metronidazole has been researched along with Dermoid in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intracranial dermoid cysts are rare, but can cause recurrent bacterial or aseptic meningitis, abscesses or mass effect." | 1.35 | Posterior fossa dermoid cyst with sinus tract and meningitis in a toddler. ( Abbott, IR; Douvoyiannis, M; Goldman, DL; Litman, N, 2008) |
| "Total excision of dermal sinus tract, dermoid cyst, and the intramedullary abscess by means of a L2-S3 laminectomy, followed by antibiotic therapy resulted in good functional recovery." | 1.35 | Infected lumbar dermoid cyst presenting with tetraparesis secondary to holocord central lesion. ( Cekinmez, M; Erdogan, B; Sener, L; Tufan, K, 2008) |
| "Midline nasal dermoid cysts are congenital lesions resulting from aberrant embryological development." | 1.29 | Nasal dermoid sinus cysts: an unusual presentation, computed tomographic scan findings, and surgical results. ( Armstrong, DC; Bortoluzzi, P; Posnick, JC, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Douvoyiannis, M | 1 |
| Goldman, DL | 1 |
| Abbott, IR | 1 |
| Litman, N | 1 |
| Tufan, K | 1 |
| Cekinmez, M | 1 |
| Sener, L | 1 |
| Erdogan, B | 1 |
| Posnick, JC | 1 |
| Bortoluzzi, P | 1 |
| Armstrong, DC | 1 |
3 other studies available for metronidazole and Dermoid
| Article | Year |
|---|---|
Posterior fossa dermoid cyst with sinus tract and meningitis in a toddler.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Cranial Sinuses; Dermoid Cyst; Humans; Infant; Infratent | 2008 |
Infected lumbar dermoid cyst presenting with tetraparesis secondary to holocord central lesion.
Topics: Abscess; Cefotaxime; Child; Dermoid Cyst; Drug Therapy, Combination; Follow-Up Studies; Gram-Negativ | 2008 |
Nasal dermoid sinus cysts: an unusual presentation, computed tomographic scan findings, and surgical results.
Topics: Bone Transplantation; Cellulitis; Child, Preschool; Cloxacillin; Combined Modality Therapy; Coronary | 1994 |