Diseases; Br | 1975 |
[Clinical manifestation and treatment of pulmonary acariasis].
Topics: Adolescent; Adult; Aged; Female; Humans; Lung Diseases; Male; Metronidazole; Middle Aged; Mite Infes | 1990 |
Practical aspects of anaerobic sepsis.
Topics: Abscess; Anaerobiosis; Arthritis, Infectious; Bacterial Infections; Bacteroides; Bone Diseases; Brai | 1973 |
Clinical evaluation of metronidazole in tropical pulmonary eosinophilia: a preliminary report.
Topics: Adolescent; Adult; Eosinophilia; Humans; Lung Diseases; Metronidazole; Middle Aged | 1973 |