metronidazole has been researched along with Diplopia in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Diplopia: A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.
Excerpt | Relevance | Reference |
---|---|---|
"To report the onset of neuro-ophthalmological adverse effects in two children treated with metronidazole for amoebic dysentery." | 1.43 | [Neuro-ophthalmic adverse effects of metronidazole treatment in children: Two case studies]. ( Bouladi, M; Bouraoui, R; El Matri, L; Limaiem, R; Mghaieth, F, 2016) |
"Gradual development of diplopia over 6 months was the first clinical manifestation." | 1.29 | [Pituitary abscess, treated by medication]. ( Ba Zeze, V; Boni, N; Datie, A; Dechambenoit, G; Grunitzky, EK; Kakou, M; Santini, JJ, 1993) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bouraoui, R | 1 |
Limaiem, R | 1 |
Bouladi, M | 1 |
Mghaieth, F | 1 |
El Matri, L | 1 |
Kromberg, R | 1 |
Mozet, C | 1 |
Fritzsch, D | 1 |
Dawczynski, J | 1 |
Dietz, A | 1 |
Dechambenoit, G | 1 |
Datie, A | 1 |
Grunitzky, EK | 1 |
Ba Zeze, V | 1 |
Boni, N | 1 |
Kakou, M | 1 |
Santini, JJ | 1 |
Feldman, DP | 1 |
Picerno, NA | 1 |
Porubsky, ES | 1 |
4 other studies available for metronidazole and Diplopia
Article | Year |
---|---|
[Neuro-ophthalmic adverse effects of metronidazole treatment in children: Two case studies].
Topics: Antiprotozoal Agents; Child; Diplopia; Female; Humans; Male; Metronidazole; Vision Disorders | 2016 |
[A rare complication of acute sinusitis].
Topics: Aged; Cavernous Sinus Thrombosis; Cefuroxime; Combined Modality Therapy; Decompression, Surgical; Di | 2012 |
[Pituitary abscess, treated by medication].
Topics: Abscess; Adult; Cefotaxime; Diplopia; Drug Therapy, Combination; Humans; Male; Metronidazole; Netilm | 1993 |
Cavernous sinus thrombosis complicating odontogenic parapharyngeal space neck abscess: a case report and discussion.
Topics: Aged; Anti-Infective Agents; Cavernous Sinus Thrombosis; Ceftriaxone; Cephalosporins; Combined Modal | 2000 |