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metronidazole and Dermatitis

metronidazole has been researched along with Dermatitis in 13 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Dermatitis: Any inflammation of the skin.

Research Excerpts

ExcerptRelevanceReference
" Since the dermatitis caused by metronidazole gel was also distinguished, the redness was improved when the application was stopped."7.96[A Case of Dermatitis Caused by Metronidazole Gel That Needed to Be Differentiated from Breast Cancer Skin Metastasis]. ( Asano, Y; Hirakawa, K; Ishihara, S; Kashiwagi, S; Kawano, Y; Kouhashi, R; Morisaki, T; Noda, S; Ohira, M; Onoda, N; Takashima, T; Tauchi, Y; Yabumoto, A, 2020)
"We investigated the effects of 1-4% ointments of metronidazole and tinidazole (derivatives of nitroimidazole) on models of inflammatory dermatitis evoked by antigen, hapten and monoclonal anti-dinitrophenol (DNP) IgE antibody in mice."7.72Effects of metronidazole and tinidazole ointments on models for inflammatory dermatitis in mice. ( Ito, Y; Nishimuta, K, 2003)
"Metronidazole was administered (500 mg daily the first month, 250 mg daily the second month and, in some cases, 250 mg every other day the following months) to 62 patients suffering from rosacea or perioral dermatitis."7.66[Metronidazole therapy in rosacea (author's transl)]. ( Guilhou, E; Guilhou, JJ; Malbos, S; Meynadier, J, 1979)
" Since the dermatitis caused by metronidazole gel was also distinguished, the redness was improved when the application was stopped."3.96[A Case of Dermatitis Caused by Metronidazole Gel That Needed to Be Differentiated from Breast Cancer Skin Metastasis]. ( Asano, Y; Hirakawa, K; Ishihara, S; Kashiwagi, S; Kawano, Y; Kouhashi, R; Morisaki, T; Noda, S; Ohira, M; Onoda, N; Takashima, T; Tauchi, Y; Yabumoto, A, 2020)
"We investigated the effects of 1-4% ointments of metronidazole and tinidazole (derivatives of nitroimidazole) on models of inflammatory dermatitis evoked by antigen, hapten and monoclonal anti-dinitrophenol (DNP) IgE antibody in mice."3.72Effects of metronidazole and tinidazole ointments on models for inflammatory dermatitis in mice. ( Ito, Y; Nishimuta, K, 2003)
"Metronidazole was administered (500 mg daily the first month, 250 mg daily the second month and, in some cases, 250 mg every other day the following months) to 62 patients suffering from rosacea or perioral dermatitis."3.66[Metronidazole therapy in rosacea (author's transl)]. ( Guilhou, E; Guilhou, JJ; Malbos, S; Meynadier, J, 1979)
"Giardia infection was believed responsible for chronic diarrhea, weight loss, lethargy, inappetence, and dermatitis in a 4-year-old Thoroughbred horse."1.27Giardiasis in a horse. ( Kirkpatrick, CE; Skand, DL, 1985)
"Pneumatosis cystoides intestinalis was a sequal in two patients."1.26Bypass enteropathy: an inflammatory process in the excluded segment with systemic complications. ( Ament, ME; Drenick, EJ; Finegold, SM; Passaro, E, 1977)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's5 (38.46)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Ishihara, S1
Kashiwagi, S1
Asano, Y1
Kawano, Y1
Kouhashi, R1
Yabumoto, A1
Tauchi, Y1
Morisaki, T1
Noda, S1
Takashima, T1
Onoda, N1
Hirakawa, K1
Ohira, M1
Nishimuta, K1
Ito, Y1
Nguyen, V1
Eichenfield, LF1
Hogan, DJ1
Roenigk, RK1
Guilhou, JJ1
Guilhou, E1
Malbos, S1
Meynadier, J1
Drenick, EJ2
Ament, ME1
Finegold, SM1
Passaro, E1
BaƱuls, J1
Ramon, D1
Aniz, E1
Jorda, E1
Torres, V1
Veien, NK1
Munkvad, JM1
Nielsen, AO1
Niordson, AM1
Stahl, D1
Thormann, J1
Roslyn, JJ1
Shelley, WB1
Shelley, ED1
Burmeister, V1
Shakhnes, IE1
Krepker, IaB1
Kirkpatrick, CE1
Skand, DL1

