metronidazole has been researched along with Dilatation, Pathologic in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Dilatation, Pathologic: The condition of an anatomical structure's being dilated beyond normal dimensions.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tong, Y | 1 |
| Hao, Y | 1 |
| Gao, X | 1 |
| Sun, Y | 1 |
| Wang, W | 1 |
| Modi, BP | 1 |
| Langer, M | 1 |
| Duggan, C | 1 |
| Kim, HB | 1 |
| Jaksic, T | 1 |
| Barry, RE | 2 |
| Chow, AW | 1 |
| Billesdon, J | 1 |
| Benfield, JR | 1 |
| Nicell, P | 1 |
| Bray, GA | 1 |
2 trials available for metronidazole and Dilatation, Pathologic
| Article | Year |
|---|---|
Dexamethasone combined metronidazole on mammary duct ectasia and its relationship with serum IL-10 and IL-17.
Topics: Dexamethasone; Dilatation, Pathologic; Humans; Interleukin-10; Interleukin-17; Metronidazole | 2020 |
Role of intestinal microflora in colonic pseudoobstruction complicating jejunoileal bypass.
Topics: Bacteria; Clinical Trials as Topic; Colonic Diseases; Dilatation, Pathologic; Drug Therapy, Combinat | 1977 |
2 other studies available for metronidazole and Dilatation, Pathologic
| Article | Year |
|---|---|
Serial transverse enteroplasty for management of refractory D-lactic acidosis in short-bowel syndrome.
Topics: Acidosis, Lactic; Adolescent; Anti-Bacterial Agents; Bacteria; Digestive System Surgical Procedures; | 2006 |
Colonic pseudo-obstruction: a new complication of jejunoileal bypass.
Topics: Adult; Clindamycin; Colon; Colonic Diseases; Diagnosis, Differential; Dilatation, Pathologic; Humans | 1975 |