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metronidazole and Diplopia

metronidazole has been researched along with Diplopia in 4 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Diplopia: A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.

Research Excerpts

ExcerptRelevanceReference
"To report the onset of neuro-ophthalmological adverse effects in two children treated with metronidazole for amoebic dysentery."1.43[Neuro-ophthalmic adverse effects of metronidazole treatment in children: Two case studies]. ( Bouladi, M; Bouraoui, R; El Matri, L; Limaiem, R; Mghaieth, F, 2016)
"Gradual development of diplopia over 6 months was the first clinical manifestation."1.29[Pituitary abscess, treated by medication]. ( Ba Zeze, V; Boni, N; Datie, A; Dechambenoit, G; Grunitzky, EK; Kakou, M; Santini, JJ, 1993)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bouraoui, R1
Limaiem, R1
Bouladi, M1
Mghaieth, F1
El Matri, L1
Kromberg, R1
Mozet, C1
Fritzsch, D1
Dawczynski, J1
Dietz, A1
Dechambenoit, G1
Datie, A1
Grunitzky, EK1
Ba Zeze, V1
Boni, N1
Kakou, M1
Santini, JJ1
Feldman, DP1
Picerno, NA1
Porubsky, ES1

Other Studies

4 other studies available for metronidazole and Diplopia

ArticleYear
[Neuro-ophthalmic adverse effects of metronidazole treatment in children: Two case studies].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2016, Volume: 23, Issue:2

    Topics: Antiprotozoal Agents; Child; Diplopia; Female; Humans; Male; Metronidazole; Vision Disorders

2016
[A rare complication of acute sinusitis].
    Laryngo- rhino- otologie, 2012, Volume: 91, Issue:6

    Topics: Aged; Cavernous Sinus Thrombosis; Cefuroxime; Combined Modality Therapy; Decompression, Surgical; Di

2012
[Pituitary abscess, treated by medication].
    Revue neurologique, 1993, Volume: 149, Issue:10

    Topics: Abscess; Adult; Cefotaxime; Diplopia; Drug Therapy, Combination; Humans; Male; Metronidazole; Netilm

1993
Cavernous sinus thrombosis complicating odontogenic parapharyngeal space neck abscess: a case report and discussion.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2000, Volume: 123, Issue:6

    Topics: Aged; Anti-Infective Agents; Cavernous Sinus Thrombosis; Ceftriaxone; Cephalosporins; Combined Modal

2000