Reviews

1 review available for metronidazole and Dermatitis

ArticleYear
Perioral dermatitis.
    Current problems in dermatology, 1995, Volume: 22

    Topics: Adrenal Cortex Hormones; Adult; Aged; Child; Dermatitis; Diagnosis, Differential; Facial Dermatoses;

1995

Trials

1 trial available for metronidazole and Dermatitis

ArticleYear
Topical metronidazole in the treatment of perioral dermatitis.
    Journal of the American Academy of Dermatology, 1991, Volume: 24, Issue:2 Pt 1

    Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Dermatitis; Double-Blind Method;

1991

Other Studies

11 other studies available for metronidazole and Dermatitis

ArticleYear
[A Case of Dermatitis Caused by Metronidazole Gel That Needed to Be Differentiated from Breast Cancer Skin Metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:13

    Topics: Aged; Axilla; Breast Neoplasms; Dermatitis; Female; Humans; Metronidazole; Trastuzumab

2020
Effects of metronidazole and tinidazole ointments on models for inflammatory dermatitis in mice.
    Archives of dermatological research, 2003, Volume: 294, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Antipruritics; Capillary Permeability; D

2003
Periorificial dermatitis in children and adolescents.
    Journal of the American Academy of Dermatology, 2006, Volume: 55, Issue:5

    Topics: Administration, Oral; Administration, Topical; Adolescent; Adrenal Cortex Hormones; Anti-Infective A

2006
'Eye-catching' dermatitis for the skin surgeon.
    Ophthalmic plastic and reconstructive surgery, 1999, Volume: 15, Issue:3

    Topics: Anti-Bacterial Agents; Cryosurgery; Dermatitis; Eyelid Diseases; Humans; Hydrocortisone; Metronidazo

1999
[Metronidazole therapy in rosacea (author's transl)].
    Annales de dermatologie et de venereologie, 1979, Volume: 106, Issue:2

    Topics: Adult; Aged; Dermatitis; Female; Gastrointestinal Diseases; Humans; Male; Metronidazole; Middle Aged

1979
Bypass enteropathy: an inflammatory process in the excluded segment with systemic complications.
    The American journal of clinical nutrition, 1977, Volume: 30, Issue:1

    Topics: Adult; Albumins; Arthritis; Body Weight; Dermatitis; Diarrhea; Female; Humans; Ileum; Inflammation;

1977
Papular pruritic eruption with human immunodeficiency virus infection.
    International journal of dermatology, 1991, Volume: 30, Issue:11

    Topics: Adult; Dermatitis; Female; HIV Infections; Humans; Metronidazole; Pruritus; Zidovudine

1991
Cure of arthritis-dermatitis syndrome due to intestinal bypass by resection of nonfunctional segment of blind loop.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:5

    Topics: Arthritis; Blind Loop Syndrome; Dermatitis; Female; Humans; Jejunoileal Bypass; Metronidazole; Middl

1990
Unilateral demodectic rosacea.
    Journal of the American Academy of Dermatology, 1989, Volume: 20, Issue:5 Pt 2

    Topics: Adult; Dermatitis; Humans; Male; Metronidazole; Mite Infestations; Rosacea; Toluidines

1989
[Experience in the treatment of rosacea and perioral dermatitis with trichopol].
    Vestnik dermatologii i venerologii, 1985, Issue:3

    Topics: Adolescent; Adult; Aged; Dermatitis; Female; Humans; Male; Metronidazole; Middle Aged; Mouth; Rosace

1985
Giardiasis in a horse.
    Journal of the American Veterinary Medical Association, 1985, Jul-15, Volume: 187, Issue:2

    Topics: Animals; Dermatitis; Diarrhea; Giardiasis; Horse Diseases; Horses; Male; Metronidazole

1985